Research TopicsGenomes and GenesSpecies | Salvatore SorrentinoSummaryAffiliation: Federico II University Country: Italy Publications
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Detail Information
Publications
Degradation of double-stranded RNA by human pancreatic ribonuclease: crucial role of noncatalytic basic amino acid residuesSalvatore Sorrentino
Department of Biological Chemistry, University Federico II of Naples, Naples, Italy
Biochemistry 42:10182-90. 2003..These data and the wide distribution of the enzyme in different organs and body fluids suggest that HP-RNase has evolved to perform both digestive and nondigestive physiological functions...
The eight human "canonical" ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteinsSalvatore Sorrentino
Department of Structural and Functional Biology, University of Naples Federico II, Naples, Italy
FEBS Lett 584:2194-200. 2010..Recent evolutionary studies suggest that RNases started off in vertebrates as host defence or angiogenic proteins...
On the thermal stability of the two dimeric forms of ribonuclease AEnrico Bucci
Istituto di Biostrutture e Bioimmagini, CNR, Via Mezzocannone 6, I-80134 Napoli, Italy
Biophys Chem 116:89-95. 2005..This finding is correlated to the structural features of the so-called open interface of the dimeric forms...
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitorMariarosaria Naddeo
Dipartimento di Biologia Strutturale e Funzionale, , Italy
FEBS Lett 579:2663-8. 2005..However, when the interactions of the two cytotoxic RNase A dimers with cRI were investigated in a quantitative fashion and at the molecular level, the dimers were found to bind cRI with high affinity and to form tight complexes...
