Paola Francalanci

Summary

Country: Italy

Publications

  1. pmc Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma
    Caecilia Hc Sukowati
    Centro Studi Fegato, Fondazione Italiana Fegato, Bld Q AREA Science Park Basovizza, Trieste, Italy
    BMC Gastroenterol 12:160. 2012
  2. ncbi Z and Mmalton-1-antitrypsin deficiency-associated hepatocellular carcinoma: a genetic study
    Paola Francalanci
    Department of Pathology, Bambino Gesu Children s Hospital, Rome, Italy
    Liver Int 29:1593-6. 2009
  3. ncbi CD44-v6 expression in smooth muscle cells in the postnatal remodeling process of ductus arteriosus
    Paola Francalanci
    Department of Pathology, Bambino Gesu Children s Hospital, Rome, Italy
    Am J Cardiol 97:1056-9. 2006
  4. doi Eosinophilic esophagitis and Barrett's esophagus: an occasional association or an overlap disease? Esophageal 'double trouble' in two children
    Paola Francalanci
    Department of Pathology, Children s Hospital Bambino Gesu, Rome, Italy
    Digestion 77:16-9. 2008
  5. ncbi Malignant pancreatic endocrine tumor in a child with tuberous sclerosis
    Paola Francalanci
    Department of Pathology, Children s Hospital Bambino Gesu, Piazza Sant Onofrio 4, Rome, Italy
    Am J Surg Pathol 27:1386-9. 2003
  6. ncbi Expression of the lipogenic enzyme fatty acid synthase (FAS) as a predictor of poor outcome in nephroblastoma: an interinstitutional study
    Francesca Diomedi Camassei
    Department of Pathology, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy
    Med Pediatr Oncol 40:302-8. 2003
  7. ncbi Pulmonary blastomas of childhood: histologic, immunohistochemical, ultrastructural aspects and therapeutic considerations
    Renata Boldrini
    Department of Pathology, Bambino Gesu Pediatric Hospital, IRCCS, Rome, Italy
    Ultrastruct Pathol 29:493-501. 2005
  8. doi Tyrosinemia type 1: metastatic hepatoblastoma with a favorable outcome
    Valerio Nobili
    Division of Metabolism, Bambino Gesu Children s Hospital, Rome, Italy
    Pediatrics 126:e235-8. 2010
  9. doi Two novel mutations in African and Asian children with progressive familial intrahepatic cholestasis type 3
    Isabella Giovannoni
    Dep Pathology, Children s Hospital Bambino Gesu, Rome, Italy
    Dig Liver Dis 43:567-70. 2011
  10. ncbi Severe liver disease in early childhood due to fibrinogen storage and de novo gamma375Arg-->Trp gene mutation
    Paola Francalanci
    Department of Pathology, Children s Hospital Bambino Gesu, Rome, Italy
    J Pediatr 148:396-8. 2006

Collaborators

Detail Information

Publications23

  1. pmc Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma
    Caecilia Hc Sukowati
    Centro Studi Fegato, Fondazione Italiana Fegato, Bld Q AREA Science Park Basovizza, Trieste, Italy
    BMC Gastroenterol 12:160. 2012
    ..Since data on ABCG2 expression in liver malignances are scanty, here we report the expression of ABCG2 in adult human hepatocellular carcinoma (HCC) in both in vivo and in vitro models with different degree of malignancy...
  2. ncbi Z and Mmalton-1-antitrypsin deficiency-associated hepatocellular carcinoma: a genetic study
    Paola Francalanci
    Department of Pathology, Bambino Gesu Children s Hospital, Rome, Italy
    Liver Int 29:1593-6. 2009
    ..It is noteworthy that hepatocellular carcinoma (HCC) arises specifically from the AAT-negative areas but the reason for this remains unclear...
  3. ncbi CD44-v6 expression in smooth muscle cells in the postnatal remodeling process of ductus arteriosus
    Paola Francalanci
    Department of Pathology, Bambino Gesu Children s Hospital, Rome, Italy
    Am J Cardiol 97:1056-9. 2006
    ..In conclusion, the present data provide evidence that closure of DA involves synthetic SMCs highly positive for CD44-v6, and patent or closed DAs are populated by CD44-v6-negative SMCs...
  4. doi Eosinophilic esophagitis and Barrett's esophagus: an occasional association or an overlap disease? Esophageal 'double trouble' in two children
    Paola Francalanci
    Department of Pathology, Children s Hospital Bambino Gesu, Rome, Italy
    Digestion 77:16-9. 2008
    ..Barrett's esophagus (BE) is due to chronic gastroesophageal reflux. The pathological consequence is the replacement of normal stratified squamous epithelium by columnar mucosa with goblet cells...
  5. ncbi Malignant pancreatic endocrine tumor in a child with tuberous sclerosis
    Paola Francalanci
    Department of Pathology, Children s Hospital Bambino Gesu, Piazza Sant Onofrio 4, Rome, Italy
    Am J Surg Pathol 27:1386-9. 2003
    ..These findings suggest a role for tuberin, the TSC2 gene product, in the pathogenesis of malignant pancreatic endocrine tumor...
  6. ncbi Expression of the lipogenic enzyme fatty acid synthase (FAS) as a predictor of poor outcome in nephroblastoma: an interinstitutional study
    Francesca Diomedi Camassei
    Department of Pathology, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy
    Med Pediatr Oncol 40:302-8. 2003
    ..Correlation of elevated levels of the lipogenic enzyme fatty acid synthase (FAS) with aggressiveness of some cancers has drawn attention to this enzyme as a possible marker of poor prognosis...
  7. ncbi Pulmonary blastomas of childhood: histologic, immunohistochemical, ultrastructural aspects and therapeutic considerations
    Renata Boldrini
    Department of Pathology, Bambino Gesu Pediatric Hospital, IRCCS, Rome, Italy
    Ultrastruct Pathol 29:493-501. 2005
    ..The expression of the transmembrane tyrosin kinase receptor c-kit in all the solid cases of this series leads the authors to hypothesize new possible therapeutic implications for these tumors...
  8. doi Tyrosinemia type 1: metastatic hepatoblastoma with a favorable outcome
    Valerio Nobili
    Division of Metabolism, Bambino Gesu Children s Hospital, Rome, Italy
    Pediatrics 126:e235-8. 2010
    ..We encourage clinicians to perform more accurate evaluation of liver histology, because a neoplastic mass in a child with tyrosinemia type 1 is not the same as HCC...
  9. doi Two novel mutations in African and Asian children with progressive familial intrahepatic cholestasis type 3
    Isabella Giovannoni
    Dep Pathology, Children s Hospital Bambino Gesu, Rome, Italy
    Dig Liver Dis 43:567-70. 2011
    ..Defects in ABCB4 have been found to cause progressive familial intrahepatic cholestasis type 3. Liver histology is important, but not specific, for diagnosis. Genotyping is conclusive...
  10. ncbi Severe liver disease in early childhood due to fibrinogen storage and de novo gamma375Arg-->Trp gene mutation
    Paola Francalanci
    Department of Pathology, Children s Hospital Bambino Gesu, Rome, Italy
    J Pediatr 148:396-8. 2006
    ..Fibrinogen gene analysis revealed a de novo Aguadilla (c.1201C>T; p.Arg375Trp) mutation. This mutation should be considered in childhood hypofibrinogenemia associated with chronic liver disease...
  11. ncbi Malignant pheochromocytoma in a 16-year-old patient with neurofibromatosis type 1
    Isabella Giovannoni
    1 Department of Pathology, Children s Hospital Bambino Gesu, IRCCS Rome, Italy
    Pediatr Dev Pathol 17:126-9. 2014
    ..On the other hand, since 30% of PHEOs had germline mutations and, more rarely, somatic mutations, patients with PHEO should be investigated for associated genetic syndromes...
  12. doi Bile salt export pump deficiency: A de novo mutation in a child compound heterozygous for ABCB11. Laboratory investigation to study pathogenic role and transmission of two novel ABCB11 mutations
    Paola Francalanci
    Department of Pathology Liver Unit Research Laboratories, Bambino Gesu Children s Hospital, IRCCS, Rome, Italy
    Hepatol Res 43:315-9. 2013
    ..This case stresses that clinical PFIC with an attenuated rather than absent BSEP immunostaining can still be due to ABCB11 mutations presumably encoding a functionally deficient protein...
  13. ncbi Paternal isodisomy of chromosome 2 in a child with bile salt export pump deficiency
    Isabella Giovannoni
    Units of Pathology Molecular Medicine and Neurosciences Hepatic Surgery, Children s Hospital Bambino Gesu, Rome Unit of Pathology, Molinette Hospital, Turin IRCCS Fondazione Stella Maris, Pisa, Italy
    Hepatol Res 42:327-31. 2012
    ..Recognizing isodisomic transmission may have a significant impact on genetic counseling helping to define the risk of recurrence in subsequent pregnancies...
  14. pmc Genotype-phenotype relationship in human ATP6i-dependent autosomal recessive osteopetrosis
    Anna Taranta
    Istituto Dermopatico dell Immacolata, Rome, Italy
    Am J Pathol 162:57-68. 2003
    ..Bone marrow transplantation was successful in all patients, and posttransplant osteoclasts showed rescue of a3 subunit immunoreactivity...
  15. ncbi Eosinophilic esophagitis: is it also a surgical disease?
    Francesca Rea
    Digestive Surgery and Endoscopy Unit, Pediatric Hospital and Research Institute Bambino Gesù IRCCS, Rome, 00165, Rome, Italy
    J Pediatr Surg 48:304-8. 2013
    ..An association between EoE and gastro-esophageal reflux disease (GERD) has not been well established...
  16. ncbi Cystic dysplasia of the rete testis: report of two cases and review of the literature
    Francesca Diomedi Camassei
    Department of Pathology, Bambino Gesu Children s Hospital Research Institute, Piazza S Onofrio 4, 00165 Rome, Italy
    Pediatr Dev Pathol 5:206-10. 2002
    ..Orchiectomy was performed in both patients, for extensive gonad involvement in the older boy and for suspected gonad torsion in the newborn patient...
  17. ncbi A new ABCB11 mutation in two Italian children with familial intrahepatic cholestasis
    Valerio Nobili
    Hepatology, IRCCS Bambino Gesù Hospital, Piazza S Onofrio, 4 00165, Rome, Italy
    J Gastroenterol 41:598-603. 2006
    ..Our findings are expected to facilitate detection of the molecular cause of PFIC in affected families...
  18. pmc Novel large-range mitochondrial DNA deletions and fatal multisystemic disorder with prominent hepatopathy
    Marzia Bianchi
    Unit of Molecular Medicine for Neuromuscular and Neurodegenerative Diseases, Bambino Gesu Children s Hospital, Rome, Italy
    Biochem Biophys Res Commun 415:300-4. 2011
    ..Our data further expand the array of deletions in the mitochondrial genomes in association with liver failure. Thus analysis of mtDNA should be considered in the diagnosis of childhood-onset hepatopathies...
  19. doi Autoimmune hepatitis type 2 following anti-papillomavirus vaccination in a 11-year-old girl
    Claudia Della Corte
    Unit of Liver Research, Department of Pathology, Bambino Gesu Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    Vaccine 29:4654-6. 2011
    ....
  20. doi Preemptive liver transplantation in a child with familial hypercholesterolemia
    Arianna Maiorana
    Metabolic Unit, Bambino Gesu Children Hospital, Rome, Italy
    Pediatr Transplant 15:E25-9. 2011
    ..Preemptive liver transplantation is a definitive cure of familial homozygous hypercholesterolemia and might be more effective if performed before development of vascular complications...
  21. doi Association of DiGeorge anomaly and caudal dysplasia sequence in a neonate born to a diabetic mother
    Maria L Dentici
    Department of Medical Genetics, Cardiology and Pathology, Bambino Gesu Pediatric Hospital, IRCCS, Rome, Italy
    Cardiol Young 23:14-7. 2013
    ..Infants with DiGeorge anomaly can display additional manifestations within the spectrum of caudal dysplasia sequence, including vertebral anomalies and renal agenesis...
  22. ncbi Cystitis glandularis in children
    Nicola Capozza
    Division of Paediatric Urology, Bambino Gesu Children s Hospital, Research Institute, Piazza S Onofrio, 4 00165, Rome, Italy
    BJU Int 95:411-3. 2005
    ..To assess the characteristics of cystitis glandularis in children...
  23. ncbi Nephroblastoma: multidrug-resistance P-glycoprotein expression in tumor cells and intratumoral capillary endothelial cells
    Francesca Diomedi Camassei
    Department of Pathology, Bambino Gesu Children s Hospital Research Institute, Rome, Italy
    Am J Clin Pathol 117:484-90. 2002
    ..Previous chemotherapy induced P-gp overexpression in tumor cells...