Enzo Emanuele

Summary

Country: Italy

Publications

  1. ncbi Linking atherosclerosis to Alzheimer's disease: focus on biomarkers
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Front Biosci (Elite Ed) 4:700-10. 2012
  2. ncbi Biochemical markers of impending psychosis
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Curr Pharm Des 18:505-9. 2012
  3. ncbi Raised plasma nerve growth factor levels associated with early-stage romantic love
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine, CIRMC, University of Pavia, Viale Taramelli 24, I 27100 Pavia, Italy
    Psychoneuroendocrinology 31:288-94. 2006
  4. doi NGF and romantic love
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Arch Ital Biol 149:265-8. 2011
  5. doi Adiponectin expression in subcutaneous adipose tissue is reduced in women with cellulite
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Int J Dermatol 50:412-6. 2011
  6. ncbi An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Neuro Endocrinol Lett 31:663-6. 2010
  7. ncbi Circulating levels of soluble CD26 are associated with phobic anxiety in women
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli, 24, I 27100, Pavia, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:1334-6. 2006
  8. doi Increased serum levels of high mobility group box 1 protein in patients with autistic disorder
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, via Bassi, 21, I 27100, Pavia, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 34:681-3. 2010
  9. doi Preliminary evidence of a genetic association between chromosome 9p21.3 and human longevity
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Rejuvenation Res 13:23-6. 2010
  10. ncbi Increased dopamine DRD4 receptor mRNA expression in lymphocytes of musicians and autistic individuals: bridging the music-autism connection
    Enzo Emanuele
    Department of Applied and Psychobehavioural Sciences, University of Pavia, Pavia, Italy
    Neuro Endocrinol Lett 31:122-5. 2010

Detail Information

Publications75

  1. ncbi Linking atherosclerosis to Alzheimer's disease: focus on biomarkers
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Front Biosci (Elite Ed) 4:700-10. 2012
    ..The study of specific biomarkers of atherosclerosis in AD can contribute to identify different components of the pathophysiology and the complex mechanisms underlying the progression of the disease...
  2. ncbi Biochemical markers of impending psychosis
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Curr Pharm Des 18:505-9. 2012
    ..We will also examine the practical issues that seem to be limiting the effective integration of biomarkers into clinical development...
  3. ncbi Raised plasma nerve growth factor levels associated with early-stage romantic love
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine, CIRMC, University of Pavia, Viale Taramelli 24, I 27100 Pavia, Italy
    Psychoneuroendocrinology 31:288-94. 2006
    ..Taken together, these findings suggest that some behavioural and/or psychological features associated with falling in love could be related to raised NGF levels in the bloodstream...
  4. doi NGF and romantic love
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Arch Ital Biol 149:265-8. 2011
    ..The progresses in the neurobiology of love suggest that this kind of research may open a new window onto our understanding of the very nature of human romantic bonding...
  5. doi Adiponectin expression in subcutaneous adipose tissue is reduced in women with cellulite
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Int J Dermatol 50:412-6. 2011
    ..We reasoned that a reduction in the expression of adiponectin - a humoral vasodilator - in the SAT of cellulite areas might contribute to the altered microcirculation frequently found in these regions...
  6. ncbi An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Neuro Endocrinol Lett 31:663-6. 2010
    ..Our data suggest that direct modulation of the serotonergic system may have use for the treatment of psychological suffering associated with unreciprocated romantic love...
  7. ncbi Circulating levels of soluble CD26 are associated with phobic anxiety in women
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli, 24, I 27100, Pavia, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:1334-6. 2006
    ..31 (95% CI: 0.18-0.74) for the second and 0.47 (95% CI: 0.34-0.63) for the third tertile. Altogether, our data suggest that reduced plasma sCD26 concentrations could be a marker of high levels of phobic anxiety in women...
  8. doi Increased serum levels of high mobility group box 1 protein in patients with autistic disorder
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, via Bassi, 21, I 27100, Pavia, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 34:681-3. 2010
    ..The objective of the present study was to measure serum levels of HMGB1 in patients with autistic disorder and to study their relationship with clinical characteristics...
  9. doi Preliminary evidence of a genetic association between chromosome 9p21.3 and human longevity
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Rejuvenation Res 13:23-6. 2010
    ..We hypothesized that this locus may have widespread effects on aging phenotypes and, as such, influences the ability to achieve a long and healthy life...
  10. ncbi Increased dopamine DRD4 receptor mRNA expression in lymphocytes of musicians and autistic individuals: bridging the music-autism connection
    Enzo Emanuele
    Department of Applied and Psychobehavioural Sciences, University of Pavia, Pavia, Italy
    Neuro Endocrinol Lett 31:122-5. 2010
    ..Previous studies have suggested a pivotal role for the dopaminergic system in the psychobiology of reward, including the pleasure of music...
  11. ncbi Elevated urine levels of bufotenine in patients with autistic spectrum disorders and schizophrenia
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Neuro Endocrinol Lett 31:117-21. 2010
    ..We also sought to assess whether urine concentrations of this molecule may be associated with the clinical characteristics of psychiatric patients...
  12. doi Low-grade endotoxemia in patients with severe autism
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, via Bassi, 21, I 27100, Pavia, Italy
    Neurosci Lett 471:162-5. 2010
    ..Whether increased endotoxin may contribute to the pathophysiology of inflammation and impaired reciprocal social interaction in autism should be further explored in future studies...
  13. doi A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite
    E Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    J Eur Acad Dermatol Venereol 24:930-5. 2010
    ....
  14. doi Serum levels of vascular endothelial growth factor and its receptors in patients with severe autism
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, via Bassi, 21, I 27100, Pavia, Italy
    Clin Biochem 43:317-9. 2010
    ..To study vascular endothelial growth factor (VEGF) and its soluble receptors sVEGFR-1 and -2 in autism...
  15. doi Chromosome 9p21.3 genotype is associated with vascular dementia and Alzheimer's disease
    Enzo Emanuele
    Department of Health Sciences, Section of Psychiatry, University of Pavia, via Bassi 21, Pavia, Italy
    Neurobiol Aging 32:1231-5. 2011
    ..01). Altogether, our data indicate for the first time that the C allele of rs1333049 in the vascular disease susceptibility locus is associated with VaD and LOAD, independent of traditional risk factors and the APOE ε4 genotype...
  16. doi Relationship between platelet serotonin content and rejections of unfair offers in the ultimatum game
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli 24, I 27100 Pavia, Italy
    Neurosci Lett 437:158-61. 2008
    ..Our pilot data seem to indicate that the serotonergic system may play an important role in the UG rejection behaviour...
  17. doi Serum omega-3 fatty acids are associated with ultimatum bargaining behavior
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Pavia, Italy
    Physiol Behav 96:180-3. 2009
    ..The results of this study suggest that a depletion of the serum omega-3 fatty acids is associated with rejections of unfair ultimatum offers in an experimental neuroeconomic setting...
  18. doi Serum levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with different psychiatric disorders
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Neurosci Lett 487:99-102. 2011
    ..Although subject to future confirmation, our findings suggest that the reduced serum sRAGE may contribute to increased cardiovascular risk in schizophrenia and major depression...
  19. pmc Relationship between apolipoprotein(a) size polymorphism and coronary heart disease in overweight subjects
    Enzo Emanuele
    Molecular Medicine Laboratory, IRCCS San Matteo Hospital, University of Pavia, Italy
    BMC Cardiovasc Disord 3:12. 2003
    ..The objective of this study was to evaluate lipoprotein(a) [Lp(a)] plasma levels and apolipoprotein(a) [apo(a)] phenotypes in relation to coronary heart disease (CHD) in overweight subjects...
  20. ncbi Genetic loading on human loving styles
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine, University of Pavia, Pavia, Italy
    Neuro Endocrinol Lett 28:815-21. 2007
    ....
  21. ncbi -374T/A polymorphism of the RAGE gene promoter in relation to severity of coronary atherosclerosis
    Colomba Falcone
    Department of Hematological, Pneumological and Cardiovascular Sciences, Division of Cardiology, University Hospital IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi 2, 27100 Pavia, Italy
    Clin Chim Acta 354:111-6. 2005
    ..Here we focused on the putative involvement of this functional RAGE polymorphism on the severity of coronary atherosclerosis as assessed by angiography...
  22. ncbi Relation of apolipoprotein(a) size to alzheimer's disease and vascular dementia
    Enzo Emanuele
    Molecular Medicine Laboratory, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
    Dement Geriatr Cogn Disord 18:189-96. 2004
    ..Our results demonstrate that possession of at least one LMW apo(a) isoform is significantly associated with dementia and specifically offer new evidence of a strong association between the lipoprotein system and post-stroke dementia...
  23. ncbi Genetic association of alpha2-Heremans-Schmid glycoprotein polymorphism with late-onset Alzheimer's disease in Italians
    Diego Geroldi
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli 24, 27100 Pavia, Italy
    Neurosci Lett 386:176-8. 2005
    ..0001). These results suggest that the AHSG gene polymorphism may be associated with LOAD in Italians. Additional studies are warranted to examine the biological relevance of AHSG in the pathophysiology of neurodegenerative disorders...
  24. ncbi Apolipoprotein(a) null phenotype is related to a delayed age at onset of Alzheimer's disease
    Enzo Emanuele
    Molecular Medicine Laboratory, IRCCS Policlinico San Matteo, Piazzale Golgi 2, University of Pavia, 27100 Pavia, Italy
    Neurosci Lett 357:45-8. 2004
    ..We conclude that the expression of at least one apo(a) isoform may interact with other pathogenic mechanisms involved in controlling the age at onset of AD...
  25. ncbi The T393C polymorphism of the GNAS1 gene is associated with deficit schizophrenia in an Italian population sample
    Piercarlo Minoretti
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli 24, I 27100 Pavia, Italy
    Neurosci Lett 397:159-63. 2006
    ..06 (95% confidence interval (CI): 1.21-3.47), p=0.007]. Altogether, our data suggest that the GNAS1 T393C status could influence susceptibility for deficit schizophrenia in Italian subjects...
  26. ncbi Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia
    Enzo Emanuele
    Molecular Medicine Laboratory, University of Pavia, IRCCS San Matteo Hospital, Pavia, Italy
    Arch Neurol 62:1734-6. 2005
    ..In addition, administration of sRAGE has been shown to reduce development of cerebral beta-amyloidosis in an Alzheimer disease mouse model...
  27. ncbi Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease
    Piercarlo Minoretti
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli 24, I 27100 Pavia, Italy
    Neurosci Lett 391:147-9. 2006
    ..37 (95% CI: 0.20-0.69, P=0.002). Our data further support a role for innate immunity in neurodegeneration and give the first evidence that the TLR4 Asp299Gly variant may be protective toward the development of LOAD...
  28. ncbi Significance of apolipoprotein(a) phenotypes in acute coronary syndromes: relation with clinical presentation
    Enzo Emanuele
    Molecular Medicine Laboratory, IRCCS Policlinico San Matteo, Piazzale Golgi 2, University of Pavia, 27100 Pavia, Italy
    Clin Chim Acta 350:159-65. 2004
    ..We sought to determine whether Lp(a) concentrations and apo(a) phenotypes may be related to the clinical syndrome of presentation among ACS patients...
  29. doi The -374T/A RAGE polymorphism protects against future cardiac events in nondiabetic patients with coronary artery disease
    Colomba Falcone
    Department of Cardiology, University Hospital Fondazione IRCCS San Matteo, Pavia, Italy Interdepartmental Center for Research in Prevention of Cardiovascular and Metabolic Disorders CIRMC, University of Pavia, Pavia, Italy
    Arch Med Res 39:320-5. 2008
    ..Hereto we sought to address this issue in a large consecutive cohort of patients undergoing coronary revascularization...
  30. ncbi Association between small apolipoprotein(a) isoforms and frontotemporal dementia in humans
    Enzo Emanuele
    Molecular Medicine Laboratory, IRCCS Policlinico San Matteo, Piazzale Golgi 2, University of Pavia, 27100 Pavia, Italy
    Neurosci Lett 353:201-4. 2003
    ..011 and P=0.025, respectively). Our data suggest a role of apo(a) phenotypes of low MW in mediating susceptibility to FTD...
  31. ncbi Association of plasma eotaxin levels with the presence and extent of angiographic coronary artery disease
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli 24, 27100 Pavia, Italy
    Atherosclerosis 186:140-5. 2006
    ..426, P<0.001). Our data suggest that increased eotaxin levels are associated with the presence of CAD and that circulating levels of this chemokine may reflect the extent of coronary atherosclerosis...
  32. doi Decreased NT-3 plasma levels and platelet serotonin content in patients with hypochondriasis
    Natascia Brondino
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    J Psychosom Res 65:435-9. 2008
    ..Although NTs have been associated to a variety of mental disorders, the potential role of NT alterations in hypochondriasis (HC) has never been investigated...
  33. ncbi Soluble RAGE-modulating drugs: state-of-the-art and future perspectives for targeting vascular inflammation
    Niccolò Lanati
    Department of Preventive Medicine, University of Pavia, Pavia, Italy
    Curr Vasc Pharmacol 8:86-92. 2010
    ..The present review considers current vascular drugs as modulators of the RAGE axis, and highlights future directions in the context of RAGE-directed therapy in cardiovascular disease...
  34. ncbi Alterations of circulating endogenous secretory RAGE and S100A9 levels indicating dysfunction of the AGE-RAGE axis in autism
    Marianna Boso
    Department of Applied Health and Behavioural Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Neurosci Lett 410:169-73. 2006
    ..34). Our results of a significantly reduced peripheral level of esRAGE coupled with elevated S100A9 point to a subtle but definite dysfunction of the AGEs/RAGE axis in autism that could play a role in the pathophysiology of this disorder...
  35. ncbi The M694V variant of the familial Mediterranean fever gene is associated with sporadic early-onset Alzheimer's disease in an Italian population sample
    Mariarosa Arra
    Interdepartmental Center for Research in Molecular Medicine, University of Pavia, Pavia, Italy
    Dement Geriatr Cogn Disord 23:55-9. 2007
    ..We sought to determine whether the proinflammatory M694V mutation of pyrin, the gene responsible for familial Mediterranean fever, could lead to an increased risk for AD...
  36. ncbi QT interval duration in apparently healthy men is associated with depression-related personality trait neuroticism
    Piercarlo Minoretti
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, Viale Taramelli, 24, I 27100 Pavia, Italy
    J Psychosom Res 61:19-23. 2006
    ..The question as to whether these depression-related personality domains are related to cardiac repolarization (duration of QT interval) in apparently healthy men has been addressed in this study...
  37. ncbi Elevated plasma N-terminal ProBNP levels in unmedicated patients with major depressive disorder
    Pierluigi Politi
    Department of Applied Health and Behavioural Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Neurosci Lett 417:322-5. 2007
    ..422, P=0.008) between plasma NT-proBNP and HAMD scores. Altogether, our results indicate that elevated NT-proBNP levels may play a role in linking MDD with increased cardiovascular risk...
  38. ncbi Apolipoprotein(a) phenotypes are reliable biomarkers for familial aggregation of coronary heart disease
    Emmanouil Peros
    Molecular Medicine Laboratory, IRCCS San Matteo Hospital, University of Pavia, Pavia, Italy
    Int J Mol Med 13:243-7. 2004
    ....
  39. ncbi Association analysis of the functional Ala111Glu polymorphism of the glyoxalase I gene in panic disorder
    Pierluigi Politi
    Department of Applied Health and Behavioural Sciences, Section of Psychiatry, University of Pavia, via Bassi 21, I 27100, Pavia, Italy
    Neurosci Lett 396:163-6. 2006
    ..While our data suggest that this polymorphism is unlikely to have a major function in the pathogenesis of panic disorder, it could play a role in the subgroup of patients without agoraphobic avoidance...
  40. ncbi Elevated plasma levels of lipoprotein(a) in psychiatric patients: a possible contribution to increased vascular risk
    Enzo Emanuele
    Molecular Medicine Laboratory, Clinica Medica 2, IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi, 2, 27100 Pavia, Italy
    Eur Psychiatry 21:129-33. 2006
    ..On the other hand, no differences were found among personality disorder and controls. Our findings suggest that the elevation of plasma Lp(a) may contribute to increased cardiovascular risk in several patients with psychiatric disorders...
  41. ncbi Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men
    Colomba Falcone
    Department of Cardiology, University Hospital IRCCS San Matteo, Pavia, Italy
    Arterioscler Thromb Vasc Biol 25:1032-7. 2005
    ..We sought to determine whether a decreased plasma level of sRAGE could be independently associated with the prevalence of coronary artery disease (CAD) in nondiabetic men...
  42. ncbi Seasonal fluctuations in problem behaviors among young adults with autism and intellectual disability
    Marianna Boso
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Med Sci Monit 16:CR213-6. 2010
    ..Acute behavioral alterations have been frequently reported in patients with autism. However, the question as to whether behavioral problems undergo seasonal variations in autism remains to be addressed...
  43. ncbi A W148R mutation in the human FOXD4 gene segregating with dilated cardiomyopathy, obsessive-compulsive disorder, and suicidality
    Piercarlo Minoretti
    Interdepartmental Center for Research in Molecular Medicine CIRMC, University of Pavia, I 27100, Pavia, Italy
    Int J Mol Med 19:369-72. 2007
    ..Our present findings widen the spectrum of diseases associated with genetic aberrations in the forkhead gene family...
  44. ncbi Soluble receptor for advanced glycation end products: from disease marker to potential therapeutic target
    Diego Geroldi
    Department of Internal Medicine and Medical Therapeutics, IRCCS San Matteo Hospital, Malattie Vascolari e Metaboliche, University of Pavia, Piazzale Golgi 2, 27100 Pavia, Italy
    Curr Med Chem 13:1971-8. 2006
    ....
  45. ncbi Decreased plasma levels of soluble receptor for advanced glycation end-products in patients with essential hypertension
    Diego Geroldi
    Interdepartmental Center for Research in Molecular Medicine CIRMC, Department of Internal Medicine and Medical Therapeutics, IRCCS San Matteo Hospital, University of Pavia, Piazzale Golgi 2, 27100 Pavia, Italy
    J Hypertens 23:1725-9. 2005
    ..Here we studied the plasma sRAGE levels in hypertensive and normotensive human subjects. We also investigated the relationship between blood pressure parameters and plasma sRAGE concentrations...
  46. ncbi Analysis of the apolipoprotein(a) size polymorphism in patients with systemic lupus erythematosus
    Emmanouil Peros
    Department of Internal Medicine and Medical Therapeutics, Section of Internal Medicine, Vascular and Metabolic Diseases, IRCCS San Matteo Hospital, University of Pavia, 27100 Pavia, Italy
    Int J Mol Med 15:661-5. 2005
    ..As small apo(a) phenotypes have been related to adverse vascular effects, it is feasible that small apo(a) isoforms may be a useful biological marker in the assessment of vascular risk in patients with SLE...
  47. ncbi Getting old with a new heart: impact of age on depression and quality of life in long-term heart transplant recipients
    Valentina Martinelli
    DSSAeP, Section of Psychiatry, University of Pavia, Pavia, Italy
    J Heart Lung Transplant 26:544-8. 2007
    ..The aim of the present study was to investigate the role of age on depression and quality of life in a sample of long-term heart transplant recipients...
  48. ncbi Effect of long-term interactive music therapy on behavior profile and musical skills in young adults with severe autism
    Marianna Boso
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    J Altern Complement Med 13:709-12. 2007
    ..Data on the potential behavioral effects of music therapy in autism are scarce...
  49. ncbi Reduced plasma apelin levels in patients with autistic spectrum disorder
    Marianna Boso
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Arch Med Res 38:70-4. 2007
    ..Aims of the present study were to investigate circulating levels of apelin in patients with ASD and to assess their correlation with plasma AVP concentrations...
  50. ncbi Plasma osteoprotegerin as a biochemical marker for vascular dementia and Alzheimer's disease
    Enzo Emanuele
    Molecular Medicine Laboratory, University of Pavia, Pavia, Italy
    Int J Mol Med 13:849-53. 2004
    ..These results further support the hypothesis that vascular factors may not only play a role in the pathogenesis of VaD but also in the pathogenesis of AD...
  51. ncbi Lipoprotein(a)-associated atherothrombotic risk in hemodialysis patients
    Enzo Emanuele
    Molecular Medicine Laboratory, IRCCS San Matteo Hospital, University of Pavia, Pavia, Italy
    Am J Nephrol 24:221-9. 2004
    ..We investigated both lipoprotein(a) [Lp(a)] plasma levels and apolipoprotein(a) [apo(a)] phenotypes in relation to occurrence of atherothrombotic events in hemodialysis patients compared with subjects showing a normal kidney function...
  52. ncbi Development of the "Playing-in-Touch" (PiT) questionnaire: a measure of musical intouchness in people with low-functioning autism
    Pierluigi Politi
    Department of Health Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Neuro Endocrinol Lett 33:552-8. 2012
    ..There is accumulating evidence that people with autism have a particular affinity with music...
  53. ncbi Relationship between the -374T/A RAGE gene polymorphism and angiographic coronary artery disease
    Colomba Falcone
    Department of Cardiology, IRCCS San Matteo Hospital, University of Pavia, I 27100 Pavia, Italy
    Int J Mol Med 14:1061-4. 2004
    ..Future pathophysiological studies may be worthwhile to clarify the mechanisms behind this association...
  54. ncbi The apolipoprotein(a) component of lipoprotein(a) mediates binding to laminin: contribution to selective retention of lipoprotein(a) in atherosclerotic lesions
    Angela D'Angelo
    Molecular Medicine Laboratory, University of Pavia, IRCCS Policlinico San Matteo, Piazzale Golgi 2, Pavia, Italy
    Biochim Biophys Acta 1687:1-10. 2005
    ..In summary, our data suggest that laminin may bind to apo(a) in the atherosclerotic intima, thus contributing to the selective retention of Lp(a) in this milieu...
  55. pmc A Systematic Review and Meta-Analysis of Ginkgo biloba in Neuropsychiatric Disorders: From Ancient Tradition to Modern-Day Medicine
    Natascia Brondino
    Department of Brain and Behavioral Sciences, Section of Psychiatry, University of Pavia, via Bassi 21, 27100 Pavia, Italy
    Evid Based Complement Alternat Med 2013:915691. 2013
    ..e., autism, depression, anxiety, attention-deficit hyperactivity disorder, and addiction). Our data support the use of Gb in patients with dementia and as an adjunctive therapy in schizophrenic patients...
  56. ncbi Increased plasma aldosterone in patients with clinical depression
    Enzo Emanuele
    Molecular Medicine Laboratory, University of Pavia, Italy
    Arch Med Res 36:544-8. 2005
    ..The present study was designed, therefore, to be a cross-sectional investigation of plasma renin and aldosterone levels in depressed patients as compared with healthy controls with no history of psychiatric illness...
  57. ncbi Absence of Kir6.1/KCNJ8 mutations in Italian patients with abnormal coronary vasomotion
    Enzo Emanuele
    Molecular Medicine Laboratory, IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi 2, 27100 Pavia, Italy
    Int J Mol Med 12:509-12. 2003
    ..1/KCNJ8 gene are required to assess its role in the pathogenesis of impaired coronary vasomotility among various ethnic groups...
  58. doi Increased proapoptotic serum activity in patients with chronic mood disorders
    Pierluigi Politi
    Department of Applied Health and Behavioural Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Arch Med Res 39:242-5. 2008
    ..In this study, we sought to determine whether serum of patients with chronic mood disorders could directly induce apoptosis in human endothelial cells...
  59. doi Behavioral effects of omega-3 fatty acid supplementation in young adults with severe autism: an open label study
    Pierluigi Politi
    Department of Health Applied Sciences, Section of Psychiatry, University of Pavia, Pavia, Italy
    Arch Med Res 39:682-5. 2008
    ..However, data on the potential benefits of omega-3 supplements in young adults with severe autism are lacking. In the present study, we sought to explore this issue in an open label study...
  60. ncbi Aggressive dogs are characterized by low omega-3 polyunsaturated fatty acid status
    Simona Re
    Department of Animal Biology, University of Pavia, Pavia, Italy
    Vet Res Commun 32:225-30. 2008
    ..Whether omega-3 fatty acids supplementation may be useful to reduce aggressive behaviour in the dog deserves further investigation...
  61. pmc Anti-inflammatory effects of a topical preparation containing nicotinamide, retinol, and 7-dehydrocholesterol in patients with acne: a gene expression study
    Enzo Emanuele
    Department of Health Sciences, University of Pavia, Pavia, Italy
    Clin Cosmet Investig Dermatol 5:33-7. 2012
    ....
  62. doi Comparison of three methods for genotyping of prothrombotic polymorphisms
    Marika Bianchi
    Laboratory of Neurogenetics, IRCCS Neurological Institute C Mondino, Via Mondino 2, 27100, Pavia, Italy
    Clin Exp Med 10:269-72. 2010
    ..FRET analysis displayed higher resolution than RFLPs. Additionally, FRET analysis was faster and less tedious than sequencing...
  63. ncbi A novel mechanism of action of atorvastatin against cardiovascular risk: a commentary on "decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins"
    Enzo Emanuele
    Interdepartmental Center for Research in Molecular Medicine, University of Pavia, Viale Taramelli 24, I 27100 Pavia, Italy
    Free Radic Biol Med 43:1231-2. 2007
  64. doi Effect of electrospun fiber diameter and alignment on macrophage activation and secretion of proinflammatory cytokines and chemokines
    Enrica Saino
    Department of Biochemistry, University of Pavia, Pavia, Italy
    Biomacromolecules 12:1900-11. 2011
    ..In summary, our results indicate that the diameter of electrospun PLLA fibers, rather than fiber alignment, plays a relevant role in influencing in vitro macrophage activation and secretion of proinflammatory molecules...
  65. doi The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma2 gene is associated with plasma levels of soluble RAGE (Receptor for Advanced Glycation Endproducts) and the presence of peripheral arterial disease
    Mariella Catalano
    Research Centre on Vascular Diseases, VAS, University of Milan, Luigi Sacco Hospital, Milan, Italy
    Clin Biochem 41:981-5. 2008
    ..The aim of the present study was to clarify whether the Pro12Ala polymorphism of the PPAR-gamma2 gene is related to plasma sRAGE levels and the presence of PAD in nondiabetic Italian individuals...
  66. doi Of love and death: the emerging role of romantic disruption in suicidal behavior
    Enzo Emanuele
    Suicide Life Threat Behav 38:482. 2008
  67. ncbi Endogenous secretory RAGE as a potential biochemical screening tool for erectile dysfunction
    Enzo Emanuele
    Med Hypotheses 67:668-9. 2006
  68. ncbi The gene I love: can romanticism be hidden in a microsatellite polymorphism?
    Enzo Emanuele
    Med Hypotheses 66:867-8. 2006
  69. ncbi Caution on the potential usefulness of statins in neuropsychiatric diseases
    Natascia Brondino
    Med Hypotheses 69:697. 2007
  70. ncbi Prognostic significance of plasma osteopontin levels in patients with chronic stable angina
    Piercarlo Minoretti
    Department of Cardiology, Alessandro Manzoni Hospital of Lecco, Italy
    Eur Heart J 27:802-7. 2006
    ..The present study assessed the relationship between plasma OPN concentrations and prognosis in patients with chronic stable angina (CSA)...
  71. ncbi Brain-derived neurotrophic factor and the metabolic syndrome: more than just a hypothesis
    Diego Geroldi
    Med Hypotheses 67:195-6. 2006
  72. ncbi The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease
    Mariella Catalano
    Research Centre on Vascular Diseases, University of Milan, Luigi Sacco Hospital, Milan, Italy
    Clin Chim Acta 387:109-12. 2008
    ..The C93T polymorphism is a naturally occurring variant of the LPA gene that may influence Lp(a) concentration. The role of Lp(a) in the pathogenesis of peripheral arterial disease (PAD) has not been firmly established...
  73. ncbi Potential usefulness of sevelamer hydrochloride to improve cardiac outcome in patients with coronary disease and normal renal function
    Clara Di Vito
    Med Hypotheses 68:1182-3. 2007
  74. ncbi Atopic dermatitis and anxiety: possible role of brain-derived neurotrophic factor (BDNF)
    Serena Cremona
    Med Hypotheses 68:1419. 2007
  75. ncbi Weibel-Palade bodies exocytosis from endothelial cells: a possible mechanism mediating estrogen-related thromboembolism
    Marco Bertona
    Med Hypotheses 67:192-3. 2006