Nicola Fazio

..NEC are a category of NET that should be deeply studied to verify if the response to cisplatin/etoposide is homogeneous related to the different Ki67, different morphology and/or different primary site...

..Sunitinib data have been presented at the last ASCO in June 2010, and everolimus data will be presented at next ESMO in September 2010...

..The aim of this study was to evaluate the activity and safety of giving HIAC through a percutaneous catheter in pre-treated patients...

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..To investigate feasibility, morbidity and surgical mortality of a docetaxel-based chemotherapy regimen randomly administered before or after gastrectomy in patients suffering from locally-advanced resectable gastric cancer...

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..Second-line chemotherapy in patients with metastatic gastric cancer (MGC) pre-treated with cisplatin is not a standard option. We studied a combination of irinotecan, fluorouracil and folates...

..Though totally implantable access ports (TIAP) are extensively used, information from randomized trials about the impact of insertion site on patient's quality of life (QoL) and psychological distress is unavailable...

..This study evaluates the surgical morbidity and long-term outcome of colorectal cancer surgery in an unselected group of patients treated over the period 1994-2003...

..Primary liver tumours (PLTs) are currently a major health problem worldwide. The study's aim was to investigate the feasibility, toxicity, and activity of hepatic intra-arterial chemotherapy (HIAC) in patients with advanced PLTs...

..Both patients experienced minimal toxicity, suggesting that SO can be safely administered to elderly patients...

..This study reviewed the results of surgery for distal rectal cancer (where the tumour was within 6 cm of the anal verge) following the introduction of total mesorectal excision for rectal cancer in one institution...

..It is suggested that an aggressive regimen like ECF should be considered in fit patients who are not affected by concomitant liver disease...

..The objective of the study was to evaluate the role of perfusion computed tomography (CT) for monitoring and predicting therapy response in patients with hepatocellular carcinoma treated with thalidomide...

..The available therapies do not improve the poor prognosis and it is difficult to find long-term survivors (more than 1 year), even after demolitive surgery with complementary therapies...

..HIFU is likely to be a valid alternative for symptoms control in patients with pancreatic NETs. However, currently the procedure should be reserved for inoperable patients for whom symptoms cannot be controlled by medical therapy...

..This study analyzed the results of treatment of rectal cancer (tumor within 12 cm of the anal verge) with different techniques...

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..This study evaluates alternative energy sources in sealing ductal structures for use in liver resection with minimal blood loss...

..Central venous access is extensively used in oncology, though practical information from randomized trials on the most convenient insertion modality and site is unavailable...

..Main biological objective was to assess sEGFR as surrogate marker of tyrosine kinase inhibition and as predictor of response...

..The aim of this study was to analyze a homogeneous cohort of patients in order to evaluate the evolution and management of this complication...

..A promising regimen including 5-Fluorouracil, methotrexate and oxaliplatin is reported...

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..Based on the favourable behaviour of this neoplasm, we performed an endoscopic and clinical follow-up in 11 patients affected by type 1 gastric neuroendocrine tumours, avoiding any specific treatment...

..8% test accuracy. The method proposed demonstrated to be specific, accurate, and at relatively low cost but limited by low sensitivity in detecting the presence of neoplastic cells in patients with resectable non-small cell lung cancer...

..a.) chemotherapy and chemoembolization in unresectable hepatocellular carcinoma. We therefore evaluated a new program combining three courses of i.a. chemotherapy with chemoembolization administered every 28 days...

..The aim of this prospective phase I-II study was to evaluate the toxicity and efficacy of (177)Lu-DOTATATE in multiple cycles...

..We therefore evaluated the efficacy of an ITC regimen for patients presenting with carcinomatous meningitis from breast cancer...

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..Therefore, this setting should stimulate studies with new drugs and combinations and potential biological predictive factors...

..To compare the short- and long-term outcome of older and younger patients with advanced colorectal cancer who underwent elective surgery...

..Adriamycin (ADM) and ifosfamide (IFO) are the two most active agents in the treatment of soft tissue sarcomas (STS) with a clear dose-response relationship. We evaluated the feasibility and toxicity of a high-dose IFO-plus-ADM combination...

..HCC patients should be evaluated within clinical trials, possibly randomised and with homogeneous prognostic factors, in order that we may find the answer to all these important questions...

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..ECF is an active regimen in advanced gastric adenocarcinoma (GAC). We used ECF as an adjuvant therapy in a cohort of patients with GAC who underwent curative surgery and describe their results in terms of feasibility and outcome...

..The future results of the above phase III studies could indicate docetaxel as a key drug to improve treatment of patients with advanced gastric cancer...

..0001) correlated significantly with overall survival rates in the elderly. Colorectal surgery for malignancy can be performed safely in the elderly with acceptable morbidity and mortality rates and long-term survival...