Francesco Dentali

Summary

Country: Italy

Publications

  1. ncbi request reprint Selecting patients for home treatment of deep vein thrombosis: the problem of cancer
    Walter Ageno
    Department of Internal Medicine University of Insubria, Varese, Italy
    Haematologica 87:286-91. 2002
  2. doi request reprint Relationship between ABO blood group and hemorrhage: a systematic literature review and meta-analysis
    Francesco Dentali
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 39:72-82. 2013
  3. doi request reprint Low-dose aspirin for in vitro fertilization or intracytoplasmic sperm injection: a systematic review and a meta-analysis of the literature
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 10:2075-85. 2012
  4. doi request reprint Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature
    Francesco Dentali
    Department of Clinical and Experimental Medicine, Insubria University, Varese, Italy
    Circulation 126:2381-91. 2012
  5. doi request reprint Long-term outcomes of patients with cerebral vein thrombosis: a multicenter study
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 10:1297-302. 2012
  6. doi request reprint D-dimer testing in the diagnosis of cerebral vein thrombosis: a systematic review and a meta-analysis of the literature
    F Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    J Thromb Haemost 10:582-9. 2012
  7. doi request reprint Incidence of thromboembolic complications in patients with atrial fibrillation or mechanical heart valves with a subtherapeutic international normalized ratio: a prospective multicenter cohort study
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Am J Hematol 87:384-7. 2012
  8. doi request reprint Prevalence of arterial and venous thromboembolic events in diabetic patients with and without the metabolic syndrome: a cross sectional study
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Res 127:299-302. 2011
  9. doi request reprint Thalassemia trait and arterial thromboembolic events: a systematic review and a meta-analysis of the literature
    F Dentali
    Research Center on Thromboembolic Disorders and on Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 9:917-21. 2011
  10. doi request reprint Safety of thrombolysis in cerebral venous thrombosis. A systematic review of the literature
    Francesco Dentali
    Internal Medicine, Department of Clinical Medicine, University of Insubria Ospedale di Circolo, Varese, Italy
    Thromb Haemost 104:1055-62. 2010

Detail Information

Publications87

  1. ncbi request reprint Selecting patients for home treatment of deep vein thrombosis: the problem of cancer
    Walter Ageno
    Department of Internal Medicine University of Insubria, Varese, Italy
    Haematologica 87:286-91. 2002
    ..Cancer is frequently associated with venous thromboembolism and is often considered an exclusion criterion for outpatient treatment. We investigated the impact of cancer on the outpatient management of venous thrombosis...
  2. doi request reprint Relationship between ABO blood group and hemorrhage: a systematic literature review and meta-analysis
    Francesco Dentali
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 39:72-82. 2013
    ..High-quality prospective studies are warranted to confirm these preliminary findings...
  3. doi request reprint Low-dose aspirin for in vitro fertilization or intracytoplasmic sperm injection: a systematic review and a meta-analysis of the literature
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 10:2075-85. 2012
    ..We therefore conducted a systematic review and meta-analysis of the literature investigating the effect of low-dose aspirin on hard outcomes, including live birth rate, pregnancy rate and miscarriage...
  4. doi request reprint Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature
    Francesco Dentali
    Department of Clinical and Experimental Medicine, Insubria University, Varese, Italy
    Circulation 126:2381-91. 2012
    ..Individually, NOACs were at least noninferior to vitamin K antagonists, but a clear superiority in overall and vascular mortality was not consistently proven...
  5. doi request reprint Long-term outcomes of patients with cerebral vein thrombosis: a multicenter study
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 10:1297-302. 2012
    ..Little information is available on the long-term clinical outcome of cerebral vein thrombosis (CVT)...
  6. doi request reprint D-dimer testing in the diagnosis of cerebral vein thrombosis: a systematic review and a meta-analysis of the literature
    F Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    J Thromb Haemost 10:582-9. 2012
    ..Whether D-dimer can play a similar role in the diagnostic approach to patients with suspected cerebral vein thrombosis (CVT) remains controversial...
  7. doi request reprint Incidence of thromboembolic complications in patients with atrial fibrillation or mechanical heart valves with a subtherapeutic international normalized ratio: a prospective multicenter cohort study
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Am J Hematol 87:384-7. 2012
    ..Given the frequent observation of subtherapeutic INR levels when monitoring vitamin K antagonists, this finding warrants additional investigation to improve the management of these patients...
  8. doi request reprint Prevalence of arterial and venous thromboembolic events in diabetic patients with and without the metabolic syndrome: a cross sectional study
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Res 127:299-302. 2011
    ..The presence of MS was shown to further increase the risk of arterial cardiovascular diseases (CVD) in diabetic patients. Conversely, there are no studies that have compared the risk of VTE in diabetic patients with and without the MS...
  9. doi request reprint Thalassemia trait and arterial thromboembolic events: a systematic review and a meta-analysis of the literature
    F Dentali
    Research Center on Thromboembolic Disorders and on Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 9:917-21. 2011
    ..The association between β-thalassemia trait and atherothrombotic cardiovascular events is not well established...
  10. doi request reprint Safety of thrombolysis in cerebral venous thrombosis. A systematic review of the literature
    Francesco Dentali
    Internal Medicine, Department of Clinical Medicine, University of Insubria Ospedale di Circolo, Varese, Italy
    Thromb Haemost 104:1055-62. 2010
    ..Future studies are necessary to evaluate the safety of thrombolysis in comparison to more conservative strategies...
  11. doi request reprint Brand name versus generic warfarin: a systematic review of the literature
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Pharmacotherapy 31:386-93. 2011
    ..However, closer monitoring may be reasonable when switching brands, as variations in individual INR response may be seen...
  12. doi request reprint Prevalence and clinical history of incidental, asymptomatic pulmonary embolism: a meta-analysis
    F Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Thromb Res 125:518-22. 2010
    ..Natural history of incidental PE remains unclear...
  13. doi request reprint Incidence of chronic pulmonary hypertension in patients with previous pulmonary embolism
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Thromb Res 124:256-8. 2009
    ..We therefore carried out a prospective cohort study to assess the incidence of CTPH diagnosed with echocardiography Doppler in consecutive patients with a first episode of PE...
  14. doi request reprint Natural history of mesenteric venous thrombosis in patients treated with vitamin K antagonists: a multi-centre, retrospective cohort study
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese 21100, Italy
    Thromb Haemost 102:501-4. 2009
    ..3% of patients were alive at one year, and seven patients (9.1%) died during follow up. In conclusion, patients with MTV seem to have a low risk of recurrent VTE while receiving OAT. This risk appears increased after treatment is stopped...
  15. ncbi request reprint Association between inherited thrombophilic abnormalities and central venous catheter thrombosis in patients with cancer: a meta-analysis
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 6:70-5. 2008
    ..However, information on the association between these thrombophilic abnormalities and CVC-related thrombosis are scarce...
  16. doi request reprint Brain natriuretic peptide as a preclinical marker of chronic pulmonary hypertension in patients with pulmonary embolism
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 4:123-8. 2009
    ..5-99.9). In conclusion, Nt-proBNP correlates with PAPs and may be used to exclude preclinical or symptomatic CTPH in patients with previous PE. Prospective studies on a larger population are warranted to confirm our preliminary findings...
  17. doi request reprint Prevalence of renal failure and use of antithrombotic prophylaxis among medical inpatients at increased risk of venous thromboembolic events
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Thromb Res 123:67-71. 2008
    ..We aimed to assess the prevalence of RF among medical inpatients at increased risk of VTE and the use and dosage of antithrombotic prophylaxis in these patients...
  18. doi request reprint Incidence of venous thromboembolism in patients undergoing thoracotomy for lung cancer
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    J Thorac Cardiovasc Surg 135:705-6. 2008
  19. doi request reprint Inherited thrombophilic abnormalities and risk of portal vein thrombosis. a meta-analysis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Viale Borri 57, Varese, 21100, Italy
    Thromb Haemost 99:675-82. 2008
    ..The pooled OR for PVT was 1.90 (95%CI: 1.25, 2.90) in patients with FVL and 4.48 (95%CI: 3.10, 6.48) in patients with PTM. In conclusion, PVT is associated with the presence of FVL and PTM in Western Europe...
  20. doi request reprint Polymorphisms of the Z protein protease inhibitor and risk of venous thromboembolism: a meta-analysis
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Br J Haematol 143:284-7. 2008
    ..Five studies involving 5000 patients were included. R67X and W303X mutations of Serpina10 were not associated with increased VTE risk (OR 1.63; 95% CI 0.84, 3.16 and OR 1.21; 95% CI 0.29, 4.98 respectively)...
  21. doi request reprint Incidence of thromboembolic complications in patients with mechanical heart valves with a subtherapeutic international normalized ratio
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thorac Cardiovasc Surg 137:91-3. 2009
    ..There are no data on thromboembolic event risk for these patients...
  22. doi request reprint Use of statins and recurrence of atrial fibrillation after catheter ablation or electrical cardioversion. A systematic review and meta-analysis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 106:363-70. 2011
    ..20). In conclusion, statins may lower the risk of AF recurrence after electrical cardioversion, but not ablation. However, this finding should be considered with caution, and larger RCTs are warranted to confirm our preliminary results...
  23. doi request reprint Seasonal and monthly variability in the incidence of venous thromboembolism. A systematic review and a meta-analysis of the literature
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 106:439-47. 2011
    ..Future studies are needed to better clarify the mechanisms behind this pattern...
  24. doi request reprint Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis
    Francesco Dentali
    University of Insubria, Varese, Italy
    Thromb Haemost 106:429-38. 2011
    ..9-16.6). In conclusion, our results suggest there is a low but quantifiable risk of thromboembolism in VKA-treated patients receiving PCCs for anticoagulation reversal. These findings should be confirmed in randomised, controlled trials...
  25. doi request reprint JAK2V617F mutation for the early diagnosis of Ph- myeloproliferative neoplasms in patients with venous thromboembolism: a meta-analysis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Blood 113:5617-23. 2009
    ..JAK2 mutation is strongly associated with SVT, and routine screening of JAK2 mutation appears to be indicated in these patients...
  26. ncbi request reprint The initial phase of oral anticoagulation with warfarin in outpatients with deep venous thrombosis
    Walter Ageno
    Department of Internal Medicine, University of Insubria, Varese, Italy
    Blood Coagul Fibrinolysis 14:11-4. 2003
    ..039). Patients younger than 60 years old had an odds ratio for an extended treatment of 4.92 (P = 0.0057). Algorithms with different loading doses of warfarin according to age should be proposed for outpatient treatment of DVT...
  27. ncbi request reprint Weight gain after acute deep venous thrombosis: a prospective observational study
    Walter Ageno
    Department of Internal Medicine, Ospedale di Circolo, University of Insubria, Viale Borri 57, 21100 Varese, Italy
    Thromb Res 109:31-5. 2003
    ..Weight gain is strongly associated with an increase in metabolic and cardiovascular risk factors. The aim of this study was to assess weight changes occurring after an episode of acute deep venous thrombosis (DVT)...
  28. doi request reprint The negative predictive value of D-dimer on the risk of recurrent venous thromboembolism in patients with multiple previous events: a prospective cohort study (the PROLONG PLUS study)
    Walter Ageno
    Dipartimento di Medicina Clinica, Universita dell Insubria, Varese, Italy
    Am J Hematol 87:713-5. 2012
    ..These preliminary findings suggest that negative D-dimer may identify patients with history of previous VTE at low risk of recurrences, but this approach should be tested in larger trials in highly selected patients...
  29. ncbi request reprint Residual venous obstruction in patients with a single episode of deep vein thrombosis and in patients with recurrent deep vein thrombosis
    Matteo Galli
    U O Medicina I, Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Thromb Haemost 94:93-5. 2005
    ..00001). The prevalence of RVO is significantly higher in patients with recurrent DVT than in patients with a single episode. This finding supports the importance of RVO as a potential marker of a persistent prothrombotic state...
  30. ncbi request reprint Body mass index is associated with the development of the post-thrombotic syndrome
    Walter Ageno
    Department of Internal Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 89:305-9. 2003
    ..918 and p = 0.775, respectively). BMI is significantly correlated with the development of PTS. Patients with DVT should be encouraged to avoid weight gain. Reducing patient weight might be an important strategy to prevent PTS...
  31. doi request reprint Splanchnic vein thrombosis: new risk factors and management
    Marco P Donadini
    Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese, Italy
    Thromb Res 129:S93-6. 2012
    ..High quality evidence on the acute and long-term management is substantially lacking, thus requiring further research on SVT...
  32. doi request reprint Neutrophils and clinical outcomes in patients with acute coronary syndromes and/or cardiac revascularisation. A systematic review on more than 34,000 subjects
    Luigina Guasti
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 106:591-9. 2011
    ..The findings of our systematic review highlight the potential application of this inexpensive and readily available inflammatory marker for risk stratification in patients with ACS and/or cardiac revascularisation...
  33. doi request reprint Diagnosis and management of venous thromboembolism: Results of a survey on current clinical practice
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Res 125:134-6. 2010
    ..We developed a standardized questionnaire to explore clinical practice patterns in the management of VTE, in particular about the use of pre-clinical probability and D-dimer testing and on the home treatment of pulmonary embolism (PE)...
  34. ncbi request reprint Thrombosis prophylaxis in medical patients: a retrospective review of clinical practice patterns
    Walter Ageno
    Department of Internal Medicine, University of Insubria, Italy
    Haematologica 87:746-50; discussion 250. 2002
    ..The risk of venous thromboembolism in medical patients is comparable to the risk in general surgical patients. Thromboprophylaxis is recommended for specific medical patients, but its use in clinical practice is unknown...
  35. doi request reprint Evaluation of right ventricular function in patients with a previous episode of pulmonary embolism using tissue Doppler imaging
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 8:689-94. 2013
    ..002). A high proportion of patients with previous PE have echocardiographic signs of RV diastolic dysfunction 6 months after the acute phase, even in the absence of symptoms, and in the presence of normal pulmonary pressures...
  36. doi request reprint Clinical approach to splanchnic vein thrombosis: risk factors and treatment
    Nicoletta Riva
    Research Center on Thromboembolic Diseases and Antithrombotic Therapies, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Thromb Res 130:S1-3. 2012
    ..High quality evidence on the acute and long-term management is substantially lacking and the risk to benefit-ratio of anticoagulant therapy in SVT still needs to be better assessed...
  37. ncbi request reprint Home-treatment of deep vein thrombosis in patients with cancer
    Walter Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Haematologica 90:220-4. 2005
    ..We performed a retrospective review of clinical practice patterns to assess the rate of cancer patients who were deemed eligible for outpatient treatment of their DVT...
  38. doi request reprint The new oral anticoagulants, do they change the benefit vs. risk for thromboprophylaxis in association to ambulatory surgery?
    Alessandro Squizzato
    Research Center on Thromboembolic Disorders and on Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy
    Curr Opin Anaesthesiol 23:722-5. 2010
    ..Two new drug classes, the direct thrombin and factor Xa (FXa) inhibitors, have been developed with a potentially better risk-benefit profile...
  39. doi request reprint Non-O blood type is the commonest genetic risk factor for VTE: results from a meta-analysis of the literature
    Francesco Dentali
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 38:535-48. 2012
    ..88, 95% CI, 1.42, 2.50). In conclusion, considering its prevalence, non-O blood group is a candidate to be one of the most important genetic risk factors for venous thrombosis...
  40. ncbi request reprint An unusual case of cerebral vein thrombosis in a patient with giant cell arteritis
    Marco Donadini
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 100:513-4. 2008
  41. doi request reprint The metabolic syndrome as a risk factor for venous and arterial thrombosis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 35:451-7. 2009
    ..A few recent studies suggest that the metabolic syndrome may also play a role in the pathogenesis of venous thromboembolism, but this latter finding needs confirmation by large clinical studies...
  42. ncbi request reprint Prevention of in-hospital VTE: why can't we do better?
    Walter Ageno
    Department of Clinical Medicine, University of Insubria, 21100 Varese, Italy
    Lancet 371:361-2. 2008
  43. doi request reprint Treatment options for deep vein thrombosis
    Alessandro Squizzato
    University of Insubria, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical Medicine, U O Medicina I Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Expert Opin Pharmacother 11:1069-75. 2010
    ..More recently, we have been experiencing a rapidly changing situation thanks to the development of new orally active anticoagulants...
  44. ncbi request reprint Management of coumarin-associated coagulopathy in the non-bleeding patient: a systematic review
    Francesco Dentali
    Internal Medicine, University of Insubria, Varese, Italy
    Haematologica 89:857-62. 2004
    ..Since this latter treatment can produce rapid reductions in the INR, it must be carefully tailored to meet individual needs, balancing the risk of bleeding against the potential risk of causing thromboembolism...
  45. doi request reprint Patient selection for thromboprophylaxis in medical inpatients
    Silvia Bozzato
    Department of Clinical and Experimental Medicine, Research Center on Thromboembolic Diseases and Antithrombotic Therapies, University of Insubria, Varese, Italy
    Expert Rev Cardiovasc Ther 11:1639-47. 2013
    ..In the present review, we will summarize the most recent evidence on this topic...
  46. doi request reprint Venous and arterial thrombosis associated with HIV infection
    Francesco Dentali
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 38:524-9. 2012
    ..Thus, systematic identification and aggressive treatment of traditional risk factors seem to be necessary to prevent the development of cardiovascular disease in this population...
  47. doi request reprint New direct thrombin inhibitors
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 4:479-84. 2009
    ..However, only reports from clinical practice patterns over the next months and years will tell us how and when to use the new DTIs...
  48. doi request reprint Novel risk factors for venous thromboembolism
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, UO Medicina I, Ospedale di Circolo, Varese, Italy
    Hematol Oncol Clin North Am 24:709-16, viii. 2010
    ..In this article, the authors focus on the most promising, persistent, and potentially treatable novel risk factors...
  49. ncbi request reprint Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review
    Monica Gianni
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Eur Heart J 27:1523-9. 2006
    ..To clarify the major features of the apical ballooning syndrome, we performed a systematic review of the existing literature...
  50. doi request reprint Cerebral vein thrombosis
    Francesco Dentali
    Department of Clinical Medicine, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese, Italy
    Intern Emerg Med 5:27-32. 2010
    ....
  51. ncbi request reprint Venous and arterial thrombosis in patients with HIV infection
    Evy Micieli
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Blood Coagul Fibrinolysis 18:259-63. 2007
    ..Whether this increased risk has been provoked by HIV infection itself or by other associated risk factors for cardiovascular events, such as cigarette smoking and hypertriglyceridemia, remain to be clarified...
  52. doi request reprint ABO blood group and vascular disease: an update
    Francesco Dentali
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 40:49-59. 2014
    ..28, 95% CI: 0.94-1.74). In conclusion, the results of our meta-analysis confirm the existing literature evidence of a weak association between non-O blood group and vascular arterial thrombosis, in particular myocardial ischemia...
  53. doi request reprint Plasma levels of matrix metalloproteinases and their inhibitors in hypertension: a systematic review and meta-analysis
    Chiara Marchesi
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Hypertens 30:3-16. 2012
    ..The aim of this meta-analysis is to elucidate the behavior of plasma MMP and TIMP levels in hypertension and their relationship to cardiovascular remodeling...
  54. doi request reprint Statins, fibrates, and venous thromboembolism: a meta-analysis
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Eur Heart J 31:1248-56. 2010
    ..The aim is to make a systematic review of the literature to assess the effect of lipid-lowering drugs on venous thromboembolism (VTE) occurrence...
  55. ncbi request reprint Natural history of cerebral vein thrombosis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Curr Opin Pulm Med 13:372-6. 2007
    ....
  56. doi request reprint Seasonal variability of venous thromboembolism
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Curr Opin Pulm Med 15:403-7. 2009
    ..This review will briefly summarize current evidence in this area...
  57. doi request reprint Traditional and non traditional risk factors in accelerated atherosclerosis in systemic lupus erythematosus: role of vascular endothelial growth factor (VEGATS Study)
    Barbara Maria Colombo
    Department of Internal Medicine, University of Genoa, Italy
    Autoimmun Rev 8:309-15. 2009
    ..To evaluate the role of vascular endothelial growth factor (VEGF) in accelerated atherosclerosis in patients with Systemic Lupus Erythematosus (SLE)...
  58. doi request reprint Outpatient treatment and early discharge of symptomatic pulmonary embolism: a systematic review
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Eur Respir J 33:1148-55. 2009
    ....
  59. doi request reprint Antithrombotic and fibrinolytic drugs for retinal vein occlusion: a systematic review and a call for action
    A Squizzato
    Medicina I Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Thromb Haemost 103:271-6. 2010
    ..No firm recommendation can be provided given the limited available evidence...
  60. doi request reprint Prognostic significance of residual venous obstruction in patients with treated unprovoked deep vein thrombosis: a patient-level meta-analysis
    Marco P Donadini
    Marco P Donadini, Department of Clinical and Experimental Medicine, University of Insubria, Via Guicciardini, 9, 21100 Varese, Italy, Tel 39 0332 278831, Fax 39 0332 278818, E mail
    Thromb Haemost 111:172-9. 2014
    ..e. >6 months (HR = 1.19; 95% CI: 0.87-1.61). In conclusion, after a first unprovoked DVT, RVO is a weak overall predictor of recurrent VTE. The association is stronger if RVO is detected at an earlier time (3 months) after thrombosis. ..
  61. doi request reprint Antithrombotic treatment of splanchnic vein thrombosis: results of an international registry
    Walter Ageno
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 40:99-105. 2014
    ....
  62. doi request reprint Accuracy of emergency physician-performed ultrasonography in the diagnosis of deep-vein thrombosis: a systematic review and meta-analysis
    Fulvio Pomero
    Department of Clinical Medicine, ASO S Croce e Carle, Cuneo, Italy
    Thromb Haemost 109:137-45. 2013
    ..6-98.5%), and with a weighted mean specificity of 96.8% (95%CI:94.6-98.1%). Our findings suggest that EPPU may be useful in the management of patients with suspected DVT. Future prospective studies are warranted to confirm these findings...
  63. doi request reprint 5 flourouracil-induced apical ballooning syndrome: a case report
    Monica Gianni
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Blood Coagul Fibrinolysis 20:306-8. 2009
    ..In our patient, both supraphysiologic levels of plasma catecholamines and stress related neuropeptides caused by cancer diagnosis as well as chemotherapy may have contributed the development of ABS...
  64. ncbi request reprint Acquired thrombophilia during pregnancy
    Francesco Dentali
    Department of Medicine, Insubria University, Viale Borri 57, Varese, Italy 21100
    Obstet Gynecol Clin North Am 33:375-88. 2006
    ..Other forms of acquired thrombophilia are uncommon or of unknown clinical significance. Treatments aimed at mitigating the impacts of these states lack clear evidence to support their use...
  65. ncbi request reprint Retrievable vena cava filters: clinical experience
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Curr Opin Pulm Med 12:304-9. 2006
    ..To summarize currently available literature regarding indications for inferior vena cava filters, potential problems associated with the different filters available, and the efficacy and safety of retrievable inferior vena cava filters...
  66. pmc Angiotensin II type 1 and type 2 receptor expression in circulating monocytes of diabetic and hypercholesterolemic patients over 3-month rosuvastatin treatment
    Franca Marino
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Cardiovasc Diabetol 11:153. 2012
    ..We sought to investigate the potential changes of AT1R-AT2R expression in human monocytes of type 2 diabetic- hypercholesterolemic patients and in hypercholesterolemic subjects, upon clinical treatment with rosuvastatin...
  67. doi request reprint Venous ischemic syndromes
    Walter Ageno
    Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Front Neurol Neurosci 30:191-4. 2012
    ..Coma, epileptic seizures and intracranial hemorrhage were shown, among others, to be independent predictors of poor outcome...
  68. ncbi request reprint Prophylaxis of venous thromboembolism following laparoscopic surgery: where is the evidence?
    W Ageno
    University of Insubria, Internal Medicine, Varese, Italy
    J Thromb Haemost 3:214-5. 2005
  69. ncbi request reprint Atrial fibrillation and antithrombotic treatment in Italian hospitalized patients: a prospective, observational study
    W Ageno
    Department of Clinical and Biological Sciences, University of Insubria, Ospedale di Circolo di Varese, Viale Borri 57, 21100 Varese, Italy
    J Thromb Thrombolysis 12:225-30. 2001
    ..We studied the prevalence of atrial fibrillation within a large Italian inpatient population, and evaluated the use of antithrombotic therapy among these individuals...
  70. ncbi request reprint Venous thromboembolism and arterial thromboembolism. Many similarities, far beyond thrombosis per se
    Walter Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 100:181-3. 2008
  71. ncbi request reprint The metabolic syndrome and the risk of venous thrombosis: a case-control study
    W Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 4:1914-8. 2006
    ..The metabolic syndrome is a cluster of risk factors for atherosclerosis. Its impact on VTE is unknown...
  72. ncbi request reprint A survey of thrombosis prophylaxis use in patients undergoing arthroscopic surgery
    W Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 2:1901-2. 2004
  73. ncbi request reprint Low dose oral vitamin K to reverse acenocoumarol-induced coagulopathy: a randomized controlled trial
    W Ageno
    Department of Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 88:48-51. 2002
    ..5 to 10.0. Furthermore, the use of a 1 mg dose of oral vitamin K results in an excessive risk of over-reversal of the INR...
  74. ncbi request reprint Predictors of residual venous obstruction after deep vein thrombosis of the lower limbs: a prospective cohort study
    W Ageno
    Department of Internal Medicine, Ospedale di Circolo, University of Insubria, Varese, Italy
    Thromb Res 108:203-7. 2002
    ..Predictors of residual venous occlusion are unknown. We hypothesized that obesity, which causes reduced fibrinolytic activity, can predict delayed thrombus regression...
  75. ncbi request reprint The incidence of venous thromboembolism following gynecologic laparoscopy: a multicenter, prospective cohort study
    W Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 5:503-6. 2007
    ..Gynecologic laparoscopy is a common procedure, and is frequently performed in low-risk patients. To our knowledge, there are no clinical studies specifically designed to assess the incidence of VTE in this setting...
  76. ncbi request reprint Upper extremity deep vein thrombosis and pulmonary embolism after coronary bypass surgery: a case report and preliminary results from a prospective study evaluating patients during cardiac rehabilitation
    Marco Ambrosetti
    Division of Cardiology, IRCCS S Maugeri Foundation, Tradate VA, Italy
    Ital Heart J 5:241-4. 2004
    ..Catheter-related UEDVT and pulmonary embolism may complicate coronary bypass surgery and should be taken into consideration when managing patients after surgery...
  77. ncbi request reprint Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients
    Francesco Dentali
    McMaster University and St Joseph s Healthcare, Hamilton, Ontario, Canada
    Ann Intern Med 146:278-88. 2007
    ..Underutilization of anticoagulant prophylaxis may be due to lack of evidence that prophylaxis prevents clinically important outcomes in hospitalized medical patients at risk for venous thromboembolism...
  78. ncbi request reprint Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: a meta-analysis
    Francesco Dentali
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Blood 107:2766-73. 2006
    ..07; 95% CI 2.54 to 6.52; P < .001). We concluded that OC users, and patients with factor V Leiden, the prothrombin G20 120A mutation, and hyperhomocysteinemia are at a significantly increased risk of CVT...
  79. ncbi request reprint The metabolic syndrome and the risk of thrombosis
    Francesco Dentali
    Haematologica 92:297-9. 2007
  80. ncbi request reprint Metabolic syndrome and hyperhomocysteinemia in patients with deep vein thrombosis: a case-control study
    Francesco Dentali
    Haematologica 92:1293-4. 2007
    ..However, only the presence of MS was independently associated with DVT, and the coexistence of both risk factors did not increase the magnitude of the association...
  81. ncbi request reprint Venous thrombosis at unusual sites and the role of thrombophilia
    Federico Lussana
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Semin Thromb Hemost 33:582-7. 2007
    ..The understanding of these mechanisms might facilitate diagnosis with appropriate investigations and improve therapeutic decision making...
  82. ncbi request reprint Meta-analysis: low-molecular-weight heparin and bleeding in patients with severe renal insufficiency
    Wendy Lim
    McMaster University and Hamilton General Hospital, Hamilton, Ontario, Canada
    Ann Intern Med 144:673-84. 2006
    ....
  83. ncbi request reprint Combined aspirin-oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease: a meta-analysis of randomized trials
    Francesco Dentali
    Department of Medicine, McMaster University, and St Joseph s Healthcare, Hamilton, Ontario, Canada
    Arch Intern Med 167:117-24. 2007
    ..We performed a systematic review and meta-analysis of randomized controlled trials comparing these 2 treatment strategies (combined aspirin-OAC therapy vs OAC therapy alone) to assess the therapeutic benefits and risks...
  84. ncbi request reprint Tailoring warfarin induction doses to reflect individual and disease-specific factors
    Walter Ageno
    Am J Med 118:143-4. 2005
  85. ncbi request reprint Does celecoxib potentiate the anticoagulant effect of warfarin? A randomized, double-blind, controlled trial
    Francesco Dentali
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Ann Pharmacother 40:1241-7. 2006
    ..Cyclooxygenase-2 selective NSAIDs such as celecoxib may be less likely to promote gastrointestinal bleeding; however, there are concerns that they could potentiate the anticoagulation effect of warfarin...
  86. ncbi request reprint Natural history of cerebral vein thrombosis: a systematic review
    Francesco Dentali
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Blood 108:1129-34. 2006
    ..8% (range, 0%-11.7%) had objectively confirmed recurrence. We conclude that patients with CVT have a low risk of death and that most patients have a good long-term prognosis...
  87. ncbi request reprint A survey of thrombosis prophylaxis use in patients with lower limb fractures
    Walter Ageno
    Thromb Haemost 92:1166-7. 2004