Research Topics
Genomes and Genes | M BifulcoSummaryAffiliation: Federico II University Country: Italy Publications
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Publications
Targeting the endocannabinoid system in cancer therapy: a call for further researchMaurizio Bifulco
Dipartimento di Scienze Farmaceutiche, , Fisciano, Salerno, Italy
Nat Med 8:547-50. 2002
2',3'-Cyclic nucleotide 3'-phosphodiesterase: a membrane-bound, microtubule-associated protein and membrane anchor for tubulinMaurizio Bifulco
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, 84084 Fisciano, Salerno, Italy
Proc Natl Acad Sci U S A 99:1807-12. 2002....- Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growthM Bifulco
Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
FASEB J 15:2745-7. 2001.... - A new strategy to block tumor growth by inhibiting endocannabinoid inactivationMaurizio Bifulco
Istituto di Endocrinologia ed Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, and Dipartimento di Biologia e Patologia Cellulare e Molecolare L Califano, Universita di Napoli Federico II, Italy
FASEB J 18:1606-8. 2004.... - [The endocannabinoid system as a target for the development of new drugs for cancer therapy]Maurizio Bifulco
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita Federico II, Napoli
Recenti Prog Med 94:194-8. 2003..This evidence is reviewed here and suggests that future anti-cancer therapy might be developed from our knowledge of how the endocannabinoid system controls the growth and metastasis of malignant cells... - Role of the isoprenoid pathway in ras transforming activity, cytoskeleton organization, cell proliferation and apoptosisMaurizio Bifulco
Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, via Ponte Don Melillo 84084, Fisciano, Salerno, Italy
Life Sci 77:1740-9. 2005.... - Cannabinoids and cancer: pros and cons of an antitumour strategyMaurizio Bifulco
Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, Fisciano 84084, Salerno, Italy
Br J Pharmacol 148:123-35. 2006..In this article, we will review the principal molecular pathways modulated by cannabinoids on cancer and summarize pros and cons evidence on the possible future use of endocannabinoid-based drugs in cancer therapy... - Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (review)Maurizio Bifulco
Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, 84084 Fisciano SA, Italy
Oncol Rep 17:813-6. 2007.... - Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cellsV Di Marzo
Istituto per la Chimica di Molecole di Interesse Biologico, Via Toiano 6, 80072, Arco Felice, Napoli, Italy
Biochem J 358:249-55. 2001..We suggest that long-term PEA treatment of cells may positively affect the pharmacological activity of AEA, in part by inhibiting FAAH expression... - Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferationD Melck
Istituto per la Chimica di Molecole di Interesse Biologico, Consiglio Nazionale delle Ricerche, Arco Felice Na, Italy
Endocrinology 141:118-26. 2000..These findings suggest that endogenous cannabinoids and CB1 receptor agonists are potential negative effectors of PRL- and NGF-induced biological responses, at least in some cancer cells... - The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferationL De Petrocellis
Istituto di Cibernetica, Consiglio Nazionale delle Ricerche, Consiglio Nazionale delle Ricerche, Via Toiano 6, 80072 Arco Felice, Naples, Italy
Proc Natl Acad Sci U S A 95:8375-80. 1998..These data suggest that anandamide blocks human breast cancer cell proliferation through CB1-like receptor-mediated inhibition of endogenous prolactin action at the level of prolactin receptor... - Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptorsD Melck
Istituto per la Chimica di Molecole di Interesse Biologico, , 80131, Napoli, Italy
Biochem Biophys Res Commun 262:275-84. 1999..e., the inhibition of human breast cancer cell (HBCC) proliferation, arvanil was shown to behave as a "hybrid" activator of cannabinoid and vanilloid receptors... - Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasisGiuseppe Portella
Endocannabinoid Research Group, Istituto di Endocrinologia ed Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, and Dipartimento di Biologia e Patologia Cellulare e Molecolare L. Califano, , Italy
FASEB J 17:1771-3. 2003..Our findings indicate that CB1 receptor agonists might be used therapeutically to retard tumor growth in vivo by inhibiting at once tumor growth, angiogenesis, and metastasis... - Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Down-regulation by v-K-ras oncogeneB Perillo
Dipartimento di Biologia e Patologia Cellulare e Molecolare L Califano, Universita Federico II, Napoli, Italy
J Biol Chem 270:15237-41. 1995..This is the first demonstration that active v-K-ras down-regulates HMG-CoA reductase expression... - Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expressionM Vitale
Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita Federico II, Via S Pansini 5, 80131, Naples, Italy
FEBS Lett 462:57-60. 1999..The phosphatase inhibitor sodium orthovanadate opposed anoikis when added to the cells within 6 h, suggesting a role for phosphorylated proteins... - Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cellsA M Malfitano
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Fisciano SA, Italy
Br J Pharmacol 153:1003-10. 2008..In this study we have investigated the anti-proliferative and immunomodulatory effects of SR141716 in human peripheral blood mononuclear cells (PBMCs)... - Anandamide inhibits adhesion and migration of breast cancer cellsClaudia Grimaldi
Dipartimento di Scienze Farmaceutiche, Endocannabinoid Research Group, , Fisciano SA, Italy
Exp Cell Res 312:363-73. 2006.... - Dietary and hypothyroid hypercholesterolemia induces hepatic apolipoprotein E expression in the rat: direct role of cholesterolM Santillo
Dipartimento di Neuroscienze e della Comunicazione Interumana Sezione di Fisiologia, Universita di Napoli Federico II, Napoli, Italy
FEBS Lett 463:83-6. 1999..Our data demonstrate that hypercholesterolemia, apart of the cause (diet or hypothyroidism) induces liver apo E expression in the rat and that this effect can be directly related, via cAMP, to cholesterol... 
The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathwayChiara Laezza
Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, Napoli, Italy
Endocr Relat Cancer 15:965-74. 2008..We suggest that the inhibitory effect of Met-F-AEA on tumor cell migration could be related to RHOA-ROCK-dependent signaling pathway...- Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacySimona Pisanti
Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Salerno, Italy
J Cell Physiol 211:495-503. 2007..Thus, our results suggest that anandamide could be involved in the control of cancer growth targeting both tumor cell proliferation and the angiogenic stimulation of the vasculature... - Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colonAntonietta Santoro
Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Italy
Int J Cancer 125:996-1003. 2009..Our findings suggest that rimonabant is able to inhibit colorectal cancer cell growth at different stages of colon cancer pathogenesis inducing mitotic catastrophe in vitro... - Inhibitors of Ras farnesylation revert the increased resistance to oxidative stress in K-Ras transformed NIH 3T3 cellsM Santillo
Dipartimento di Neuroscienze, Sezione Fisiologia, Universita degli Studi di Napoli Federico II, Napoli, Italy
Biochem Biophys Res Commun 229:739-45. 1996..These results suggest that farnesylation inhibitors could be used as an adjuvant therapy to improve the tumoricidal effect of cancer treatment based upon free-radical production in ras-dependent tumors... - Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systemsLuciano De Petrocellis
Istituto di Cibernetica Eduardo Caianiello, Consiglio Nazionale delle Ricerche, Comprensorio Olivetti, Pozzuoli, Napoli, Italy
Fundam Clin Pharmacol 16:297-302. 2002..These 'entourage' effects of PEA might be attributable to modulation of VR1 activity, and could underlie the enhancement by PEA, described here for the first time, of the antiproliferative effects of VR1 receptor agonists... - Presence of CuZn superoxide dismutase in human serum lipoproteinsP Mondola
Dipartimento di Neuroscienze e della Comunicazione Interumana Sez Fisiologia, Via S Pansini 5, 80131, Naples, Italy
FEBS Lett 467:57-60. 2000..The CuZn-SOD bound to LDL and HDL could exert a physiological protective role against oxidative damage of these lipoprotein classes that carry out a crucial role in the cholesterol transport... - Effect of Cu,Zn superoxide dismutase on cholesterol metabolism in human hepatocarcinoma (HepG2) cellsPaolo Mondola
Dipartimento di Neuroscienze e Scienze del Comportamento, Sezione di Fisiologia, Universita Degli Studi Di Napoli, Federico II, Via S Pansini, 5, 80131 Naples, Italy
Biochem Biophys Res Commun 295:603-9. 2002.... - Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitisAnna Maria Malfitano
Dipartimento di Scienze Farmaceutiche, Universita' di Salerno, Via Ponte don Melillo 84084 Fisciano (Salerno, Italy
J Neuroimmunol 171:110-9. 2006..Our findings have relevance for the use of arvanil and related compounds as a novel immunotherapeutic approach in the treatment of multiple sclerosis... - Lovastatin-induced apoptosis in thyroid cells: involvement of cytochrome c and lamin BT Di Matola
Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita Federico II, Via S Pansini 5, 80131, Naples, Italy
Eur J Endocrinol 145:645-50. 2001..CONCLUSIONS: These data demonstrate that, in TAD-2 thyroid cells, lovastatin induces lamin B proteolysis and inhibits its nuclear localization and induces cytochrome c release from mitochondria into the cytosol... - Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cellsDaniela Sarnataro
Dip di Scienze Farmaceutiche, Universita degli Studi di Salerno, Italy
FEBS Lett 579:6343-9. 2005..Indeed MCD completely blocked the clustering of CB1R at the plasma membrane. On the contrary the lysosomal localization of CB1R was impaired by this treatment only after AEA binding... - The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits human breast cancer cell proliferation through a lipid raft-mediated mechanismDaniela Sarnataro
Dipartimento di Scienze Farmaceutiche, , Via Ponte Don Melillo, 84084 Fisciano (Salerno, Italy
Mol Pharmacol 70:1298-306. 2006..Taken together, our results suggest that SR141716 inhibits human breast cancer cell growth via a CB1R lipid raft/caveolae-mediated mechanism... - HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathwayChiara Laezza
Dipartimento di Scienze Farmaceutiche, , Via Ponte Don Melillo, 84084, Fisciano, Salerno, Italy
J Mol Med 84:967-73. 2006..Our data suggest that lovastatin is an efficient inhibitor of goitrogenesis and provide a rationale for innovative therapeutic strategies employing statins in the treatment of nodular goiter in humans... - Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatinPatrizia Gazzerro
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Fisciano Salerno, Italy
Oncol Rep 23:171-5. 2010..Our findings suggest that the combined synergic effect of SR141716 and oxaliplatin improves the blocking of colon cancer cell proliferation. Therefore, this combination merits further explorations in preclinical and clinical settings... - Protection of human endothelial cells from oxidative stress: role of Ras-ERK1/2 signalingGiovanni Cuda
Dipartimento di Medicina Sperimentale e Clinica G. Salvatore, , Napoli, Italy
Circulation 105:968-74. 2002.... - Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cellsSilvana Libertini
Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita di Napoli Federico II, Via S Pansini 5, 80131, Napoli, Italy
Endocrinology 148:5186-94. 2007..Lovastatin treatment could be exploited to increase the efficacy of oncolytic adenoviruses, and further studies are warranted to confirm the feasibility of the approach in ATC patients... - Metabolically labile cannabinoid esters: a 'soft drug' approach for the development of cannabinoid-based therapeutic drugsF Minutolo
Dipartimento di Scienze Farmaceutiche, Universita di Pisa, Via Bonanno 6, 56126, Pisa, Italy
Bioorg Med Chem Lett 17:4878-81. 2007..This may constitute a possible solution to the psychotropic side effects encountered when cannabinoids are therapeutically employed as local analgesic or antiglaucoma agents... - Biological and pharmacological roles of N6-isopentenyladenosine: an emerging anticancer drugMaurizio Bifulco
Dipartmento di Scienze Farmaceutiche, Universita di Salerno, 84084 Fisciano, SA, Italy
Anticancer Agents Med Chem 8:200-4. 2008..In addition, preliminary clinical observation seems to indicate a possible use of N6-Isopentenyladenosine as anticancer drug... - Rimonabant-induced apoptosis in leukemia cell lines: activation of caspase-dependent and -independent pathwaysDario Gallotta
Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano SA, Italy
Biochem Pharmacol 80:370-80. 2010..Moreover, SR141716 negatively modulated, especially in U937, the PI3K/AKT pathways. In conclusion, our data indicate that SR141716 elicits alternative response and/or cell death pathways depending on the cell type affected... - N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1Chiara Laezza
Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, Naples, Italy
Int J Cancer 124:1322-9. 2009..Overall, our data show that JNK, could play an important role in i6A-mediated apoptosis in DLD1 human colon cancer cells... - Cannabinoid receptor CB1 antagonists state of the art and challengesMaurizio Bifulco
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Fisciano, Salerno, Italy
Vitam Horm 81:159-89. 2009.... - Rimonabant: just an antiobesity drug? Current evidence on its pleiotropic effectsMaurizio Bifulco
Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Salerno, Italy
Mol Pharmacol 71:1445-56. 2007..Here we review recent data from the literature and discuss the full pharmacological potential of this drug... - Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cellsChiara Laezza
IEOS CNR, Napoli, Italy
FEBS Lett 580:6076-82. 2006..The observed mechanism of action, already reported for well-known chemotherapeutic drugs, provides strong evidence for a direct role of anandamide related compounds in the activation of cell cycle checkpoints... - The endocannabinoid system and its therapeutic exploitationVincenzo Di Marzo
Endocannabinoid Research Group, Institute of Biomolecular Chemistry, National Research Council, Via Campi Flegrei 34, Comprensorio Olivetti, 80078 Pozzuoli, Napoli, Italy
Nat Rev Drug Discov 3:771-84. 2004..We explore the conditions under which the potential of targeting the endocannabinoid system might be realized in the years to come... - Involvement of Akt/NF-κB pathway in N6-isopentenyladenosine-induced apoptosis in human breast cancer cellsChiara Laezza
Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, Naples, Italy
Mol Carcinog 49:892-901. 2010..The results of this study indicate that i6A decreases cell proliferation and induces apoptotic cell death in human breast cancer cells, possibly by decreasing signal transduction through the Akt/NF-κB cell survival pathway... - The cannabinoid CB1 receptor antagonist rimonabant stimulates 2-deoxyglucose uptake in skeletal muscle cells by regulating the expression of phosphatidylinositol-3-kinaseIolanda Esposito
Dipartimento di Biologia e Patologia Cellulare e Molecolare and Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche, Universita degli Studi di Napoli Federico II, Napoli, Italy
Mol Pharmacol 74:1678-86. 2008..Thus, modulation of CB1 regulates glucose uptake at the level of the PI3K signaling system in skeletal muscle cells. Interfering with CB1 signaling may therefore ameliorate glucoregulatory functions in peripheral tissues... - Therapeutic potential of statins in thyroid proliferative diseaseMaurizio Bifulco
Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano (Salerno, Italy
Nat Clin Pract Endocrinol Metab 4:242-3. 2008 - Effect of unsaturated fat intake from Mediterranean diet on rat liver mRNA expression profile: selective modulation of genes involved in lipid metabolismDavide Eletto
Dipartimento di Scienze Farmaceutiche, , Via Ponte Don Melillo, I-84084 Fisciano (SA, Italy
Nutr Metab Cardiovasc Dis 15:13-23. 2005..Some of these genes are also reported to be similarly modulated by the action of fibrates, but without the complete gene activation typical of these PPARalpha ligands... - Endocannabinoids in endocrine and related tumoursMaurizio Bifulco
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, 84084 Fisciano Salerno, Italy IEOS, CNR Napoli, 80131 Napoli, Italy
Endocr Relat Cancer 15:391-408. 2008.... - Verminoside- and verbascoside-induced genotoxicity on human lymphocytes: involvement of PARP-1 and p53 proteinsAntonietta Santoro
Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
Toxicol Lett 178:71-6. 2008.... - From cannabis to endocannabinoids in multiple sclerosis: a paradigm of central nervous system autoimmune diseasesAnna Maria Malfitano
Dipartimento di Scienze Farmaceutiche, Universita' di Salerno, Fisciano (SA, Italy
Curr Drug Targets CNS Neurol Disord 4:667-75. 2005.... - The N-terminal domain of 2',3'-cyclic nucleotide 3'-phosphodiesterase harbors a GTP/ATP binding siteStefania Stingo
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, Fisciano SA 84084, Italy
Chem Biol Drug Des 70:502-10. 2007..Therefore, our findings suggest new functional and structural property of the N-terminal domain of CNPase... - Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cellsAnna Maria Malfitano
Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Fisciano SA, Italy
Immunol Lett 109:145-54. 2007..We showed a transcriptional control of the CD36 gene by arvanil and anandamide associated with an increased protein expression, thus suggesting a possible role of CD36 in anandamide and arvanil anti-inflammatory pattern... - Structures and micelle locations of the nonlipidated and lipidated C-terminal membrane anchor of 2',3'-cyclic nucleotide-3'-phosphodiesteraseCinzia Esposito
Department of Pharmaceutical Sciences, University of Salerno, I 84084 Fisciano, Italy
Biochemistry 47:308-19. 2008..A general model is proposed in which the post-translational lipidation is an important biomolecular trick to enlarge the hydrophobic surface and to enable the contact of the protein with membrane... - Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptorsJason W Brooks
Pain Research Group, Department of Anaesthetics, Faculty of Medicine, Imperial College, Chelsea and Westminster Hospital Campus, London, UK
Eur J Pharmacol 439:83-92. 2002..These findings suggest that activation by arvanil of sites of action different from cannabinoid CB(1)/CB(2) receptors and vanilloid VR1 receptors leads to anti-spastic/analgesic effects that might be exploited therapeutically... - Possible endocannabinoid control of colorectal cancer growthAlessia Ligresti
Endovannabinoid Research Group, Institute of Biomolecular Chemistry, Pozzuoli, Italy
Gastroenterology 125:677-87. 2003..CONCLUSIONS: Endocannabinoid levels are enhanced in transformed colon mucosa cells possibly to counteract proliferation via CBRs. Inhibitors of endocannabinoid inactivation may prove useful anticancer agents... - Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinomaAlessia Ligresti
Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche Pozzuoli, Italy
J Pharmacol Exp Ther 318:1375-87. 2006..Our data support the further testing of cannabidiol and cannabidiol-rich extracts for the potential treatment of cancer... - Estrogenic regulation of cholesterol biosynthesis and cell growth in DLD-1 human colon cancer cellsCaterina Messa
Laboratory of Biochemistry, National Institute for Digestive Diseases, S. de Bellis, Bari, Italy
Scand J Gastroenterol 40:1454-61. 2005..CONCLUSIONS: The results of this study suggest that estrogens regulate LDL-R and HMG-CoAR and influence cell growth and apoptosis in colon cancer cells... - N6-isopentenyladenosine arrests tumor cell proliferation by inhibiting farnesyl diphosphate synthase and protein prenylationChiara Laezza
Istituto di Endocrinologia e Oncologia Sperimentale I E O S, CNR, Bari, Italy
FASEB J 20:412-8. 2006..Our findings indicate that this isoprenoid end product might be used for antineoplastic therapy, an application emulating that of the lovastatin and/or farnesyl-transferase inhibitors.. - Reply to the letter to the editor "Long-term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer"Antonietta Santoro
Int J Cancer 123:243-4. 2008 - Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell linesMaria Notarnicola
Laboratory of Biochemistry, National Institute for Digestive Diseases S de Bellis, Castellana Grotte, Bari, Italy
Scand J Gastroenterol 43:66-72. 2008.... - Higher farnesyl diphosphate synthase activity in human colorectal cancer inhibition of cellular apoptosisMaria Notarnicola
Laboratory of Biochemistry, National Institute for Digestive Diseases, Castellana Grotte, Bari, Italy
Oncology 67:351-8. 2004.... - In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptakeEva de Lago
, Facultad de Medicina, Universidad Complutense, Ciudad Universitaria s n, Madrid 28040, Spain
Eur J Pharmacol 484:249-57. 2004.... - Possible relationship between statin use and decreased prevalence, number, and volume of thyroid nodules: a new indication for these drugs?Maurizio Bifulco
Thyroid 17:903. 2007 - In memory of Nino Salvatore: tenth anniversaryMaurizio Bifulco
Thyroid 18:91-2. 2008 - Helicobacter pylori has stimulatory effects on naive T cellsAnna Maria Malfitano
Department of Infectious Diseases and Microbiology, Hammersmith Campus, Imperial College London, London, UK
Helicobacter 11:21-30. 2006..pylori antigens identified two that produced a response in naive T cells. CONCLUSIONS: These data suggest that H. pylori possesses molecules that cause higher than expected proliferation of naive T cells...