F Fiorentino

Summary

Country: Italy

Publications

  1. doi request reprint Polymerase chain reaction-based detection of chromosomal imbalances on embryos: the evolution of preimplantation genetic diagnosis for chromosomal translocations
    Francesco Fiorentino
    Genoma, Molecular Genetics Laboratory, Rome, Italy
    Fertil Steril 94:2001-11, 2011.e1-6. 2010
  2. ncbi request reprint Development and validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of embryos
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy Electronic address
    Fertil Steril 101:1375-82. 2014
  3. pmc Chromosomal microarray analysis as a first-line test in pregnancies with a priori low risk for the detection of submicroscopic chromosomal abnormalities
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy
    Eur J Hum Genet 21:725-30. 2013
  4. doi request reprint Array comparative genomic hybridization: its role in preimplantation genetic diagnosis
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy
    Curr Opin Obstet Gynecol 24:203-9. 2012
  5. doi request reprint Molecular genetic analysis of single cells
    Francesco Fiorentino
    Genoma, Molecular Genetics Laboratory, Rome, Italy
    Semin Reprod Med 30:267-82. 2012
  6. pmc Genome profiling of ovarian adenocarcinomas using pangenomic BACs microarray comparative genomic hybridization
    Donatella Caserta
    Oby Gyn Dept, Saint Andrea Hospital, University of Roma La Sapienza, Rome, Italy
    Mol Cytogenet 1:10. 2008
  7. doi request reprint Introducing array comparative genomic hybridization into routine prenatal diagnosis practice: a prospective study on over 1000 consecutive clinical cases
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, via Po, 102 00198, Rome, Italy
    Prenat Diagn 31:1270-82. 2011
  8. doi request reprint PGD for reciprocal and Robertsonian translocations using array comparative genomic hybridization
    F Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy
    Hum Reprod 26:1925-35. 2011
  9. ncbi request reprint Gene symbol: WAS. Disease: Wiskott-Aldrich syndrome
    F Fiorentino
    Hum Genet 116:539. 2005
  10. ncbi request reprint The minisequencing method: an alternative strategy for preimplantation genetic diagnosis of single gene disorders
    F Fiorentino
    GENOMA Molecular Genetics Laboratory, via Po nr 102, 00198 Rome
    Mol Hum Reprod 9:399-410. 2003

Detail Information

Publications14

  1. doi request reprint Polymerase chain reaction-based detection of chromosomal imbalances on embryos: the evolution of preimplantation genetic diagnosis for chromosomal translocations
    Francesco Fiorentino
    Genoma, Molecular Genetics Laboratory, Rome, Italy
    Fertil Steril 94:2001-11, 2011.e1-6. 2010
    ..To develop and assess a polymerase chain reaction (PCR)-based preimplantation genetic diagnosis (PGD) approach for detection of chromosomal imbalances in embryos...
  2. ncbi request reprint Development and validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of embryos
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy Electronic address
    Fertil Steril 101:1375-82. 2014
    ..To validate a next-generation sequencing (NGS)-based method for 24-chromosome aneuploidy screening and to investigate its applicability to preimplantation genetic screening (PGS)...
  3. pmc Chromosomal microarray analysis as a first-line test in pregnancies with a priori low risk for the detection of submicroscopic chromosomal abnormalities
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy
    Eur J Hum Genet 21:725-30. 2013
    ..Our findings provide substantial evidence for the introduction of CMA as a first-line diagnostic test for all pregnant women undergoing invasive prenatal testing, regardless of risk factors...
  4. doi request reprint Array comparative genomic hybridization: its role in preimplantation genetic diagnosis
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy
    Curr Opin Obstet Gynecol 24:203-9. 2012
    ..The use of preimplantation genetic diagnosis by array comparative genomic hybridization, for comprehensive aneuploidy screening of embryos, to improve IVF outcomes, is reviewed...
  5. doi request reprint Molecular genetic analysis of single cells
    Francesco Fiorentino
    Genoma, Molecular Genetics Laboratory, Rome, Italy
    Semin Reprod Med 30:267-82. 2012
    ..The new PGD techniques will empower patients and clinicians to screen for almost any kind of genetic problem in embryos, with the potential to change completely the manner in which parents approach and manage genetic disease...
  6. pmc Genome profiling of ovarian adenocarcinomas using pangenomic BACs microarray comparative genomic hybridization
    Donatella Caserta
    Oby Gyn Dept, Saint Andrea Hospital, University of Roma La Sapienza, Rome, Italy
    Mol Cytogenet 1:10. 2008
    ....
  7. doi request reprint Introducing array comparative genomic hybridization into routine prenatal diagnosis practice: a prospective study on over 1000 consecutive clinical cases
    Francesco Fiorentino
    GENOMA Molecular Genetics Laboratory, via Po, 102 00198, Rome, Italy
    Prenat Diagn 31:1270-82. 2011
    ....
  8. doi request reprint PGD for reciprocal and Robertsonian translocations using array comparative genomic hybridization
    F Fiorentino
    GENOMA Molecular Genetics Laboratory, Rome, Italy
    Hum Reprod 26:1925-35. 2011
    ..We describe the clinical application of a molecular-based assay, array comparative genomic hybridization (array-CGH), to simultaneously screen for unbalanced translocation derivatives and aneuploidy of all 24 chromosomes...
  9. ncbi request reprint Gene symbol: WAS. Disease: Wiskott-Aldrich syndrome
    F Fiorentino
    Hum Genet 116:539. 2005
  10. ncbi request reprint The minisequencing method: an alternative strategy for preimplantation genetic diagnosis of single gene disorders
    F Fiorentino
    GENOMA Molecular Genetics Laboratory, via Po nr 102, 00198 Rome
    Mol Hum Reprod 9:399-410. 2003
    ..Its applicability to PGD could be helpful, particularly in cases in which the mutation(s) involved are difficult to assess by restriction analysis or other commonly used methods...
  11. ncbi request reprint Rapid protocol for pre-conception genetic diagnosis of single gene mutations by first polar body analysis: a possible solution for the Italian patients
    F Fiorentino
    EmbryoGen, Centre for Preimplantation Genetic Diagnosis, via Po, Rome, Italy
    Prenat Diagn 28:62-4. 2008
  12. ncbi request reprint Development and clinical application of a strategy for preimplantation genetic diagnosis of single gene disorders combined with HLA matching
    F Fiorentino
    EmbryoGen Centre for Preimplantation Genetic Diagnosis, Rome, Italy
    Mol Hum Reprod 10:445-60. 2004
    ..The major advantage of this approach is that the validation of a single assay can be done once and then used for the majority of the patients, reducing notably time needed for preclinical set-up of each case...
  13. ncbi request reprint Strategies and clinical outcome of 250 cycles of Preimplantation Genetic Diagnosis for single gene disorders
    F Fiorentino
    EmbryoGen Centre for Preimplantation Genetic Diagnosis, GENOMA Molecular Genetics Laboratory, Via Po 102, 00198 Rome, Italy
    Hum Reprod 21:670-84. 2006
    ....
  14. ncbi request reprint Birth of a healthy female after preimplantation genetic diagnosis for Charcot-Marie-Tooth type X
    M Iacobelli
    Reproductive Medicine European Hospital, Rome, Italy
    Reprod Biomed Online 7:558-62. 2003
    ..Two unaffected embryos were transferred, resulting in a singleton pregnancy followed by the birth of a healthy female...