A Ravelli

Summary

Affiliation: G. Gaslini Institute
Country: Italy

Publications

  1. ncbi Clinical assessment in juvenile dermatomyositis
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Universita di Genova, Dipartimento di Pediatria, Italy
    Autoimmunity 39:197-203. 2006
  2. ncbi Development and validation of a preliminary definition of minimal disease activity in patients with juvenile idiopathic arthritis
    Silvia Magni-Manzoni
    Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S Matteo, Pavia, Italy
    Arthritis Rheum 59:1120-7. 2008
  3. ncbi Development and validation of a composite disease activity score for juvenile idiopathic arthritis
    Alessandro Consolaro
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, and the Università degli Studi di Verona, Verona, Italy
    Arthritis Rheum 61:658-66. 2009
  4. ncbi Parent and child acceptable symptom state in juvenile idiopathic arthritis
    Giovanni Filocamo
    Pediatria II, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genoa, Italy
    J Rheumatol 39:856-63. 2012
  5. ncbi Patients with antinuclear antibody-positive juvenile idiopathic arthritis constitute a homogeneous subgroup irrespective of the course of joint disease
    Angelo Ravelli
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 52:826-32. 2005
  6. ncbi Outcome in juvenile onset systemic lupus erythematosus
    Angelo Ravelli
    Dipartimento di Pediatria, Universita di Genova, Unita Operativa Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Italy
    Curr Opin Rheumatol 17:568-73. 2005
  7. ncbi Long-term outcome and prognostic factors of juvenile dermatomyositis: a multinational, multicenter study of 490 patients
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini and Università degli Studi di Genoa, Genoa, Italy
    Arthritis Care Res (Hoboken) 62:63-72. 2010
  8. ncbi Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    Angelo Ravelli
    Department of Pediatrics, Division of Pediatrics II, University of Genoa, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genoa, Italy
    J Pediatr 146:598-604. 2005
  9. ncbi Antiphospholipid syndrome
    Angelo Ravelli
    Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Largo G Gaslini, 5, 16147, Genoa, Italy
    Pediatr Clin North Am 52:469-91, vi. 2005
  10. ncbi Remission in juvenile idiopathic arthritis
    A Ravelli
    Dirigente Medico, Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    Clin Exp Rheumatol 24:S105-10. 2006

Detail Information

Publications90

  1. ncbi Clinical assessment in juvenile dermatomyositis
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Universita di Genova, Dipartimento di Pediatria, Italy
    Autoimmunity 39:197-203. 2006
    ....
  2. ncbi Development and validation of a preliminary definition of minimal disease activity in patients with juvenile idiopathic arthritis
    Silvia Magni-Manzoni
    Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S Matteo, Pavia, Italy
    Arthritis Rheum 59:1120-7. 2008
    ..To develop and validate a definition of minimal disease activity (MDA) in patients with juvenile idiopathic arthritis (JIA)...
  3. ncbi Development and validation of a composite disease activity score for juvenile idiopathic arthritis
    Alessandro Consolaro
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, and the Università degli Studi di Verona, Verona, Italy
    Arthritis Rheum 61:658-66. 2009
    ..To develop and validate a composite disease activity score for juvenile idiopathic arthritis (JIA), the Juvenile Arthritis Disease Activity Score (JADAS)...
  4. ncbi Parent and child acceptable symptom state in juvenile idiopathic arthritis
    Giovanni Filocamo
    Pediatria II, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genoa, Italy
    J Rheumatol 39:856-63. 2012
    ..To explore the parent and child acceptable symptom state in juvenile arthritis (JA-PASS and JA-CASS, respectively) and estimate the JA-PASS and JA-CASS cutoff values for outcome measures...
  5. ncbi Patients with antinuclear antibody-positive juvenile idiopathic arthritis constitute a homogeneous subgroup irrespective of the course of joint disease
    Angelo Ravelli
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 52:826-32. 2005
    ....
  6. ncbi Outcome in juvenile onset systemic lupus erythematosus
    Angelo Ravelli
    Dipartimento di Pediatria, Universita di Genova, Unita Operativa Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Italy
    Curr Opin Rheumatol 17:568-73. 2005
    ..This review summarizes the recent advances in the investigation on survival, accumulated damage, and health-related quality of life in patients with juvenile-onset systemic lupus erythematosus...
  7. ncbi Long-term outcome and prognostic factors of juvenile dermatomyositis: a multinational, multicenter study of 490 patients
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini and Università degli Studi di Genoa, Genoa, Italy
    Arthritis Care Res (Hoboken) 62:63-72. 2010
    ..To investigate the long-term outcome and prognostic factors of juvenile dermatomyositis (DM) through a multinational, multicenter study...
  8. ncbi Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    Angelo Ravelli
    Department of Pediatrics, Division of Pediatrics II, University of Genoa, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genoa, Italy
    J Pediatr 146:598-604. 2005
    ..To develop diagnostic guidelines for macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (S-JIA)...
  9. ncbi Antiphospholipid syndrome
    Angelo Ravelli
    Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Largo G Gaslini, 5, 16147, Genoa, Italy
    Pediatr Clin North Am 52:469-91, vi. 2005
    ....
  10. ncbi Remission in juvenile idiopathic arthritis
    A Ravelli
    Dirigente Medico, Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    Clin Exp Rheumatol 24:S105-10. 2006
    ..These findings highlight the critical need for therapies that have the capacity to induce sustained complete disease control of JIA...
  11. ncbi Early predictors of outcome in juvenile idiopathic arthritis
    A Ravelli
    Dipartimento di Pediatria, Universita di Genova, U O Pediatria II, IRCCS G Gaslini, Genova, Italy
    Clin Exp Rheumatol 21:S89-93. 2003
    ..Furthermore, a radiographic scoring system and a set of remission criteria specific for JIA should be developed...
  12. ncbi Adapted versions of the Sharp/van der Heijde score are reliable and valid for assessment of radiographic progression in juvenile idiopathic arthritis
    Angelo Ravelli
    Università degli Studi di Genoa, and IRCCS, Istituto G Gaslini, Genoa, Italy
    Arthritis Rheum 56:3087-95. 2007
    ..To develop adapted versions of the Sharp/van der Heijde radiographic scoring system for use in juvenile idiopathic arthritis (JIA), and to investigate their validity in JIA patients with polyarticular disease...
  13. ncbi Antinuclear antibody-positive patients should be grouped as a separate category in the classification of juvenile idiopathic arthritis
    Angelo Ravelli
    IRCCS G Gaslini and Università degli Studi di Genova, Genoa, Italy
    Arthritis Rheum 63:267-75. 2011
    ....
  14. ncbi Agreement between physicians and parents in rating functional ability of children with juvenile idiopathic arthritis
    Elena Palmisani
    Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G, Gaslini, Genova, Italy
    Pediatr Rheumatol Online J 5:23. 2007
    ..To investigate concordance between physicians and parents in rating the degree of functional ability of children with juvenile idiopathic arthritis (JIA)...
  15. ncbi Macrophage activation syndrome
    Angelo Ravelli
    Pediatria II, Istituto G Gaslini, Universita di Genova, Italy
    Curr Opin Rheumatol 14:548-52. 2002
    ..Cyclosporin A has been found effective in patients with corticosteroid-resistant MAS. A recent report has suggested that etanercept may be a useful adjunctive therapeutic agent...
  16. ncbi Glucocorticoids in paediatric rheumatology
    A Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Italy
    Clin Exp Rheumatol 29:S148-52. 2011
    ..Administration of GCs is associated with potentially deleterious adverse effects, some of which can be irreversible. This highlights the need of a judicious use of these medications and a careful monitoring of their toxicity...
  17. ncbi Juvenile idiopathic arthritis
    Angelo Ravelli
    Department of Paediatrics, University of Genoa and Institute G Gaslini, Genoa, Italy
    Lancet 369:767-78. 2007
    ....
  18. ncbi Impact of involvement of individual joint groups on subdimensions of functional ability scales in juvenile idiopathic arthritis
    S Meiorin
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, 16147 Genova, Italy
    Clin Exp Rheumatol 27:527-33. 2009
    ..To investigate the influence of arthritis in individual joint groups on subdimensions of functional ability questionnaires in children with juvenile idiopathic arthritis (JIA)...
  19. ncbi Macrophage activation syndrome in juvenile systemic lupus erythematosus: an under-recognized complication?
    A Pringe
    Istituto di Ricovero e Cura a Carattere Scientifico Giannina Gaslini, Genova, Italy, Hospital Pedro de Elizalde, Buenos Aires, Argentina
    Lupus 16:587-92. 2007
    ....
  20. ncbi Weighting improves the information provided by joint counts on the severity of arthritis and its impact on patients' well-being in juvenile idiopathic arthritis
    M Bandeira
    Departimento di Pediatria, , Istituto di Ricovero e Cura a Carattee Scientifico G. Gaslini, Genova, Italy
    Rheumatology (Oxford) 45:343-7. 2006
    ..CONCLUSION: Weighting improves the information provided by joint counts on the severity of arthritis and its impact on patients' well-being...
  21. ncbi Relative responsiveness of condition specific and generic health status measures in juvenile idiopathic arthritis
    C Moretti
    Dipartimento di Pediatria, , Istituto di Ricovero e Cura a Carattiere Scientifico, Policlinico S. Matteo, Pavia, Italy
    Ann Rheum Dis 64:257-61. 2005
    ..The relative evaluative properties of the generic health status instrument and the CHAQ should be further investigated...
  22. ncbi Cyclosporine A in juvenile idiopathic arthritis. Results of the PRCSG/PRINTO phase IV post marketing surveillance study
    N Ruperto
    IRCCS G Gaslini, Pediatria II Reumatologia, PRINTO, Genova, Italy
    Clin Exp Rheumatol 24:599-605. 2006
    ..To investigate the clinical use patterns, clinical effect and safety of cyclosporine A (CSA) in juvenile idiopathic arthritis (JIA) in the setting of routine clinical care...
  23. ncbi Does removal of aids/devices and help make a difference in the Childhood Health Assessment Questionnaire disability index?
    C Saad-Magalhaes
    IRCCS G Gaslini, Pediatria II, Reumatologia, PRINTO, Genova 16147, Italy
    Ann Rheum Dis 69:82-7. 2010
    ....
  24. ncbi Methotrexate improves the health-related quality of life of children with juvenile idiopathic arthritis
    A Cespedes-Cruz
    IRCCS G Gaslini, Pediatria II, Reumatologia, PRINTO, Largo Gaslini, 5, 16147 Genova, Italy
    Ann Rheum Dis 67:309-14. 2008
    ..To examine the change in health-related quality of life (HRQOL) and its determinants in children with juvenile idiopathic arthritis (JIA) treated with methotrexate (MTX)...
  25. ncbi Responsiveness of clinical measures to flare of disease activity in juvenile idiopathic arthritis
    S Magni-Manzoni
    Dipartimento di Pediatria, , Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo, Pavia, Italy
    Clin Exp Rheumatol 23:421-5. 2005
    ..CONCLUSION: Our analysis suggests that the swollen or painful joint counts are better suited than the count of joints with LROM for the assessment of disease flare in patients with JIA...
  26. ncbi Discordance between physician's and parent's global assessments in juvenile idiopathic arthritis
    F Sztajnbok
    Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    Rheumatology (Oxford) 46:141-5. 2007
    ..To investigate the discrepancy between physician's and parent's global assessments of disease status and the factors explaining discordance in patients with juvenile idiopathic arthritis (JIA)...
  27. ncbi Preliminary evidence that etanercept may reduce radiographic progression in juvenile idiopathic arthritis
    S Nielsen
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    Clin Exp Rheumatol 26:688-92. 2008
    ..To investigate the rate of radiographic progression, as measured with the carpo-metacarpal ratio (Poznanski score), during etanercept (ETN) therapy in children with polyarticular juvenile idiopathic arthritis (JIA)...
  28. ncbi Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: the Pediatric Rheumatology International Trials Organization multinational quality of life cohort study
    Sheila Oliveira
    IRCCS G Gaslini, Pediatria II, Reumatologia, Pediatric Rheumatology International Trials Organization, Genoa, Italy
    Arthritis Rheum 57:35-43. 2007
    ..To investigate the proxy-reported health-related quality of life (HRQOL) and its determinants in patients with juvenile idiopathic arthritis (JIA)...
  29. ncbi Inter-observer agreement of the physician's global assessment of disease activity in children with juvenile idiopathic arthritis
    A Falcone
    Dipartimento di Pediatria, , Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genova, Italy
    Clin Exp Rheumatol 23:113-6. 2005
    ..Analyses involving investigators from different countries are needed to determine whether these results can be generalized...
  30. ncbi The Paediatric Rheumatology International Trials Organization (PRINTO)
    N Ruperto
    IRCCS G Gaslini, Pediatria, Reumatologia, PRINTO, Genova, Italy
    Lupus 16:670-6. 2007
    ..The definition is now proposed for use in JSLE clinical trials, and may help physicians to decide if a child with SLE has responded adequately to therapy...
  31. ncbi A reappraisal of intra-articular corticosteroid therapy in juvenile idiopathic arthritis
    C Scott
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy, and 2School of Adolescent and Child Health, University of Cape Town, South Africa
    Clin Exp Rheumatol 28:774-81. 2010
    ..Furthermore, it is still unknown whether this therapy has a disease-modifying effect over the long-term. This review summarises the present information about the use of IAC therapy in children with JIA...
  32. ncbi Outcome of primary antiphospholipid syndrome in childhood
    M Gattorno
    Dipartimento di Pediatria, Universita di Genova, Pediatria II, Istituto G Gaslini, Italy
    Lupus 12:449-53. 2003
    ..In conclusion; our analysis suggests that some children who present with the features of primary APS may progress to develop SLE or lupus-like syndrome...
  33. ncbi MRI versus conventional measures of disease activity and structural damage in evaluating treatment efficacy in juvenile idiopathic arthritis
    C Malattia
    Correspondence to Clara Malattia, Pediatria II, Istituto Giannina Gaslini, Largo G Gaslini 5, Genova 16147, Italy
    Ann Rheum Dis 72:363-8. 2013
    ..To compare the American College of Rheumatology paediatric (ACRp) response criteria and conventional radiography with MRI findings in a cohort of patients with juvenile idiopathic arthritis...
  34. ncbi Health-related quality of life in juvenile-onset systemic lupus erythematosus and its relationship to disease activity and damage
    Nicolino Ruperto
    , Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genoa, Italy
    Arthritis Rheum 51:458-64. 2004
    ..HRQL may be affected by both disease activity and accumulated damage, particularly in the renal, central nervous, and musculoskeletal systems...
  35. ncbi Novel automated system for magnetic resonance imaging quantification of the inflamed synovial membrane volume in patients with juvenile idiopathic arthritis
    C Malattia
    Istituto Giannina Gaslini and Università di Genova, Genova, Italy
    Arthritis Care Res (Hoboken) 64:1657-64. 2012
    ....
  36. ncbi Relationship between damage accrual, disease flares and cumulative drug therapies in juvenile-onset systemic lupus erythematosus
    M Bandeira
    Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    Lupus 15:515-20. 2006
    ....
  37. ncbi Unilateral destructive wrist synovitis in juvenile idiopathic arthritis
    R Cassone
    Dipartimento di Pediatria, , Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genova, Italy
    Clin Exp Rheumatol 22:637-42. 2004
    ..CONCLUSION: Unilateral erosive wrist synovitis seems to be uncommon in JIA. Patients with unilateral wrist synovitis may be at risk of a destructive course irrespective of the JIA onset subtype...
  38. ncbi Course of joint disease in patients with antinuclear antibody-positive juvenile idiopathic arthritis
    Enrico Felici
    Dipartimento di Pediatria, , , Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genova, Italy
    J Rheumatol 32:1805-10. 2005
    ..The early occurrence of ankle and/or wrist disease may indicate a higher likelihood of arthritis progression...
  39. ncbi Correlation between juvenile idiopathic arthritis activity and damage measures in early, advanced, and longstanding disease
    Elena Palmisani
    Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genoa, Italy
    Arthritis Rheum 55:843-9. 2006
    ..These findings have important implications for clinical trials because they indicate that the responsiveness of some variables and their correlation with other variables change as disease duration changes...
  40. ncbi Development and validation of a clinical index for assessment of long-term damage in juvenile idiopathic arthritis
    Stefania Viola
    , IRCCS G. Gaslini, Genoa, Italy
    Arthritis Rheum 52:2092-102. 2005
    ....
  41. ncbi Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial
    Nicolino Ruperto
    IRCCS G Gaslini, PRINTO, Genoa, Italy
    Lancet 372:383-91. 2008
    ..We aimed to assess the safety and efficacy of abatacept, a selective T-cell costimulation modulator, in children with juvenile idiopathic arthritis who had failed previous treatments...
  42. ncbi Development and preliminary validation of a paediatric-targeted MRI scoring system for the assessment of disease activity and damage in juvenile idiopathic arthritis
    Clara Malattia
    Correspondence to Dr Clara Malattia, Pediatria II, IRCCS G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    Ann Rheum Dis 70:440-6. 2011
    ..To compare the paediatric MRI score with the adult-designed. Outcome Measures in Rheumatology Clinical Trials-Rheumatoid Arthritis MRI Score (RAMRIS), whose suitability for assessing growing joints was tested...
  43. ncbi Criteria to define response to therapy in paediatric rheumatic diseases
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II, Reumatologia, Pædiatric Rheumatology International Trials Organisation PRINTO, Genoa, Italy
    Eur J Clin Pharmacol 67:125-31. 2011
    ....
  44. ncbi Abatacept improves health-related quality of life, pain, sleep quality, and daily participation in subjects with juvenile idiopathic arthritis
    Nicolino Ruperto
    Universita di Genova, Genoa, Italy
    Arthritis Care Res (Hoboken) 62:1542-51. 2010
    ..To assess health-related quality of life (HRQOL) in abatacept-treated children/adolescents with juvenile idiopathic arthritis (JIA)...
  45. ncbi Magnetic resonance imaging, ultrasonography, and conventional radiography in the assessment of bone erosions in juvenile idiopathic arthritis
    Clara Malattia
    Istituto G Gaslini, Genoa, Italy
    Arthritis Rheum 59:1764-72. 2008
    ....
  46. ncbi The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis
    Nicolino Ruperto
    Paediatric Rheumatology International Trials Organisation, Genoa, Italy
    Arthritis Care Res (Hoboken) 62:1533-41. 2010
    ..To develop a provisional definition for the evaluation of response to therapy in juvenile dermatomyositis (DM) based on the Paediatric Rheumatology International Trials Organisation juvenile DM core set of variables...
  47. ncbi Development and testing of reduced joint counts in juvenile idiopathic arthritis
    Anna Bazso
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    J Rheumatol 36:183-90. 2009
    ..To develop and test reduced joint counts in children with juvenile idiopathic arthritis (JIA)...
  48. ncbi Agreement between multi-dimensional and renal-specific response criteria in patients with juvenile systemic lupus erythematosus and renal disease
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II, Reumatologia, Paediatric Rheumatology INternational Trials Organisation PRINTO, Genova, Italy
    Clin Exp Rheumatol 28:424-33. 2010
    ..To evaluate change over time and level of agreement of renal-specific and multi-dimensional measures in juvenile systemic lupus erythematosus (SLE) with renal disease...
  49. ncbi Health-related quality of life of patients with juvenile dermatomyositis: results from the Pediatric Rheumatology International Trials Organisation multinational quality of life cohort study
    Maria Teresa Apaz
    Paediatric Rheumatology International Trials Organisation, Genoa, Italy
    Arthritis Rheum 61:509-17. 2009
    ..To investigate the health-related quality of life (HRQOL) change over time, as measured by the Child Health Questionnaire (CHQ), and its determinants in patients with active juvenile dermatomyositis (DM)...
  50. ncbi EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part I: Overall methodology and clinical characterisation
    Nicolino Ruperto
    Paediatric Rheumatology INternational Trials Organisation PRINTO, IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, EULAR Centre of Excellence in Rheumatology 2008 2013, Largo Gaslini, 5, Genova 16147, Italy
    Ann Rheum Dis 69:790-7. 2010
    ....
  51. ncbi Development and initial validation of a radiographic scoring system for the hip in juvenile idiopathic arthritis
    Marta Bertamino
    Universita degli Studi di Genova, Genova, Italy
    J Rheumatol 37:432-9. 2010
    ..To develop and validate a radiographic scoring system for the assessment of radiographic damage in the hip joint in patients with juvenile idiopathic arthritis (JIA)...
  52. ncbi Dynamic contrast-enhanced magnetic resonance imaging in the assessment of disease activity in patients with juvenile idiopathic arthritis
    Clara Malattia
    Pediatria II, IRCCS G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    Rheumatology (Oxford) 49:178-85. 2010
    ..To determine the capability and reliability of dynamic contrast-enhanced MRI (DCE-MRI) in the assessment of disease activity in juvenile idiopathic arthritis (JIA)...
  53. ncbi Consensus procedures and their role in pediatric rheumatology
    Nicolino Ruperto
    IRCCS G Gaslini, Pediatria II PRINTO, University of Genoa, Largo Gaslini, 5, 16147 Genova, Italy
    Curr Rheumatol Rep 10:142-6. 2008
    ....
  54. ncbi The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis
    Marco Gattorno
    G Gaslini Institute, Genoa, Italy
    Arthritis Rheum 58:1505-15. 2008
    ..To assess the clinical response to interleukin-1 (IL-1) blockade and in vitro IL-1beta and IL-18 secretion in patients with systemic-onset juvenile idiopathic arthritis (JIA)...
  55. ncbi A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis
    Nicolino Ruperto
    IRCCS, Istituto G Gaslini, Genoa, Italy
    Arthritis Rheum 56:3096-106. 2007
    ..To evaluate the safety and efficacy of infliximab in the treatment of juvenile rheumatoid arthritis (JRA)...
  56. ncbi The provisional Paediatric Rheumatology International Trials Organisation/American College of Rheumatology/European League Against Rheumatism Disease activity core set for the evaluation of response to therapy in juvenile dermatomyositis: a prospective va
    Nicolino Ruperto
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 59:4-13. 2008
    ..To validate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile dermatomyositis (DM)...
  57. ncbi Preliminary core sets of measures for disease activity and damage assessment in juvenile systemic lupus erythematosus and juvenile dermatomyositis
    Nicolino Ruperto
    IRCCS G Gasalini, Pediatria II, Genova, Italy
    Rheumatology (Oxford) 42:1452-9. 2003
    ..To identify preliminary core sets of outcome variables for disease activity and damage assessment in juvenile systemic lupus erythematosus (JSLE) and juvenile dermatomyositis (JDM)...
  58. ncbi The Pediatric Rheumatology International Trials Organization/American College of Rheumatology provisional criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the definition of improvement
    Nicolino Ruperto
    Pediatric Rheumatology International Trials Organization, IRCCS G Gaslini, Università di Genova Pediatria II Reumatologia, 5 Largo Gaslini, 16147 Genoa, Italy
    Arthritis Rheum 55:355-63. 2006
    ....
  59. ncbi The Pediatric Rheumatology International Trials Organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the disease activity core set
    Nicolino Ruperto
    Pediatric Rheumatology International Trials Organization PRINTO, IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, Largo Gaslini, Genoa, Italy
    Arthritis Rheum 52:2854-64. 2005
    ..To validate and promulgate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile systemic lupus erythematosus (SLE)...
  60. ncbi Combination therapy with methotrexate and cyclosporine A in juvenile idiopathic arthritis
    A Ravelli
    Pediatria II, IRCCS G. Gaslini, , Italy
    Clin Exp Rheumatol 20:569-72. 2002
    ..CONCLUSION: In our JIA patients who were refractory to MTX as a single second-line agent, the addition of CyA was associated with a significant clinical improvement in roughly half of the patients...
  61. ncbi Functional ability and physical and psychosocial well-being of hypermobile schoolchildren
    N Ruperto
    Dipartimento di Pediatria, , , Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    Clin Exp Rheumatol 22:495-8. 2004
    ..These results suggest that the physical functioning in everyday life and the general health status of hypermobile children are not impaired...
  62. ncbi Predictors of poor response to methotrexate in polyarticular-course juvenile idiopathic arthritis: analysis of the PRINTO methotrexate trial
    Iris Vilca
    IRCCS G Gaslini, Pediatria II, Reumatologia, PRINTO, Genova, Italy
    Ann Rheum Dis 69:1479-83. 2010
    ..To determine whether baseline demographic, clinical, articular and laboratory variables predict methotrexate (MTX) poor response in polyarticular-course juvenile idiopathic arthritis...
  63. ncbi Evaluation of 21-numbered circle and 10-centimeter horizontal line visual analog scales for physician and parent subjective ratings in juvenile idiopathic arthritis
    Giovanni Filocamo
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Rheumatol 37:1534-41. 2010
    ..To evaluate the measurement properties of 21-numbered circle visual analog scales (VAS) and traditional 10-cm horizontal line VAS for physician and parent subjective ratings in children with juvenile idiopathic arthritis (JIA)...
  64. ncbi Assessment of damage in juvenile-onset systemic lupus erythematosus: a multicenter cohort study
    Angelo Ravelli
    Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genoa, Italy
    Arthritis Rheum 49:501-7. 2003
    ..Damage was significantly more likely in patients who had experienced neuropsychiatric manifestations at diagnosis, had a longer disease duration, and had received more intravenous pulses of cyclophosphamide...
  65. ncbi Use of the Sharp and Larsen scoring methods in the assessment of radiographic progression in juvenile idiopathic arthritis
    Federica Rossi
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 55:717-23. 2006
    ..CONCLUSION: Our results demonstrate that the Sharp and Larsen scoring systems are potentially reliable and valid for assessment of radiographic progression in patients with polyarticular JIA...
  66. ncbi The Pediatric Rheumatology European Society/American College of Rheumatology/European League against Rheumatism provisional classification criteria for juvenile systemic sclerosis
    Francesco Zulian
    Dipartimento di Pediatria, University of Padua, Padua, Italy
    Arthritis Rheum 57:203-12. 2007
    ..To develop criteria for the classification of systemic sclerosis (SSc) in children (juvenile SSc)...
  67. ncbi Assessing current outcomes of juvenile idiopathic arthritis: a cross-sectional study in a tertiary center sample
    Nicoletta Solari
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 59:1571-9. 2008
    ....
  68. ncbi Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment
    A Ravelli
    Department of Pediatrics, Universita degli Studi di Genova, Genova, Italy
    Genes Immun 13:289-98. 2012
    ..There has been remarkable progress in the use of anti-pro-inflammatory cytokine therapy, particularly against interleukin-1, in the treatment of secondary forms of MAS, such as in sJIA...
  69. ncbi Physicians' and parents' ratings of inactive disease are frequently discordant in juvenile idiopathic arthritis
    Alessandro Consolaro
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Rheumatol 34:1773-6. 2007
    ..To investigate discrepancies between physicians' and parents' ratings of inactive disease in children with juvenile idiopathic arthritis (JIA) and the determinants of the discrepancy...
  70. ncbi Validation of the Childhood Health Assessment Questionnaire in active juvenile systemic lupus erythematosus
    Silvia Meiorin
    IRCCS G Gaslini, Pediatria II, Reumatologia and Paediatric Rheumatology International Trials Organisation, Universita di Genova, Largo Gaslini 5, Genoa, Italy
    Arthritis Rheum 59:1112-9. 2008
    ..To validate the Childhood Health Assessment Questionnaire (C-HAQ) as a measure of disability in patients with active juvenile systemic lupus erythematosus (SLE)...
  71. ncbi Achievement of a state of inactive disease at least once in the first 5 years predicts better outcome of patients with polyarticular juvenile idiopathic arthritis
    Alessandra Magnani
    Istituto G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    J Rheumatol 36:628-34. 2009
    ..To investigate whether the achievement of inactive disease in the first 5 years predicts a more favorable outcome of children with juvenile idiopathic arthritis (JIA)...
  72. ncbi Level of agreement between children, parents, and physicians in rating pain intensity in juvenile idiopathic arthritis
    Pablo Garcia-Munitis
    , Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, , Largo G. Gaslini 5, 16147 Genoa, Italy
    Arthritis Rheum 55:177-83. 2006
    ..The intensity of pain was the strongest determinant of discordance between children and other raters...
  73. ncbi Development and validation of a new short and simple measure of physical function for juvenile idiopathic arthritis
    Giovanni Filocamo
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 57:913-20. 2007
    ..To develop and validate a new short and simple measure of physical function in children with juvenile idiopathic arthritis (JIA)...
  74. ncbi Treatment of Takayasu's arteritis with tumor necrosis factor antagonists
    Giovanni Filocamo
    Pediatria II IRCCS G Gaslini e Dipartimento di Pediatria, Universita di Genova, Italy
    J Pediatr 153:432-4. 2008
    ..Two patients went into remission; in the other 2, the response was partial. Anti-tumor necrosis factor agents can have a role in the treatment of Takayasu's arteritis; further controlled studies are required...
  75. ncbi Macrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients
    Alessandro Parodi
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genoa, Italy
    Arthritis Rheum 60:3388-99. 2009
    ..To describe the clinical and laboratory features of macrophage activation syndrome as a complication of juvenile systemic lupus erythematosus (SLE)...
  76. ncbi A proposal for a pediatric version of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index based on the analysis of 1,015 patients with juvenile-onset systemic lupus erythematosus
    Raul Gutiérrez-Suárez
    IRCCS G Gaslini, Genoa, Italy
    Arthritis Rheum 54:2989-96. 2006
    ....
  77. ncbi Outcome and predicting factors of single and multiple intra-articular corticosteroid injections in children with juvenile idiopathic arthritis
    Stefano Lanni
    Department of Pediatrics, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Policlinico San Matteo, Pavia, Italy
    Rheumatology (Oxford) 50:1627-34. 2011
    ..To investigate the efficacy of IA CS (IAC) therapy in single and multiple joints in children with JIA and to seek for predictors of synovitis flare...
  78. ncbi A new approach to clinical care of juvenile idiopathic arthritis: the Juvenile Arthritis Multidimensional Assessment Report
    Giovanni Filocamo
    Pediatria II, Istituto G Gaslini, Largo G Gaslini 5, Genoa, Italy
    J Rheumatol 38:938-53. 2011
    ..To develop and test a new multidimensional questionnaire for assessment of children with juvenile idiopathic arthritis (JIA) in standard clinical care...
  79. ncbi An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis
    Sergio Davì
    Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Rheumatol 38:764-8. 2011
    ..To identify candidate diagnostic criteria for macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (sJIA) using international consensus formation through a Delphi questionnaire survey...
  80. ncbi HRCT and pulmonary function tests in monitoring of lung involvement in juvenile systemic sclerosis
    Serena Panigada
    U O Pneumologia, IRCCS G Gaslini, Genova, Italy
    Pediatr Pulmonol 44:1226-34. 2009
    ..To investigate the role of high-resolution computed tomography (HRCT) and pulmonary function tests (PFTs) in staging pulmonary involvement in juvenile systemic sclerosis (JSS)...
  81. ncbi Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis
    Fabrizio De Benedetti
    IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy
    Arthritis Rheum 48:1398-407. 2003
    ....
  82. ncbi The time has come to include assessment of radiographic progression in juvenile idiopathic arthritis clinical trials
    Angelo Ravelli
    J Rheumatol 35:553-7. 2008
  83. ncbi Preliminary validation of clinical remission criteria using the OMERACT filter for select categories of juvenile idiopathic arthritis
    Carol A Wallace
    Division of Immunology, Rheumatology, and Infectious Disease, Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
    J Rheumatol 33:789-95. 2006
    ..To begin the validation process of the preliminary criteria for inactive disease (ID), clinical remission on medication (CRM), and clinical remission off medication (CR) in children with select forms of juvenile idiopathic arthritis (JIA)...
  84. ncbi Patterns of clinical remission in select categories of juvenile idiopathic arthritis
    Carol A Wallace
    Children s Hospital and Regional Medical Center, and University of Washington School of Medicine, 4800 Sand Point Way NE, Seattle, WA 98105, USA
    Arthritis Rheum 52:3554-62. 2005
    ....
  85. ncbi Prognostic factors for radiographic progression, radiographic damage, and disability in juvenile idiopathic arthritis
    Silvia Magni-Manzoni
    Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo, Pavia, Italy
    Arthritis Rheum 48:3509-17. 2003
    ..CONCLUSION: We identified the prognostic factors for poorer outcome in polyarticular-course JIA. The changes in the early Poznanski score can be used to predict long-term joint damage and physical disability...
  86. ncbi Reply to letter by Isenberg and Gordon commenting on the Pediatric Rheumatology International Trials Organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus
    Nicolino Ruperto
    Arthritis Rheum 54:3723-4. 2006
  87. ncbi Macrophage migration inhibitory factor in patients with juvenile idiopathic arthritis
    Cristina Meazza
    University of Pavia, IRCCS Policlinico San Matteo, Italy
    Arthritis Rheum 46:232-7. 2002
    ..CONCLUSION: MIF appears to be a relevant cytokine in the pathogenesis of JIA, particularly in systemic-onset JIA...
  88. ncbi Self epitopes shared between human skeletal myosin and Streptococcus pyogenes M5 protein are targets of immune responses in active juvenile dermatomyositis
    Margherita Massa
    IRCCS Policlinico San Matteo, Pavia, Italy
    Arthritis Rheum 46:3015-25. 2002
    ..CONCLUSION: These findings represent the first identification of a self epitope in juvenile DM, providing a potential candidate for antigen-specific immune therapy...
  89. ncbi Systemic sclerosis in childhood: clinical and immunologic features of 153 patients in an international database
    Giorgia Martini
    University of Padua, Padua, Italy
    Arthritis Rheum 54:3971-8. 2006
    ..Juvenile SSc appears to be less severe than in adults because children have less internal organ involvement, a less specific autoantibody profile, and a better long-term outcome...
  90. ncbi Positive family history of psoriasis does not affect the clinical expression and course of juvenile idiopathic arthritis patients with oligoarthritis
    Elena Tsitsami
    IRCCS Policlinico S. Matteo, , Pavia, Italy
    Arthritis Rheum 49:488-93. 2003
    ..These findings argue against the exclusion of the former patients from the oligoarthritis category of JIA...