Pio Zeppa

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. ncbi request reprint Morphometry and cytological grading of chondroid tumors
    Pio Zeppa
    Diagn Cytopathol 30:289. 2004
  2. ncbi request reprint Fine needle cytology and flow cytometry of ectopic cervical thymoma: a case report
    Pio Zeppa
    Department of Biomorphological and Functional Sciences, Faculty of Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy
    Acta Cytol 54:998-1002. 2010
  3. doi request reprint Fine needle aspiration cytology and flow cytometry immunophenotyping of non-Hodgkin lymphoma: can we do better?
    P Zeppa
    Dipartimenti di Scienze Biomorfologiche e Funzionali, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italia
    Cytopathology 21:300-10. 2010
  4. ncbi request reprint Flow cytometry phenotypization of thyroidal lymphoid infiltrate and functional status in Hashimoto's thyroiditis
    Pio Zeppa
    Department of Anatomic Pathology and Cytopathology, Faculty of Medicine and Surgery, Universita di Napoli Federico II, Naples, Italy
    Anal Quant Cytol Histol 28:148-56. 2006
  5. ncbi request reprint Pulmonary langerhans cell histiocytosis (histiocytosis X) on bronchoalveolar lavage: a report of 2 cases
    Pio Zeppa
    Department of Anatomic Pathology, Faculty of Medicine and Surgery, University of Naples Federico II, Naples, Italy
    Acta Cytol 51:480-2. 2007
  6. doi request reprint Cytologic, flow cytometry, and molecular assessment of lymphoid infiltrate in fine-needle cytology samples of Hashimoto thyroiditis
    Pio Zeppa
    Department of Pathology, University of Naples Federico II, Naples, Italy
    Cancer 117:174-84. 2009
  7. ncbi request reprint Fine-needle aspiration cytology in the follow-up of Hodgkin lymphoma
    Pio Zeppa
    Dipartimento di Scienze Biomorfologiche e Funzionali, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italia
    Diagn Cytopathol 36:467-72. 2008
  8. doi request reprint Impact of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in lymph nodal and mediastinal lesions: a multicenter experience
    Pio Zeppa
    Dipartimento di Scienze Biomorfologiche e Funzionali, Universita di Napoli Federico II, Napoli, Italia
    Diagn Cytopathol 39:723-9. 2011
  9. ncbi request reprint Fine-needle cytology and flow cytometry immunophenotyping and subclassification of non-Hodgkin lymphoma: a critical review of 307 cases with technical suggestions
    Pio Zeppa
    Dipartimento di Anatomia Patologica e Citopatologia, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Naples, Italy
    Cancer 102:55-65. 2004
  10. ncbi request reprint Fine-needle aspiration biopsy and flow cytometry immunophenotyping of lymphoid and myeloproliferative disorders of the spleen
    Pio Zeppa
    Dipartimento di Anatomia Patologica e Citopatologia, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italy
    Cancer 99:118-27. 2003

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Morphometry and cytological grading of chondroid tumors
    Pio Zeppa
    Diagn Cytopathol 30:289. 2004
  2. ncbi request reprint Fine needle cytology and flow cytometry of ectopic cervical thymoma: a case report
    Pio Zeppa
    Department of Biomorphological and Functional Sciences, Faculty of Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy
    Acta Cytol 54:998-1002. 2010
    ..A case of ectopic cervical thymoma (ECT) in which fine needle cytology (FNC) and flow cytometry (FC) have orientated the cytologic diagnosis, is described...
  3. doi request reprint Fine needle aspiration cytology and flow cytometry immunophenotyping of non-Hodgkin lymphoma: can we do better?
    P Zeppa
    Dipartimenti di Scienze Biomorfologiche e Funzionali, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italia
    Cytopathology 21:300-10. 2010
    ....
  4. ncbi request reprint Flow cytometry phenotypization of thyroidal lymphoid infiltrate and functional status in Hashimoto's thyroiditis
    Pio Zeppa
    Department of Anatomic Pathology and Cytopathology, Faculty of Medicine and Surgery, Universita di Napoli Federico II, Naples, Italy
    Anal Quant Cytol Histol 28:148-56. 2006
    ..To evaluate the thyroidal lymphoid infiltrate (TLI) in thyroidal functional status (TFS) for differences among patients with Hashimoto's thyroiditis (HT)...
  5. ncbi request reprint Pulmonary langerhans cell histiocytosis (histiocytosis X) on bronchoalveolar lavage: a report of 2 cases
    Pio Zeppa
    Department of Anatomic Pathology, Faculty of Medicine and Surgery, University of Naples Federico II, Naples, Italy
    Acta Cytol 51:480-2. 2007
    ..Pulmonary Langerhans cell histiocytosis (PLCH) is an interstitial lung disease characterized by bilateral nodular and cystic lesions. Clinically it seems to be a reactive process related to cigarette smoking...
  6. doi request reprint Cytologic, flow cytometry, and molecular assessment of lymphoid infiltrate in fine-needle cytology samples of Hashimoto thyroiditis
    Pio Zeppa
    Department of Pathology, University of Naples Federico II, Naples, Italy
    Cancer 117:174-84. 2009
    ..The objective of the current study was to classify the TLI in HT by comparing the cytologic features with flow cytometry (FC) data and evaluating the kappa/lambda light chain ratio and its molecular assessment...
  7. ncbi request reprint Fine-needle aspiration cytology in the follow-up of Hodgkin lymphoma
    Pio Zeppa
    Dipartimento di Scienze Biomorfologiche e Funzionali, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italia
    Diagn Cytopathol 36:467-72. 2008
    ..Sensitivity and specificity in assisted FNC are higher than in nonassisted ones. The main advantage of assisted FNC in the follow-up of HL is to produce accurate diagnoses avoiding invasive biopsies...
  8. doi request reprint Impact of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in lymph nodal and mediastinal lesions: a multicenter experience
    Pio Zeppa
    Dipartimento di Scienze Biomorfologiche e Funzionali, Universita di Napoli Federico II, Napoli, Italia
    Diagn Cytopathol 39:723-9. 2011
    ....
  9. ncbi request reprint Fine-needle cytology and flow cytometry immunophenotyping and subclassification of non-Hodgkin lymphoma: a critical review of 307 cases with technical suggestions
    Pio Zeppa
    Dipartimento di Anatomia Patologica e Citopatologia, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Naples, Italy
    Cancer 102:55-65. 2004
    ..The authors present a critical review of 307 lymph nodal and extra lymph nodal lymphoproliferative disorders that were diagnosed with FNC and FC...
  10. ncbi request reprint Fine-needle aspiration biopsy and flow cytometry immunophenotyping of lymphoid and myeloproliferative disorders of the spleen
    Pio Zeppa
    Dipartimento di Anatomia Patologica e Citopatologia, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italy
    Cancer 99:118-27. 2003
    ..Flow cytometry (FC) is a useful adjunct to fine-needle aspiration biopsy (FNAB) in the evaluation of lymphoproliferative disorders. The application of FC to FNAB of the spleen (sFNAB) is reported...
  11. ncbi request reprint Estimation of bulky lymph nodes by power Doppler ultrasound scanning in patients with Hodgkin's lymphoma: a prospective study
    Marco Picardi
    Department of Biochemistry and Medical Biotechnology, Federico II University Medical School, Naples, Italy
    Haematologica 91:960-3. 2006
    ..001). Power Doppler US, a readily available imaging technique, provides a better prognostic classification by detecting true bulky disease more accurately...
  12. doi request reprint Fine-needle cytology and flow cytometry assessment of reactive and lymphoproliferative processes of the breast
    Elena Vigliar
    Dipartimenti di Scienze Biomorfologiche e Funzionali, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italia
    Acta Cytol 56:130-8. 2012
    ..We report an experience with fine-needle cytology (FNAC) combined with flow cytometry (FC) and immunocytochemistry (ICC) in the diagnosis of these processes...
  13. doi request reprint Clonal B-cell population in a reactive lymph node in acquired immunodeficiency syndrome
    Immacolata Cozzolino
    Department of Pathological Anatomy and Cytopathology, University of Naples Federico II, Naples, Italy
    Diagn Cytopathol 37:910-4. 2009
    ..This experience suggests much attention in the evaluation of radiological, cytological, and FC data and in clinical correlation in patients suffering from autoimmune or immunodeficiency syndromes...
  14. ncbi request reprint Expression of NK-associated antigens in extramedullary lymph nodal blast crisis of chronic myeloid leukemia on fine-needle cytology
    Pio Zeppa
    Dipartmento di Anatomia Patologica e Citopatologia, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italia
    Diagn Cytopathol 27:158-60. 2002
    ..This unusual expression, its possible explanation, the related technical problems, and clinicopathological aspects are discussed...
  15. doi request reprint Foamy gland pancreatic ductal adenocarcinoma diagnosed on EUS-FNA: a histochemical, immunohistochemical, and molecular report
    Claudio Bellevicine
    Department of Biomorfologic and Functional Sciences, University of Naples Federico II, Naples, Italy
    Diagn Cytopathol 41:77-80. 2013
    ..The diagnostic interpretation of foamy atypical cells on direct smears may benefit from cell block preparation and from ancillary techniques...
  16. doi request reprint Efficacy and safety of rituximab treatment in patients with progressive transformation of germinal centers after Hodgkin lymphoma in complete remission post-induction chemotherapy and radiotherapy
    Marco Picardi
    Department of Biochemistry and Medical Biotechnology, Federico II University Medical School, Naples, Italy
    Leuk Lymphoma 52:2082-9. 2011
    ..The number needed to treat with rituximab to avoid one Hodgkin lymphoma relapse was four. Our study shows that prophylaxis with rituximab helps improve EFS in patients with PTGC and a history of Hodgkin lymphoma...
  17. doi request reprint Cytological and molecular features of papillary thyroid carcinoma with prominent hobnail features: a case report
    Claudio Bellevicine
    Department of Biomorphologic and Functional Sciences, University of Naples Federico II, Naples, Italy
    Acta Cytol 56:560-4. 2012
    ..Thus, a better patient management might benefit from its early diagnosis on fine needle aspiration (FNA) samples. To date, the FNA cytology of PTC with prominent hobnail features has not been described...
  18. doi request reprint Cytological and histological detection of amyloid deposits in bone marrow of patients affected by multiple myeloma
    Fara Petruzziello
    Hematology, Department of Biochemistry and Medical Biotechnology, University Federico II, Napoli, Italy
    Leuk Lymphoma 52:2304-7. 2011
    ..Should further studies confirm our findings, cytological assessment could be considered a sensitive technique to detect bone marrow amyloid deposits...
  19. doi request reprint Contrast-enhanced harmonic compound US of the spleen to increase staging accuracy in patients with Hodgkin lymphoma: a prospective study
    Marco Picardi
    Departments of Biochemistry and Medical Biotechnology, Histopathology, and Oncology, Federico II University Medical School, and Fondazione SDN, Naples, Italy
    Radiology 251:574-82. 2009
    ....
  20. ncbi request reprint Hemophagocytic histiocytosis diagnosed by fine needle aspiration cytology of the spleen. A case report
    Pio Zeppa
    Dipartimento di Anatomia Patologica, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, via Pansini N 5, 80131 Naples, Italy
    Acta Cytol 48:415-9. 2004
    ..Hemophagocytic histiocytosis (HPS) is an idiopathic, familial or secondary syndrome characterized by mature histiocytes causing intensive erythrophagocytosis...
  21. doi request reprint Cyclin D1 and D3 overexpression predicts malignant behavior in thyroid fine-needle aspirates suspicious for Hurthle cell neoplasms
    Giancarlo Troncone
    Department of Biomorphological and Functional Science, University of Naples Federico II, Naples, Italy
    Cancer 117:522-9. 2009
    ..The authors of this report recently identified cyclin D3 overexpression on histologic sections of Hurthle cell carcinoma. In this study, they assessed the diagnostic value of cyclin D3 immunohistochemistry added to routine cytology...
  22. ncbi request reprint Aggressive papillary male breast carcinoma on fine-needle cytology sample
    Pio Zeppa
    Dipartimento di Anatomia Patologica e Citopatologia, Facolta di Medicina e Chirurgia, Universita di Napoli Federico II, Napoli, Italia
    Diagn Cytopathol 29:360-3. 2003
    ....
  23. ncbi request reprint Lymphnode localization of extramedullary myeloid cell tumor in myelodysplastic syndrome: report of one case diagnosed by fine-needle cytology
    Franco Fulciniti
    Dipartimento di Scienze Biomorfologiche e Funzionali, Sezione di Anatomia Patologica e Citopatologia, Universita degli Studi di Napoli Federico II, Naples, Italy
    Diagn Cytopathol 28:136-9. 2003
    ..Furthermore, the extramedullary myeloid tumor in this case did not significantly affect the response to the chemotherapy of RAEB-t...
  24. ncbi request reprint Randomized comparison of power Doppler ultrasound-directed excisional biopsy with standard excisional biopsy for the characterization of lymphadenopathies in patients with suspected lymphoma
    Marco Picardi
    Department of Clinical and Experimental Medicine, CEINGE Biotecnologie Avanzate, Federico II University Medical School, Naples, Italy
    J Clin Oncol 22:3733-40. 2004
    ..Power Doppler ultrasound (US) helps predict the malignant status of lymphadenopathies. We used power Doppler US to select for biopsy the lymph node most suspected of malignancy...
  25. pmc Foregut duplication of the stomach diagnosed by endoscopic ultrasound guided fine-needle aspiration cytology: case report and literature review
    Vincenzo Napolitano
    Department of General and Specialistic Surgery, School of Medicine, Second University of Naples, 5 S, Pansini Street, 80100, Naples, Italy
    World J Surg Oncol 11:33. 2013
    ..In this case, EUS-guided fine-needle aspiration cytology could provide a cytological diagnosis useful to arrange in advance the more adequate surgical treatment...
  26. ncbi request reprint Cutaneous needle track seeding of mesothelioma diagnosed by fine needle aspiration cytology: a case report
    Jessica Falleti
    Department of Pathology, University of Naples Federico II, Naples, Italy
    Acta Cytol 54:811-4. 2010
    ..Diagnostic and therapeutic procedures for mesothelioma require surgical biopsy or the usage of different-sized needles. Thoracic wall involvement along the surgical or needle tracks has been reported...
  27. ncbi request reprint Occult lymph node metastasis from desmoplastic small round cell tumor diagnosed by fine needle aspiration cytology. A case report
    Pio Zeppa
    Department of Anatomic Pathology and Cytopathology, , , Via Pansini 5, 80131 Naples, Italy
    Acta Cytol 47:501-5. 2003
    ..Because of the tumor's aggressiveness, a rapid and accurate diagnosis is required...
  28. pmc p27Kip1 is expressed in proliferating cells in its form phosphorylated on threonine 187
    Giancarlo Troncone
    Dipartimento di Scienze Biomorfologiche e Funzionali, Facolt di Medicina e Chirurgia, Universit Federico II, Napoli, Italy
    BMC Clin Pathol 5:3. 2005
    ..CONCLUSION: Overall, our data suggest that p27 expression also occurs in proliferating cells compartments and the combined use of both regular and phospho- p27 antibodies is suggested...
  29. pmc Gastric duplication cyst: a rare congenital disease often misdiagnosed in adults
    Jessica Falleti
    Section of Pathology, Department of Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy
    Case Rep Gastrointest Med 2013:850967. 2013
    ..Herein, we report a 55-year-old male with a gastric duplication cyst found on routinely checkup for chronic hepatitis and first misdiagnosed as a gastrointestinal stromal tumor (GIST); we also discuss its embryology...
  30. doi request reprint Cytology-based gene mutation tests to predict response to anti-epidermal growth factor receptor therapy: a review
    Umberto Malapelle
    Dipartimento di Scienze Biomorfologiche e Funzionali, Universita di Napoli Federico II, Naples, Italy
    Diagn Cytopathol 39:703-10. 2011
    ..We argue that the standard of quality of gene mutation tests on cytological samples is closely dependent on the extent of the cytopathologist's involvement...
  31. ncbi request reprint Fine needle aspiration cytology of a cutaneous metastasis from an extraadrenal paraganglioma: a case report
    Immacolata Cozzolino
    Department of Anatomic Pathology and Cytopathology, University of Naples Federico II, Via S Pansini n 5, 80131 Naples, Italy
    Acta Cytol 54:885-8. 2010
    ..Pheochromocytomas/paragangliomas are rare tumors originating from neuroectodermic cells, which metastasize in only 10% of cases...
  32. ncbi request reprint Lymph node and lymphoid organs fine needle aspiration cytology: historical background
    Immacolata Cozzolino
    Dipartimento di Scienze Biomorfologiche e Funzionali, Facolta di Medicina e Chirurgia, Universita Degli Studi Di Napoli, Federico II, Napoli, Italy
    Infez Med 20:8-11. 2012
    ..Moreover, numerous studies have demonstrated that vital cells obtained by FNC are excellent samples suitable for molecular evaluation, offering new challenging application to lymph node FNC...
  33. doi request reprint Multiple metachronus proliferative fasciitis occurring in different anatomic regions: a case report and review of the literature
    Brigida Stanzione
    Department of Oncology, University of Naples Federico II, Naples, Italy
    Pathol Res Pract 208:126-30. 2012
    ....
  34. doi request reprint UbcH10 expression in human lymphomas
    Giancarlo Troncone
    Dipartimento di Scienze Biomorfologiche e Funzionali, University of Naples Federico II, Napoli, Italy
    Histopathology 54:731-40. 2009
    ..We have previously reported that UbcH10 overexpression is associated with aggressive thyroid, ovarian and breast carcinomas. The aim of this study was to investigate UbcH10 expression in human lymphomas...
  35. ncbi request reprint Malignant fibrous histiocytoma of the stomach
    Valentina Accattatis
    Department of Biomorphological and Functional Sciences, Service of Radiology, University Federico II of Naples, Naples, Italy
    Radiol Med 106:481-5. 2003
    ..Our case shows some differences from the others described in literature: the sight of mass, the age of the patient, the extension at the moment of the diagnosis...
  36. ncbi request reprint Lymph nodes Fine Needle Cytology in the diagnosis of infectious diseases: cytological and histological correlations
    Immacolata Cozzolino
    Dipartimento di Scienze Biomorfologiche e Funzionali, Universita degli Studi di Napoli Federico II, Istituto Nazionale dei Tumori, Fondazione G Pascale, Napoli, Italy
    Infez Med 20:16-20. 2012
    ..Lymph nodal FNC should be performed by expert cytopathologists ensuring a safe and correct execution and a rapid evaluation of the smears for the assessment and the application of specific ancillary techniques...
  37. ncbi request reprint Lymph node fine needle cytology in the diagnosis of infectious diseases and reactive unspecific processes
    Ciro Cipullo
    Dipartimento di Scienze Biomorfologiche e Funzionali, Facolta di Medicina e Chirurgia, Universita degli Studi di Napoli Federico II, Napoli, Italy
    Infez Med 20:30-3. 2012
    ..This study reports the use of FNC in the diagnosis of reactive lymph nodes in infectious diseases, exploring possibilities and limitations of the technique in this specific clinical setting...
  38. doi request reprint Amyloid in bone marrow smears of patients affected by multiple myeloma
    Fara Petruzziello
    Hematology, Department of Biochemistry and Medical Biotechnology, University Federico II, Naples, Italy
    Ann Hematol 89:469-74. 2010
    ..Further studies and prolonged follow-up are needed to validate our findings and to define possible prognostic aspects...
  39. ncbi request reprint Fine needle aspiration biopsy of hepatic focal fatty change. A report of two cases
    Pio Zeppa
    Department of Anatomic Pathology and Cytopathology, Faculty of Medicine and Surgery, Universita di Napoli Federico II, Via Pansini 5, 80131 Naples, Italy
    Acta Cytol 46:567-70. 2002
    ..The ultrasonographic and computed tomographic patterns are those of an isointense or hyperechoic nodule, sometimes simultating metastasis...
  40. pmc Thyroid B-flow twinkling sign: a new feature of papillary cancer
    Luca Brunese
    Department of Health Science, Chair of Radiology, University of Molise, Campobasso, Italy
    Eur J Endocrinol 159:447-51. 2008
    ..Using B-flow imaging (BFI), we identified a new sign (the twinkling sign; BFI-TS) in 'suspect' PTC nodules, which appeared to be generated by microcalcifications...
  41. ncbi request reprint Ultrasound-guided fine needle aspiration cytology combined with flow cytometric immunophenotyping for rapid characterization of deep-seated non-Hodgkin's lymphoma recurrence
    Marco Picardi
    Haematologica 88:356-8. 2003
  42. ncbi request reprint Morphometric evaluation of thyrostatic treatment on thyreocytes in nodular goiter on cytologic samples
    Pio Zeppa
    Anal Quant Cytol Histol 27:118-9. 2005