Valentina Franco

Summary

Country: Italy

Publications

  1. doi request reprint Novel treatment options for epilepsy: focus on perampanel
    V Franco
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy
    Pharmacol Res 70:35-40. 2013
  2. doi request reprint Changes in lamotrigine pharmacokinetics during pregnancy and the puerperium
    Valentina Franco
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Ther Drug Monit 30:544-7. 2008
  3. ncbi request reprint A novel enantioselective microassay for the high-performance liquid chromatography determination of oxcarbazepine and its active metabolite monohydroxycarbazepine in human plasma
    Iolanda Mazzucchelli
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Ther Drug Monit 29:319-24. 2007
  4. doi request reprint Development and validation of an HPLC-UV detection assay for the determination of rufinamide in human plasma and saliva
    Iolanda Mazzucchelli
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy
    Anal Bioanal Chem 401:1013-21. 2011
  5. doi request reprint Characteristics of a large population of patients with refractory epilepsy attending tertiary referral centers in Italy
    Veriano Alexandre
    Institute of Neurology IRCCS C Mondino Foundation, Pavia, Italy
    Epilepsia 51:921-5. 2010
  6. ncbi request reprint Stereoselective determination of vigabatrin enantiomers in human plasma by high performance liquid chromatography using UV detection
    Valentina Franco
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Chromatogr B Analyt Technol Biomed Life Sci 854:63-7. 2007

Collaborators

Detail Information

Publications6

  1. doi request reprint Novel treatment options for epilepsy: focus on perampanel
    V Franco
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy
    Pharmacol Res 70:35-40. 2013
    ..Based on these data, perampanel offers a valuable option in the add-on treatment of partial-onset and secondarily generalized seizures...
  2. doi request reprint Changes in lamotrigine pharmacokinetics during pregnancy and the puerperium
    Valentina Franco
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Ther Drug Monit 30:544-7. 2008
    ....
  3. ncbi request reprint A novel enantioselective microassay for the high-performance liquid chromatography determination of oxcarbazepine and its active metabolite monohydroxycarbazepine in human plasma
    Iolanda Mazzucchelli
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    Ther Drug Monit 29:319-24. 2007
    ..However, because the two enantiomers of monohydroxycarbazepine exhibit similar pharmacologic activity, nonenantioselective assays are likely to be more cost-effective for therapeutic drug monitoring purposes...
  4. doi request reprint Development and validation of an HPLC-UV detection assay for the determination of rufinamide in human plasma and saliva
    Iolanda Mazzucchelli
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy
    Anal Bioanal Chem 401:1013-21. 2011
    ..25-20.0 μg ml(-1), with a limit of quantification at 0.25 μg ml(-1). Precision and accuracy are within current acceptability standards. The assay is suitable for pharmacokinetic studies in humans and for therapeutic drug monitoring...
  5. doi request reprint Characteristics of a large population of patients with refractory epilepsy attending tertiary referral centers in Italy
    Veriano Alexandre
    Institute of Neurology IRCCS C Mondino Foundation, Pavia, Italy
    Epilepsia 51:921-5. 2010
    ..2%) in adults, and disorders of cortical development (14.7%) and nonprogressive encephalopathies (6.8%) in children. More than three-fourths of subjects in both age groups were on antiepileptic drug (AED) polytherapy...
  6. ncbi request reprint Stereoselective determination of vigabatrin enantiomers in human plasma by high performance liquid chromatography using UV detection
    Valentina Franco
    Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
    J Chromatogr B Analyt Technol Biomed Life Sci 854:63-7. 2007
    ..999) over the range of 0.5-40 microg/mL for each enantiomer, with a limit of quantification of 0.5 microg/mL for both analytes. The assay is suitable for therapeutic drug monitoring and for single-dose pharmacokinetic studies in man...