Daniele Focosi

Summary

Country: Italy

Publications

  1. doi request reprint Lithium and hematology: established and proposed uses
    Daniele Focosi
    Azienda Ospedaliera Santa Chiara, University of Pisa, Via Roma 56, 56100 Pisa, Italy
    J Leukoc Biol 85:20-8. 2009
  2. doi request reprint Immunosuppressive monoclonal antibodies: current and next generation
    D Focosi
    U O Immuoematologia SSN, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
    Clin Microbiol Infect 17:1759-68. 2011
  3. doi request reprint Progressive multifocal leukoencephalopathy: what's new?
    Daniele Focosi
    Department of Oncology, Transplants and Advances in Medicine, Division of Hematology, University of Pisa, Pisa, Italy
    Neuroscientist 16:308-23. 2010
  4. doi request reprint Cancer transmissibility across HLA barriers between immunocompetent individuals: rare but not impossible
    Daniele Focosi
    Laboratory of Immunogenetics, Division of Immunohematology, Azienda Ospedaliera Universitaria Pisana, Italy
    Hum Immunol 72:1-4. 2011
  5. doi request reprint CD57+ T lymphocytes and functional immune deficiency
    Daniele Focosi
    Division of Hematology, Azienda Ospedaliera Santa Chiara, University of Pisa, Via Roma, Pisa, Italy
    J Leukoc Biol 87:107-16. 2010
  6. doi request reprint Hypercytokinemia-induced metabolic encephalopathy in a multiple myeloma patient on hemodialysis undergoing autologous stem cell transplantation: clinical response after plasma exchange
    Daniele Focosi
    Division of Hematology, Department of Oncology, Transplants and Advances in Medicine, University of Pisa, Italy
    Transpl Immunol 21:240-3. 2009
  7. doi request reprint Fatal ongoing human cytomegalovirus reactivation during high-dose melphalan and autologous stem cell transplantation
    Daniele Focosi
    Division of Hematology, Department of Oncology, Transplants and Advances in Medicine, University of Pisa, Pisa, Italy
    J Med Virol 81:857-60. 2009
  8. doi request reprint Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractory to intravenous and intravesical cidofovir: case report and review of literature
    Daniele Focosi
    Division of Hematology, Department of Oncology, Transplantations and New Technologies in Medicine, University of Pisa, Italy
    Leuk Res 33:556-60. 2009
  9. doi request reprint The role of anti-HLA antibodies in hematopoietic stem cell transplantation
    Daniele Focosi
    Division of Immunohematology, Azienda Ospedaliero Univeritaria Pisana, Via Paradisa 2, Pisa, Italy
    Biol Blood Marrow Transplant 17:1585-8. 2011
  10. ncbi request reprint Progressive multifocal leukoencephalopathy: report of three cases in HIV-negative hematological patients and review of literature
    Matteo Pelosini
    Division of Haematology, Department of Oncology, Transplants and Advances in Medicine, University of Pisa, Pisa, Italy
    Ann Hematol 87:405-12. 2008

Collaborators

Detail Information

Publications22

  1. doi request reprint Lithium and hematology: established and proposed uses
    Daniele Focosi
    Azienda Ospedaliera Santa Chiara, University of Pisa, Via Roma 56, 56100 Pisa, Italy
    J Leukoc Biol 85:20-8. 2009
    ..We suggest possible therapeutic uses of lithium in neutropenia. In bone marrow transplantation, preharvest lithium-assisted hematopoietic stem cell mobilization may be useful as well...
  2. doi request reprint Immunosuppressive monoclonal antibodies: current and next generation
    D Focosi
    U O Immuoematologia SSN, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
    Clin Microbiol Infect 17:1759-68. 2011
    ..We review here the current and next generation of mAbs and the risks that infectious disease specialists should be aware of...
  3. doi request reprint Progressive multifocal leukoencephalopathy: what's new?
    Daniele Focosi
    Department of Oncology, Transplants and Advances in Medicine, Division of Hematology, University of Pisa, Pisa, Italy
    Neuroscientist 16:308-23. 2010
    ..In recent years, immunosuppressive therapeutic antibodies have been associated with an increased incidence rate of PML. Here, the authors review findings on the pathogenesis of PML and the encouraging case reports of novel treatments...
  4. doi request reprint Cancer transmissibility across HLA barriers between immunocompetent individuals: rare but not impossible
    Daniele Focosi
    Laboratory of Immunogenetics, Division of Immunohematology, Azienda Ospedaliera Universitaria Pisana, Italy
    Hum Immunol 72:1-4. 2011
    ..We review here evidence from nonhuman models and settings for interhuman transmission...
  5. doi request reprint CD57+ T lymphocytes and functional immune deficiency
    Daniele Focosi
    Division of Hematology, Azienda Ospedaliera Santa Chiara, University of Pisa, Via Roma, Pisa, Italy
    J Leukoc Biol 87:107-16. 2010
    ..We review here the relevant literature and implications in clinical settings...
  6. doi request reprint Hypercytokinemia-induced metabolic encephalopathy in a multiple myeloma patient on hemodialysis undergoing autologous stem cell transplantation: clinical response after plasma exchange
    Daniele Focosi
    Division of Hematology, Department of Oncology, Transplants and Advances in Medicine, University of Pisa, Italy
    Transpl Immunol 21:240-3. 2009
    ..We discuss here the pathogenesis and raise an alert for monitoring cytokine levels in patients with renal failure undergoing high-dose chemotherapy...
  7. doi request reprint Fatal ongoing human cytomegalovirus reactivation during high-dose melphalan and autologous stem cell transplantation
    Daniele Focosi
    Division of Hematology, Department of Oncology, Transplants and Advances in Medicine, University of Pisa, Pisa, Italy
    J Med Virol 81:857-60. 2009
    ..This case report describes a patient who underwent high-dose melphalan and autologous transplantation with unknown active HCMV replication...
  8. doi request reprint Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractory to intravenous and intravesical cidofovir: case report and review of literature
    Daniele Focosi
    Division of Hematology, Department of Oncology, Transplantations and New Technologies in Medicine, University of Pisa, Italy
    Leuk Res 33:556-60. 2009
    ..We review the literature for therapeutic options in hemorrhagic cystitis and try to explain how hyperbaric oxygen stimulates mucosal repair in the urinary bladder...
  9. doi request reprint The role of anti-HLA antibodies in hematopoietic stem cell transplantation
    Daniele Focosi
    Division of Immunohematology, Azienda Ospedaliero Univeritaria Pisana, Via Paradisa 2, Pisa, Italy
    Biol Blood Marrow Transplant 17:1585-8. 2011
    ..We summarize here evidence supporting a role for DSHA in graft failure in animal models of allo-HSCT and in clinical settings whenever no full HLA matching occurs...
  10. ncbi request reprint Progressive multifocal leukoencephalopathy: report of three cases in HIV-negative hematological patients and review of literature
    Matteo Pelosini
    Division of Haematology, Department of Oncology, Transplants and Advances in Medicine, University of Pisa, Pisa, Italy
    Ann Hematol 87:405-12. 2008
    ..All of them received rituximab, which has recently been in the focus of a Food and Drug Administration warning...
  11. pmc Role of hematopoietic cells in the maintenance of chronic human torquetenovirus plasma viremia
    Fabrizio Maggi
    Virology Section and Retrovirus Centre, Department of Experimental Pathology, University of Pisa, Italy, Via San Zeno, 35 37, 56127 Pisa, Italy
    J Virol 84:6891-3. 2010
    ..The findings provide clear quantitative evidence for an extremely important role of hematopoietic cells in the maintenance of TTV viremia...
  12. pmc Human gyrovirus DNA in human blood, Italy
    Fabrizio Maggi
    Pisa University Hospital, Pisa, Italy
    Emerg Infect Dis 18:956-9. 2012
    ..These results show that HGyV can be present in the blood of infected persons. Additional studies are needed to investigate possible clinical implications...
  13. doi request reprint Phenobarbital-associated bone marrow aplasia: a case report and review of the literature
    Daniele Focosi
    Division of Hematology, Azienda Ospedaliera Universitaria Santa Chiara, Pisa, Italy
    Acta Haematol 119:18-21. 2008
    ..We discuss here the potential mechanisms by which phenobarbital and other anti-epileptic drugs can cause aplastic anemia and review the literature for previous case reports and epidemiological studies...
  14. doi request reprint Transplantation of the pancreas
    Ugo Boggi
    Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, Universita di Pisa, Via Paradisa 2, 56124, Pisa, Italy
    Curr Diab Rep 12:568-79. 2012
    ..Refinements in graft preservation, surgical techniques, immunosuppression, and prophylactic treatments are expected to further improve the results of pancreas transplantation...
  15. doi request reprint Torquetenovirus viremia kinetics after autologous stem cell transplantation are predictable and may serve as a surrogate marker of functional immune reconstitution
    Daniele Focosi
    Division of Hematology, Azienda Ospedaliera Universitaria Pisana Santa Chiara, Pisa, Italy
    J Clin Virol 47:189-92. 2010
    ..It is common experience that retreating patients too early after a course of intensive chemotherapy predisposes to opportunistic infections despite apparently normal lymphocyte levels...
  16. doi request reprint Conditioning response to granulocyte colony-stimulating factor via the dipeptidyl peptidase IV-adenosine deaminase complex
    Daniele Focosi
    Division of Hematology, Azienda Ospedaliera Santa Chiara, University of Pisa, Via Roma 56, 56100 Pisa, Italy
    J Leukoc Biol 84:331-7. 2008
    ..CXCL12 inactivation is primarily mediated by dipeptidyl peptidase-IV. We review here the currently available drugs affecting this enzyme that could be used in the clinic to achieve phase-specific help for G-CSF...
  17. doi request reprint Acute myeloid leukaemia after treatment with (90)Y-ibritumomab tiuxetan for follicular lymphoma
    Daniele Focosi
    Division of Hematology, Department of Oncology, Transplantations and New Technologies in Medicine, University of Pisa, Italy
    Hematol Oncol 26:179-81. 2008
    ..We review the literature for the potential causal relationship between RIT and secondary myelodysplastic syndromes/acute myeloid leukaemia...
  18. doi request reprint Association of donor-specific microchimerism with graft dysfunction in kidney transplant patients
    Michele Curcio
    Immunohematology Unit, Cisanello Hospital, Pisa, Italy
    Transpl Immunol 26:151-5. 2012
    ..2 out of 11 DSM positive had lost their transplanted organ. In conclusion, qRT-PCR applied to peripheral blood shows significant association between DSM and allograft dysfunction in kidney transplant patients...
  19. pmc Inclusion of rituximab in treatment protocols for non-Hodgkin's lymphomas and risk for progressive multifocal leukoencephalopathy
    Marco Tuccori
    Department of Experimental Pathology, University of Pisa, Pisa, Italy
    Oncologist 15:1214-9. 2010
    ..2 every 1,000 patient-years; 95% confidence interval, 0.1-4.3). Interpretation. Based on this finding, clinical surveillance of PML-related symptoms is recommended in NHL patients exposed to rituximab...
  20. ncbi request reprint Progressive multifocal leukoencephalopathy in a haploidentical stem cell transplant recipient: a clinical, neuroradiological and virological response after treatment with risperidone
    Daniele Focosi
    Division of Hematology, Azienda Ospedaliera Universitaria Santa Chiara, Via Roma 56, 56100 Pisa, Italy
    Antiviral Res 74:156-8. 2007
    ..Since risperidone is the tightest binding of current drugs to this receptor we think this may have blocked JCV entry in our patient, allowing her immune recovery and viral clearance...
  21. doi request reprint Laparoscopic robot-assisted pancreas transplantation: first world experience
    Ugo Boggi
    Division of General and Transplant Surgery, Pisa University Hospital, Pisa, Italy
    Transplantation 93:201-6. 2012
    ..The da Vinci surgical system, a computer-assisted electromechanical device, provides the unique opportunity to test whether laparoscopy can reduce the morbidity of pancreas transplantation...
  22. ncbi request reprint Acute myeloid leukemia and follicular lymphoma after very low dose radioiodine therapy for thyroid diseases
    Daniele Focosi
    Division of Hematology, Azienda Ospedaliera Universitaria Santa Chiara, Pisa, Italy
    Haematologica 92:e96-7. 2007