Research Topics
Genomes and GenesSpecies | Fabrizio d'Adda di FagagnaSummaryAffiliation: European Institute of Oncology Country: Italy Publications
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Detail Information
Publications
Living on a break: cellular senescence as a DNA-damage responseFabrizio d'Adda di Fagagna
IFOM Foundation, FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy
Nat Rev Cancer 8:512-22. 2008....
Site-specific DICER and DROSHA RNA products control the DNA-damage responseSofia Francia
IFOM Foundation FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy
Nature 488:231-5. 2012..Our results describe an unanticipated direct role of a novel class of ncRNAs in the control of DDR activation at sites of DNA damage...
Is cellular senescence an example of antagonistic pleiotropy?Stefano Giaimo
IFOM Foundation The FIRC Institute of Molecular Oncology Foundation via Adamello 16, 20139 Milan, Italy
Aging Cell 11:378-83. 2012....
Never-ageing cellular senescenceMüge Oğrünç
IFOM Foundation, FIRC Institute of Molecular Oncology Foundation, Milan, Italy
Eur J Cancer 47:1616-22. 2011..In this short review, we summarise the many cellular pathways leading to cellular senescence and we discuss the latest experimental evidence and the questions emerging in the field...
SASPense and DDRama in cancer and ageingMarzia Fumagalli
Marzia Fumagalli and Fabrizio d Adda di Fagagna are at the IFOM Foundation FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy
Nat Cell Biol 11:921-3. 2009..Upstream elements of the DDR cascade are necessary for full blown SASP, and additional crosstalk occurs between the DDR and cytokine secretion...
