Research Topics
| A FregaSummaryCountry: Italy Publications
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Publications
The prognostic significance of acetowhitening of the vulva and HPV-DNA test. A multicentre studyA Frega
Department of Obstetrics and Gynecology, 2nd Chair, University La Sapienza of Rome, Rome, Italy
Cancer Lett 172:133-5. 2001..001). Our findings suggest that independently from HPV type and in the absence of cofactors, there is a statistically significant spontaneous remission of these areas...- Vaginal intraepithelial neoplasia: a therapeutical dilemmaAntonio Frega
Department of Gynecological, Obstetric and Urological Sciences, Sant Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035 1039, 00189 Rome, Italy
Anticancer Res 33:29-38. 2013..The need to maintain the integrity of reproductive capacity has determined the transition from radical therapies to conservative ones, according to the different patients' characteristics... - Clinical management and follow-up of squamous intraepithelial cervical lesions during pregnancy and postpartumAntonio Frega
Department of Gynecology, Perinatology and Childhealth, University La Sapienza Rome, Italy
Anticancer Res 27:2743-6. 2007..The objective of the study was to assess proper management of squamous intraepithelial lesion (SIL) during and after pregnancy, to assess regression, persistence and risk of progression and the predictive role of HPV tests... - Prevalence of acetowhite areas in male partners of women affected by HPV and squamous intra-epithelial lesions (SIL) and their prognostic significance. A multicenter studyAntonio Frega
Department of Gynecology, Perinatology and Child Health, University of Rome La Sapienza, Policlinic Umberto I, Viale Regina Elena 324, Rome, Italy
Anticancer Res 26:3171-4. 2006..The prognostic significance of acetowhite areas, of male partners of women affected by HPV and preneoplastic lesions, was evaluated... - Follow-up of high-grade squamous intra-epithelial lesions (H-SIls) in human immunodeficiency virus (HIV)-positive and human papillomavirus (HPV)-positive women. analysis of risk factorsAntonio Frega
Department of Gynecology, Perinatology and Child Health, University of Rome La Sapienza, Rome, Italy
Anticancer Res 26:3167-70. 2006..Human immunodeficiency virus (HIV)-positive women are at high risk of co-infection from human papillomavirus (HPV) and of developing squamous intraepithelial lesions of the cervix... - Imiquimod treatment of vulvitis circumscripta plasmacellularisA Frega
Department of Gynecology, Perinatology and Child Health, University La Sapienza, Rome, Italy
Int J Gynaecol Obstet 95:161-2. 2006 - Oral contraceptives and clinical recurrence of human papillomavirus lesions and cervical intraepithelial neoplasia following treatmentAntonio Frega
Department of Gynecology, Perinatology and Child Health, University La Sapienza, Rome, Italy
Int J Gynaecol Obstet 100:175-8. 2008..To evaluate the effect of oral contraceptive use on the recurrence rate of human papillomavirus (HPV) lesions and cervical intraepithelial neoplasia (CIN) following ablative or excisional procedures in a long-term follow-up... - Young women, cervical intraepithelial neoplasia and human papillomavirus: risk factors for persistence and recurrenceAntonio Frega
Department of Gynaecology, Perinatology and Childhealth, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
Cancer Lett 196:127-34. 2003..Because the small sample of our study group, further analyses were required... - Verrucous carcinoma of the cervix: detection of carcinogenetic human papillomavirus types and their role during follow-upAntonio Frega
Department of Gynecology, Perinatology and Childhealth, University Sapienza, Rome, Italy
Anticancer Res 27:4491-4. 2007..The aim of this study was to evaluate the presence of HPV in verrucous carcinomas of the cervix and to investigate the persistence and the role of high risk HPV types in follow-up... - Human papillomavirus in virgins and behaviour at riskAntonio Frega
Department of Gynecology Perinatology and Childcare, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
Cancer Lett 194:21-4. 2003..This can be due to vertical transmission, fomities and skin-to-skin contact. Many other hypothesis can be proposed to explain HPV genital infection, however, further studies are required... - Giant condyloma acuminatum or buschke-Lowenstein tumor: review of the literature and report of three cases treated by CO2 laser surgery. A long-term follow-upAntonio Frega
II Department of Obstetrics and Gynaecology, II Faculty, University of Rome La Sapienza, Rome, Italy
Anticancer Res 22:1201-4. 2002..It is advisable to treat it early. After a review of the literature, three cases of giant condyloma acuminatum, treated by combined CO2 Laser surgery excision-vaporization and which underwent a long-term follow-up are described... - The re-infection rate of high-risk HPV and the recurrence rate of vulvar intraepithelial neoplasia (VIN) usual type after surgical treatmentAntonio Frega
Department of Woman s Health and Territorial Medicine, Faculty of Medicine and Psychology Sapienza University of Rome, Rome, Italy
Med Sci Monit 17:CR532-5. 2011..VIN usual type appears to be related to the HPV's oncogenic types. The aim of this prospective multicenter study was to evaluate the re-infection rate of high-risk HPV and the recurrence rate of VIN usual type after surgical treatment... - Prediction of persistent vaginal intraepithelial neoplasia in previously hysterectomized women by high-risk HPV DNA detectionA Frega
Department of Gynecology, Perinatology and Child Health, Faculty of Medicine, University La Sapienza, Rome, Italy
Cancer Lett 249:235-41. 2007.... - Prognostic implication of high risk human papillomavirus E6 and E7 mRNA in patients with intraepithelial lesions of the cervix in relationship to ageA Frega
Department of Woman s Health and Territorial Medicine, Sant Andrea Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy
Int J Immunopathol Pharmacol 24:461-70. 2011.... - Regression rate of clinical HPV infection of the lower genital tract during pregnancy after laser CO2 surgeryA Frega
Department of Gynecology, Perinatology and Childhealth, University La Sapienza of Rome, Italy
Clin Exp Obstet Gynecol 33:93-5. 2006..Rarity of respiratory papillomatosis makes conclusions inconsistent for the prevention of vertical infection... - Improvement of uterine artery Doppler velocimetry indices after metroplasty in arcuate uteriS Pace
Department of Gynecology, Perinatology and Child Health, University La Sapienza, Rome, Italy
Eur J Obstet Gynecol Reprod Biol 131:81-4. 2007..Our study aimed to evaluate the effect of metroplasty performed in arcuate uteri on uterine artery Doppler velocimetry... - Fertility-sparing treatment of endometrial cancer precursors among young women: a reproductive point of viewE Ricciardi
Department of Obstetrics, Sapienza University of Rome, Rome, Italy
Eur Rev Med Pharmacol Sci 16:1934-7. 2012..An emerging issue among younger women affected is the possibility of a fertility-sparing treatment with progestative therapy and close follow-up... - HPV and pregnancy: diagnostic methods, transmission and evolutionS Arena
Dipartimento di Scienze Ginecologiche, Ostetriche e Pediatriche, Universita degli Studi, Perugia, Italy
Minerva Ginecol 54:225-37. 2002..A number of Authors report an initial presence of HPV in newborns which often disappears within 6 months after birth... - Pregnancy and condyloma. Evaluation about therapeutic effectiveness of laser CO2 on 115 pregnant womenS Arena
Dipartimento di Scienze Ginecologiche, Ostetriche e Pediatriche, Universita degli Studi, Perugia, Italy
Minerva Ginecol 53:389-96. 2001..The aim of this study was to evaluate the therapeutic efficacy of laser-vaporization in genital condylomata during pregnancy... - Imiquimod 5% cream versus cold knife excision for treatment of VIN 2/3: a five-year follow-upA Frega
Department of Gynecological, Obstetric and Urological Sciences, Sant Andrea Hospital, Sapienza University of Rome, Rome, Italy
Eur Rev Med Pharmacol Sci 17:936-40. 2013..Vulvar intraepithelial neoplasia (VIN) is a premalingnant condition. For long time, surgery was considered the first-line therapy in the treatment of high grade VIN. Imiquimod was recently introduced as an alternative to surgery... - Evaluation of E6 and E7 mRNA expression in HPV DNA positive breast cancerA Frega
Department of Woman s Health and Territorial Medicine, Sant Andrea Hospital, Faculty of Medicine and Psychology, Italy
Eur J Gynaecol Oncol 33:164-7. 2012..The role of the virus in breast oncogenesis is still unclear, since our analysis failed in demonstrating the expression of viral E6 and E7 in positive HPV positive breast tumor tissues... - Endoscopic treatment of intrauterine adhesionsS Pace
2nd Clinic of Obstetrics and Gynaecology, University La Sapienza, Rome, Italy
Clin Exp Obstet Gynecol 30:26-8. 2003..CONCLUSION: Good anatomic results are obtained after hysteroscopic treatment of intrauterine adhesions, and pregnancy rates vary from 28.7 to 53.6%... - Determination of cervicovaginal microorganisms in women with abnormal cervical cytology: the role of Ureaplasma urealyticumA Lukic
Department of Gynecologic Sciences, Perinatology and Puericulture, Second Faculty of Medicine and Surgery, La Sapienza University of Studies of Rome, Sant Andrea Hospital, Rome, Italy
Anticancer Res 26:4843-9. 2006.... - Vulvar Paget's disease: review of the literature, considerations about histogenetic hypothesis and surgical approachesA Tinari
Department of Gynaecology, Perinatology and Child Care, University of Rome, La Sapienza, Italy
Eur J Gynaecol Oncol 23:551-2. 2002..It predominantly is an intraepithelial lesion, but has the potential for dermal invasion and on occasion has been associated with an underlying adenocarcinoma...