Paola Di Natale

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. ncbi Analysis of Sanfilippo A gene mutations in a large pedigree
    P Di Natale
    Dipartimento di Biochimica e Biotecnologie Mediche, University of Naples Federico II, Italy
    Clin Genet 63:314-8. 2003
  2. ncbi Treatment of the mouse model of mucopolysaccharidosis type IIIB with lentiviral-NAGLU vector
    Paola Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Via S Pansini n 5, 80131 Naples, Italy
    Biochem J 388:639-46. 2005
  3. ncbi Gene symbol: SGSH. Disease: Sanfilippo type A syndrome, mucopolysaccharidosis IIIA
    P Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Italy
    Hum Genet 119:679. 2006
  4. ncbi Molecular markers for the follow-up of enzyme-replacement therapy in mucopolysaccharidosis type VI disease
    Paola Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Naples, Italy
    Biotechnol Appl Biochem 49:219-23. 2008
  5. ncbi Serum MIP-1 alpha level: a biomarker for the follow-up of lentiviral therapy in mucopolysaccharidosis IIIB mice
    Paola Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Via Sergio Pansini n 5, 80131 Naples, Italy
    J Inherit Metab Dis 33:159-65. 2010

Collaborators

Detail Information

Publications5

  1. ncbi Analysis of Sanfilippo A gene mutations in a large pedigree
    P Di Natale
    Dipartimento di Biochimica e Biotecnologie Mediche, University of Naples Federico II, Italy
    Clin Genet 63:314-8. 2003
    ..This study places R433Q as a severe mutation underlying Sanfilippo A disease...
  2. ncbi Treatment of the mouse model of mucopolysaccharidosis type IIIB with lentiviral-NAGLU vector
    Paola Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Via S Pansini n 5, 80131 Naples, Italy
    Biochem J 388:639-46. 2005
    ..Interestingly, the decrease in GAG levels was maintained in liver, spleen, lung and heart of treated mice. These results show the promising potential and the limitations of lentiviral-NAGLU vector to deliver the human NAGLU gene in vivo...
  3. ncbi Gene symbol: SGSH. Disease: Sanfilippo type A syndrome, mucopolysaccharidosis IIIA
    P Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Italy
    Hum Genet 119:679. 2006
  4. ncbi Molecular markers for the follow-up of enzyme-replacement therapy in mucopolysaccharidosis type VI disease
    Paola Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Naples, Italy
    Biotechnol Appl Biochem 49:219-23. 2008
    ..In addition to its role as a potential biomarker, TNFalpha expression could provide insights into the possible pathophysiological mechanisms underlying the mucopolysaccharidoses...
  5. ncbi Serum MIP-1 alpha level: a biomarker for the follow-up of lentiviral therapy in mucopolysaccharidosis IIIB mice
    Paola Di Natale
    Department of Biochemistry and Medical Biotechnologies, University of Naples Federico II, Via Sergio Pansini n 5, 80131 Naples, Italy
    J Inherit Metab Dis 33:159-65. 2010
    ..Our studies suggest MIP-1alpha as the first serum biomarker that could be used to monitor disease progression and treatment for MPS IIIB disease...