V De Sanctis

Summary

Country: Italy

Publications

  1. ncbi request reprint Growth hormone and adrenal response to intramuscular glucagon test and its relationship to IGF-1 production and left ventricular ejection fraction in adult B-thalassemia major patients
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Viale Cavour, Ferrara, Italy
    Pediatr Endocrinol Rev 8:290-4. 2011
  2. pmc Growth and endocrine disorders in thalassemia: The international network on endocrine complications in thalassemia (I-CET) position statement and guidelines
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Indian J Endocrinol Metab 17:8-18. 2013
  3. ncbi request reprint Osteoporosis in thalassemia major: an update and the I-CET 2013 recommendations for surveillance and treatment
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 11:167-80. 2013
  4. ncbi request reprint Klinefelter syndrome and cancer: from childhood to adulthood
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, 44121 Ferrara, Italy
    Pediatr Endocrinol Rev 11:44-50. 2013
  5. pmc Menstrual pattern and menstrual disorders among adolescents: an update of the Italian data
    Franco Rigon
    Department of Paediatrics, University of Padua, Padua, Italy
    Ital J Pediatr 38:38. 2012
  6. ncbi request reprint Iron overload and glucose metabolism in subjects with β-thalassaemia major: an overview
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, 44121 Ferrara, Italy
    Curr Diabetes Rev 9:332-41. 2013
  7. ncbi request reprint Reproductive health in young male adults with chronic diseases in childhood
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 10:284-96. 2013
  8. doi request reprint Hypoparathyroidism: from diagnosis to treatment
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Curr Opin Endocrinol Diabetes Obes 19:435-42. 2012
  9. ncbi request reprint Varicocele in the adolescent
    Vincenzo De Sanctis
    Department of Reproduction and Growth, Pediatric and Adolescent Unit, St Anna Hospital, Corso Giovecca, 203 44100 Ferrara, Italy
    Pediatr Endocrinol Rev 5:468-70. 2007
  10. ncbi request reprint Exaggerated TSH response to TRH ("sub-biochemical" hypothyroidism) in prepubertal and adolescent thalassaemic patients with iron overload: prevalence and 20-year natural history
    Vincenzo De Sanctis
    Department of Reproduction, Paediatric and Thalassaemia Unit, St Anna Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 6:170-3. 2008

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Growth hormone and adrenal response to intramuscular glucagon test and its relationship to IGF-1 production and left ventricular ejection fraction in adult B-thalassemia major patients
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Viale Cavour, Ferrara, Italy
    Pediatr Endocrinol Rev 8:290-4. 2011
    ..According to the international guidelines for medical practice, we believe that before considering hormone replacement therapy, a second test to confirm the diagnosis of GHD and adrenal insufficiency is required...
  2. pmc Growth and endocrine disorders in thalassemia: The international network on endocrine complications in thalassemia (I-CET) position statement and guidelines
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Indian J Endocrinol Metab 17:8-18. 2013
    ..The I-CET position statement outlined in this document applies to patients with transfusion-dependent thalassemia major to help physicians to anticipate, diagnose, and manage these complications properly...
  3. ncbi request reprint Osteoporosis in thalassemia major: an update and the I-CET 2013 recommendations for surveillance and treatment
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 11:167-80. 2013
    ..The recommendations of the International Network on Growth Disorders and Endocrine Complications in Thalassaemia (I-CET) for diagnosis and management of osteoporosis in TM are also briefly included in this review...
  4. ncbi request reprint Klinefelter syndrome and cancer: from childhood to adulthood
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, 44121 Ferrara, Italy
    Pediatr Endocrinol Rev 11:44-50. 2013
    ..This review paper summarizes the current knowledge about cancer risk from childhood to adulthood in patients with KS...
  5. pmc Menstrual pattern and menstrual disorders among adolescents: an update of the Italian data
    Franco Rigon
    Department of Paediatrics, University of Padua, Padua, Italy
    Ital J Pediatr 38:38. 2012
    ..The aims of this study were to produce up-to-date information on the menstrual pattern of Italian girls attending secondary school, and to estimate the prevalence of menstrual cycle abnormalities in this population...
  6. ncbi request reprint Iron overload and glucose metabolism in subjects with β-thalassaemia major: an overview
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, 44121 Ferrara, Italy
    Curr Diabetes Rev 9:332-41. 2013
    ..Therefore the incidence of disturbed glucose homeostasis depends on adherence to chelation treatment, the adequacy of the dosage, the chemical properties of the chelating agent and the prevention of liver infections...
  7. ncbi request reprint Reproductive health in young male adults with chronic diseases in childhood
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 10:284-96. 2013
    ..Reproductive health medicine should take a wider view to create a physical, psychological and genetic wellbeing of these patients...
  8. doi request reprint Hypoparathyroidism: from diagnosis to treatment
    Vincenzo De Sanctis
    Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy
    Curr Opin Endocrinol Diabetes Obes 19:435-42. 2012
    ..This review provides an update on hypoparathyroidism (HPT), focusing on the major aspects of diagnosis, clinical manifestations and management of patients with hypocalcaemia due to HPT...
  9. ncbi request reprint Varicocele in the adolescent
    Vincenzo De Sanctis
    Department of Reproduction and Growth, Pediatric and Adolescent Unit, St Anna Hospital, Corso Giovecca, 203 44100 Ferrara, Italy
    Pediatr Endocrinol Rev 5:468-70. 2007
    ..This statement offers recommendations regarding the best practice policies for evaluation and treatment of varicocele in adolescents...
  10. ncbi request reprint Exaggerated TSH response to TRH ("sub-biochemical" hypothyroidism) in prepubertal and adolescent thalassaemic patients with iron overload: prevalence and 20-year natural history
    Vincenzo De Sanctis
    Department of Reproduction, Paediatric and Thalassaemia Unit, St Anna Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 6:170-3. 2008
    ..Our data suggest that an exaggerated TSH response to TRH test is frequent in beta-thalassemia major, and may evolve into subclinical or overt hypothyroidism as we found in 37.5% of our patients with sub-biochemical hypothyroidism...
  11. ncbi request reprint Mild subclinical hypothyroidism in thalassaemia major: prevalence, multigated radionuclide test, clinical and laboratory long-term follow-up study
    Vincenzo De Sanctis
    Department of Reproduction, Paediatric and Thalassaemia Unit, St Anna Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 6:174-80. 2008
    ..In addition, therapy with L-thyroxine should be considered in iron overloaded TM patients with SH and a poor response to chelation therapy and in patients with SH and mild iron overload...
  12. ncbi request reprint Cardiomyopathy and pericardial effusion in a 7 year-old boy with beta-thalassaemia major, severe primary hypothyroidism and hypoparathyroidism due to iron overload
    Vincenzo De Sanctis
    Department of Reproduction, Paediatric and Thalassaemia Unit, St Anna Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 6:181-4. 2008
    ..The patient was discharged from our Unit after 7 days and within 3 months he had appreciable myocardial improvement and disappearance of the pericardial effusion...
  13. ncbi request reprint Spermatozoal DNA damage in patients with B thalassaemia syndromes
    Vincenzo De Sanctis
    Department of Reproduction, Paediatric and Thalassaemia Unit, St Anna Hospital, Ferrara, Italy
    Pediatr Endocrinol Rev 6:185-9. 2008
    ..to determine whether sperm DNA damage is increased in patients with beta-thalassaemia syndromes...
  14. ncbi request reprint Severe hypercalcemia in a patient treated for hypoparathyroidism with calcitriol
    Vincenzo De Sanctis
    Department of Reproduction and Growth, Pediatric and Adolescent Unit, Arcispedale St Anna, Ferrara Italy
    Pediatr Endocrinol Rev 7:363-5. 2010
    ..He was also receiving levothyroxine for primary hypothyroidism and iron chelation therapy with desferioxamine mesylate for the severe iron overload...
  15. ncbi request reprint Fertility preservation in adolescents with Klinefelter's syndrome
    Vincenzo De Sanctis
    Department of Reproduction and Growth Pediatric and Adolescent Unit, Arcispedale St Anna, Ferrara, Italy
    Pediatr Endocrinol Rev 8:178-81. 2010
    ..These issues are addressed here with the aim of assisting physicians in the management of adolescents with KS...
  16. ncbi request reprint Abnormal seminal parameters in patients with thalassemia intermedia and low serum folate levels
    Vincenzo De Sanctis
    Quisisana Hospital, Viale Cavour 128, Ferrara, Italy
    Pediatr Endocrinol Rev 8:310-3. 2011
    ..749, p: 0.001) and total sperm concentration and serum folate (r: 0.572, p: 0.02). Despite some limitations, our study has useful clinical implications for the treatment of patients with thalassemia intermedia...
  17. ncbi request reprint Acquired central hypothyroidism in a male thalassaemic patient with severe iron overload
    Vincenzo De Sanctis
    Quisisana Hospital, Via Paolo V, 25 44121, Ferrara, Italy
    Pediatr Endocrinol Rev 8:322-3. 2011
    ..This case report stresses the importance of following thyroid function in TM patients and underlines the criteria for diagnosis and treatment...
  18. ncbi request reprint Generalized tonic-clonic seizures in a thalassemic patient with hypoparathyroidism and brain calcinosis
    Vincenzo De Sanctis
    Quisisana Hospital, Viale Cavour 128, 44121 Ferrara, Italy
    Pediatr Endocrinol Rev 8:334-6. 2011
    ..After treatment with oral calcium supplementation and calcitriol she did not experience any further seizures. In addition, we present a brief review of the literature and report the Authors' recommendations...
  19. ncbi request reprint Impact of long-term iron chelation therapy on growth and endocrine functions in thalassaemia
    Vincenzo De Sanctis
    Department of Reproduction and Growth, Paediatric and Adolescent Unit, S Anna Hospital, Ferrara, Italy
    J Pediatr Endocrinol Metab 19:471-80. 2006
    ..In conclusion, our study noted a positive effect of DFX therapy on sexual maturation and endocrine complications. Nevertheless, short stature has persisted despite major advances in treatment...
  20. ncbi request reprint Prevalence of endocrine complications and short stature in patients with thalassaemia major: a multicenter study by the Thalassaemia International Federation (TIF)
    Vincenzo De Sanctis
    Department of Reproduction and Growth, Pediatric and Adolescent Unit, Arcispedale S Anna, Ferrara, Italy
    Pediatr Endocrinol Rev 2:249-55. 2004
    ..In conclusion, since iron overload and liver damage seem to be the most important factors responsible for endocrine complications, adequate compliance to chelation therapy and rigid precautions against liver infections are imperative...
  21. ncbi request reprint Growth and puberty and its management in thalassaemia
    V De Sanctis
    Department of Growth and Reproduction, Pediatric and Adolescent Unit, Arcispedale S Anna, Ferrara, Italy
    Horm Res 58:72-9. 2002
    ..Since the quality of life of these patients is an important aim, it is vital to monitor carefully the growth and pubertal development in order to detect abnormalities and to initiate appropriate and early treatment...
  22. pmc Gonadal function in patients with beta thalassaemia major
    V De Sanctis
    Department of Paediatrics, Arcispedale S Anna, Ferrara, Italy
    J Clin Pathol 41:133-7. 1988
    ..It is important to assess hypothalamic-pituitary-gonadal function in young women with beta thalassaemia major, so that those with glandular dysfunction may be started on replacement therapy...
  23. ncbi request reprint Pubertal gynecomastia
    V De Sanctis
    Istituto di Pediatria, Universita di Ferrara, Ferrara, Italy
    Minerva Pediatr 54:357-61. 2002
  24. ncbi request reprint Hypothalamic-pituitary-gonadal axis in thalassemic patients with secondary amenorrhea
    V De Sanctis
    Department of Pediatrics, Arcispedale S Anna, Ferrara, Italy
    Obstet Gynecol 72:643-7. 1988
    ..We conclude that both pituitary and gonadal damage may be responsible for the secondary amenorrhea in thalassemic patients...
  25. pmc Gonadal function after allogenic bone marrow transplantation for thalassaemia
    V De Sanctis
    Department of Paediatrics, Arcispedale S Anna, Ferrara
    Arch Dis Child 66:517-20. 1991
    ..These findings emphasise the need for vigilant long term follow up of thalassaemic patients treated with cytotoxic chemotherapy for bone marrow transplantation so that those requiring hormone replacement can be identified and treated...
  26. ncbi request reprint Obesity in adolescents living in Mediterranean countries: the report of Mediterranean Action Group on Adolescent Medicine (MAGAM), Castriadas Cagliari, Italy, 24 October 2003
    V De Sanctis
    Pediatric and Adolescent Unit, Arcispedale S Anna, Ferrara, Italy
    Pediatr Endocrinol Rev 1:340-2. 2004
  27. ncbi request reprint Evaluation of the spermiogram in the adolescents
    V De Sanctis
    Istituto di Pediatria, Universita di Ferrara, Ferrara, Italy
    Minerva Pediatr 54:349-56. 2002
  28. ncbi request reprint Regression of autoimmunity and abnormal glucose homeostasis in an adolescent boy with silent coeliac disease
    P Banin
    Department of Growth and Reproduction, S Anna Hospital, Ferrara, Italy
    Acta Paediatr 91:1141-3. 2002
    ....
  29. ncbi request reprint Growth and puberty in thalassemia major
    G Raiola
    Auxoendocrinological Unit and Department of Pediatrics, Pugliese Ciaccio Hospital, Catanzaro, Italy
    J Pediatr Endocrinol Metab 16:259-66. 2003
    ..Both groups need hormonal replacement therapy. These data support the need for vigilant follow-up of patients with thalassemia before and after transplantation, in order to treat endocrine dysfunctions at the appropriate age...
  30. ncbi request reprint Final height in short polytransfused thalassemia major patients treated with recombinant growth hormone
    L Cavallo
    Division of Pediatrics B Trambusti, University of Bari, Policlinico, Bari, Italy
    J Endocrinol Invest 28:363-6. 2005
    ..A negative correlation was found between FH and the length of treatment (r=-0.56, p=0.004). Our data seem to exclude that prolonged rhGH therapy could improve FH in Th patients; on the contrary, a negative effect may be hypothesized...
  31. ncbi request reprint Antioxidant capacity in seminal plasma of transfusion-dependent beta-thalassemic patients
    A Carpino
    Department of Cell Biology, University of Calabria, Cosenza, Italy
    Exp Clin Endocrinol Diabetes 112:131-4. 2004
    ..Enzymatic and non enzymatic antioxidant capacities, as well as lipoperoxide content, were investigated in seminal plasma of these patients to evaluate a possible oxidative stress...
  32. ncbi request reprint Menstrual disorders in adolescence
    F Rigon
    Service of Pediatric and Adolescent Age Endocrinology, Department of Pediatrics, University of Padua, Padua, Italy
    Minerva Pediatr 58:227-46. 2006
    ..The treatment of dysmenorrhea and quantitative alterations of the menstrual cycle is the focus of this article...
  33. ncbi request reprint Characterization of pseudoxanthoma elasticum-like lesions in the skin of patients with beta-thalassemia
    M Baccarani-Contri
    Department of Biomedical Sciences, General Pathology Unit, University of Modena and Reggio Emilia, Italy
    J Am Acad Dermatol 44:33-9. 2001
    ..CONCLUSION: Data indicate that patients with beta-thalassemia may undergo important alterations of connective tissues, a better understanding of which may help in preventing clinical complications...
  34. ncbi request reprint Unresolved problems in optimal therapy of pubertal disorders in oncological and bone marrow transplanted patients
    M Bozzola
    Department of Paediatrics, IRCCS Policlinco S. Matteo, Pavia, Italy
    J Pediatr Endocrinol Metab 14:997-1002. 2001
    ..In the consensus guidelines that follow the overview an attempt is made to help optimise patients' growth and puberty by suggesting practical clinical approaches to some of the most challenging issues...
  35. ncbi request reprint Hypoparathyroidism and pseudohypoparathyroidism
    C de Sanctis
    Endocrinologia Pediatrica, Ospedale Infantile Regina Margherita, Istituti Universitari di Pediatria, Turin, Italy
    Minerva Pediatr 54:271-8. 2002
  36. ncbi request reprint Hypothyroidism
    L Tato
    Clinica Pediatrica dell Universita, Policlinico Borgo Roma, Verona, Italy
    Minerva Pediatr 54:279-85. 2002
  37. ncbi request reprint Subclinical hypothyroidism
    G Bona
    Department of Pediatrics, Novara, Italy
    Minerva Pediatr 57:195-9. 2005
  38. ncbi request reprint [Kearns-Sayre syndrome associated with growth hormone deficiency]
    V De Sanctis
    Azienda Ospedaliera Universitaria di Ferrara, Arcispedale Sant Anna, UO Divisione Pediatrica
    Pediatr Med Chir 25:447-51. 2003
    ..The patient was treated with human recombinant GH for 6 months but the growth velocity/year did not change. The Authors report a brief review of the literature on the ethiopatogenesis of GH deficiency observed in this patient is given...
  39. ncbi request reprint Delayed puberty and hypogonadism
    G Tonini
    Departments of Pediatrics of Trieste, Italy
    Minerva Pediatr 54:475-81. 2002