E Botteri

Summary

Affiliation: European Institute of Oncology
Country: Italy

Publications

  1. pmc Case mix at the European Institute of Oncology: first report of the Tumour Registry, 2000-2002
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, Milan, Italy
    Ecancermedicalscience 3:149. 2009
  2. pmc Recurrence and prognostic factors in patients with aggressive fibromatosis. The role of radical surgery and its limitations
    Emilio Bertani
    Division of General and Laparoscopic Surgery, European Institute of Oncology, Milan, Italy
    World J Surg Oncol 10:184. 2012
  3. doi request reprint Therapeutic effect of β-blockers in triple-negative breast cancer postmenopausal women
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 140:567-75. 2013
  4. doi request reprint Role of breast surgery in T1-3 breast cancer patients with synchronous bone metastases
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 138:303-10. 2013
  5. doi request reprint Biopsy of liver metastasis for women with breast cancer: impact on survival
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast 21:284-8. 2012
  6. doi request reprint Smoking and colorectal cancer: a meta-analysis
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, 20141, Milano, Italy
    JAMA 300:2765-78. 2008
  7. doi request reprint Unavoidable mastectomy for ipsilateral breast tumour recurrence after conservative surgery: patient outcome
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Ann Oncol 20:1008-12. 2009
  8. doi request reprint Analysis of local and regional recurrences in breast cancer after conservative surgery
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, Milan, Italy
    Ann Oncol 21:723-8. 2010
  9. doi request reprint Axillary lymph node involvement in women with breast cancer: does it depend on age?
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Clin Breast Cancer 10:318-21. 2010
  10. doi request reprint Cigarette smoking and adenomatous polyps: a meta-analysis
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Gastroenterology 134:388-95. 2008

Collaborators

Detail Information

Publications40

  1. pmc Case mix at the European Institute of Oncology: first report of the Tumour Registry, 2000-2002
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, Milan, Italy
    Ecancermedicalscience 3:149. 2009
    ..The purpose of this paper is to describe the development of the TR at the European Institute of Oncology (IEO), Milan, Italy, from its origin to its current applications...
  2. pmc Recurrence and prognostic factors in patients with aggressive fibromatosis. The role of radical surgery and its limitations
    Emilio Bertani
    Division of General and Laparoscopic Surgery, European Institute of Oncology, Milan, Italy
    World J Surg Oncol 10:184. 2012
    ..Surgery is still the standard treatment for aggressive fibromatosis (AF); however, local control remains a significant problem and the impact of R0 surgery on cumulative recurrence (CR) is objective of contradictory reports...
  3. doi request reprint Therapeutic effect of β-blockers in triple-negative breast cancer postmenopausal women
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 140:567-75. 2013
    ..Innovative therapeutic strategies including BBs should be urgently explored in cancer patients. ..
  4. doi request reprint Role of breast surgery in T1-3 breast cancer patients with synchronous bone metastases
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 138:303-10. 2013
    ..In this large and homogeneous series of MBC patients with synchronous bone metastases, the role of breast surgery had a favorable impact on both disease progression and mortality...
  5. doi request reprint Biopsy of liver metastasis for women with breast cancer: impact on survival
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast 21:284-8. 2012
    ..Biopsy of metastatic site of disease can influence treatment decisions, but its impact on survival remains uncertain...
  6. doi request reprint Smoking and colorectal cancer: a meta-analysis
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, 20141, Milano, Italy
    JAMA 300:2765-78. 2008
    ..Colorectal cancer is the third most common form of cancer and the fourth most frequent cause of cancer deaths worldwide. The association between cigarette smoking and colorectal cancer has been inconsistent among studies...
  7. doi request reprint Unavoidable mastectomy for ipsilateral breast tumour recurrence after conservative surgery: patient outcome
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Ann Oncol 20:1008-12. 2009
    ..In the case of ipsilateral breast tumour recurrence (IBTR) after breast-conserving surgery (BCS), a second conservative surgical approach maybe considered in some motivated patients whereas in others mastectomy is unavoidable...
  8. doi request reprint Analysis of local and regional recurrences in breast cancer after conservative surgery
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, Milan, Italy
    Ann Oncol 21:723-8. 2010
    ..A minority of patients treated conservatively for breast cancer will develop local or regional recurrences. Our aim was to determine how their occurrence may be linked to the evolution of the disease...
  9. doi request reprint Axillary lymph node involvement in women with breast cancer: does it depend on age?
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Clin Breast Cancer 10:318-21. 2010
    ..We studied the specific relationship between lymph node (LN) involvement and age...
  10. doi request reprint Cigarette smoking and adenomatous polyps: a meta-analysis
    Edoardo Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Gastroenterology 134:388-95. 2008
    ..We performed a meta-analysis to provide a quantitative pooled risk estimate of the association, focusing on the different characteristics of the study populations, study designs, and clinical feature of the polyps...
  11. doi request reprint The value of radiotherapy on metastatic internal mammary nodes in breast cancer. Results on a large series
    U Veronesi
    European Institute of Oncology, Milan, Italy
    Ann Oncol 19:1553-60. 2008
    ..We assume that this excellent result is due to radiotherapy to internal mammary nodes and we propose that exploration of internal mammary nodes should be part of the staging process of carcinomas of the medial part of the breast...
  12. pmc Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype
    M Lazzeroni
    Division of Cancer Prevention and Genetics, European Institute of Oncology, Milan, Italy
    Br J Cancer 108:1593-601. 2013
    ..The post-surgical management of ductal intraepithelial neoplasia (DIN) of the breast is still a dilemma. Ki-67 labelling index (LI) has been proposed as an independent predictive and prognostic factor in early breast cancer...
  13. doi request reprint Oncological results of immediate breast reconstruction: long term follow-up of a large series at a single institution
    J Y Petit
    Department of Plastic Surgery, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 112:545-9. 2008
    ..However, a delay in the reconstruction is usually proposed after the mastectomy in case of invasive cancer, while there is a general agreement for immediate breast reconstruction in case of in situ tumors...
  14. doi request reprint Breast cancer subtype approximations and loco-regional recurrence after immediate breast reconstruction
    M C Kneubil
    Division of Plastic Reconstruction Surgery, European Institute of Oncology, Via Ripamonti 435, 20141 Milano, Italy
    Eur J Surg Oncol 39:260-5. 2013
    ..The LRR also varies according to breast cancer subtypes and clinicopathological features...
  15. doi request reprint Evaluation of fat grafting safety in patients with intraepithelial neoplasia: a matched-cohort study
    J Y Petit
    Department of Reconstructive Surgery, European Institute of Oncology, Milan, Italy
    Ann Oncol 24:1479-84. 2013
    ..Fat grafting is widely carried out in breast cancer patients to improve quality in breast reconstruction. Recently, in vitro and animal studies have questioned the role of adipose tissues in cancer development...
  16. doi request reprint Mastectomy without radiotherapy: outcome analysis after 10 years of follow-up in a single institution
    E Botteri
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 134:1221-8. 2012
    ..PVI and Ki-67 might help tailoring PMRT indications among patients with positive LNs. Finally, the very low incidence of recurrences in the axillary LNs raises questions about the inclusion of the axilla in the radiation field...
  17. ncbi request reprint Is avoiding post-mastectomy radiotherapy justified for patients with four or more involved axillary nodes and endocrine-responsive tumours? Lessons from a series in a single institution
    O Gentilini
    Division of Breast Surgery, European Institue of Oncology, Milan, Italy
    Ann Oncol 18:1342-7. 2007
    ..The aim of this study was to describe outcomes of patients who underwent mastectomy without radiotherapy in a single institution...
  18. doi request reprint Outcome and clinical-biological characteristics of patients with advanced breast cancer undergoing removal of ovarian/pelvic metastases
    E Munzone
    Department of Medicine, Division of Medical Oncology, Istituto Europeo di Oncologia, Milano, Italy
    Ann Oncol 23:2884-90. 2012
    ..Patients with metastatic breast cancer to the ovary, without tumor debulking and after systemic therapy, have a 5-year survival rate < 10%...
  19. doi request reprint Low-dose tamoxifen in the treatment of breast ductal intraepithelial neoplasia: results of a large observational study
    A Guerrieri-Gonzaga
    Division of Cancer Prevention and Genetics, European Institute of Oncology, Milan, Italy
    Ann Oncol 21:949-54. 2010
    ..Since low-dose tamoxifen showed a favorable modulation of breast cancer biomarkers in phase II trials, a monoinstitutional cohort of women with DIN treated with low-dose tamoxifen or no systemic treatment was analyzed...
  20. doi request reprint Risk factors associated with recurrence after nipple-sparing mastectomy for invasive and intraepithelial neoplasia
    J Y Petit
    Division of Plastic Surgery, European Institute of Oncology, Milan, Italy
    Ann Oncol 23:2053-8. 2012
    ..To identify risk factors of recurrence in a large series of patients with breast cancer who underwent a nipple-sparing mastectomy (NSM)...
  21. doi request reprint Prognostic role of CA15.3 in 7942 patients with operable breast cancer
    M T Sandri
    Division of Laboratory Medicine, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
    Breast Cancer Res Treat 132:317-26. 2012
    ..3 value is an independent prognostic factor for metastases and deaths. CA15.3 provides additional information to the common prognostic factors and should be considered in the adjuvant therapeutic algorithm...
  22. ncbi request reprint When can a second conservative approach be considered for ipsilateral breast tumour recurrence?
    O Gentilini
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Ann Oncol 18:468-72. 2007
    ..Mastectomy is considered the treatment of choice in patients with ipsilateral breast tumour recurrence (IBTR) after breast-conserving surgery (BCS)...
  23. doi request reprint Impact on survival of the number of lymph nodes removed in patients with node-negative gastric cancer submitted to extended lymph node dissection
    R Biffi
    Division of Abdomino Pelvic Surgery, European Institute of Oncology, Via Ripamonti 435, I 20141 Milan, Italy
    Eur J Surg Oncol 37:305-11. 2011
    ..This study was designed to establish whether the number of lymph nodes removed has an effect on prognosis in patients with node-negative gastric cancer...
  24. ncbi request reprint Variation of circulating tumor cell levels during treatment of metastatic breast cancer: prognostic and therapeutic implications
    F Nole
    Division of Medical Oncology, Medical Care Unit, European Institute of Oncology, Milano, Italy
    Ann Oncol 19:891-7. 2008
    ..This study aimed to evaluate the prognostic significance of circulating tumor cells (CTCs) detection in advanced breast cancer patients...
  25. doi request reprint Locoregional recurrence risk after lipofilling in breast cancer patients
    J Y Petit
    Division of Plastic Surgery, European Institute of Oncology, Milan, Italy
    Ann Oncol 23:582-8. 2012
    ..The clinical literatures underline its technical efficacy but experimental studies raise important questions about the potential detrimental effect of adipocytes on the stimulation of cancer growth and reappearance...
  26. doi request reprint Prognostic value of Ki-67 labeling index in patients with node-negative, triple-negative breast cancer
    Elisabetta Munzone
    Division of Medical Oncology, Department of Medicine, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy
    Breast Cancer Res Treat 134:277-82. 2012
    ..3 (95% CI 1.0-5.8, P=0.046). Within the group of patients with node-negative TNBC, Ki-67LI was associated with different prognoses subgroups. Ki-67LI might be useful in the design of trials of risk-adapted adjuvant therapies...
  27. doi request reprint Nipple-sparing mastectomy: risk of nipple-areolar recurrences in a series of 579 cases
    J Y Petit
    Department of Plastic Surgery, European Institute of Oncology, Via Ripamonti 435, Milan, 20 141, Italy
    Breast Cancer Res Treat 114:97-101. 2009
    ..The risk of local recurrence behind the nipple areolar complex (NAC) is the main limiting factor of the NSM procedure. To minimize such risk, we proposed in 2002 a intraoperative radiotherapy of the preserved NAC...
  28. ncbi request reprint Brain metastases in patients with advanced breast cancer
    G Sanna
    Department of Oncology, European Institute of Oncology, Milan, Italy
    Anticancer Res 27:2865-9. 2007
    ..The incidence of brain metastases (BM) is apparently rising in patients with advanced breast cancer (ABC). We performed a case control study to define current features of breast cancer related to central nervous system (CNS) metastases...
  29. ncbi request reprint Ovarian metastases in early-stage cervical cancer (IA2-IIA): a multicenter retrospective study of 1965 patients (a Cooperative Task Force study)
    F Landoni
    Department of Gynecology Oncology, European Institute of Oncology EIO, Milan, Italy
    Int J Gynecol Cancer 17:623-8. 2007
    ....
  30. doi request reprint High-dose chemotherapy in relapsed or refractory Hodgkin lymphoma patients: a reappraisal of prognostic factors
    E Cocorocchio
    Haematoncology Division, European Institute of Oncology, Milan, Italy
    Hematol Oncol 31:34-40. 2013
    ..HDCT is able to induce a high remission rate and a prolonged PFS in more than 50% of the patients with refractory and relapsed HL...
  31. doi request reprint Early oral versus "traditional" postoperative feeding in gynecologic oncology patients undergoing intestinal resection: a randomized controlled trial
    L Minig
    Department of Gynecology, European Institute of Oncology, Milan, Italy
    Ann Surg Oncol 16:1660-8. 2009
    ....
  32. doi request reprint Light alcohol drinking and cancer: a meta-analysis
    V Bagnardi
    Department of Statistics, University of Milan Bicocca, Milan, Italy
    Ann Oncol 24:301-8. 2013
    ..Most of the data derive from studies that focused on the effect of moderate/high alcohol intakes, while little is known about light alcohol drinking (up to 1 drink/day)...
  33. doi request reprint Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps
    Patrick Maisonneuve
    Gastroenterology 135:710; author reply 710-1. 2008
  34. ncbi request reprint Circulating levels of VCAM and MMP-2 may help identify patients with more aggressive prostate cancer
    Concetta De Cicco
    Division of Nuclear Medicine, European Institute of Oncology, Milan, Italy
    Curr Cancer Drug Targets 8:199-206. 2008
    ..Better specific care could be provided to the aggressive phenotype-group of patients if pre-surgical identification were available...
  35. ncbi request reprint Angiosarcoma of the breast: the experience of the European Institute of Oncology and a review of the literature
    Alberto Luini
    Division of Breast Surgery, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy
    Breast Cancer Res Treat 105:81-5. 2007
    ..We report the experience of the European Institute of Oncology with this unusual disease from January 1996 to January 2006: sixteen patients with angiosarcoma, 9 (56%) of whom had primary AB and 7 (44%), secondary AB, are discussed...
  36. ncbi request reprint Can axillary and supraclavicular radiotherapy be avoided after breast-conserving surgery and axillary dissection in women with multiple involved axillary nodes? Experience at the European Institute of Oncology
    Viviana Galimberti
    Department of Senology, European Institute of Oncology, Milan, Italy
    Tumori 94:52-8. 2008
    ..We performed a retrospective analysis of patients with 4 or more axillary nodes involved and sufficient follow-up to provide indications as to whether our current treatment is adequate...
  37. ncbi request reprint Tobacco smoking and cancer: a meta-analysis
    Sara Gandini
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Int J Cancer 122:155-64. 2008
    ..The analysis of heterogeneity showed that study type, gender and adjustment for confounding factors significantly influence the RRs estimates and the reliability of the studies...
  38. ncbi request reprint Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: the experience of the European Institute of Oncology and review of the literature
    Alberto Luini
    Division of Breast Surgery, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 101:349-53. 2007
    ..The purpose of the present study was to compare the clinical course, and prognosis, between this type of tumor and poorly differentiated ductal carcinoma...
  39. ncbi request reprint Empirical-Bayes adjustment improved conventional estimates in postmarketing drug-safety studies
    Vincenzo Bagnardi
    Department of Statistics, University of Milan Bicocca, Milan, Italy
    J Clin Epidemiol 59:1162-8. 2006
    ..Empirical-Bayes adjustment was used to investigate the effects of antibacterials on risk of arrhythmia in a large cohort study based upon automated record linkage...
  40. ncbi request reprint Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis
    Debora Macis
    Division of Chemoprevention, European Institute of Oncology, Milan, Italy
    Breast Cancer Res Treat 106:263-71. 2007
    ..A reduced activity of methylenetetrahydrofolate reductase (MTHFR) due to frequent C677T polymorphism affects DNA synthesis, repair and methylation and may be implicated in breast cancer risk...