Anna Corcione

Summary

Affiliation: G. Gaslini Institute
Country: Italy

Publications

  1. doi request reprint CX3CL1/fractalkine is a novel regulator of normal and malignant human B cell function
    Anna Corcione
    Laboratory of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Leukoc Biol 92:51-8. 2012
  2. pmc CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes
    Anna Corcione
    Laboratory of Oncology, IRCCS G Gaslini, Genova, Italy
    PLoS ONE 4:e8485. 2009
  3. pmc Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis
    Anna Corcione
    Laboratory of Oncology, IRCCS G Gaslini, Largo G Gaslini 5, Genoa, 16148, Italy
    Arthritis Res Ther 11:R150. 2009
  4. ncbi request reprint Human mesenchymal stem cells modulate B-cell functions
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
    Blood 107:367-72. 2006
  5. ncbi request reprint Chemokine receptor expression and function in childhood acute lymphoblastic leukemia of B-lineage
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
    Leuk Res 30:365-72. 2006
  6. pmc Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis
    Anna Corcione
    Laboratory of Oncology, Scientific Direction, G Gaslini Institute, 16148 Genoa, Italy
    Proc Natl Acad Sci U S A 101:11064-9. 2004
  7. ncbi request reprint CCL19 and CXCL12 trigger in vitro chemotaxis of human mantle cell lymphoma B cells
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genoa, Italy
    Clin Cancer Res 10:964-71. 2004
  8. ncbi request reprint Chemotaxis of human tonsil B lymphocytes to CC chemokine receptor (CCR) 1, CCR2 and CCR4 ligands is restricted to non-germinal center cells
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
    Int Immunol 14:883-92. 2002
  9. ncbi request reprint CCL3 (MIP-1alpha) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2
    Luciano Ottonello
    Laboratory of Phagocyte Physiopathology and Inflammation, Department of Internal Medicine, University of Genoa, G Gaslini Institute, Genoa, Italy
    Cell Signal 17:355-63. 2005
  10. ncbi request reprint B-cell differentiation in the CNS of patients with multiple sclerosis
    Anna Corcione
    Laboratory of Oncology, Department of Experimental and Laboratory Medicine, Scientific G Gaslini Institute, Genoa, Italy
    Autoimmun Rev 4:549-54. 2005

Detail Information

Publications15

  1. doi request reprint CX3CL1/fractalkine is a novel regulator of normal and malignant human B cell function
    Anna Corcione
    Laboratory of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico G Gaslini, Genova, Italy
    J Leukoc Biol 92:51-8. 2012
    ..Taken together, our data delineate a novel role for the CX(3)CL1/CX(3)CR1 complex in the biology of normal B cells and B-CLL cells. These topics are the subject of this review article...
  2. pmc CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes
    Anna Corcione
    Laboratory of Oncology, IRCCS G Gaslini, Genova, Italy
    PLoS ONE 4:e8485. 2009
    ....
  3. pmc Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis
    Anna Corcione
    Laboratory of Oncology, IRCCS G Gaslini, Largo G Gaslini 5, Genoa, 16148, Italy
    Arthritis Res Ther 11:R150. 2009
    ..Here, we have characterized synovial fluid and tissue B-cell subsets in patients with oligoarticular juvenile idiopathic arthritis (JIA), an issue not addressed before in detail...
  4. ncbi request reprint Human mesenchymal stem cells modulate B-cell functions
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
    Blood 107:367-72. 2006
    ..These results further support the potential therapeutic use of hMSCs in immune-mediated disorders, including those in which B cells play a major role...
  5. ncbi request reprint Chemokine receptor expression and function in childhood acute lymphoblastic leukemia of B-lineage
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
    Leuk Res 30:365-72. 2006
    ..Freshly isolated CCR7(+) early pre-B-ALL cells migrated to CCL19, whereas CCR7(+) pro-B- and pre-B-ALL cells were attracted by CCL19 only following culture with soluble recombinant CD40 ligand...
  6. pmc Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis
    Anna Corcione
    Laboratory of Oncology, Scientific Direction, G Gaslini Institute, 16148 Genoa, Italy
    Proc Natl Acad Sci U S A 101:11064-9. 2004
    ..The presence of lymphotoxin-alpha, CXCL12, and CXCL13 in the CNS may provide favorable microenvironmental conditions for these events...
  7. ncbi request reprint CCL19 and CXCL12 trigger in vitro chemotaxis of human mantle cell lymphoma B cells
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genoa, Italy
    Clin Cancer Res 10:964-71. 2004
    ..Information on these issues may allow us to identify novel mechanisms of chemokine-driven tumor cell migration...
  8. ncbi request reprint Chemotaxis of human tonsil B lymphocytes to CC chemokine receptor (CCR) 1, CCR2 and CCR4 ligands is restricted to non-germinal center cells
    Anna Corcione
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
    Int Immunol 14:883-92. 2002
    ..CCR1, CCR2 and CCR4 were detected by flow cytometry on non-GC (i.e. naive and memory) B cells, whereas they were absent (CCR1 and CCR2) or poorly expressed (CCR4) on GC B cells...
  9. ncbi request reprint CCL3 (MIP-1alpha) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2
    Luciano Ottonello
    Laboratory of Phagocyte Physiopathology and Inflammation, Department of Internal Medicine, University of Genoa, G Gaslini Institute, Genoa, Italy
    Cell Signal 17:355-63. 2005
    ..This suggests that by activating ERK-1, GM-CSF renders neutrophils rapidly responsive to CCL3 stimulation throughout CCR5 which is constitutively expressed on the cell surface...
  10. ncbi request reprint B-cell differentiation in the CNS of patients with multiple sclerosis
    Anna Corcione
    Laboratory of Oncology, Department of Experimental and Laboratory Medicine, Scientific G Gaslini Institute, Genoa, Italy
    Autoimmun Rev 4:549-54. 2005
    ..Thus, B cells are likely to expand and mature inside the CNS, giving rise to ASC, which may play an effector role in the pathogenesis of MS...
  11. pmc Changes in cytokine profile pre- and post-immunosuppression in acquired aplastic anemia
    Carlo Dufour
    Haematology Unit, G Gaslini Children s Hospital, Genoa, Italy
    Haematologica 94:1743-7. 2009
    ....
  12. ncbi request reprint Human Fanconi A cells are susceptible to TRAIL-induced apoptosis
    Simona Pigullo
    Haematology Unit, Department of Paediatric Haemato Oncology, G Gaslini Children s Hospital, Genoa, Italy
    Br J Haematol 136:315-8. 2007
    ..This effect involved poly(ADP-ribose) polymerase-1 cleavage and caspase-8 activation...
  13. ncbi request reprint TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro
    Carlo Dufour
    Hematology Unit, Department of Pediatric Hematology Oncology, G Gaslini Children s Hospital, Largo G Gaslini 5, 16147 Genoa, Italy
    Blood 102:2053-9. 2003
    ..This indicates that FA subjects have a marrow TNF-alpha activity that inhibits erythropoiesis in vitro. TNF-alpha has a relevant role in the pathogenesis of erythroid failure in FA patients...
  14. ncbi request reprint The interleukin-12 and interleukin-12 receptor system in normal and transformed human B lymphocytes
    Irma Airoldi
    Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genoa, Italy
    Haematologica 87:434-42. 2002
    ..IL-12 also activates human B-cells through the IL-12 receptor (IL-12R) complex. Here we review the expression and function of IL-12 and IL-12R in human B-cells and in their malignant counterparts...
  15. ncbi request reprint Mechanisms of the adaptive immune response inside the central nervous system during inflammatory and autoimmune diseases
    Enrico Pedemonte
    Neuroimmunology Unit, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy
    Pharmacol Ther 111:555-66. 2006
    ....