Luigi Insabato

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. doi request reprint Coexistence of primary gastric giant cell-rich leiomyosarcoma and gastrointestinal stromal tumor: report of a very rare combination and review of the literature
    Luigi Insabato
    Department of Pathology, Faculty of Medicine, University Federico II, Via S Pansini 5, 80131 Naples, Italy
    Int J Surg Pathol 20:74-8. 2012
  2. ncbi request reprint Malignant gastrointestinal leiomyosarcoma and gastrointestinal stromal tumor with prominent osteoclast-like giant cells
    Luigi Insabato
    Dipartimento di Anatomia Patologica, Facolta di Medicina, Universita Federico II, Napoli, Italy
    Arch Pathol Lab Med 128:440-3. 2004
  3. ncbi request reprint Renal metastasis from thyroid carcinoma 35 years after detection of the primary tumor
    Luigi Insabato
    Department of Pathology, Faculty of Medicine, Federico II University, Naples, Italy
    Tumori 89:99-101. 2003
  4. ncbi request reprint Primary intramuscular infestation of Echinococcus granulosus misdiagnosed as a soft tissue tumor: a case report
    Luigi Insabato
    Section of Pathology, Department of Biomorphological and Functional Sciences, University of Naples Federico II, Naples, Italy
    Acta Cytol 51:631-3. 2007
  5. doi request reprint Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases
    L Insabato
    Department of Anatomic Pathology, University Federico II, Naples, Italy
    Int J Surg Pathol 17:250-4. 2009
  6. ncbi request reprint Primary monotypic epithelioid angiomyolipoma of bone
    L Insabato
    Dipartimento di Anatomia Patologica, Facolta di Medicina, Universita Federico II, Napoli, Italy
    Histopathology 40:286-90. 2002
  7. ncbi request reprint Primary Kaposi sarcoma of the bowel in a HIV-negative patient
    L Insabato
    Department of Anatomic Pathology, School of Medicine, Federico II, University of Naples, Naples, Italy
    J Surg Oncol 76:197-200. 2001
  8. ncbi request reprint Pathology of neuroendocrine tumours
    Luigi Insabato
    Department of Biomorphological and Functional Science, Section of Anatomic Pathology, University Federico II of Naples, Faculty of Medicine, Naples, Italy
    Front Biosci (Landmark Ed) 14:4712-8. 2009
  9. ncbi request reprint Clinicopathologic and immunohistochemical study of surgically treated primary gastric MALT lymphoma
    Luigi Insabato
    Department of Anatomic Pathology, School of Medicine, Federico II University of Naples, Naples, Italy
    J Surg Oncol 83:106-11. 2003
  10. pmc Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours
    Dolores Di Vizio
    Department of Functional and Biomorphological Science, University Federico II, Naples, Italy
    BMC Cancer 8:134. 2008

Collaborators

Detail Information

Publications48

  1. doi request reprint Coexistence of primary gastric giant cell-rich leiomyosarcoma and gastrointestinal stromal tumor: report of a very rare combination and review of the literature
    Luigi Insabato
    Department of Pathology, Faculty of Medicine, University Federico II, Via S Pansini 5, 80131 Naples, Italy
    Int J Surg Pathol 20:74-8. 2012
    ..The patient was alive with no evidence of recurrence 10 months later. To the authors' knowledge, this association has not been previously reported...
  2. ncbi request reprint Malignant gastrointestinal leiomyosarcoma and gastrointestinal stromal tumor with prominent osteoclast-like giant cells
    Luigi Insabato
    Dipartimento di Anatomia Patologica, Facolta di Medicina, Universita Federico II, Napoli, Italy
    Arch Pathol Lab Med 128:440-3. 2004
    ..One case of leiomyosarcoma and one case of gastrointestinal stromal tumor with prominent osteoclast-like giant cells have so far been reported in the digestive tract...
  3. ncbi request reprint Renal metastasis from thyroid carcinoma 35 years after detection of the primary tumor
    Luigi Insabato
    Department of Pathology, Faculty of Medicine, Federico II University, Naples, Italy
    Tumori 89:99-101. 2003
    ..The possibility of a secondary tumor should always be considered in the differential diagnosis of renal neoplasms, even when the tumor is a large, unilateral, solitary renal mass...
  4. ncbi request reprint Primary intramuscular infestation of Echinococcus granulosus misdiagnosed as a soft tissue tumor: a case report
    Luigi Insabato
    Section of Pathology, Department of Biomorphological and Functional Sciences, University of Naples Federico II, Naples, Italy
    Acta Cytol 51:631-3. 2007
    ..The occurrence of a primary intramuscular infestation of Echinococcus granulosus is extremely rare...
  5. doi request reprint Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases
    L Insabato
    Department of Anatomic Pathology, University Federico II, Naples, Italy
    Int J Surg Pathol 17:250-4. 2009
    ..All of the tumors were strongly positive for CD34, and 3 of them expressed high levels of progesterone receptor. Solitary fibrous tumors are fairly rare, occurring in many parts of the body, and their behavior is unpredictable...
  6. ncbi request reprint Primary monotypic epithelioid angiomyolipoma of bone
    L Insabato
    Dipartimento di Anatomia Patologica, Facolta di Medicina, Universita Federico II, Napoli, Italy
    Histopathology 40:286-90. 2002
    ..Angiomyolipoma, including its morphological variants, belongs to the family of perivascular epithelioid cell tumour...
  7. ncbi request reprint Primary Kaposi sarcoma of the bowel in a HIV-negative patient
    L Insabato
    Department of Anatomic Pathology, School of Medicine, Federico II, University of Naples, Naples, Italy
    J Surg Oncol 76:197-200. 2001
    ..PCR analysis of the tumor showed positivity for human herpesvirus 8. Two of the six reported cases of Kaposi sarcoma limited to the bowel were from African men before the AIDS epidemic. J. Surg. Oncol. 2001;76:197-200...
  8. ncbi request reprint Pathology of neuroendocrine tumours
    Luigi Insabato
    Department of Biomorphological and Functional Science, Section of Anatomic Pathology, University Federico II of Naples, Faculty of Medicine, Naples, Italy
    Front Biosci (Landmark Ed) 14:4712-8. 2009
    ..Recent technical improvements, have increased the rate of detection, and have contributed to better diagnosis and classification of these tumors...
  9. ncbi request reprint Clinicopathologic and immunohistochemical study of surgically treated primary gastric MALT lymphoma
    Luigi Insabato
    Department of Anatomic Pathology, School of Medicine, Federico II University of Naples, Naples, Italy
    J Surg Oncol 83:106-11. 2003
    ..Immunohistochemical expression of p53, bcl-2, and Ki67 and Helicobacter pylori (Hp) infection was evaluated, along with a correlation with clinical outcome...
  10. pmc Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours
    Dolores Di Vizio
    Department of Functional and Biomorphological Science, University Federico II, Naples, Italy
    BMC Cancer 8:134. 2008
    ..The aim of our study was to investigate the role of morphologic parameters and expression of cells cycle regulators as prognosticators in GIST...
  11. doi request reprint The levels of the endocannabinoid receptor CB2 and its ligand 2-arachidonoylglycerol are elevated in endometrial carcinoma
    Maurizio Guida
    Department of Gynecology and Obstetrics and Pathophysiology of Human Reproduction, University of Naples Federico II, 80078 Naples, Italy
    Endocrinology 151:921-8. 2010
    ..In conclusion, the endocannabinoid system seems to play an important role in human endometrial carcinoma, and modulation of CB(2) activity/expression may account for a tumor-suppressive effect...
  12. doi request reprint Immunophenotyping analysis in invasive micropapillary carcinoma of the breast: role of CD24 and CD44 isoforms expression
    Sara Simonetti
    Department of Functional and Biomorphological Science, University Federico II, Via S Pansini 5, 80131 Naples, Italy
    Breast 21:165-70. 2012
    ..These features could explain the high lymph-vascular invasion propensity and higher metastatic capability of these tumors and could be a useful tool for a future targeted therapy...
  13. pmc Prognostic value of p27Kip1 expression in Basaloid Squamous Cell Carcinoma of the larynx
    Grazia Salerno
    Department of Otolaryngology, University Federico II, Naples, Italy
    BMC Cancer 6:146. 2006
    ..Up to date the role of this protein was never studied in BSCC. Aim of our study was to investigate the potential prognostic value of p27kip1 levels and their correlation with Ki67/Mib-1 and p53 expression in BSCC of the larynx...
  14. ncbi request reprint Ovarian metastasis from renal cell carcinoma: a report of three cases
    Luigi Insabato
    Department of Anatomic Pathology, Faculty of Medicine, University of Naples Federico II, Naples, Italy
    Int J Surg Pathol 11:309-12. 2003
    ..To the best of our knowledge only 11 cases of clinically detected ovarian metastases of RCC have been reported. We report 3 new cases and review the literature on the subject...
  15. doi request reprint Signet-ring-cell carcinoma of stomach metastatic to the bladder: a case report with cytological and histological correlation and literature review
    Elena Vigliar
    University Federico II of Naples, Naples, Italy
    Int J Surg Pathol 21:72-5. 2013
    ..Bladder involvement by a secondary tumor is fairly rare and an uncommon source of bladder metastasis is the stomach...
  16. doi request reprint Symplastic glomus tumor: report of a challenging lesion with literature review
    Jessica Falleti
    Department of Biomorphological and Functional Science, Section of Anatomic Pathology, Federico II University, Naples, Italy
    Pathol Res Pract 208:372-5. 2012
    ..Physicians must be aware of this morphological variation of glomus tumor to avoid the mistake of malignancy, which results in over-treatment of the patient...
  17. pmc Calcitonin-producing well-differentiated neuroendocrine carcinoma (carcinoid tumor) of the urinary bladder: case report
    Massimo Mascolo
    Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples Federico II, Italy
    BMC Cancer 5:88. 2005
    ..The occurrence of calcitonin-secreting primary carcinoid tumor of the urinary bladder is extremely rare...
  18. ncbi request reprint Nodal and extranodal soft tissue polymorphous hemangioendothelioma: a case report and review of the literature
    Jessica Falleti
    Department of Biomorphological and Functional Sciences, Pathology Section, Federico II University, Naples, Italy
    Tumori 95:94-7. 2009
    ..Polymorphous hemangioendothelioma is a rare vascular tumor of borderline malignant potential and only 10 cases have been described in the literature so far...
  19. doi request reprint Role of polysomy 17 in transitional cell carcinoma of the bladder: immunohistochemical study of HER2/neu expression and fish analysis of c-erbB-2 gene and chromosome 17
    Sara Simonetti
    Department of Biomorphological and Functional Sciences, University Federico II of Naples, Naples, Italy
    Int J Surg Pathol 17:198-205. 2009
    ....
  20. ncbi request reprint Aggressive cemento-ossifying fibroma of the jaws
    A Zupi
    Department of Maxillofacial Surgery, School of Medicine and Surgery, Federico II University of Naples, Italy
    Oral Oncol 36:129-33. 2000
    ..There are, however, diverging features warranting separation of different forms. These mild differences may be detected during preoperative assessment of the lesion, allowing a diagnosis of aggressive form to be made...
  21. ncbi request reprint Ovarian metastasis following gallbladder carcinoma: a case report
    C Carlomagno
    Department of Endocrinology and Molecular and Clinical Oncology, Federico II University, Naples, Italy
    Eur J Gynaecol Oncol 31:219-21. 2010
    ..Most metastatic ovarian tumors originate from the gastrointestinal tract, mainly colorectal, gastric, pancreatic; the gallbladder is a very rare source of ovarian metastases...
  22. doi request reprint Radiofrequency-assisted partial nephrectomy for metanephric adenoma: a case report and literature review
    Giovanni Conzo
    Department of Anaesthesiologic, Surgical, and Emergency Science, Second University of Naples, Naples, Italy
    Surg Innov 20:55-8. 2013
    ..PN represents the standard of care for small exophytic MA, and RF-assisted procedures allow an excellent hemostasis and a rapid conservative resection, with very low morbidity...
  23. doi request reprint Endoplasmic reticulum stress is activated in endometrial adenocarcinoma
    Giuseppe Bifulco
    Department of Obstetrics and Gynecology, University Federico II, Naples, Italy
    Gynecol Oncol 125:220-5. 2012
    ..However, a possible role of ER stress and GRP78 in endometrial cancer has never been investigated...
  24. doi request reprint Unexpected autoptic finding in a sudden death: gossypiboma
    Jessica Falleti
    Department of Biomorphological and Functional Science, University Federico II of Naples, Via S Pansini, 5, 80131 Naples, Italy
    Forensic Sci Int 199:e23-6. 2010
    ..All the operators of the surgical team should keep in mind this terrible complication to avoid unpleasant consequences to patient and themselves...
  25. pmc PTPD1 supports receptor stability and mitogenic signaling in bladder cancer cells
    Annalisa Carlucci
    Dipartimento di Biologia e Patologia Molecolare e Cellulare, Universita Federico II, Naples, Italy
    J Biol Chem 285:39260-70. 2010
    ..These findings identify PTPD1 as a novel component of the endocytic machinery that impacts on EGF receptor stability and on growth and motility of bladder cancer cells...
  26. ncbi request reprint Massive infarction of papillary carcinoma of the kidney after fine needle aspiration biopsy: report of a case with cytohistologic correlation
    Franco Fulciniti
    Section of Cytodiagnostics, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy
    Acta Cytol 50:563-6. 2006
    ..Papillary carcinomas are rare malignant tumors of the kidney that sometimes are diagnosed preoperatively from their characteristic computed tomography appearance...
  27. ncbi request reprint Small cell neuroendocrine cervical carcinoma with 1-year follow-up: case report and review
    Giuseppe Bifulco
    Department of Gynecology and Obstetrics, and Pathophysiology, Pathology Section, University of Naples Federico II, Italy
    Anticancer Res 29:477-84. 2009
    ..There is no unanimous opinion regarding the optimal management strategy...
  28. ncbi request reprint Primary intraosseous cavernous hemangioma of the metacarpal bone: a very rare entity. Case report
    Sara Simonetti
    Department of Biomorphological and Functional Sciences, Pathology Section, Federico II University, Naples, Italy
    Tumori 95:101-3. 2009
    ..We report a case of this neoplasm in the distal epiphysis of the third metacarpal bone in a 68-year-old man, along with the clinicopathological findings. The differential diagnosis and a review of the literature are discussed...
  29. doi request reprint Cystic variant of endometrial stromal sarcoma: report of two cases
    Anna Somma
    Department of Biomophological and Functional Science, University Federico II, Naples, Italy
    Int J Surg Pathol 21:278-81. 2013
    ..The differential diagnosis among multicystic endometrial stromal sarcoma and cystic uterine tumors might be very difficult...
  30. pmc Targeting Axl with an high-affinity inhibitory aptamer
    Laura Cerchia
    Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, Naples, Italy
    Mol Ther 20:2291-303. 2012
    ..In this respect, the GL21.T aptamer represents a promising therapeutic molecule for Axl-dependent cancers whose importance is highlighted by the paucity of available Axl-specific inhibitory molecules...
  31. ncbi request reprint Solid-pseudopapillary tumor of the pancreas: a neoplasm with distinct and highly characteristic cytological features
    Guido Pettinato
    Department of Biomorphological and Functional Sciences, Section of Pathology, Faculty of Medicine, University of Naples Federico II, Naples, Italy
    Diagn Cytopathol 27:325-34. 2002
    ....
  32. ncbi request reprint Duodenal epithelioid angiosarcoma: immunohistochemical and clinical findings. A case report
    Chiara Mignogna
    Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples Federico II, Naples, Italy
    Tumori 93:619-21. 2007
    ..The patient died eight months after the diagnosis. Epithelioid angiosarcoma is an aggressive variant of angiosarcoma and must be considered in the differential diagnosis of gastrointestinal tumors...
  33. ncbi request reprint Malignant melanoma in a seagull (Larus fuscus): morphological and immunohistochemical approach
    Alessandro Costagliola
    Department of Pathology and Animal Health, University of Naples Federico II, Via Delpino, 1 80137 Naples, Italy
    Avian Dis 55:147-50. 2011
    ..This is the first case of malignant melanoma described in a seagull, and herein we compare the characteristics of the present case with malignant melanoma already described in domestic animals...
  34. doi request reprint Bone turnover and the osteoprotegerin-RANKL pathway in tumor-induced osteomalacia: a longitudinal study of five cases
    Domenico Rendina
    Department of Clinical and Experimental Medicine, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy
    Calcif Tissue Int 85:293-300. 2009
    ..The BMD increase during TIO treatment is related to the improvement of phosphate rather than FGF-23 levels. A "hungry bone"-like syndrome was observed after surgical or pharmacological treatment...
  35. doi request reprint Selective CB2 up-regulation in women affected by endometrial inflammation
    Teresa Iuvone
    Endocannabinoid Research Group, Department of Experimental Pharmacology, Faculty of Pharmacy, University of Naples, Federico II, Naples, Italy
    J Cell Mol Med 12:661-70. 2008
    ..In conclusion, we believe that the selective CB(2) up-regulation might play a role as a novel prognostic factor in endometrial inflammation...
  36. ncbi request reprint Hyperthyroidism due to coexistence of Graves' disease and Struma ovarii
    Maria G Chiofalo
    Department of Surgical Oncology, National Cancer Institute, Naples, Italy
    Endocr Pract 13:274-6. 2007
    ..To report an unusual case of persistent thyrotoxicosis after treatment of Graves' disease, because of coexistence of struma ovarii...
  37. ncbi request reprint Rare diffuse peritoneal malignant neoplasms: CT findings in two cases
    P P Mainenti
    IBB CNR, Naples, Italy
    Abdom Imaging 28:827-30. 2003
    ..The computed tomographic appearances of two cases of rare peritoneal tumors, epithelioid hemangioendothelioma and desmoplastic small round cell tumor, are described...
  38. ncbi request reprint Fine needle aspiration cytology of desmoplastic small round cell tumor. A case report
    L Insabato
    Department of Pathology, University of Naples Federico II, Italy
    Acta Cytol 43:641-6. 1999
    ..FNA cytology is an effective means of diagnosing deeply located lesions. The cytologic features of DSRCT need to become familiar to pathologists and must be considered in the differential diagnosis of liver metastasis...
  39. ncbi request reprint Sarcomatoid carcinoma of the colon: a case report with literature review
    D Di Vizio
    Department of Anatomical Pathology, II Policlinico, Federico II University, Naples, Italy
    Tumori 87:431-5. 2001
    ..We report a case of primary colonic SC. Both morphological and immunohistochemical analyses are provided along with an evaluation of the unusual clinical history, therapeutic implications, and controversial differential diagnosis...
  40. ncbi request reprint Primary signet-ring cell carcinoma of the uterine cervix with long term follow-up: case report
    L Insabato
    Department of Biomorphologic and Functional Sciences, Pathology Section, University of Naples Federico II, Naples, Italy
    Eur J Gynaecol Oncol 28:411-4. 2007
    ..No previous case of primary pure endocervical SRCA with follow-up longer than three years has been found in the literature...
  41. ncbi request reprint Huge primary retroperitoneal mucinous cystadenoma of borderline malignancy mimicking an ovarian mass: case report and review
    G Bifulco
    Department of Gynecology and Obstetrics, University of Naples Federico II, Naples, Italy
    Anticancer Res 28:2309-15. 2008
    ..1 cm). There is no unanimous opinion on the genesis of these tumors and, due to their extreme rarity, its histogenesis, biological behavior and the optimal management strategy remain at a speculative level...
  42. doi request reprint Extraskeletal chondroma of the masseter muscle: a case report with review of the literature
    J Falleti
    Department of Biomorphological and Functional Science, Section of Anatomic Pathology, Federico II University, Via S Pansini 5, Naples, Italy
    Int J Oral Maxillofac Surg 38:895-9. 2009
    ..The literature on head and neck soft tissue chondroma is also reviewed. To the authors' knowledge, this is the first case of muscular soft tissue chondroma in the head and neck region...
  43. ncbi request reprint Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study
    Regine Schneider-Stock
    Department of Pathology, Otto von Guericke University Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany
    Clin Cancer Res 11:638-45. 2005
    ..P16 loss is a common molecular abnormality in GISTs and might be used in routine diagnosis to identify patients with high-risk tumors...
  44. ncbi request reprint Colonic carcinosarcoma
    Giovanni Conzo
    J Gastroenterol Hepatol 18:748-9. 2003
  45. doi request reprint Chromosomal instability in gastric mucosa-associated lymphoid tissue lymphomas: a fluorescent in situ hybridization study using a tissue microarray approach
    Barbara Bernasconi
    Department of Human Morphology, Section of Human Pathology, University of Insubria, 21100 Varese, Italy
    Hum Pathol 39:536-42. 2008
    ..Our results point out that t(11;18) and aneuploidy may be both involved in lymphomagenesis and that at least a subset of MALT lymphomas may progress toward high-grade neoplasia...
  46. ncbi request reprint Systemic amyloidosis: the CT sign of splenic hypoperfusion
    Pier Paolo Mainenti
    Amyloid 11:281-2. 2004
  47. ncbi request reprint Desmoplastic small round cell tumor
    Luigi Insabato
    Acta Cytol 46:612; author reply 612. 2002
  48. ncbi request reprint Can the situation be reversed? Can the hysteroscopist be more helpful than the pathologist in differentiating atypical hyperplasia and endometrial carcinoma?
    Stefano Bettocchi
    J Minim Invasive Gynecol 13:587-8; author reply 589-90. 2006