Mattia Intra

Summary

Affiliation: European Institute of Oncology
Country: Italy

Publications

  1. ncbi request reprint Second biopsy of axillary sentinel lymph node for reappearing breast cancer after previous sentinel lymph node biopsy
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti, 435, 20141, Milan, Italy
    Ann Surg Oncol 12:895-9. 2005
  2. doi request reprint Local therapy for breast cancer in malignant lymphoma survivors
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast 20:S99-103. 2011
  3. ncbi request reprint Axillary sentinel lymph node biopsy in patients with pure ductal carcinoma in situ of the breast
    Mattia Intra
    Department of Breast Surgery, European Institute of Oncology, Milan, Italy
    Arch Surg 138:309-13. 2003
  4. ncbi request reprint A rare association of synchronous intraductal carcinoma of the breast and invasive carcinoma of ectopic breast tissue of the vulva: case report and literature review
    M Intra
    Division of Breast Surgery, University of Milan School of Medicine, Milano, Italy
    Int J Gynecol Cancer 16:428-33. 2006
  5. ncbi request reprint Clinicopathologic characteristics of 143 patients with synchronous bilateral invasive breast carcinomas treated in a single institution
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Cancer 101:905-12. 2004
  6. ncbi request reprint Full-dose intraoperative radiotherapy with electrons in breast surgery: broadening the indications
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Arch Surg 140:936-9. 2005
  7. ncbi request reprint Sentinel lymph node metastasis in microinvasive breast cancer
    Mattia Intra
    Department of Surgery, Breast Unit, University of Milan School of Medicine, Milan, Italy
    Ann Surg Oncol 10:1160-5. 2003
  8. pmc A new option for early breast cancer patients previously irradiated for Hodgkin's disease: intraoperative radiotherapy with electrons (ELIOT)
    Mattia Intra
    Department of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast Cancer Res 7:R828-32. 2005
  9. ncbi request reprint Intraoperative radiotherapy during breast conserving surgery in patients previously treated with radiotherapy for Hodgkin's disease
    Mattia Intra
    Department of Breast Surgery, University of Milan, Italy
    Tumori 90:13-6. 2004
  10. doi request reprint Sentinel node biopsy is not a standard procedure in ductal carcinoma in situ of the breast: the experience of the European institute of oncology on 854 patients in 10 years
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Ann Surg 247:315-9. 2008

Detail Information

Publications104 found, 100 shown here

  1. ncbi request reprint Second biopsy of axillary sentinel lymph node for reappearing breast cancer after previous sentinel lymph node biopsy
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti, 435, 20141, Milan, Italy
    Ann Surg Oncol 12:895-9. 2005
    ..Although a previous SLNB is often considered a contraindication for a subsequent SLNB, few data support this concern...
  2. doi request reprint Local therapy for breast cancer in malignant lymphoma survivors
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast 20:S99-103. 2011
    ..We performed a retrospective review to assess the potential of performing breast conservative surgery and intraoperative radiotherapy with electrons (ELIOT), in these patients...
  3. ncbi request reprint Axillary sentinel lymph node biopsy in patients with pure ductal carcinoma in situ of the breast
    Mattia Intra
    Department of Breast Surgery, European Institute of Oncology, Milan, Italy
    Arch Surg 138:309-13. 2003
    ....
  4. ncbi request reprint A rare association of synchronous intraductal carcinoma of the breast and invasive carcinoma of ectopic breast tissue of the vulva: case report and literature review
    M Intra
    Division of Breast Surgery, University of Milan School of Medicine, Milano, Italy
    Int J Gynecol Cancer 16:428-33. 2006
    ..The presence of a pure DCIS of the breast makes this case really unique, definitively confirming the independent primary origin of both mammary tumors. The inguinal sentinel node biopsy avoided a bilateral inguinal dissection...
  5. ncbi request reprint Clinicopathologic characteristics of 143 patients with synchronous bilateral invasive breast carcinomas treated in a single institution
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Cancer 101:905-12. 2004
    ..Synchronous bilateral invasive breast carcinoma (SBIBC) ranged in incidence from 0.3% to as high as 12%...
  6. ncbi request reprint Full-dose intraoperative radiotherapy with electrons in breast surgery: broadening the indications
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Arch Surg 140:936-9. 2005
    ....
  7. ncbi request reprint Sentinel lymph node metastasis in microinvasive breast cancer
    Mattia Intra
    Department of Surgery, Breast Unit, University of Milan School of Medicine, Milan, Italy
    Ann Surg Oncol 10:1160-5. 2003
    ..Sentinel lymph node biopsy (SLNB) may obviate the need for CAD in these patients without compromising the staging of the axilla and the important prognostic information...
  8. pmc A new option for early breast cancer patients previously irradiated for Hodgkin's disease: intraoperative radiotherapy with electrons (ELIOT)
    Mattia Intra
    Department of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast Cancer Res 7:R828-32. 2005
    ..Mastectomy is therefore recommended as the first option treatment in these women...
  9. ncbi request reprint Intraoperative radiotherapy during breast conserving surgery in patients previously treated with radiotherapy for Hodgkin's disease
    Mattia Intra
    Department of Breast Surgery, University of Milan, Italy
    Tumori 90:13-6. 2004
    ..Mastectomy is therefore recommended as the preferred treatment option in these women...
  10. doi request reprint Sentinel node biopsy is not a standard procedure in ductal carcinoma in situ of the breast: the experience of the European institute of oncology on 854 patients in 10 years
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Ann Surg 247:315-9. 2008
    ....
  11. ncbi request reprint When sentinel lymph node is intramammary
    Mattia Intra
    Breast Surgery Department, European Institute of Oncology, Via Ripamonti 435, Milan, MI 20141, Italy
    Ann Surg Oncol 15:1304-8. 2008
    ..Little attention has been placed to the presence of intramammary sentinel lymph nodes (intraMSLNs) on preoperative lymphoscintigraphy...
  12. ncbi request reprint Sentinel lymph node biopsy is feasible even after total mastectomy
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    J Surg Oncol 95:175-9. 2007
    ..Previous mastectomy is unanimously considered to represent an absolute technical contraindication to sentinel lymph node biopsy (SLNB)...
  13. ncbi request reprint Second axillary sentinel node biopsy for ipsilateral breast tumour recurrence
    M Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Br J Surg 94:1216-9. 2007
    ..If axillary nodes remain clinically uninvolved after a previous negative SLNB the question remains whether second SLNB is a suitable option...
  14. ncbi request reprint Surgical technique of intraoperative radiotherapy in conservative treatment of limited-stage breast cancer
    Mattia Intra
    Breast Division, University of Milan, Italy
    Arch Surg 137:737-40. 2002
    ..In our experience, IORT for limited-stage breast carcinoma is easy to perform and only briefly prolongs the duration of the surgical procedure...
  15. ncbi request reprint Surgical technique of intraoperative radiation therapy with electrons (ELIOT) in breast cancer: a lesson learned by over 1000 procedures
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, University of Milan, Milan, Italy
    Surgery 140:467-71. 2006
  16. ncbi request reprint Unnecessary axillary node dissections in the sentinel lymph node era
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti, 435, 20141 Milan, Italy
    Eur J Cancer 43:2664-8. 2007
    ..As the clinical indications to SNB are progressively extending to encompass most breast cancer patients with non-metastatic disease who were previously excluded, great effort should be made to avoid 'unnecessary ALNDs'...
  17. pmc Full-dose intraoperative radiotherapy with electrons during breast-conserving surgery: experience with 590 cases
    Umberto Veronesi
    Istituto Europeo di Oncologia, Division of Radiotherapy, Istituto Europeo di Oncologia, Milan, Italy
    Ann Surg 242:101-6. 2005
    ..The new mobile linear accelerators easily moved close to the operating table to allow the full-dose irradiation during surgery...
  18. ncbi request reprint A randomized phase II trial comparing preoperative plus perioperative chemotherapy with preoperative chemotherapy in patients with locally advanced breast cancer
    Andrea Rocca
    Unit of Research in Medical Senology, Department of Medicine, Division of Pathology, University of Milan School of Medicine, Italy
    Anticancer Drugs 17:1201-9. 2006
    ..Perioperative chemotherapy failed to show an increase in the pathological complete remission rate. A biological effect on Ki-67 expression was demonstrated...
  19. ncbi request reprint Sentinel-lymph-node biopsy as a staging procedure in breast cancer: update of a randomised controlled study
    Umberto Veronesi
    Scientific Direction, European Institute of Oncology, Milan, Italy
    Lancet Oncol 7:983-90. 2006
    ..Results of our previous trial showed that SLNB accurately screens the ALN for metastasis in breast cancers of diameter 2 mm or less. We aimed to update this trial with results from longer follow-up...
  20. ncbi request reprint Sentinel node biopsy in breast cancer: early results in 953 patients with negative sentinel node biopsy and no axillary dissection
    Umberto Veronesi
    European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Eur J Cancer 41:231-7. 2005
    ..The 5 year overall survival rate of the whole series was 98%. Patients with negative sentinel node biopsies not submitted to axillary dissection show during follow-up a rate of overt axillary metastases that is lower than that expected...
  21. doi request reprint Invasive ductal carcinoma of the breast with the "triple-negative" phenotype: prognostic implications of EGFR immunoreactivity
    Giuseppe Viale
    Division of Pathology, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 116:317-28. 2009
    ..EGFR immunoreactivity significantly correlates with worse prognosis in patients with triple-negative IDC, supporting further studies on the correlation between the degree of EGFR expression and outcome of triple negative breast cancer...
  22. doi request reprint Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT): a randomised controlled equivalence trial
    Umberto Veronesi
    Scientific Directorate, European Institute of Oncology, Milan, Italy Electronic address
    Lancet Oncol 14:1269-77. 2013
    ..However, its ability to control for recurrence of local disease required confirmation in a randomised controlled trial...
  23. doi request reprint Positive axillary sentinel lymph node: is axillary dissection always necessary?
    Viviana Galimberti
    Division ofSenology, European Institute of Oncology, Milan, Italy
    Breast 20:S96-8. 2011
    ..Ancillary analyses of the IBCSG 23-01 and AMAROS trials, still in follow-up, may be able to do this...
  24. doi request reprint Can we avoid axillary dissection in the micrometastatic sentinel node in breast cancer?
    Viviana Galimberti
    Division of Senology, Unit of Molecular Senology, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy
    Breast Cancer Res Treat 131:819-25. 2012
    ..Nevertheless, a subset of patients might be at high risk of developing overt axillary disease and efforts should be made to identify such patients by ancillary analyses of the results of ongoing or recently published clinical trials...
  25. ncbi request reprint Conservative treatment of breast cancer: its evolution
    Alberto Luini
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 94:195-8. 2005
    ..From an oncological perspective, outcome was found to be equally effective, and this key observation provided us with significant impetus to investigate the effects of reducing the radiotherapy field...
  26. ncbi request reprint Nipple-sparing mastectomy in association with intra operative radiotherapy (ELIOT): A new type of mastectomy for breast cancer treatment
    Jean Yves Petit
    Division of Plastic Surgery, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 96:47-51. 2006
    ..In fact, although removal of the NAC greatly increases the patient's sensation of mutilation, and the risk of tumor involvement of the areola is reported as a very variable percentage, NAC excision still remains the standard treatment...
  27. ncbi request reprint Real-time in vivo dosimetry using micro-MOSFET detectors during intraoperative electron beam radiation therapy in early-stage breast cancer
    Mario Ciocca
    Department of Medical Physics, European Institute of Oncology, Milano, Italy
    Radiother Oncol 78:213-6. 2006
    ..In the present study, a further step was made, aiming at the improvement of the effectiveness of in vivo dosimetry, based on a real-time check of the dose...
  28. ncbi request reprint Sentinel lymph node biopsy in male patients with early breast cancer
    Oreste Gentilini
    Division of Breast Surgery, European Institute of Oncology, 20141, Milan, Italy
    Oncologist 12:512-5. 2007
    ..After a median follow-up of 30 months (range, 1-63) no axillary reappearance of the disease occurred. As with women, we recommend SLNB in male patients with breast cancer and clinically negative axilla...
  29. ncbi request reprint A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer
    Umberto Veronesi
    Division of Senology, European Institute of Oncology, Milan, Italy
    N Engl J Med 349:546-53. 2003
    ..Although numerous studies have shown that the status of the sentinel node is an accurate predictor of the status of the axillary nodes in breast cancer, the efficacy and safety of sentinel-node biopsy require validation...
  30. doi request reprint Sentinel lymph node biopsy in breast cancer: ten-year results of a randomized controlled study
    Umberto Veronesi
    European Institute of Oncology, Milan, Italy
    Ann Surg 251:595-600. 2010
    ..We present 10-year follow-up of our single-institute trial designed to compare outcomes in patients who received no axillary dissection if the sentinel node was negative, with patients who received complete axillary dissection...
  31. doi request reprint Intraoperative radiotherapy during breast conserving surgery: a study on 1,822 cases treated with electrons
    Umberto Veronesi
    European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Breast Cancer Res Treat 124:141-51. 2010
    ..4 and 89.7%. ELIOT appears a promising feature in early breast cancer treated with breast conserving surgery, reducing the exposure of normal tissues to radiations and shortening the radiation course from 6 weeks to one single session...
  32. doi request reprint Ductal intraepithelial neoplasia: postsurgical outcome for 1,267 women cared for in one single institution over 10 years
    Aliana Guerrieri-Gonzaga
    Division of Cancer Prevention and Genetics, European Institute of Oncology, Milan, Italy
    Oncologist 14:201-12. 2009
    ..We analyzed risk factors and treatment outcome in a large series of women treated at one institution...
  33. doi request reprint Do clinicopathological features of the cancer patient relate with nipple areolar complex necrosis in nipple-sparing mastectomy?
    Visnu Lohsiriwat
    Division of Plastic Surgery, European Institute of Oncology, Milan, Italy
    Ann Surg Oncol 20:990-6. 2013
    ..The main complication of NSM is nipple areolar complex (NAC) necrosis, and it is usually related to surgical technique. However, the patients' clinicopathological factors should be also considered...
  34. ncbi request reprint Ipsilateral breast tumor reappearance in patients treated with conservative surgery after primary chemotherapy. The role of surgical margins on outcome
    Oreste Gentilini
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    J Surg Oncol 94:375-9. 2006
    ..To evaluate the ipsilateral breast tumor reappearance (IBTR) rate after breast conservative surgery (BCS) following primary chemotherapy (PC) and to assess whether positive margins affects IBTR rate and overall survival (OS)...
  35. doi request reprint Breast-conserving surgery in 201 very young patients (<35 years)
    Oreste Gentilini
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, Milan, Italy
    Breast 19:55-8. 2010
    ..Surgical treatment of breast cancer in very young patients (<35 years) is still a matter of debate, since age is a predictive factor of local recurrence after breast conservation...
  36. doi request reprint Increasing steroid hormone receptors expression defines breast cancer subtypes non responsive to preoperative chemotherapy
    Marco Colleoni
    Department of Medicine, Research Unit in Medical Senology, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 116:359-69. 2009
    ..4, 95% CI 3.5-11.6, for DFS; HR 3.6 95% CI 2.4-5.6 for OS). Response and outcome after PCT are correlated with the degree of expression of steroid hormone receptors. Studies on tailored preoperative therapies are needed...
  37. doi request reprint Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial
    Viviana Galimberti
    Molecular Senology Unit, Senology Division, European Institute of Oncology, Milan, Italy
    Lancet Oncol 14:297-305. 2013
    ..We designed IBCSG trial 23-01 to determine whether no axillary dissection was non-inferior to axillary dissection in patients with one or more micrometastatic (≤2 mm) sentinel nodes and tumour of maximum 5 cm...
  38. ncbi request reprint Size of breast cancer metastases in axillary lymph nodes: clinical relevance of minimal lymph node involvement
    Marco Colleoni
    Division of Medical Oncology, Department of Medicine, Istituto Europeo di Oncologia, Via Ripamonti 435, 20141, Milan, Italy
    J Clin Oncol 23:1379-89. 2005
    ....
  39. doi request reprint Metronomic chemotherapy combined with bevacizumab and erlotinib in patients with metastatic HER2-negative breast cancer: clinical and biological activity
    Emilia Montagna
    Department of Medicine, European Institute of Oncology, Milan, Italy
    Clin Breast Cancer 12:207-14. 2012
    ..The analysis of the results suggests that the metronomic chemotherapy combined with bevacizumab and erlotinib is effective and well tolerated...
  40. ncbi request reprint Intraoperative radiation therapy for breast cancer: technical notes
    Umberto Veronesi
    Breast Department, European Institute of Oncology, Milan, Italy
    Breast J 9:106-12. 2003
    ..Here we report the two different techniques in use in these trials...
  41. doi request reprint Preoperative concurrent chemo- and endocrine therapies for women with large operable breast cancer expressing steroid hormone receptors
    Rosalba Torrisi
    Research Unit in Medical Senology, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Breast 17:654-60. 2008
    ..Endocrine therapy administered together with new intravenous, containing regimens should be explored in the preoperative treatment of endocrine responsive breast cancer...
  42. ncbi request reprint Stage migration after biopsy of internal mammary chain lymph nodes in breast cancer patients
    Viviana Galimberti
    Divisions of Senology, European Institute of Oncology, Milan, Italy
    Ann Surg Oncol 9:924-8. 2002
    ..Use of lymphoscintigraphy to visualize sentinel nodes reveals that IMNs often receive lymph from the area containing the tumor...
  43. doi request reprint Preoperative therapy with trastuzumab and oral vinorelbine (+/- endocrine therapy) in patients with HER2-positive breast cancer
    Monica Iorfida
    Unit of Research in Medical Senology, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy
    Breast 19:128-32. 2010
    ..Combined trastuzumab and intravenous vinorelbine yielded high clinical activity as preoperative treatment in patients (pts) with HER 2/neu positive breast cancer...
  44. ncbi request reprint Chemotherapy is more effective in patients with breast cancer not expressing steroid hormone receptors: a study of preoperative treatment
    Marco Colleoni
    Department of Medicine, European Institute of Oncology, Milan, Italy
    Clin Cancer Res 10:6622-8. 2004
    ..The purpose of this research was to identify factors predicting response to preoperative chemotherapy...
  45. doi request reprint Influence of margin status on outcomes in lobular carcinoma: experience of the European Institute of Oncology
    Viviana Galimberti
    Division of Senology, European Institute of Oncology, University of Milan, Milan, Italy
    Ann Surg 253:580-4. 2011
    ..Our aim was to evaluate the influence of margin status on outcomes with a view assessing the appropriateness of conservative surgery in this breast cancer subtype...
  46. ncbi request reprint Breast carcinoma in elderly women: features of disease presentation, choice of local and systemic treatments compared with younger postmenopasual patients
    Roberto Gennari
    Department of Surgery, European Institute of Oncology, Milan, Italy
    Cancer 101:1302-10. 2004
    ..The aim of the study was to evaluate the relation between biologic features at first diagnosis of breast carcinoma and treatment choice for postmenopausal women > or = 50 years to optimize treatment in the elderly...
  47. ncbi request reprint The pilot trial on intraoperative radiotherapy with electrons (ELIOT): update on the results
    Alberto Luini
    Division of Breast Surgery, University of Milan, Milan, Italy
    Breast Cancer Res Treat 93:55-9. 2005
    ..At the European Institute of Oncology we started our study on ELIOT in 1999; the first step has been a phase I-II trial to test feasibility and tolerance of ELIOT in patients candidate to breast conserving surgery...
  48. ncbi request reprint Full-dose intraoperative radiotherapy with electrons during breast-conserving surgery
    Umberto Veronesi
    Office of the Scientific Director, Milan, Italy
    Arch Surg 138:1253-6. 2003
    ..Intraoperative RT delivered with electrons at the total isodose of 2100 rad (21 Gy) could in principle substitute the currently used radiation course of external RT after breast-conserving surgery in selected cases...
  49. ncbi request reprint Report on a case of breast sarcoma metastatic to the axillary lymph nodes
    Jack Antonio Diaz Brito
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Tumori 92:188-90. 2006
    ..We report a case of a 65-year-old woman affected by follicular dendritic cell sarcoma of the left breast. Six months after breast surgery she developed an axillary metastasis from the same disease...
  50. doi request reprint Conservative surgery in patients with multifocal/multicentric breast cancer
    Oreste Gentilini
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 113:577-83. 2009
    ..We retrospectively evaluate outcome of patients with MF/MC cancers who had breast conservation with specific attention on local control and predictive factors of recurrence...
  51. ncbi request reprint Primary therapy with ECF in combination with a GnRH analog in premenopausal women with hormone receptor-positive T2-T4 breast cancer
    Rosalba Torrisi
    Research Unit of Medical Senology, Department of Medicine, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Breast 16:73-80. 2007
    ..Further studies combining chemotherapy and endocrine agents are warranted in patients with hormone receptor-positive tumors...
  52. ncbi request reprint In vivo dosimetry using radiochromic films during intraoperative electron beam radiation therapy in early-stage breast cancer
    Mario Ciocca
    Department of Medical Physics, European Institute of Oncology, Via Ripamonti 435, 20141 Milano, Italy
    Radiother Oncol 69:285-9. 2003
    ..To check the dose delivered to patients during intraoperative electron beam radiation therapy (IOERT) for early breast cancer and also to define appropriate action levels...
  53. doi request reprint Risk of locoregional recurrence in patients with false-negative frozen section or close margins of retroareolar specimen in nipple-sparing mastectomy
    Maximiliano Cassilha Kneubil
    Division of Plastic Reconstruction Surgery, European Institute of Oncology, Milan, Italy
    Ann Surg Oncol 19:4117-23. 2012
    ..Our purpose was to evaluate the locoregional recurrence (LRR) of patients with false-negative, frozen-section or close margins of retroareolar specimen in nipple-sparing mastectomy (NSM) procedure...
  54. ncbi request reprint Controversies in the use of sentinel nodes: microinvasion, post surgery and after preoperative systemic treatment
    Paolo Veronesi
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast 16:S67-70. 2007
    ..Here we discuss the suitability of SLNB in the settings of microinvasive cancer, after breast or axillary surgery and after neoadjuvant chemotherapy...
  55. ncbi request reprint Angiosarcoma of the breast: the experience of the European Institute of Oncology and a review of the literature
    Alberto Luini
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy
    Breast Cancer Res Treat 105:81-5. 2007
    ..We report the experience of the European Institute of Oncology with this unusual disease from January 1996 to January 2006: sixteen patients with angiosarcoma, 9 (56%) of whom had primary AB and 7 (44%), secondary AB, are discussed...
  56. ncbi request reprint Intraoperative radiotherapy: the debate continues
    Mattia Intra
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Lancet Oncol 5:340. 2004
  57. ncbi request reprint Male breast cancer: a special therapeutic problem. Anything new? (Review)
    Roberto Gennari
    Department of Surgery, European Institute of Oncology, 20141 Milano, Italy
    Int J Oncol 24:663-70. 2004
    ....
  58. ncbi request reprint Analysis of irradiated lung and heart volumes using virtual simulation in postoperative treatment of stage I breast carcinoma
    Maria Cristina Leonardi
    Radiation Oncology Division, European Institute of Oncology, Milan, Italy
    Tumori 89:60-7. 2003
    ....
  59. doi request reprint Immediate breast reconstruction with expander in pregnant breast cancer patients
    Visnu Lohsiriwat
    Division of Plastic Surgery, European Institute of Oncology, Via Ripamonti, 435 20141 Milano, Italy Faculty of Medicine, Mahidol University, Siriraj Hospital, Bangkok, Thailand Electronic address
    Breast 22:657-60. 2013
    ..However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation...
  60. ncbi request reprint The nipple-sparing mastectomy: early results of a feasibility study of a new application of perioperative radiotherapy (ELIOT) in the treatment of breast cancer when mastectomy is indicated
    Jean Yves Petit
    Plastic Surgery Division, European Institute of Oncology, Milan, Italy
    Tumori 89:288-91. 2003
    ..The nipple-sparing mastectomy is performed leaving 5 mm of glandular tissue behind the nipple areola complex to preserve its blood supply. The reconstruction is immediately performed with a prosthesis or an autologous flap...
  61. doi request reprint Weekly epirubicin in the treatment of gestational breast cancer (GBC)
    Fedro A Peccatori
    Department of Medicine, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy
    Breast Cancer Res Treat 115:591-4. 2009
    ..GBC is a rare disease and chemotherapy in this setting lacks a standardized approach...
  62. ncbi request reprint Radioguided occult lesion localisation (ROLL) and surgical biopsy in breast cancer. Technical aspects
    C De Cicco
    Nuclear Medicine, Radiology, Senology and Pathology Divisions, European Institute of Oncology, Milan, Italy
    Q J Nucl Med 46:145-51. 2002
    ..In this paper technical aspects of ROLL and results on a large series of patients are reported...
  63. ncbi request reprint [Intraoperative radiotherapy (IORT) in treatment of breast carcinoma--a new therapeutic alternative within the scope of breast-saving therapy? Current status and future prospects. Report of experiences from the European Institute of Oncology (EIO), Mailan
    W Gatzemeier
    Division of Senology, European Institute of Oncology, Milan, Italy
    Strahlenther Onkol 177:330-7. 2001
    ..In published series it has been demonstrated that the external boost can be replaced by intraoperative radiotherapy (IORT) where irradiation at a single dose from 10 up to 15 Gy was safely delivered directly to the tumor bed...
  64. ncbi request reprint Technical tricks to improve the cosmetic results of breast-conserving treatment
    Jean Yves Petit
    European Institute of Oncology, Department of Plastic and Reconstructive Surgery, Milan, Italy
    Breast 16:13-6. 2007
    ....
  65. ncbi request reprint Adenomyoepithelioma of the breast, presenting as a cancer
    Giovanna Gatti
    Senology Division, European Oncology Institute, Milan, Italy
    Tumori 90:337-9. 2004
    ..Adenomyoepithelioma is a rare lesion that can involve the breast tissue. The diagnostic appearance of the lesion can give rise to a difficult differential diagnosis with breast carcinoma...
  66. ncbi request reprint Selective sentinel lymph node biopsy and primary systemic therapy in breast cancer
    Antonio Piñiero
    Department of Surgery, Virgen de la Arrixaca University Hospital, Murcia, Italy
    Tumori 96:17-23. 2010
    ..Timing and influence on sentinel lymph node biopsy result by primary systemic therapy are current and controversial topics...
  67. ncbi request reprint Preliminary results on safety and activity of a randomized, double-blind, 2 x 2 trial of low-dose tamoxifen and fenretinide for breast cancer prevention in premenopausal women
    Aliana Guerrieri-Gonzaga
    Division of Chemoprevention, European Institute of Oncology, Milan, Italy
    J Clin Oncol 24:129-35. 2006
    ....
  68. ncbi request reprint Sentinel lymph node biopsy and axillary dissection in breast cancer: results in a large series
    U Veronesi
    Senology Division, Istituto Europeo di Oncologia, Milan, Italy
    J Natl Cancer Inst 91:368-73. 1999
    ....
  69. doi request reprint A risk score to predict disease-free survival in patients not achieving a pathological complete remission after preoperative chemotherapy for breast cancer
    M Colleoni
    Department of Medicine, Division of Medical Oncology, European Institute of Oncology, Milan, Italy
    Ann Oncol 20:1178-84. 2009
    ..We aimed to predict disease-free survival (DFS) in patients who failed to achieve a pathologic complete remission (pCR) after preoperative chemotherapy (PC)...
  70. ncbi request reprint Very young women (<35 years) with operable breast cancer: features of disease at presentation
    M Colleoni
    Department of Medicine, European Institute of Oncology, Milan, Italy
    Ann Oncol 13:273-9. 2002
    ..Breast cancer rarely occurs in young women. Our knowledge about disease presentation, prognosis and treatment effects are largely dependent upon older series...
  71. ncbi request reprint Chemotherapy with vinorelbine, cisplatin and continuous infusion of 5-fluorouracil in locally advanced breast cancer: a promising low-toxic regimen
    L Orlando
    Division of Medical Oncology, European Institute of Oncology, Milan, Italy
    Anticancer Res 21:4135-9. 2001
    ....
  72. ncbi request reprint Internal mammary node lymphoscintigraphy and biopsy in breast cancer
    G Paganelli
    Divisions of Nuclear Medicine, European Institute of Oncology, Milan, Italy
    Q J Nucl Med 46:138-44. 2002
    ..We investigated whether deep injection of tracer visualized internal mammary chain lymph (IMC) nodes more often, and assessed the impact of IMC status on disease staging...
  73. ncbi request reprint Optimised nuclear medicine method for tumour marking and sentinel node detection in occult primary breast lesions
    C De Cicco
    Division of Nuclear Medicine, European Institute of Oncology and University of Milan, Milan, Italy
    Eur J Nucl Med Mol Imaging 31:349-54. 2004
    ....
  74. doi request reprint Unavoidable mastectomy for ipsilateral breast tumour recurrence after conservative surgery: patient outcome
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Ann Oncol 20:1008-12. 2009
    ..In the case of ipsilateral breast tumour recurrence (IBTR) after breast-conserving surgery (BCS), a second conservative surgical approach maybe considered in some motivated patients whereas in others mastectomy is unavoidable...
  75. ncbi request reprint Breast cancer diagnosed during pregnancy and lactation: biological features and treatment options
    O Gentilini
    Department of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Eur J Surg Oncol 31:232-6. 2005
    ..Assessment of biological features and treatment of patients with breast cancer presenting during pregnancy or lactation...
  76. ncbi request reprint Preoperative systemic treatment: prediction of responsiveness
    M Colleoni
    Department of Medicine, European Institute of Oncology, Milan, Italy
    Breast 12:538-42. 2003
    ..g. endocrine primary therapy) might be more useful...
  77. ncbi request reprint Minimal and small size invasive breast cancer with no axillary lymph node involvement: the need for tailored adjuvant therapies
    M Colleoni
    Division of Medical Oncology, Department of Medicine, European Institute of Oncology, Milan, Italy
    Ann Oncol 15:1633-9. 2004
    ..While data exist to clearly correlate small tumor size to better prognosis, the fact that very small breast cancers may express biological markers of dire prognosis leads many to ignore small tumor size during treatment decision-making...
  78. pmc Factors that predict early treatment failure for patients with locally advanced (T4) breast cancer
    E Montagna
    Research Unit in Medical Senology, Department of Medicine, European Institute of Oncology, Milan, Italy
    Br J Cancer 98:1745-52. 2008
    ..High degree of Ki-67 staining and presence of PVI were also indicators of higher risk of early relapse. These factors should be considered in therapeutic algorithms for LABC...
  79. ncbi request reprint Role of endocrine responsiveness and adjuvant therapy in very young women (below 35 years) with operable breast cancer and node negative disease
    M Colleoni
    Research Unit in Medical Senology, Department of Medicine, Instituto Europeo di Oncologia, Milan, Italy
    Ann Oncol 17:1497-503. 2006
    ..There is limited knowledge about prognosis, and treatment effects in young women with node-negative disease...
  80. ncbi request reprint Is avoiding post-mastectomy radiotherapy justified for patients with four or more involved axillary nodes and endocrine-responsive tumours? Lessons from a series in a single institution
    O Gentilini
    Division of Breast Surgery, European Institue of Oncology, Milan, Italy
    Ann Oncol 18:1342-7. 2007
    ..The aim of this study was to describe outcomes of patients who underwent mastectomy without radiotherapy in a single institution...
  81. ncbi request reprint Response to primary chemotherapy in breast cancer patients with tumors not expressing estrogen and progesterone receptors
    M Colleoni
    Division of Medical Oncology, Istituto Europeo di Oncologia, Milan, Italy
    Ann Oncol 11:1057-9. 2000
    ..To test this hypothesis we evaluated the responsiveness to preoperative chemotherapy in patients with ER and progesterone receptors (PgR)-absent tumors...
  82. ncbi request reprint Prognostic role of the extent of peritumoral vascular invasion in operable breast cancer
    M Colleoni
    Research Unit in Medical Senology at the Department of Medicine, Istituto Europeo di Oncologia, Milan, Italy
    Ann Oncol 18:1632-40. 2007
    ..4%), focal (368, 14.1%), moderate (51, 2.0%) and extensive (170, 6.5%)...
  83. ncbi request reprint A comparative study on the value of FDG-PET and sentinel node biopsy to identify occult axillary metastases
    U Veronesi
    Division of Senology, European Institute of Oncology, Milan, Italy
    Ann Oncol 18:473-8. 2007
    ..The aim of this study was to compare SNB and -positron emission tomography (-PET) imaging, to assess their values in detecting occult axillary metastases...
  84. ncbi request reprint Expression of ER, PgR, HER1, HER2, and response: a study of preoperative chemotherapy
    M Colleoni
    Unit of Research in Medical Senology, Division of Medical Oncology, Department of Medicine, European Institute of Oncology, Milan, Italy
    Ann Oncol 19:465-72. 2008
    ..To identify the role of estrogen (ER), progesterone (PgR), epidermal growth factor 1 (HER1), and HER2 receptors in predicting response to preoperative chemotherapy...
  85. ncbi request reprint When can a second conservative approach be considered for ipsilateral breast tumour recurrence?
    O Gentilini
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Ann Oncol 18:468-72. 2007
    ..Mastectomy is considered the treatment of choice in patients with ipsilateral breast tumour recurrence (IBTR) after breast-conserving surgery (BCS)...
  86. ncbi request reprint [Conservative approach for breast cancer. The experience of the European Institute of Oncology]
    O Gentilini
    Divisione di Senologia, Istituto Europeo di Oncologia di Milano, Milano
    Minerva Chir 62:447-58. 2007
    ..This conservative approach is completed by the possibility to deliver a partial breast irradiation and to provide patients with more personalized adjuvant treatments tailored on the biological features of the tumour...
  87. ncbi request reprint A phase II study of primary dose-dense sequential doxorubicin plus cyclophosphamide and docetaxel in cT4 breast cancer
    R Torrisi
    Medical Senology Research Unit, Department of Medicine, Istituto Europeo di Oncologia, Via Ripamonti 435, 20141, Milan, Italy
    Anticancer Res 26:3861-4. 2006
    ..Dose-dense chemotherapy with anthracyclines and taxanes has improved either disease free survival or overall survival in high risk patients with early breast cancer...
  88. ncbi request reprint Preoperative and perioperative chemotherapy with 5-fluorouracil as continuous infusion in operable breast cancer expressing a high proliferation fraction: cytotoxic treatment during the surgical phase
    M Colleoni
    Department of Medicine, University of Milan School of Medicine, European Institute of Oncology, Milan, Italy
    Ann Oncol 14:1477-83. 2003
    ....
  89. ncbi request reprint Intraoperative radiation therapy with electrons (ELIOT) in early-stage breast cancer
    R Orecchia
    Division of Radiation Therapy, European Institute of Oncology, Milan, Italy
    Breast 12:483-90. 2003
    ..More than 400 patients have been enrolled. In addition a new approach for nipple and areola complex conservation, including ELIOT, is under investigation...
  90. ncbi request reprint The Veronesi quadrantectomy: an established procedure for the conservative treatment of early breast cancer
    S Zurrida
    Division of Senology, Istituto Europeo di Oncologia, Milan, Italy
    Int J Surg Investig 2:423-31. 2001
    ..The article goes on to describe the surgical procedures of quadrantectomy and complete axillary dissection as developed by Veronesi, and outlines new indications for, and developments of this established conservative technique...
  91. ncbi request reprint A preliminary report of intraoperative radiotherapy (IORT) in limited-stage breast cancers that are conservatively treated
    U Veronesi
    Radiotherapy Division, Istituto Europeo di Oncologia, University of Milan, Via G Ripamonti 435, 20141 Milan, Italy
    Eur J Cancer 37:2178-83. 2001
    ..However, a longer follow-up is needed for a better evaluation of the possible late side-effects...
  92. doi request reprint Minimal axillary lymph node involvement in breast cancer has different prognostic implications according to the staging procedure
    E Montagna
    Research Unit in Medical Senology, Department of Medicine, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy
    Breast Cancer Res Treat 118:385-94. 2009
    ..Treatment recommendations for systemic therapy should not take into account the presence of a single micrometastatic lymph node identified during complete serial sectioning of sentinel node(s)...
  93. doi request reprint Chemoendocrine compared with endocrine adjuvant therapies for node-negative breast cancer: predictive value of centrally reviewed expression of estrogen and progesterone receptors--International Breast Cancer Study Group
    Giuseppe Viale
    Division of Pathology and Laboratory Medicine, European Institute of Oncology, University of Milan, Milan, Italy
    J Clin Oncol 26:1404-10. 2008
    ....
  94. pmc Prognostic and predictive value of centrally reviewed Ki-67 labeling index in postmenopausal women with endocrine-responsive breast cancer: results from Breast International Group Trial 1-98 comparing adjuvant tamoxifen with letrozole
    Giuseppe Viale
    Division of Pathology and Laboratory Medicine, European Institute of Oncology, University of Milan, Milan, Italy
    J Clin Oncol 26:5569-75. 2008
    ..To evaluate the prognostic and predictive value of Ki-67 labeling index (LI) in a trial comparing letrozole (Let) with tamoxifen (Tam) as adjuvant therapy in postmenopausal women with early breast cancer...
  95. ncbi request reprint Breast conservative treatment in association with implant augmentation and intraoperative radiotherapy
    M Rietjens
    Department of Plastic and Reconstructive Surgery, European Institute of Oncology, EIO, Via Ripamonti 435, 20141 Milan, Italy
    J Plast Reconstr Aesthet Surg 59:532-5. 2006
    ..Cosmetic results are excellent and the patient is very satisfied. The surgical technique and the possible advantage of such a procedure are also discussed...
  96. ncbi request reprint Sentinel lymph node biopsy in multicentric breast cancer. The experience of the European Institute of Oncology
    O Gentilini
    Division of Senology, European Institute of Oncology, Milano, Italy
    Eur J Surg Oncol 32:507-10. 2006
    ..To present our experience with sentinel lymph node biopsy (SLNB) performed in patients with multicentric breast cancer...
  97. doi request reprint Role of breast surgery in T1-3 breast cancer patients with synchronous bone metastases
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 138:303-10. 2013
    ..In this large and homogeneous series of MBC patients with synchronous bone metastases, the role of breast surgery had a favorable impact on both disease progression and mortality...
  98. ncbi request reprint Long-term oncological results of breast conservative treatment with oncoplastic surgery
    M Rietjens
    Department of Plastic and Reconstructive Surgery, European Institute of Oncology, Milan, Italy
    Breast 16:387-95. 2007
    ..53%). Patients with tumours larger than 2 cm were at greater risk of local recurrences and distant metastasis. Long-term oncologic results of BCT with oncoplastic surgery are comparable with the results of BCT randomized trials...
  99. ncbi request reprint Sentinel lymph node biopsy for localised ductal carcinoma in situ?
    P Veronesi
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti, 435, 20141 Milan, Italy
    Breast 14:520-2. 2005
    ..If the SLN is micrometastatic complete axillary dissection is not unavoidable...
  100. ncbi request reprint Re: Trends in the treatment of ductal carcinoma in situ of the breast
    Mattia Intra
    J Natl Cancer Inst 96:1110-1. 2004
  101. ncbi request reprint Pathologic and biological prognostic factors of breast cancers in short- and long-term hormone replacement therapy users
    Virgilio Sacchini
    Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg Oncol 9:266-71. 2002
    ..Breast cancer tumors occurring in hormone replacement therapy (HRT) users are less aggressive, but no studies have compared tumor aggressiveness among HRT users by length and mode of therapy...