Roberto Berni Canani

Summary

Affiliation: Federico II University
Country: Italy

Publications

  1. doi request reprint Gastric acidity inhibitors and the risk of intestinal infections
    Roberto Berni Canani
    Department of Pediatrics, University of Naples, Naples, Italy
    Curr Opin Gastroenterol 26:31-5. 2010
  2. ncbi request reprint Growth hormone regulates intestinal ion transport through a modulation of the constitutive nitric oxide synthase-nitric oxide-cAMP pathway
    Roberto Berni Canani
    Department of Pediatrics, University Federico II, Via S Pansini, Naples 80131, Italy
    World J Gastroenterol 12:4710-5. 2006
  3. ncbi request reprint Saccharomyces boulardii: a summary of the evidence for gastroenterology clinical practice in adults and children
    R Berni Canani
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Naples, Italy
    Eur Rev Med Pharmacol Sci 15:809-22. 2011
  4. pmc Serum calprotectin: an antimicrobial peptide as a new marker for the diagnosis of sepsis in very low birth weight newborns
    Gianluca Terrin
    Department of Women Health and Territorial Medicine, University of Rome La Sapienza, 00185 Rome, Italy
    Clin Dev Immunol 2011:291085. 2011
  5. pmc Genotype-dependency of butyrate efficacy in children with congenital chloride diarrhea
    Roberto Berni Canani
    Department of Translational Medical Science Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples, Federico II Via S, Pansini, 5 80131 Naples, Italy
    Orphanet J Rare Dis 8:194. 2013
  6. doi request reprint Formula selection for management of children with cow's milk allergy influences the rate of acquisition of tolerance: a prospective multicenter study
    Roberto Berni Canani
    Department of Pediatrics, University of Naples, Federico II, Naples, Italy
    J Pediatr 163:771-7.e1. 2013
  7. pmc Calcium and vitamin D intakes in children: a randomized controlled trial
    Linda Cosenza
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    BMC Pediatr 13:86. 2013
  8. pmc Gut microbiota as potential therapeutic target for the treatment of cow's milk allergy
    Roberto Berni Canani
    Department of Translational Medicine, Pediatric Section, University of Naples Federico II, Naples 80131, Italy
    Nutrients 5:651-62. 2013
  9. pmc Tolerance to a new free amino acid-based formula in children with IgE or non-IgE-mediated cow's milk allergy: a randomized controlled clinical trial
    Roberto Berni Canani
    Department of Paediatrics, European Laboratory for the Investigation of Food Induced Diseases ELFID, University of Naples Federico II, Via S, Pansini, 5 80131, Naples, Italy
    BMC Pediatr 13:24. 2013
  10. doi request reprint Epigenetic mechanisms elicited by nutrition in early life
    Roberto Berni Canani
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Naples, Italy
    Nutr Res Rev 24:198-205. 2011

Collaborators

Detail Information

Publications50

  1. doi request reprint Gastric acidity inhibitors and the risk of intestinal infections
    Roberto Berni Canani
    Department of Pediatrics, University of Naples, Naples, Italy
    Curr Opin Gastroenterol 26:31-5. 2010
    ..We reviewed recent clinical studies performed in adults, children, and neonates exploring the possible association of gastric acidity inhibitors use with intestinal infections. Possible mechanisms have also been reported...
  2. ncbi request reprint Growth hormone regulates intestinal ion transport through a modulation of the constitutive nitric oxide synthase-nitric oxide-cAMP pathway
    Roberto Berni Canani
    Department of Pediatrics, University Federico II, Via S Pansini, Naples 80131, Italy
    World J Gastroenterol 12:4710-5. 2006
    ....
  3. ncbi request reprint Saccharomyces boulardii: a summary of the evidence for gastroenterology clinical practice in adults and children
    R Berni Canani
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Naples, Italy
    Eur Rev Med Pharmacol Sci 15:809-22. 2011
    ..Indications and dosage for several gastrointestinal diseases for a correct use of this probiotic are provided, and recent insights on its mechanisms of action and possible future clinical application are also discussed...
  4. pmc Serum calprotectin: an antimicrobial peptide as a new marker for the diagnosis of sepsis in very low birth weight newborns
    Gianluca Terrin
    Department of Women Health and Territorial Medicine, University of Rome La Sapienza, 00185 Rome, Italy
    Clin Dev Immunol 2011:291085. 2011
    ..In conclusion, serum calprotectin is an accurate marker of sepsis in very low birth weight newborns...
  5. pmc Genotype-dependency of butyrate efficacy in children with congenital chloride diarrhea
    Roberto Berni Canani
    Department of Translational Medical Science Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples, Federico II Via S, Pansini, 5 80131 Naples, Italy
    Orphanet J Rare Dis 8:194. 2013
    ..Currently available therapies are not able to limit the severity of diarrhea in CLD. Conflicting results have been reported on the therapeutic efficacy of oral butyrate...
  6. doi request reprint Formula selection for management of children with cow's milk allergy influences the rate of acquisition of tolerance: a prospective multicenter study
    Roberto Berni Canani
    Department of Pediatrics, University of Naples, Federico II, Naples, Italy
    J Pediatr 163:771-7.e1. 2013
    ..To prospectively evaluate the effect of different dietary management strategies on the rate of acquisition of tolerance in children with cow's milk allergy (CMA)...
  7. pmc Calcium and vitamin D intakes in children: a randomized controlled trial
    Linda Cosenza
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    BMC Pediatr 13:86. 2013
    ..Calcium (Ca(2+)) and vitamin D (VitD) play an important role in child health. We evaluated the daily intake of Ca(2+) and VitD in healthy children. Moreover, we demonstrate the efficacy of Ca(2+) and VitD supplementation...
  8. pmc Gut microbiota as potential therapeutic target for the treatment of cow's milk allergy
    Roberto Berni Canani
    Department of Translational Medicine, Pediatric Section, University of Naples Federico II, Naples 80131, Italy
    Nutrients 5:651-62. 2013
    ..The aim of this paper is to review what is currently known about the use of probiotics as dietary supplements in CMA...
  9. pmc Tolerance to a new free amino acid-based formula in children with IgE or non-IgE-mediated cow's milk allergy: a randomized controlled clinical trial
    Roberto Berni Canani
    Department of Paediatrics, European Laboratory for the Investigation of Food Induced Diseases ELFID, University of Naples Federico II, Via S, Pansini, 5 80131, Naples, Italy
    BMC Pediatr 13:24. 2013
    ..We prospectively assessed the tolerance to a new commercially available Aaf in children affected by IgE- or non-IgE-mediated CMA...
  10. doi request reprint Epigenetic mechanisms elicited by nutrition in early life
    Roberto Berni Canani
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Naples, Italy
    Nutr Res Rev 24:198-205. 2011
    ..More recently, the epigenetic mechanisms elicited by probiotics through the production of SCFA are hypothesised to be the key to understand how they mediate their numerous health-promoting effects from the gut to the peripheral tissues...
  11. pmc The epigenetic effects of butyrate: potential therapeutic implications for clinical practice
    Roberto Berni Canani
    Department of Pediatrics, University of Naples Federico II, Via S Pansini 5, Naples 80131, Italy
    Clin Epigenetics 4:4. 2012
    ..This review is focused on recent data regarding the epigenetic effects of butyrate with potential clinical implications in human medicine...
  12. ncbi request reprint The nutritional modulation of the evolving intestine
    Roberto Berni Canani
    Department of Pediatrics, University Federico II of Naples, Naples, Italy
    J Clin Gastroenterol 42:S197-200. 2008
    ..This paper is focused on the main components and mechanisms of action of the nutritional modulation on intestinal development...
  13. doi request reprint Mechanisms of action of zinc in acute diarrhea
    Roberto Berni Canani
    Department of Pediatrics, European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Italy
    Curr Opin Gastroenterol 27:8-12. 2011
    ..More recently, the mechanisms of action of zinc are becoming clearer. This review is focused on the new evidence on the mechanisms of action of zinc in acute diarrhea...
  14. doi request reprint Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes
    Roberto Berni Canani
    Department of Pediatrics, University of Naples Federico II, Via S Pansini, 5, 80131 Naples, Italy
    Eur J Pharmacol 626:266-70. 2010
    ..They also suggest that Zn(2+) interferes with three of the four main intracellular pathways of intestinal ion secretion that are involved in acute diarrhea...
  15. doi request reprint Recent progress in congenital diarrheal disorders
    Roberto Berni Canani
    Department of Pediatrics and European Laboratory for the Investigation on Food Induced Diseases, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy
    Curr Gastroenterol Rep 13:257-64. 2011
    ..The present review focuses on the recent advances made in understanding the pathophysiology of CDD that could potentially improve the clinical approach to these conditions...
  16. doi request reprint The optimal diagnostic workup for children with suspected food allergy
    Roberto Berni Canani
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Naples, Italy
    Nutrition 27:983-7. 2011
    ..An incorrect diagnosis is likely to result in unnecessary dietary restrictions, which, if prolonged, may adversely affect the child's nutritional status and growth...
  17. doi request reprint Ranitidine is associated with infections, necrotizing enterocolitis, and fatal outcome in newborns
    Gianluca Terrin
    Department of Women s Health and Territorial Medicine, University La Sapienza, Rome, Italy
    Pediatrics 129:e40-5. 2012
    ..The objective of this study was to investigate whether ranitidine treatment in very low birth weight (VLBW) infants is associated with an increased risk of infections, necrotizing enterocolitis (NEC), and fatal outcome...
  18. ncbi request reprint Effects of disease activity on anti-Saccharomyces cerevisiae antibodies: implications for diagnosis and follow-up of children with Crohn's disease
    Roberto Berni Canani
    Department of Pediatrics, University Federico II, Naples, Italy
    Inflamm Bowel Dis 10:234-9. 2004
    ....
  19. ncbi request reprint Faecal calprotectin as reliable non-invasive marker to assess the severity of mucosal inflammation in children with inflammatory bowel disease
    R Berni Canani
    Department of Paediatrics, University of Naples Federico II, Naples, Italy
    Dig Liver Dis 40:547-53. 2008
    ..An accurate monitoring of mucosal inflammation is important for an effective management of patients with inflammatory bowel disease. Intestinal inflammation can be detected by faecal calprotectin level determination...
  20. pmc Haemorrhagic gastritis in a neurologically impaired boy
    R Berni Canani
    Department of Paediatrics, University Federico II of Naples, Via S Pansini, 5 80131 Naples, Italy
    Gut 56:1511, 1535. 2007
  21. ncbi request reprint Diagnostic value of faecal calprotectin in paediatric gastroenterology clinical practice
    R Berni Canani
    Department of Pediatrics, University Federico II of Naples, Via S Pansini, 5, 80131 Naples, Italy
    Dig Liver Dis 36:467-70. 2004
    ..Faecal calprotectin (FC) is a new marker of intestinal inflammation. Data on FC in paediatric gastroenterology clinical practice are still scarce...
  22. ncbi request reprint Butyrate as an effective treatment of congenital chloride diarrhea
    Roberto Berni Canani
    Department of Pediatrics, University Federico II, Naples, Italy
    Gastroenterology 127:630-4. 2004
    ..In this case report, we report the therapeutic efficacy of butyrate on an 11-year-old patient affected by congenital chloride diarrhea...
  23. ncbi request reprint Combined use of noninvasive tests is useful in the initial diagnostic approach to a child with suspected inflammatory bowel disease
    Roberto Berni Canani
    Department of Pediatrics, University Federico II of Naples, Naples, Italy
    J Pediatr Gastroenterol Nutr 42:9-15. 2006
    ....
  24. ncbi request reprint Therapy with gastric acidity inhibitors increases the risk of acute gastroenteritis and community-acquired pneumonia in children
    Roberto Berni Canani
    Department of Pediatrics, University Federico II of Naples, Naples, Italy
    Pediatrics 117:e817-20. 2006
    ..To test the hypothesis that GA suppression could be associated with an increased risk of acute gastroenteritis and pneumonia in children treated with GA inhibitors, we conducted a multicenter, prospective study...
  25. ncbi request reprint Zinc inhibits cholera toxin-induced, but not Escherichia coli heat-stable enterotoxin-induced, ion secretion in human enterocytes
    Roberto Berni Canani
    Department of Pediatrics, University Federico II, Naples, Italy
    J Infect Dis 191:1072-7. 2005
    ..The objective of the present study was to investigate the effects of zinc on transepithelial ion transport under basal conditions and under conditions of enterotoxin-induced ion secretion...
  26. ncbi request reprint Nitric oxide produced by the enterocyte is involved in the cellular regulation of ion transport
    Roberto Berni Canani
    Department of Pediatrics, University Federico II, 5 80131 Naples, Italy
    Pediatr Res 54:64-8. 2003
    ....
  27. ncbi request reprint Guanylin and E. coli heat-stable enterotoxin induce chloride secretion through direct interaction with basolateral compartment of rat and human colonic cells
    Fabio Albano
    Department of Pediatrics, University Federico II, Via S Pansini 5, 80131 Naples, Italy
    Pediatr Res 58:159-63. 2005
    ..Guanylin shows the same pattern, suggesting that it plays a role in the regulation of ion transport in the colon, but the relative importance of serosally mediated secretion remains to be determined...
  28. ncbi request reprint Effects of a Lactobacillus paracasei B21060 based synbiotic on steatosis, insulin signaling and toll-like receptor expression in rats fed a high-fat diet
    Giuseppina Mattace Raso
    Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy
    J Nutr Biochem 25:81-90. 2014
    ..Overall, our data indicate that the L. paracasei B21060 based synbiotic is effective in reducing the severity of liver injury and IR associated with high fat intake, suggesting its possible therapeutic/preventive clinical utilization. ..
  29. ncbi request reprint Rotavirus induces a biphasic enterotoxic and cytotoxic response in human-derived intestinal enterocytes, which is inhibited by human immunoglobulins
    Giulio De Marco
    Department of Pediatrics, University Federico II of Naples, Naples, Italy
    J Infect Dis 200:813-9. 2009
    ..The combined enterotoxic and cytotoxic effects may be responsible for the increased severity of diarrhea due to rotavirus infection, and both are counteracted by human serum immunoglobulin...
  30. ncbi request reprint Zinc fights diarrhoea in HIV-1-infected children: in-vitro evidence to link clinical data and pathophysiological mechanism
    Roberto Berni Canani
    Department of Pediatrics, University Federico II, Naples, Italy
    AIDS 21:108-10. 2007
    ..Our data support a 'zinc approach' in adjunct to specific antiretroviral therapy in HIV-1-infected children...
  31. ncbi request reprint Effects of HIV-1 Tat protein on ion secretion and on cell proliferation in human intestinal epithelial cells
    Roberto Berni Canani
    Department of Pediatrics, University of Naples Federico II, Italy
    Gastroenterology 124:368-76. 2003
    ..The HIV-1 transactivating factor protein (Tat) is a key factor in the pathogenesis of acquired immunodeficiency syndrome. We investigated whether Tat could directly induce ion secretion and cell damage in enterocytes...
  32. ncbi request reprint Inhibitory effect of HIV-1 Tat protein on the sodium-D-glucose symporter of human intestinal epithelial cells
    Roberto Berni Canani
    Department of Pediatrics, University Federico II of Naples, Italy
    AIDS 20:5-10. 2006
    ..Because sugar malabsorption is a frequent feature in AIDS patients, we evaluated whether Tat inhibits intestinal glucose absorption...
  33. pmc Probiotics for treatment of acute diarrhoea in children: randomised clinical trial of five different preparations
    Roberto Berni Canani
    Department of Paediatrics, University of Naples Federico II, Naples, Italy
    BMJ 335:340. 2007
    ..To compare the efficacy of five probiotic preparations recommended to parents in the treatment of acute diarrhoea in children. Design Randomised controlled clinical trial in collaboration with family paediatricians over 12 months...
  34. doi request reprint Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms
    Anna Iacono
    Department of Experimental Pharmacology, University of Naples Federico II, 80131 Naples, Italy
    J Nutr Biochem 22:699-711. 2011
    ....
  35. doi request reprint Efficacy of a new hypotonic oral rehydration solution containing zinc and prebiotics in the treatment of childhood acute diarrhea: a randomized controlled trial
    Annalisa Passariello
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    J Pediatr 158:288-92.e1. 2011
    ..To evaluate the efficacy of a hypotonic oral rehydration solution (ORS) containing zinc and prebiotics for treatment of acute diarrhea in children...
  36. pmc Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet
    Giuseppina Mattace Raso
    Department of Pharmacy, University of Naples Federico II, Naples, Italy
    PLoS ONE 8:e68626. 2013
    ..We evaluated the effects of sodium butyrate (butyrate) and its synthetic derivative N-(1-carbamoyl-2-phenyl-ethyl) butyramide (FBA) in a rat model of insulin resistance and steatosis induced by high-fat diet (HFD)...
  37. ncbi request reprint Congenital diarrheal disorders: improved understanding of gene defects is leading to advances in intestinal physiology and clinical management
    Roberto Berni Canani
    Department of Pediatrics, Italy
    J Pediatr Gastroenterol Nutr 50:360-6. 2010
    ..Furthermore, carrier and prenatal molecular diagnosis may help pediatricians better manage the condition in the early stages of life...
  38. ncbi request reprint Microflora in inflammatory bowel diseases: a pediatric perspective
    Eugenia Bruzzese
    Department of Pediatrics, University Federico II, Naples, Italy
    J Clin Gastroenterol 38:S91-3. 2004
    ..This approach may be a key for understanding the pathophysiology of intestinal inflammation and may disclose novel strategies to educate better the immune system, particularly during its developmental stage...
  39. pmc Diarrhea in neonatal intensive care unit
    Annalisa Passariello
    Department of Pediatrics, University of Naples Federico II, Naples, 80131, Italy
    World J Gastroenterol 16:2664-8. 2010
    ..To investigate the frequency, etiology, and current management strategies for diarrhea in newborn...
  40. doi request reprint Minimal enteral feeding reduces the risk of sepsis in feed-intolerant very low birth weight newborns
    Gianluca Terrin
    Department of Paediatrics, University of Naples Federico II, Naples, Italy
    Acta Paediatr 98:31-5. 2009
    ..To evaluate the efficacy and safety of minimal enteral feeding (MEF) nutritional practice in feed-intolerant very low birth weight (VLBW) infants...
  41. doi request reprint Crenotherapy modulates the expression of proinflammatory cytokines and immunoregulatory peptides in nasal secretions of children with chronic rhinosinusitis
    Annalisa Passariello
    Department of Pediatrics, University of Naples Federico II, Via S Pansini 5, Naples, Italy
    Am J Rhinol Allergy 26:e15-9. 2012
    ..The aim of this study was to investigate the effects of crenotherapy with sulfate-sodium-chloride water on mucosal markers of inflammation in children with CRS...
  42. pmc Potential beneficial effects of butyrate in intestinal and extraintestinal diseases
    Roberto Berni Canani
    Roberto Berni Canani, Margherita Di Costanzo, Ludovica Leone, Monica Pedata, Department of Pediatrics, University of Naples Federico II, Via S Pansini 5, Naples 80131, Italy
    World J Gastroenterol 17:1519-28. 2011
    ..These data suggest a wide spectrum of positive effects exerted by butyrate, with a high potential for a therapeutic use in human medicine...
  43. ncbi request reprint The diagnosis of food allergy in children
    Roberto Berni Canani
    Department of Paediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Curr Opin Pediatr 20:584-9. 2008
    ..To give an update about the optimal diagnostic work-up for children with suspected food allergy...
  44. ncbi request reprint Adherence to antiretroviral therapy in HIV-infected children in Italy
    F Albano
    Department of Pediatrics, University Federico II, Naples, Italy
    AIDS Care 11:711-4. 1999
    ....
  45. doi request reprint Comparative therapeutic effects of metformin and vitamin E in a model of non-alcoholic steatohepatitis in the young rat
    Giuseppina Mattace Raso
    Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
    Eur J Pharmacol 604:125-31. 2009
    ..Moreover a decrease of PPAR-gamma expression was also shown. These findings confirm the efficacy of both drugs as therapeutic tools in preventing the early onset of liver damage and non-alcoholic fatty liver disease progression...
  46. doi request reprint Peripheral blood immune response elicited by beta-lactoglobulin in childhood cow's milk allergy
    Immacolata Vocca
    Institute of Food Sciences, CNR, Avellino 83100, Italy
    Pediatr Res 70:549-54. 2011
    ..This study highlights the use of shortly stimulated peripheral blood cells to investigate the food-induced immune responses...
  47. doi request reprint Probiotics as prevention and treatment for diarrhea
    Alfredo Guarino
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    Curr Opin Gastroenterol 25:18-23. 2009
    ..To critically appraise evidence on probiotic use for prevention and treatment of diarrhea in children and adults...
  48. pmc Acute disseminated encephalomyelitis presenting as fever of unknown origin: case report
    Margherita Di Costanzo
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    BMC Pediatr 11:103. 2011
    ..The highest incidence of ADEM is observed during childhood and it usually occurs following a viral or bacterial infection or, more rarely, following a vaccination, or without a preceding cause...
  49. ncbi request reprint Effects of nutritional rehabilitation on intestinal function and on CD4 cell number in children with HIV
    Alfredo Guarino
    Department of Pediatrics, University Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 34:366-71. 2002
    ..The authors tested the hypothesis that nutritional support improves intestinal and immune functions in children infected with human immunodeficiency virus (HIV)...
  50. ncbi request reprint Costs associated with outpatient diarrhoea in infants and toddlers: a nationwide study of the Italian Society of Paediatric Gastroenterology and Hepatology (SIGEP)
    M Fontana
    Department of Paediatrics, Children s Hospital V Buzzi, Via Castelvetro 32, 20154 Milan, Italy
    Dig Liver Dis 36:523-7. 2004
    ..As diarrhoea mortality is negligible in Italy, other costs should be considered when planning health strategies. Little is known about the costs associated with diarrhoea in Italian children...