Research Topics
| R PerriSummaryAffiliation: Fondazione Santa Lucia Country: Italy Publications
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Detail Information
Publications
Amnestic mild cognitive impairment: difference of memory profile in subjects who converted or did not convert to Alzheimer's diseaseRoberta Perri
Foundation Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Santa Lucia, Italy
Neuropsychology 21:549-58. 2007..In this context of pervasive episodic memory impairment, tests assessing the free recall of verbal material following a delay interval demonstrated the greater sensitivity to memory deficits of a-MCI subjects who developed AD...
Alzheimer's disease and semantic deficits: a feature-listing studyRoberta Perri
Laboratory of Clinical and Behavioural Neurology, IRCCS Santa Lucia Foundation, Rome, Italy
Neuropsychology 26:652-63. 2012..Also, we investigated if feature correlation and level of feature occurrence in concept description (dominance) influence the resilience of concept features to degenerative damage...
Characterization of memory profile in subjects with amnestic mild cognitive impairmentR Perri
Fondazione IRCCS Santa Lucia, Rome, Italy
J Clin Exp Neuropsychol 27:1033-55. 2005....
Preclinical dementia: an Italian multicentre study on amnestic mild cognitive impairmentR Perri
Foundation IRCCS Santa Lucia, Rome, Italy
Dement Geriatr Cogn Disord 23:289-300. 2007..Different rates and cognitive predictors of conversion to dementia have been reported in subjects with different kinds of mild cognitive impairment (MCI)...
Intentional and automatic measures of specific-category effect in the semantic impairment of patients with Alzheimer's diseaseRoberta Perri
IRCCS Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy
Neuropsychologia 41:1509-22. 2003..The intentional/automatic dissociation of the semantic breakdown demonstrated by AD patients is discussed in relation to different theories regarding the organisation of semantic memory...
When the amnestic mild cognitive impairment disappears: characterisation of the memory profileRoberta Perri
Foundation IRCCS Santa Lucia, Rome, Italy
Cogn Behav Neurol 22:109-16. 2009..This is the first study investigating qualitative features of memory deficits in subjects affected by reversible MCI [reversible cognitive impairment (RCI)]...
Semantic priming for coordinate distant concepts in Alzheimer's disease patientsR Perri
Fondazione IRCCS Santa Lucia, Via Ardeatina, 00179 Rome, Italy
Neuropsychologia 49:839-47. 2011....
Alzheimer's disease and frontal variant of frontotemporal dementia-- a very brief battery for cognitive and behavioural distinctionRoberta Perri
Fondazione IRCCS Santa Lucia, Via Ardeatina, 306, 00179 Roma, Italy
J Neurol 252:1238-44. 2005..The present results emphasise the importance of rating both cognitive and behavioural clinical features of the two syndromes as objectively as possible to improve differential diagnostic accuracy...
White matter damage along the uncinate fasciculus contributes to cognitive decline in AD and DLBL Serra
Neuroimaging Laboratory, Santa Lucia Foundation, IRCCS, Via Ardeatina 306, 00179 Rome, Italy
Curr Alzheimer Res 9:326-33. 2012..Moreover, this UF damage seems to be driven by temporal involvement in AD, for which a prodromal stage (a-MCI) is defined...
Regional brain atrophy and functional disconnection across Alzheimer's disease evolutionT Gili
MARBILab, Enrico Fermi Centre, Rome, Italy
J Neurol Neurosurg Psychiatry 82:58-66. 2011..To assess the contribution of regional grey matter (GM) atrophy and functional disconnection in determining the level of cognitive decline in patients with Alzheimer's disease (AD) at different clinical stages...
Cognitive and behavioural predictors of progression rates in Alzheimer's diseaseI Buccione
I R C C S Fondazione Santa Lucia, Rome, Italy
Eur J Neurol 14:440-6. 2007..We found that cognitive decline was predicted by diffuse cognitive impairment and functional progression by visuospatial deficits. Psychotic symptoms predicted faster disease progression in both cognitive and functional dimensions...
Recollection and familiarity in amnesic mild cognitive impairmentLaura Serra
Neuroimaging Laboratory, Foundation IRCCS Santa Lucia, Rome, Italy
Neuropsychology 24:316-26. 2010..To investigate whether, in patients with amnesic mild cognitive impairment (a-MCI), recognition deficits are mainly due to a selective impairment of recollection rather than familiarity...
Left hand movements and right hemisphere activation in unilateral spatial neglect: a test of the interhemispheric imbalance hypothesisGuido Gainotti
Neuropsychology Service, Università Cattolica Policlinico Gemelli, Largo A Gemelli, 8 00168, Rome, Italy
Neuropsychologia 40:1350-5. 2002....
Loss of spatial learning in a patient with topographical disorientation in new environmentsP Turriziani
IRCCS Fondazione Santa Lucia, Rome, Italy Clinica Neurologica, , Via Ardeatina 306, 00179 Rome, Italy
J Neurol Neurosurg Psychiatry 74:61-9. 2003..The hippocampus appears to be involved in the acquisition of new topographical spatial knowledge...
Priming for novel between-word associations in patients with organic amnesiaG A Carlesimo
Clinica Neurologica, Universita Tor Vergata, Roma, Italy
J Int Neuropsychol Soc 11:566-73. 2005..These data support the hypothesis of similar impairment of new episodic and implicit learning in amnesic patients and suggest that the hippocampus is crucial for both kinds of new learning...
Remembering what but not where: independence of spatial and visual working memory in the human brainG A Carlesimo
IRCCS S Lucia, Roma, Italy
Cortex 37:519-34. 2001....
Deficient intentional access to semantic knowledge in patients with severe closed-head injuryR Perri
IRCCS S Lucia, Roma, Italy
Cortex 36:213-25. 2000..These results provide evidence that CHI patients access semantic memory automatically at a normal rate. However, when the task is more demanding in terms of processing requests, then CHI patients' performance becomes defective...
Grammatical class effects in brain-damaged patients: functional locus of noun and verb deficitMaria Caterina Silveri
Institute of Neurology, Neuropsychology Service, Catholic University, Rome, Italy
Brain Lang 85:49-66. 2003..The results are discussed within the current models on semantic memory and lexical access...
Category cued recall following controlled encoding as a neuropsychological tool in the diagnosis of Alzheimer's disease: a review of the evidenceGiovanni Augusto Carlesimo
Department of Neuroscience, Tor Vergata University, Rome, Italy
Neuropsychol Rev 21:54-65. 2011....
Neuropsychological predictors of rapidly progressing patients with Alzheimer's diseaseMassimo Musicco
Fondazione Santa Lucia IRCCS, Rome, Italy
Dement Geriatr Cogn Disord 30:219-28. 2010..Different neuropsychological profiles in AD patients might be indicative of the diffusion of the pathological process and might be associated with differences in rates of disease progression...
Category-specific impairment in patients with Alzheimer's disease as a function of disease severity: a cross-sectional investigationGian Daniele Zannino
IRCCS S Lucia, V Ardeatina, 306, 00179, Rome, Italy
Neuropsychologia 40:2268-79. 2002..We did not find any relation between direction of category specificity and severity of the disease or between category specificity and loss of knowledge about perceptual or functional attributes...
The role of semantic distance in category-specific impairments for living things: evidence from a case of semantic dementiaGian Daniele Zannino
Laboratorio di Neurologia, Clinica e Comportamentale, IRCCS S Lucia, Via Ardeatina 306, 00179 Rome, Italy
Neuropsychologia 44:1017-28. 2006..Finally, at variance with the Sensory Functional Theory, although LI quoted sensory features less accurately than nonsensory ones, this did not give rise to a disproportionate loss of semantic features in the living domain...
Manipulating color and other visual information influences picture naming at different levels of processing: evidence from Alzheimer subjects and normal controlsGian Daniele Zannino
I R C C S S Lucia, Roma, Italy
Neuropsychologia 48:2571-8. 2010..Our results suggest that color acts on naming by assisting semantic processing of the stimuli to be recognized; by contrast, photographic detail seems to benefit visual processing by increasing IA...
Category-specific naming deficit in Alzheimer's disease: the effect of a display by domain interactionGian Daniele Zannino
I R C C S S Lucia, Roma, Italy
Neuropsychologia 45:1832-9. 2007..We conclude that our findings lead support to the latter approach...
(Category-specific) semantic deficit in Alzheimer's patients: the role of semantic distanceGian Daniele Zannino
I R C C S Santa Lucia, Laboratorio di Neurologia Clinica e Comportamentale, Via Ardeatina 306, 00179 Rome, Italy
Neuropsychologia 44:52-61. 2006....
The closing-in phenomenon in the drawing performance of Alzheimer's disease patients: a compensation accountLaura Serra
Neuroimaging Laboratory, Foundation IRCCS Santa Lucia, Rome, Italy
Cortex 46:1031-6. 2010..In the present study we examined the hypothesis that in patients with Alzheimer's disease (AD) the phenomenon may be related to particularly severe visuo-spatial dysfunction...
Cognition and behaviour are independent and heterogeneous dimensions in Alzheimer's diseaseGianfranco Spalletta
Department of Neuroscience, University of Tor Vergata, Rome, Italy
J Neurol 251:688-95. 2004..In conclusion, many cognitive and behavioural syndromes exist in patients with AD. However, the results of this study suggest that cognition and behaviour are independent dimensions...
Predictors of progression of cognitive decline in Alzheimer's disease: the role of vascular and sociodemographic factorsMassimo Musicco
Institute of Biomedical Technologies National Research Council, Via F lli Cervi 93, 20099 Segrate, Milan, Italy
J Neurol 256:1288-95. 2009..Our findings suggest a slower disease progression in Alzheimer's patients with diabetes. If confirmed, this result will contribute new insights into Alzheimer's disease pathogenesis and lead to relevant suggestions for disease treatment...
Visual and semantic processing of living things and artifacts: an FMRI studyGian Daniele Zannino
I R C C S S Lucia, 00179 Rome, Italy
J Cogn Neurosci 22:554-70. 2010..Finally, we attempt to reconcile contrasting data in the neuropsychological and functional imaging literature on semantic substrate and category specificity...
Relationship between cognitive impairment and behavioural disturbances in Alzheimer's disease patientsLaura Serra
Neuroimaging Laboratory, Fondazione IRCCS Santa Lucia, Rome, Italy
Behav Neurol 23:123-30. 2010..The aims of the present study were to investigate the relationship between severity and rate of decline of the cognitive and behavioural impairment in patient with AD...
Are the behavioral symptoms of Alzheimer's disease directly associated with neurodegeneration?Laura Serra
Neuroimaging Laboratory, Santa Lucia Foundation, IRCCS, Rome, Italy
J Alzheimers Dis 21:627-39. 2010..Interesting associations were found in regions traditionally implicated by AD neuropathology. This suggests that BPSD are likely to represent clinical features of AD and should be regarded for their diagnostic and prognostic value...
Grey and white matter changes at different stages of Alzheimer's diseaseLaura Serra
Neuroimaging Laboratory, Santa Lucia Foundation, IRCCS, Rome, Italy
J Alzheimers Dis 19:147-59. 2010....
Increased caspase activation in peripheral blood mononuclear cells of patients with Alzheimer's diseaseSantina Tacconi
Department of Experimental Medicine and Biochemical Sciences, University Hospital of Tor Vergata, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
Exp Neurol 190:254-62. 2004....
