Research Topics
| L LusaSummaryAffiliation: European Institute of Oncology Country: Italy Publications
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Detail Information
Publications
Challenges in projecting clustering results across gene expression-profiling datasetsLara Lusa
Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
J Natl Cancer Inst 99:1715-23. 2007....- Appropriateness of some resampling-based inference procedures for assessing performance of prognostic classifiers derived from microarray dataLara Lusa
Department of Experimental Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy
Stat Med 26:1102-13. 2007..Our results suggest that caution should be exercised in interpreting some of the claims of exceptional prognostic classifier performance that have been reported in prominent biomedical journals in the past few years... - Questioning the utility of pooling samples in microarray experiments with cell linesL Lusa
Department of Experimental Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Int J Biol Markers 21:67-73. 2006..These findings indicate that pooling samples in microarray experiments where the biological variability is expected to be small might not be helpful and could even decrease one's ability to identify differentially expressed genes... - Estimation of predictive accuracy in survival analysis using R and S-PLUSLara Lusa
Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
Comput Methods Programs Biomed 87:132-7. 2007..The use of the library is illustrated with examples based on a real data set... - Limits of predictive models using microarray data for breast cancer clinical treatment outcomeJames F Reid
Department of Experimental Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
J Natl Cancer Inst 97:927-30. 2005.... 
Patterns and changes in gene expression following neo-adjuvant anti-estrogen treatment in estrogen receptor-positive breast cancerVera Cappelletti
Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milano, Italy
Endocr Relat Cancer 15:439-49. 2008..Integration between neo-adjuvant therapy and transcriptional profiling has therefore the potential to identify therapeutic targets to be challenged for overcoming treatment resistance...- Subcellular localization of activated leukocyte cell adhesion molecule is a molecular predictor of survival in ovarian carcinoma patientsDelia Mezzanzanica
Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
Clin Cancer Res 14:1726-33. 2008..In a retrospective study, we investigated the prognostic impact of activated leukocyte cell adhesion molecule (ALCAM) expression in epithelial ovarian cancer... - A modified prognostic score for patients with curatively resected gastric cancerLuigi Mariani
Medical Statistics and Biometry Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano
Tumori 91:221-6. 2005..An existing prognostic score predicts survival in gastric cancer patients undergoing curative resection based on patient age, tumor site, extent of wall invasion and nodal status, categorized as simply as negative or positive... - Evaluating effectiveness of preoperative testing procedure: some notes on modelling strategies in multi-centre surveysDario Gregori
Department of Public Health and Microbiology, University of Torino, Torino, Italy
J Eval Clin Pract 14:11-8. 2008..The model is usually complicated by the fact that data are often non-homogeneous with respect to some uncontrolled variables and are correlated. The most typical example is the so-called hospital effect in multi-centre studies... - Re: Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancerLara Lusa
J Natl Cancer Inst 100:752-3; author reply 753-4. 2008