Teresa Coccini

Summary

Affiliation: Fondazione Salvatore Maugeri
Country: Italy

Publications

  1. ncbi request reprint Pulmonary toxicity of instilled cadmium-doped silica nanoparticles during acute and subacute stages in rats
    Teresa Coccini
    Salvatore Maugeri Foundation IRCCS, Toxicology Division, University of Pavia, Pavia, Italy
    Histol Histopathol 28:195-209. 2013
  2. doi request reprint Long-lasting oxidative pulmonary insult in rat after intratracheal instillation of silica nanoparticles doped with cadmium
    Teresa Coccini
    Salvatore Maugeri Foundation IRCCS Institute of Pavia, and University of Pavia, Toxicology Division and European Centre for Nanomedicine, Pavia, Italy
    Toxicology 302:203-11. 2012
  3. ncbi request reprint Novel tools for blood inflammatory markers detection in monitoring air pollution-induced cardio-respiratory symptoms
    Teresa Coccini
    Laboratory of Toxicology and European Centre for Nanomedicine, IRCCS Maugeri Foundation Medical Institute and University of Pavia, Pavia, Italy
    G Ital Med Lav Ergon 34:175-86. 2012
  4. ncbi request reprint Comparative HPLC and ELISA studies for CDT isoform characterization in subjects with alcohol related problems. Prospective application in workplace risk-prevention policy
    T Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    G Ital Med Lav Ergon 30:119-27. 2008
  5. doi request reprint Effects of water-soluble functionalized multi-walled carbon nanotubes examined by different cytotoxicity methods in human astrocyte D384 and lung A549 cells
    T Coccini
    Salvatore Maugeri Foundation IRCCS, Research Center for Occupational and Environmental Toxicology, Toxicology Division, Pavia, Italy
    Toxicology 269:41-53. 2010
  6. doi request reprint Reduced platelet monoamine oxidase type B activity and lymphocyte muscarinic receptor binding in unmedicated children with attention deficit hyperactivity disorder
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Biomarkers 14:513-22. 2009
  7. doi request reprint No changes in lymphocyte muscarinic receptors and platelet monoamine oxidase-B examined as surrogate central nervous system biomarkers in a Faroese children cohort prenatally exposed to methylmercury and polychlorinated biphenyls
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Biomarkers 14:67-76. 2009
  8. doi request reprint Developmental exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) affects cerebral dopamine D1-like and D2-like receptors of weanling and pubertal rats
    Teresa Coccini
    Toxicology Division, Research Center for Occupational and Environmental Toxicology, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, via Maugeri, 10, 27100 Pavia, Italy
    Arch Toxicol 85:1281-94. 2011
  9. ncbi request reprint Assessing health effects of environmental contaminants by molecular markers. Studies on methylmercury and polychlorinated biphenyls as examples of translational research in environmental toxicology
    T Coccini
    Salvatore Maugeri Foundation IRCCS, Toxicology Division, Pavia, Italy
    G Ital Med Lav Ergon 32:5-12. 2010
  10. ncbi request reprint Perinatal co-exposure to methylmercury and PCB153 or PCB126 in rats alters the cerebral cholinergic muscarinic receptors at weaning and puberty
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Toxicology 238:34-48. 2007

Detail Information

Publications24

  1. ncbi request reprint Pulmonary toxicity of instilled cadmium-doped silica nanoparticles during acute and subacute stages in rats
    Teresa Coccini
    Salvatore Maugeri Foundation IRCCS, Toxicology Division, University of Pavia, Pavia, Italy
    Histol Histopathol 28:195-209. 2013
    ..The present findings suggest that Cd/SiNPs produce significantly greater pulmonary alterations than either SiNPs or CdCl₂ under the present experimental conditions...
  2. doi request reprint Long-lasting oxidative pulmonary insult in rat after intratracheal instillation of silica nanoparticles doped with cadmium
    Teresa Coccini
    Salvatore Maugeri Foundation IRCCS Institute of Pavia, and University of Pavia, Toxicology Division and European Centre for Nanomedicine, Pavia, Italy
    Toxicology 302:203-11. 2012
    ..SiNPs did not influence any of the evaluated endpoints. The results indicate the capacity of engineered SiNPs-Cd to cause long-lasting oxidative tissue injury following pulmonary exposure in rat...
  3. ncbi request reprint Novel tools for blood inflammatory markers detection in monitoring air pollution-induced cardio-respiratory symptoms
    Teresa Coccini
    Laboratory of Toxicology and European Centre for Nanomedicine, IRCCS Maugeri Foundation Medical Institute and University of Pavia, Pavia, Italy
    G Ital Med Lav Ergon 34:175-86. 2012
    ....
  4. ncbi request reprint Comparative HPLC and ELISA studies for CDT isoform characterization in subjects with alcohol related problems. Prospective application in workplace risk-prevention policy
    T Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    G Ital Med Lav Ergon 30:119-27. 2008
    ..This approach can be applied for alcohol abuse in workplace surveillance...
  5. doi request reprint Effects of water-soluble functionalized multi-walled carbon nanotubes examined by different cytotoxicity methods in human astrocyte D384 and lung A549 cells
    T Coccini
    Salvatore Maugeri Foundation IRCCS, Research Center for Occupational and Environmental Toxicology, Toxicology Division, Pavia, Italy
    Toxicology 269:41-53. 2010
    ..This study indicates that properties obtained by chemical functionalization, such as water solubility, high dispersibility and low agglomeration tendency are relevant factors in modulating cytotoxicity of CNTs...
  6. doi request reprint Reduced platelet monoamine oxidase type B activity and lymphocyte muscarinic receptor binding in unmedicated children with attention deficit hyperactivity disorder
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Biomarkers 14:513-22. 2009
    ....
  7. doi request reprint No changes in lymphocyte muscarinic receptors and platelet monoamine oxidase-B examined as surrogate central nervous system biomarkers in a Faroese children cohort prenatally exposed to methylmercury and polychlorinated biphenyls
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Biomarkers 14:67-76. 2009
    ....
  8. doi request reprint Developmental exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) affects cerebral dopamine D1-like and D2-like receptors of weanling and pubertal rats
    Teresa Coccini
    Toxicology Division, Research Center for Occupational and Environmental Toxicology, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, via Maugeri, 10, 27100 Pavia, Italy
    Arch Toxicol 85:1281-94. 2011
    ..Perinatal exposure to MeHg and/or PCB153 affects D1- and D2-Rs in a gender-, time-, and brain area-dependent manner. Combined treatment does not exacerbate the neurochemical effects of the individual compounds...
  9. ncbi request reprint Assessing health effects of environmental contaminants by molecular markers. Studies on methylmercury and polychlorinated biphenyls as examples of translational research in environmental toxicology
    T Coccini
    Salvatore Maugeri Foundation IRCCS, Toxicology Division, Pavia, Italy
    G Ital Med Lav Ergon 32:5-12. 2010
    ..Studies on pathways and metabolic networks involved in developmental toxicity may contribute to elucidate the mode of action of environmental pollutant mixtures and also considerably impact on the risk assessment process...
  10. ncbi request reprint Perinatal co-exposure to methylmercury and PCB153 or PCB126 in rats alters the cerebral cholinergic muscarinic receptors at weaning and puberty
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Toxicology 238:34-48. 2007
    ..These data support the ability of MeHg and PCBs to induce delayed neurotoxicity after developmental exposure...
  11. doi request reprint Neurodevelopmental toxicity of methylmercury: Laboratory animal data and their contribution to human risk assessment
    Anna F Castoldi
    Toxicology Division, University of Pavia, Via Palestro 26, 27100 Pavia, Italy
    Regul Toxicol Pharmacol 51:215-29. 2008
    ..The ultimate goal is to discuss the relevance of laboratory animal results, as a complementary tool to human data, with regard to the human risk assessment process...
  12. ncbi request reprint Methylmercury interaction with lymphocyte cholinergic muscarinic receptors in developing rats
    Teresa Coccini
    Toxicology Division, Salvatore Maugeri Foundation IRCCS, Institute of Pavia, via Maugeri, 10, 27100 Pavia, Italy
    Environ Res 103:229-37. 2007
    ..The similarity of MeHg IC50 binding data between human and rat in peripheral tissues suggests the possible application of such biomarker to humans exposed to environmental chemicals...
  13. doi request reprint Human developmental neurotoxicity of methylmercury: impact of variables and risk modifiers
    Anna F Castoldi
    Toxicology Division, University of Pavia, Via Palestro 26, 27100 Pavia, Italy
    Regul Toxicol Pharmacol 51:201-14. 2008
    ..These factors, together with the notion that some symptoms may ensue or exacerbate with aging, contribute to the difficulties in the definition of safe levels for developmental exposure...
  14. ncbi request reprint Effects of developmental co-exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) on cholinergic muscarinic receptors in rat brain
    Teresa Coccini
    Toxicology Division, Institute of Pavia, IRCCS Salvatore Maugeri Foundation, Pavia, Italy
    Neurotoxicology 27:468-77. 2006
    ..MR changes were detected in both immature and adult animals and the interaction of MeHg and PCB153 at the level of these receptors occurred in a non-additive manner...
  15. ncbi request reprint Brain monoaminergic neurotransmission parameters in weanling rats after perinatal exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153)
    Anna F Castoldi
    IRCCS Maugeri Foundation, Toxicology Division, Research Centre, Via Palestro 26, 27100 Pavia, Italy
    Brain Res 1112:91-8. 2006
    ..The combined treatment with MeHg and PCB153 does not exacerbate the neurochemical effects of the individual compounds...
  16. doi request reprint Cerebellum cholinergic muscarinic receptor (subtype-2 and -3) and cytoarchitecture after developmental exposure to methylmercury: an immunohistochemical study in rat
    Elisa Roda
    University of Pavia, Department of Internal Medicine and Therapeutics, Toxicology Division, Pavia, Italy
    J Chem Neuroanat 35:285-94. 2008
    ..g. reactive gliosis, (iii) a selective vulnerability of granule cells and Purkinje neurons to MeHg, with the latter that remain unharmed...
  17. ncbi request reprint Lymphocyte cytochrome c oxidase, cyclic GMP and cholinergic muscarinic receptors as peripheral indicators of carbon monoxide neurotoxicity after acute and repeated exposure in the rat
    Anna F Castoldi
    Toxicology Division, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, Via Ferrata 8, 27100 Pavia, Italy
    Life Sci 78:1915-24. 2006
    ..Journal of Neurochemistry 89, 1,157-1,165], and supports the use of this peripheral endpoint as a biomarker of CO central effects...
  18. ncbi request reprint Platelet monoamine oxidase B activity as a state marker for alcoholism: trend over time during withdrawal and influence of smoking and gender
    Teresa Coccini
    Toxicology Division, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, Italy
    Alcohol Alcohol 37:566-72. 2002
    ....
  19. ncbi request reprint Neurotoxic and molecular effects of methylmercury in humans
    Anna F Castoldi
    Toxicology Division, Salvatore Maugeri Foundation IRCCS, Institute of Pavia, Pavia, Italy
    Rev Environ Health 18:19-31. 2003
    ....
  20. doi request reprint Apoptosis induction and histological changes in rat kidney following Cd-doped silica nanoparticle exposure: evidence of persisting effects
    Teresa Coccini
    Laboratory of Clinical Toxicology, Salvatore Maugeri Foundation IRCCS, University of Pavia, Pavia, Italy and
    Toxicol Mech Methods 23:566-75. 2013
    ..These findings substantiate the notion that multiple assays and an integrated testing strategy should be recommended to characterize toxicological responses to nanoparticles in mammalian systems...
  21. ncbi request reprint Prolonged ethanol ingestion enhances benzene myelotoxicity and lowers urinary concentrations of benzene metabolite levels in CD-1 male mice
    Giorgio Marrubini
    Research Centre, Toxicology Division, Department of Internal Medicine, University of Pavia, Pavia, Italy
    Toxicol Sci 75:16-24. 2003
    ....
  22. doi request reprint Assessment of Cellular Responses after Short- and Long-Term Exposure to Silver Nanoparticles in Human Neuroblastoma (SH-SY5Y) and Astrocytoma (D384) Cells
    Teresa Coccini
    Laboratory of Clinical Toxicology, IRCCS Salvatore Maugeri Foundation, Scientific Institute of Pavia Medical Centre, Via Maugeri 10, 27100 Pavia, Italy Toxicology Division, Department of Environmental Health, IRCCS Salvatore Maugeri Foundation, Scientific Institute of Pavia Medical Centre, Via Maugeri 10, 27100 Pavia, Italy
    ScientificWorldJournal 2014:259765. 2014
    ..In summary, AgNP-induced cytotoxic effects after short-term and prolonged exposure (even at low doses) were evidenced regardless of cell model types. ..
  23. pmc Safety evaluation of engineered nanomaterials for health risk assessment: an experimental tiered testing approach using pristine and functionalized carbon nanotubes
    Teresa Coccini
    Laboratory of Clinical Toxicology, IRCCS Maugeri Foundation, Medical Institute of Pavia, and University of Pavia, via Maugeri, 1027100 Pavia, Italy
    ISRN Toxicol 2013:825427. 2013
    ..This multitiered approach contributed to clarifying the CNT toxicity mechanisms improving the overall understanding of the possible adverse outcomes resulting from CNT exposure...
  24. ncbi request reprint Diagnostic accuracy of urinary amanitin in suspected mushroom poisoning: a pilot study
    Raffaella Butera
    Pavia Poison Center and Toxicology Laboratory, IRCCS Maugeri Foundation and University of Pavia, Pavia, Italy
    J Toxicol Clin Toxicol 42:901-12. 2004
    ..Therefore, this poisoning should be ruled out in all patients presenting gastrointestinal symptoms after wild mushroom ingestion...