Research Topics
| Bernadette BiondiSummaryAffiliation: Federico II University Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Subclinical hyperthyroidism: clinical features and treatment optionsBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, 80131 Naples, Italy
Eur J Endocrinol 152:1-9. 2005..Subclinical hyperthyroidism and its related clinical manifestations are reversible and may be prevented by timely treatment...- Thyroid-hormone therapy and thyroid cancer: a reassessmentBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Naples, Italy
Nat Clin Pract Endocrinol Metab 1:32-40. 2005..5 mU/l). Only selected patients with high-risk papillary and follicular thyroid cancer require long-term TSH-suppressive doses of L-T(4). In these patients, careful monitoring is necessary to avoid undesirable effects on bone and heart... 
Mechanisms in endocrinology: Heart failure and thyroid dysfunctionBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Italy
Eur J Endocrinol 167:609-18. 2012..The aim of this review article was to assess the results of the prospective studies that evaluated the risk of HF in patients with overt and subclinical thyroid disease and discuss the mechanism of this dysfunction...- How could we improve the increased cardiovascular mortality in patients with overt and subclinical hyperthyroidism?Bernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
Eur J Endocrinol 167:295-9. 2012..Randomized controlled clinical trials are needed to assess the benefits of treatment to improve the cardiovascular mortality and morbidity of mild and overt hyperthyroidism... - Natural history, diagnosis and management of subclinical thyroid dysfunctionBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
Best Pract Res Clin Endocrinol Metab 26:431-46. 2012..Mild SHypo should be treated in infertile and pregnant women... - Combination treatment with T4 and T3: toward personalized replacement therapy in hypothyroidism?Bernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
J Clin Endocrinol Metab 97:2256-71. 2012..The aim of this review is to assess the physiological basis and the results of current studies on this topic... - The clinical significance of subclinical thyroid dysfunctionBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
Endocr Rev 29:76-131. 2008..Lastly, we address the issue of the need to treat slight thyroid hormone deficiency or excess in relation to the patient's age... - Endothelial-mediated coronary flow reserve in patients with mild thyroid hormone deficiencyBernadette Biondi
Department of Clinical and Molecular Endocrinology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
Eur J Endocrinol 161:323-9. 2009..Although coronary flow reserve (CFR) is reduced in patients with subclinical hypothyroidism (SHypo), the endothelial response of coronary vasomotion has never been explored in this clinical setting... - Cardiovascular effects of mild hypothyroidismBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Naples, Italy
Thyroid 17:625-30. 2007.... - Benefits of thyrotropin suppression versus the risks of adverse effects in differentiated thyroid cancerBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Naples, Italy
Thyroid 20:135-46. 2010.... - Effects of subclinical thyroid dysfunction on the heartBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II School of Medicine, 80131 Naples, Italy
Ann Intern Med 137:904-14. 2002..Mounting evidence indicates that subclinical thyroid dysfunction has important clinical effects and prognostic implications, supporting the view that it is not a compensated biochemical change sensu strictu... - Effects of thyroid hormone on the cardiovascular systemSerafino Fazio
Department of Clinical Medicine and Cardiovascular Sciences, University of Naples Federico II School of Medicine, 80131, Naples, Italy
Recent Prog Horm Res 59:31-50. 2004.... - Cardiovascular safety of acute recombinant human thyrotropin administration to patients monitored for differentiated thyroid cancerBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II School of Medicine, 80131 Naples, Italy
J Clin Endocrinol Metab 88:211-4. 2003..Our data demonstrate that rhTSH does not alter cardiovascular function acutely. Consequently, it can safely be used in the routine staging of patients affected by differentiated thyroid cancer... - Subclinical hypothyroidism and cardiac functionBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II School of Medicine, Naples, Italy
Thyroid 12:505-10. 2002..Therefore, it would seem appropriate to initiate timely treatment of patients with mild thyroid failure to prevent cardiac involvement... - Subclinical hypothyroidism and cardiovascular risk: a reason to treat?Emiliano A Palmieri
Department of Clinical Medicine, Cardiovascular and Immunological Science, University Federico II School of Medicine, Naples, Italy
Treat Endocrinol 3:233-44. 2004.... - Impact of resistance to thyroid hormone on the cardiovascular system in adultsMelania Pulcrano
Department of Clinical and Molecular Endocrinology and Oncology, University Federico II of Naples, Via S Pansini 5, Naples, Italy
J Clin Endocrinol Metab 94:2812-6. 2009..The clinical manifestations of resistance to thyroid hormone (RTH) are highly variable, and the impact of RTH on the cardiovascular system has been poorly investigated... - Flow cytometry phenotypization of thyroidal lymphoid infiltrate and functional status in Hashimoto's thyroiditisPio Zeppa
Department of Anatomic Pathology and Cytopathology, Faculty of Medicine and Surgery, Universita di Napoli Federico II, Naples, Italy
Anal Quant Cytol Histol 28:148-56. 2006..To evaluate the thyroidal lymphoid infiltrate (TLI) in thyroidal functional status (TFS) for differences among patients with Hashimoto's thyroiditis (HT)... - Effects of thyroid hormone on cardiac function: the relative importance of heart rate, loading conditions, and myocardial contractility in the regulation of cardiac performance in human hyperthyroidismBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University Federico II School of Medicine, 80131 Naples, Italy
J Clin Endocrinol Metab 87:968-74. 2002 - Patients with subclinical Cushing's syndrome due to adrenal adenoma have increased cardiovascular riskLibuse Tauchmanova
Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, Via S Pansini n 5, 801 31 Naples, Italy
J Clin Endocrinol Metab 87:4872-8. 2002..This finding supports the concept that chronic mild endogenous cortisol excess may have important systemic effects on the human body... - Cardiovascular involvement in patients with different causes of hyperthyroidismBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
Nat Rev Endocrinol 6:431-43. 2010..Consequently, the etiology of hyperthyroidism must be established to enable correct treatment of the disease and the cardiovascular complications... 
Adjuvant treatment with thyrotropin alpha for remnant ablation in thyroid cancerBernadette Biondi
Department of Clinical and Molecular, Endocrinology and Oncology, University of Naples Federico II, Naples, Italy
Biologics 3:9-13. 2009..More studies are required to establish the amount of radioiodine to be administered especially in high-risk patients...- Recombinant human TSH modulates in vivo C-telopeptides of type-1 collagen and bone alkaline phosphatase, but not osteoprotegerin production in postmenopausal women monitored for differentiated thyroid carcinomaGherardo Mazziotti
Department of Clinical and Experimental Medicine, F. Magrassi and A. Lanzara, Second University of Naples, Naples, Italy
J Bone Miner Res 20:480-6. 2005..The activity of TSH occurs specifically in postmenopausal women in whom the negative effects of L-T4 suppressive therapy on bone mass and metabolism are more marked compared with premenopausal women... - Enhancement of vascular endothelial function by recombinant human thyrotropinRaffaele Napoli
Department of Internal Medicine and Cardiovascular Sciences, University Federico II, Via Pansini 5, Naples, Italy
J Clin Endocrinol Metab 93:1959-63. 2008..The possibility that TSH also affects the cardiovascular system has been poorly explored. Endothelial cells and vascular smooth muscle cells possess TSH receptors... - Hypothyroidism as a risk factor for cardiovascular diseaseBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II School of Medicine, Via S. Pansini 5, 80131, Naples, Italy
Endocrine 24:1-13. 2004..This constellation of reversible cardiovascular abnormalities in patient with TSH levels <10 mU/L indicate that the benefits of treatment of mild thyroid failure with appropriate doses of L-thyroxine outweigh the risk... - Invited commentary: Cardiovascular mortality in subclinical hyperthyroidism: an ongoing dilemmaBernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
Eur J Endocrinol 162:587-9. 2010.... - Should we treat all subjects with subclinical thyroid disease the same way?Bernadette Biondi
Department of Clinical and Molecular Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
Eur J Endocrinol 159:343-5. 2008 - Gender differences in the prevalence, clinical features and response to cabergoline in hyperprolactinemiaAnnamaria Colao
Department of Molecular and Clinical Endocrinology, Federico II University of Naples, Via S Pansini 5, Italy
Eur J Endocrinol 148:325-31. 2003..Whether this reflects only a delay in diagnosis in men or a true gender difference in tumor pathogenesis is still unclear... - The importance of using strict inclusion criteria in subclinical hypothyroid studiesBernadette Biondi
Am J Med 114:76; author reply 77. 2003 - Recombinant human thyrotropin reduces serum vascular endothelial growth factor levels in patients monitored for thyroid carcinoma even in the absence of thyroid tissueFrancesca Sorvillo
Department of Clinical and Experimental Medicine F. Magrassi and A. Lanzara, Second University of Naples, Italy
J Clin Endocrinol Metab 88:4818-22. 2003..This result would suggest that TSH may be able in vivo to regulate VEGF production from tissues other than the thyroid gland... - Screening and treatment for subclinical thyroid diseaseBernadette Biondi
JAMA 291:1562; author reply 1562-3. 2004 - Short-term hypothyroidism after Levothyroxine-withdrawal in patients with differentiated thyroid cancer: clinical and quality of life consequencesLeonidas H Duntas
Endocrine Unit, Evgenidion Hospital, University of Athens, 20 Papadiamantopoulou St, 11528 Athens, Greece
Eur J Endocrinol 156:13-9. 2007.... - Thyroid B-flow twinkling sign: a new feature of papillary cancerLuca Brunese
Department of Health Science, Chair of Radiology, University of Molise, Campobasso, Italy
Eur J Endocrinol 159:447-51. 2008..Using B-flow imaging (BFI), we identified a new sign (the twinkling sign; BFI-TS) in 'suspect' PTC nodules, which appeared to be generated by microcalcifications...