Mario Capasso

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. pmc Impact of interleukin-6 -174 G>C gene promoter polymorphism on neuroblastoma
    Francesca Totaro
    Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita degli Studi di Napoli Federico II, Naples, Italy CEINGE Biotecnologie Avanzate, Naples, Italy
    PLoS ONE 8:e76810. 2013
  2. pmc Replication of GWAS-identified neuroblastoma risk loci strengthens the role of BARD1 and affirms the cumulative effect of genetic variations on disease susceptibility
    Mario Capasso
    Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita degli Studi di Napoli Federico II, Naples, Italy
    Carcinogenesis 34:605-11. 2013
  3. doi Genetics and genomics of neuroblastoma
    Mario Capasso
    CEINGE Advanced Biotechnologies, University of Naples Federico II, Naples, Italy
    Cancer Treat Res 155:65-84. 2010
  4. doi SOCS3 and IRS-1 gene expression differs between genotype 1 and genotype 2 hepatitis C virus-infected HepG2 cells
    Marcello Persico
    Internal Medicine and Hepatology Unit, Second University of Naples, Naples, Italy
    Clin Chem Lab Med 47:1217-25. 2009
  5. doi Adiponectin oligomerization state and adiponectin receptors airway expression in chronic obstructive pulmonary disease
    Aurora Daniele
    CEINGE Biotecnologie Avanzate scarl, Naples, Italy
    Int J Biochem Cell Biol 44:563-9. 2012
  6. doi A predicted functional single-nucleotide polymorphism of bone morphogenetic protein-4 gene affects mRNA expression and shows a significant association with cutaneous melanoma in Southern Italian population
    Mario Capasso
    CEINGE Biotecnologie Avanzate, Naples, Italy
    J Cancer Res Clin Oncol 135:1799-807. 2009
  7. doi Mannose-binding lectin genetic analysis: possible protective role of the HYPA haplotype in the development of recurrent urinary tract infections in men
    Olga Scudiero
    Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita di Napoli Federico II, Napoli, Italy CEINGE Biotecnologie Avanzate, Napoli, Italy Electronic address
    Int J Infect Dis 19:100-2. 2014
  8. ncbi Combinations of genetic data in a study of neuroblastoma risk genotypes
    Mario Capasso
    Department of Molecular Medicine and Medical Biotechnologies, University of Napoli Federico II, Naples, Italy CEINGE Centro Ingegneria Genetica Advanced Biotechnologies, Naples, Italy
    Cancer Genet 207:94-7. 2014
  9. pmc Galectin-1 and its involvement in hepatocellular carcinoma aggressiveness
    Daniela Spano
    CEINGE Biotecnologie Avanzate, Naples, Italy
    Mol Med 16:102-15. 2010
  10. doi Pediatric pharmacogenetic and pharmacogenomic studies: the current state and future perspectives
    Roberta Russo
    Department of Biochemistry and Medical Biotechnologies, University Federico II of Naples and CEINGE Biotecnologie Avanzate, Via Gaetano Salvatore 486, Naples, Italy
    Eur J Clin Pharmacol 67:17-27. 2011

Collaborators

Detail Information

Publications14

  1. pmc Impact of interleukin-6 -174 G>C gene promoter polymorphism on neuroblastoma
    Francesca Totaro
    Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita degli Studi di Napoli Federico II, Naples, Italy CEINGE Biotecnologie Avanzate, Naples, Italy
    PLoS ONE 8:e76810. 2013
    ..The genotype GG of single nucleotide polymorphism (SNP) rs1800795 (-174 G>C) in interleukin (IL)-6 promoter has been associated with lower survival of high-risk NB...
  2. pmc Replication of GWAS-identified neuroblastoma risk loci strengthens the role of BARD1 and affirms the cumulative effect of genetic variations on disease susceptibility
    Mario Capasso
    Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita degli Studi di Napoli Federico II, Naples, Italy
    Carcinogenesis 34:605-11. 2013
    ..This study shows that even in the absence of interaction the combination of several low-penetrance alleles has potential to distinguish subgroups of patients at different risks of developing NB...
  3. doi Genetics and genomics of neuroblastoma
    Mario Capasso
    CEINGE Advanced Biotechnologies, University of Naples Federico II, Naples, Italy
    Cancer Treat Res 155:65-84. 2010
    ..Looking forward, a major challenge will be to understand how inherited genetic variation and acquired somatic alterations in the tumor genome interact to exact phenotypic differences in neuroblastoma, and cancer in general...
  4. doi SOCS3 and IRS-1 gene expression differs between genotype 1 and genotype 2 hepatitis C virus-infected HepG2 cells
    Marcello Persico
    Internal Medicine and Hepatology Unit, Second University of Naples, Naples, Italy
    Clin Chem Lab Med 47:1217-25. 2009
    ..The goal of this study was to clarify the role of genotype 1b and 2 in the genetic expression of suppressor of cytokine signaling 3 (SOCS3) and insulin receptor substrate 1 (IRS-1)...
  5. doi Adiponectin oligomerization state and adiponectin receptors airway expression in chronic obstructive pulmonary disease
    Aurora Daniele
    CEINGE Biotecnologie Avanzate scarl, Naples, Italy
    Int J Biochem Cell Biol 44:563-9. 2012
    ..Thus, total Acrp30, HMW and its receptors could be considered critical targets to improve diagnostic and therapeutic strategies for lung diseases...
  6. doi A predicted functional single-nucleotide polymorphism of bone morphogenetic protein-4 gene affects mRNA expression and shows a significant association with cutaneous melanoma in Southern Italian population
    Mario Capasso
    CEINGE Biotecnologie Avanzate, Naples, Italy
    J Cancer Res Clin Oncol 135:1799-807. 2009
    ..We performed an association study to investigate the effect of putative functional single nucleotide polymorphisms (SNPs) of BMP4 on development of cutaneous melanoma (CM)...
  7. doi Mannose-binding lectin genetic analysis: possible protective role of the HYPA haplotype in the development of recurrent urinary tract infections in men
    Olga Scudiero
    Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Universita di Napoli Federico II, Napoli, Italy CEINGE Biotecnologie Avanzate, Napoli, Italy Electronic address
    Int J Infect Dis 19:100-2. 2014
    ..05). Our data indicate that the HYPA haplotype in the MBL2 gene could be associated with a minor risk of developing rUTI in males. ..
  8. ncbi Combinations of genetic data in a study of neuroblastoma risk genotypes
    Mario Capasso
    Department of Molecular Medicine and Medical Biotechnologies, University of Napoli Federico II, Naples, Italy CEINGE Centro Ingegneria Genetica Advanced Biotechnologies, Naples, Italy
    Cancer Genet 207:94-7. 2014
    ..Among the latter, a cluster of 24 combinations was found to be significantly associated with NB (P < 0.00001)...
  9. pmc Galectin-1 and its involvement in hepatocellular carcinoma aggressiveness
    Daniela Spano
    CEINGE Biotecnologie Avanzate, Naples, Italy
    Mol Med 16:102-15. 2010
    ....
  10. doi Pediatric pharmacogenetic and pharmacogenomic studies: the current state and future perspectives
    Roberta Russo
    Department of Biochemistry and Medical Biotechnologies, University Federico II of Naples and CEINGE Biotecnologie Avanzate, Via Gaetano Salvatore 486, Naples, Italy
    Eur J Clin Pharmacol 67:17-27. 2011
    ..It also gives an overview on the implication and importance of microRNA polymorphisms, transcriptomics, metabonomics, and proteomics in pharmacogenetics and pharmacogenomics studies...
  11. pmc Detection of erbB2 copy number variations in plasma of patients with esophageal carcinoma
    Immacolata Andolfo
    CEINGE, Centro di Ingegneria Genetica e Biotecnologia Avanzate, Naples, Italy
    BMC Cancer 11:126. 2011
    ..Here, we sought to isolate cell-free DNA released into the plasma of patients with esophageal carcinoma, to analyze copy number variations of marker genes in the search for early detection of tumor progression...
  12. doi Decreased concentration of adiponectin together with a selective reduction of its high molecular weight oligomers is involved in metabolic complications of myotonic dystrophy type 1
    Aurora Daniele
    CEINGE Biotecnologie Avanzate scarl, Via Gaetano Salvatore 486, Naples, Italy
    Eur J Endocrinol 165:969-75. 2011
    ..We analyzed circulating levels of adiponectin and its oligomers to determine whether their expression correlates with metabolic alterations in DM1 patients...
  13. pmc Proteomic analysis of sera from common variable immunodeficiency patients undergoing replacement intravenous immunoglobulin therapy
    Giuseppe Spadaro
    Dipartimento di Medicina Clinica, Scienze Cardiovascolari e Immunologiche e Centro Interdipartimentale di Ricerca in Immunologia di Base e Clinica, Universita degli Studi di Napoli Federico II, Via S Pansini 5, 80131 Napoli, Italy
    J Biomed Biotechnol 2011:706746. 2011
    ..The establishment of a cellular system, based on a human hepatocyte cell line HuH7, allowed to ascertain a potential role in the regulation of CLU gene expression by immunoglobulins...
  14. ncbi Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus-related chronic hepatitis: Insulin resistance and response to antiviral therapy
    Marcello Persico
    Internal Medicine and Hepatology Unit, Second University of Naples, Naples, Italy
    Hepatology 46:1009-15. 2007
    ..001), SOCS3 (P < 0.001), and MS (P < 0.001) were significantly related to the response to therapy. However, in a multivariate analysis, SOCS3 was the only independent predictor of the response (odds ratio = 6.7; P < 0.005)...