Antonio Ciaramella

Summary

Affiliation: Fondazione Santa Lucia
Country: Italy

Publications

  1. ncbi request reprint Amyloid beta peptide promotes differentiation of pro-inflammatory human myeloid dendritic cells
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy
    Neurobiol Aging 30:210-21. 2009
  2. doi request reprint Myeloid dendritic cells are decreased in peripheral blood of Alzheimer's disease patients in association with disease progression and severity of depressive symptoms
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Experimental Neuro psychobiology Lab, Via Ardeatina 306, 00179, Rome, Italy
    J Neuroinflammation 13:18. 2016
  3. doi request reprint The stimulation of dendritic cells by amyloid beta 1-42 reduces BDNF production in Alzheimer's disease patients
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy
    Brain Behav Immun 32:29-32. 2013
  4. doi request reprint Effect of age on surface molecules and cytokine expression in human dendritic cells
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy
    Cell Immunol 269:82-9. 2011
  5. doi request reprint Increased pro-inflammatory response by dendritic cells from patients with Alzheimer's disease
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy
    J Alzheimers Dis 19:559-72. 2010
  6. ncbi request reprint Interleukin-18 produced by peripheral blood cells is increased in Alzheimer's disease and correlates with cognitive impairment
    Paola Bossù
    IRCCS Santa Lucia Foundation, Department of Clinical and Behavioural Neurology, Via Ardeatina 306, 00179 Rome, Italy
    Brain Behav Immun 22:487-92. 2008
  7. ncbi request reprint Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) patients are characterized by increased BDNF serum levels
    Francesco Angelucci
    Department of Clinical and Behavioural Neurology, 00179, Rome, Italy
    Curr Alzheimer Res 7:15-20. 2010
  8. pmc Blood dendritic cell frequency declines in idiopathic Parkinson's disease and is associated with motor symptom severity
    Antonio Ciaramella
    Clinical and Behavioral Neurology, IRCCS Fondazione Santa Lucia, Rome, Italy
    PLoS ONE 8:e65352. 2013
  9. pmc Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia
    Ilaria Palladino
    Clinical and Behavioral Neurology, IRCCS Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy
    J Neuroinflammation 9:206. 2012
  10. doi request reprint Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and Alzheimer's disease
    Francesca Salani
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, I 00179 Rome, Italy
    Cytokine 61:360-3. 2013

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Amyloid beta peptide promotes differentiation of pro-inflammatory human myeloid dendritic cells
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy
    Neurobiol Aging 30:210-21. 2009
    ..These results demonstrate that A beta 42 can modulate the immune system by inducing pro-inflammatory DC differentiation, thus gaining new insights into AD pathogenesis and immune-based therapeutic intervention...
  2. doi request reprint Myeloid dendritic cells are decreased in peripheral blood of Alzheimer's disease patients in association with disease progression and severity of depressive symptoms
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Experimental Neuro psychobiology Lab, Via Ardeatina 306, 00179, Rome, Italy
    J Neuroinflammation 13:18. 2016
    ....
  3. doi request reprint The stimulation of dendritic cells by amyloid beta 1-42 reduces BDNF production in Alzheimer's disease patients
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy
    Brain Behav Immun 32:29-32. 2013
    ..Thus, possibly due to their Aβ-induced reduction of neurotrophic support to neurons, DCs from AD patients might contribute to brain damage by playing a part in Aβ-dependent neuronal toxicity...
  4. doi request reprint Effect of age on surface molecules and cytokine expression in human dendritic cells
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy
    Cell Immunol 269:82-9. 2011
    ..Altogether, the present results point to additional molecules whose role might be relevant in immunosenescence of human DCs, confirming that these cells undergo functional changes during aging...
  5. doi request reprint Increased pro-inflammatory response by dendritic cells from patients with Alzheimer's disease
    Antonio Ciaramella
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy
    J Alzheimers Dis 19:559-72. 2010
    ....
  6. ncbi request reprint Interleukin-18 produced by peripheral blood cells is increased in Alzheimer's disease and correlates with cognitive impairment
    Paola Bossù
    IRCCS Santa Lucia Foundation, Department of Clinical and Behavioural Neurology, Via Ardeatina 306, 00179 Rome, Italy
    Brain Behav Immun 22:487-92. 2008
    ....
  7. ncbi request reprint Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) patients are characterized by increased BDNF serum levels
    Francesco Angelucci
    Department of Clinical and Behavioural Neurology, 00179, Rome, Italy
    Curr Alzheimer Res 7:15-20. 2010
    ..Other studies are necessary to establish a direct link between BDNF peripheral levels and AD longitudinal course, as well as the role of other factors, such as blood cell activation, in determining these events...
  8. pmc Blood dendritic cell frequency declines in idiopathic Parkinson's disease and is associated with motor symptom severity
    Antonio Ciaramella
    Clinical and Behavioral Neurology, IRCCS Fondazione Santa Lucia, Rome, Italy
    PLoS ONE 8:e65352. 2013
    ....
  9. pmc Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia
    Ilaria Palladino
    Clinical and Behavioral Neurology, IRCCS Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, Italy
    J Neuroinflammation 9:206. 2012
    ....
  10. doi request reprint Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and Alzheimer's disease
    Francesca Salani
    Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, I 00179 Rome, Italy
    Cytokine 61:360-3. 2013
    ....
  11. pmc Different transcriptional profiles of human monocyte-derived dendritic cells infected with distinct strains of Mycobacterium tuberculosis and Mycobacterium bovis bacillus Calmette-Guérin
    Nunzia Sanarico
    Institute of Cell Biology and Neurobiology, National Research Council, Rome, Italy
    Clin Dev Immunol 2011:741051. 2011
    ..Our results suggest that DCs display the ability to elicit a tailored strain-specific immune response...
  12. ncbi request reprint Dendritic cells derived from BCG-infected precursors induce Th2-like immune response
    Angelo Martino
    National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy
    J Leukoc Biol 76:827-34. 2004
    ..The induction of IL-4 production by DCs generated by BCG-infected monocytes could explain the failure of the BCG vaccine to prevent pulmonary tuberculosis...
  13. pmc Interleukin 18 gene polymorphisms predict risk and outcome of Alzheimer's disease
    Paola Bossù
    IRCCS Santa Lucia Foundation, Rome, Italy
    J Neurol Neurosurg Psychiatry 78:807-11. 2007
    ..The aim of this study was to investigate the impact of two polymorphisms of the human IL-18 gene promoter at positions -607 (C/A) and -137 (G/C) on both susceptibility to and progression of AD...
  14. doi request reprint Increased levels of serum IL-18 are associated with the long-term outcome of severe traumatic brain injury
    Antonio Ciaramella
    Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome, Italy
    Neuroimmunomodulation 21:8-12. 2014
    ..Here we aimed to evaluate the impact of interleukin (IL)-18, a proinflammatory cytokine elevated in post-acute head injury and associated with neurodegeneration, on the long-term outcome of patients with chronic TBI...
  15. pmc IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease
    Paola Bossù
    Laboratory of Clinical and Behavioral Neurology, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Santa Lucia, 00179 Rome, Italy
    Proc Natl Acad Sci U S A 100:14181-6. 2003
    ..These studies support the concept that IL-18 plays a major role in the pathogenesis of the autoimmune syndrome of lpr mice and that a reduction in IL-18 activity could be a therapeutic strategy in autoimmune diseases...