Anna F Castoldi

Summary

Affiliation: Fondazione Salvatore Maugeri
Country: Italy

Publications

  1. doi Neurodevelopmental toxicity of methylmercury: Laboratory animal data and their contribution to human risk assessment
    Anna F Castoldi
    Toxicology Division, University of Pavia, Via Palestro 26, 27100 Pavia, Italy
    Regul Toxicol Pharmacol 51:215-29. 2008
  2. doi Human developmental neurotoxicity of methylmercury: impact of variables and risk modifiers
    Anna F Castoldi
    Toxicology Division, University of Pavia, Via Palestro 26, 27100 Pavia, Italy
    Regul Toxicol Pharmacol 51:201-14. 2008
  3. doi Developmental exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) affects cerebral dopamine D1-like and D2-like receptors of weanling and pubertal rats
    Teresa Coccini
    Toxicology Division, Research Center for Occupational and Environmental Toxicology, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, via Maugeri, 10, 27100 Pavia, Italy
    Arch Toxicol 85:1281-94. 2011
  4. ncbi Perinatal co-exposure to methylmercury and PCB153 or PCB126 in rats alters the cerebral cholinergic muscarinic receptors at weaning and puberty
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Toxicology 238:34-48. 2007
  5. ncbi Methylmercury interaction with lymphocyte cholinergic muscarinic receptors in developing rats
    Teresa Coccini
    Toxicology Division, Salvatore Maugeri Foundation IRCCS, Institute of Pavia, via Maugeri, 10, 27100 Pavia, Italy
    Environ Res 103:229-37. 2007
  6. ncbi Brain monoaminergic neurotransmission parameters in weanling rats after perinatal exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153)
    Anna F Castoldi
    IRCCS Maugeri Foundation, Toxicology Division, Research Centre, Via Palestro 26, 27100 Pavia, Italy
    Brain Res 1112:91-8. 2006
  7. ncbi Effects of developmental co-exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) on cholinergic muscarinic receptors in rat brain
    Teresa Coccini
    Toxicology Division, Institute of Pavia, IRCCS Salvatore Maugeri Foundation, Pavia, Italy
    Neurotoxicology 27:468-77. 2006
  8. ncbi Neurotoxic and molecular effects of methylmercury in humans
    Anna F Castoldi
    Toxicology Division, Salvatore Maugeri Foundation IRCCS, Institute of Pavia, Pavia, Italy
    Rev Environ Health 18:19-31. 2003
  9. ncbi Lymphocyte cytochrome c oxidase, cyclic GMP and cholinergic muscarinic receptors as peripheral indicators of carbon monoxide neurotoxicity after acute and repeated exposure in the rat
    Anna F Castoldi
    Toxicology Division, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, Via Ferrata 8, 27100 Pavia, Italy
    Life Sci 78:1915-24. 2006
  10. ncbi Prolonged ethanol ingestion enhances benzene myelotoxicity and lowers urinary concentrations of benzene metabolite levels in CD-1 male mice
    Giorgio Marrubini
    Research Centre, Toxicology Division, Department of Internal Medicine, University of Pavia, Pavia, Italy
    Toxicol Sci 75:16-24. 2003

Detail Information

Publications13

  1. doi Neurodevelopmental toxicity of methylmercury: Laboratory animal data and their contribution to human risk assessment
    Anna F Castoldi
    Toxicology Division, University of Pavia, Via Palestro 26, 27100 Pavia, Italy
    Regul Toxicol Pharmacol 51:215-29. 2008
    ..The ultimate goal is to discuss the relevance of laboratory animal results, as a complementary tool to human data, with regard to the human risk assessment process...
  2. doi Human developmental neurotoxicity of methylmercury: impact of variables and risk modifiers
    Anna F Castoldi
    Toxicology Division, University of Pavia, Via Palestro 26, 27100 Pavia, Italy
    Regul Toxicol Pharmacol 51:201-14. 2008
    ..These factors, together with the notion that some symptoms may ensue or exacerbate with aging, contribute to the difficulties in the definition of safe levels for developmental exposure...
  3. doi Developmental exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) affects cerebral dopamine D1-like and D2-like receptors of weanling and pubertal rats
    Teresa Coccini
    Toxicology Division, Research Center for Occupational and Environmental Toxicology, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, via Maugeri, 10, 27100 Pavia, Italy
    Arch Toxicol 85:1281-94. 2011
    ..Perinatal exposure to MeHg and/or PCB153 affects D1- and D2-Rs in a gender-, time-, and brain area-dependent manner. Combined treatment does not exacerbate the neurochemical effects of the individual compounds...
  4. ncbi Perinatal co-exposure to methylmercury and PCB153 or PCB126 in rats alters the cerebral cholinergic muscarinic receptors at weaning and puberty
    Teresa Coccini
    IRCCS Salvatore Maugeri Foundation, Toxicology Division, Institute of Pavia, Italy
    Toxicology 238:34-48. 2007
    ..These data support the ability of MeHg and PCBs to induce delayed neurotoxicity after developmental exposure...
  5. ncbi Methylmercury interaction with lymphocyte cholinergic muscarinic receptors in developing rats
    Teresa Coccini
    Toxicology Division, Salvatore Maugeri Foundation IRCCS, Institute of Pavia, via Maugeri, 10, 27100 Pavia, Italy
    Environ Res 103:229-37. 2007
    ..The similarity of MeHg IC50 binding data between human and rat in peripheral tissues suggests the possible application of such biomarker to humans exposed to environmental chemicals...
  6. ncbi Brain monoaminergic neurotransmission parameters in weanling rats after perinatal exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153)
    Anna F Castoldi
    IRCCS Maugeri Foundation, Toxicology Division, Research Centre, Via Palestro 26, 27100 Pavia, Italy
    Brain Res 1112:91-8. 2006
    ..The combined treatment with MeHg and PCB153 does not exacerbate the neurochemical effects of the individual compounds...
  7. ncbi Effects of developmental co-exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) on cholinergic muscarinic receptors in rat brain
    Teresa Coccini
    Toxicology Division, Institute of Pavia, IRCCS Salvatore Maugeri Foundation, Pavia, Italy
    Neurotoxicology 27:468-77. 2006
    ..MR changes were detected in both immature and adult animals and the interaction of MeHg and PCB153 at the level of these receptors occurred in a non-additive manner...
  8. ncbi Neurotoxic and molecular effects of methylmercury in humans
    Anna F Castoldi
    Toxicology Division, Salvatore Maugeri Foundation IRCCS, Institute of Pavia, Pavia, Italy
    Rev Environ Health 18:19-31. 2003
    ....
  9. ncbi Lymphocyte cytochrome c oxidase, cyclic GMP and cholinergic muscarinic receptors as peripheral indicators of carbon monoxide neurotoxicity after acute and repeated exposure in the rat
    Anna F Castoldi
    Toxicology Division, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, Via Ferrata 8, 27100 Pavia, Italy
    Life Sci 78:1915-24. 2006
    ..Journal of Neurochemistry 89, 1,157-1,165], and supports the use of this peripheral endpoint as a biomarker of CO central effects...
  10. ncbi Prolonged ethanol ingestion enhances benzene myelotoxicity and lowers urinary concentrations of benzene metabolite levels in CD-1 male mice
    Giorgio Marrubini
    Research Centre, Toxicology Division, Department of Internal Medicine, University of Pavia, Pavia, Italy
    Toxicol Sci 75:16-24. 2003
    ....
  11. ncbi Platelet monoamine oxidase B activity as a state marker for alcoholism: trend over time during withdrawal and influence of smoking and gender
    Teresa Coccini
    Toxicology Division, IRCCS Salvatore Maugeri Foundation, Institute of Pavia, Italy
    Alcohol Alcohol 37:566-72. 2002
    ....
  12. ncbi Neurobehavioural and molecular changes induced by methylmercury exposure during development
    Carolina Johansson
    Division of Toxicology and Neurotoxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Neurotox Res 11:241-60. 2007
    ..This review summarises what is currently known about the neurodevelopmental effects of MeHg and consider the strength of different experimental approaches to study the effects of environmentally relevant exposure in vivo and in vitro...
  13. ncbi In vivo exposure to carbon monoxide causes delayed impairment of activation of soluble guanylate cyclase by nitric oxide in rat brain cortex and cerebellum
    Mariluz Hernandez-Viadel
    Laboratory of Neurobiology, Fundacion Valenciana de Investigaciones Biomedicas, Amadeo de Saboya 4, 46010 Valencia, Spain
    J Neurochem 89:1157-65. 2004
    ..This delayed impaired modulation of soluble guanylate cyclase by nitric oxide may contribute to delayed memory loss and cognitive impairment in humans exposed to carbon monoxide...