Marco De Santis

Summary

Country: Italy

Publications

  1. ncbi request reprint Drug-induced congenital defects: strategies to reduce the incidence
    M De Santis
    Department of Obstetrics and Gynaecology, Catholic University of Sacred Heart, Rome, Italy
    Drug Saf 24:889-901. 2001
  2. ncbi request reprint Periconceptional exposure to efavirenz and neural tube defects
    Marco De Santis
    Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
    Arch Intern Med 162:355. 2002
  3. ncbi request reprint Mesothelioma mortality surveillance and asbestos exposure tracking in Italy
    Lucia Fazzo
    Dipartimento di Ambiente e Connessa Prevenzione Primaria Istituto Superiore di Sanità, Rome, Italy
    Ann Ist Super Sanita 48:300-10. 2012
  4. doi request reprint Paternal exposure and counselling: experience of a Teratology Information Service
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynaecology, Catholic University of Sacred Heart, Rome, Italy
    Reprod Toxicol 26:42-6. 2008
  5. doi request reprint First-trimester itraconazole exposure and pregnancy outcome: a prospective cohort study of women contacting teratology information services in Italy
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
    Drug Saf 32:239-44. 2009
  6. ncbi request reprint Prenatal drug exposure and teratological risk: one-year experience of an Italian Teratology Information Service
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Med Sci Monit 14:PH1-8. 2008
  7. ncbi request reprint Antiepileptic drugs during pregnancy: pharmacokinetics and transplacental transfer
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynaecology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Curr Pharm Biotechnol 12:781-8. 2011
  8. doi request reprint Folic acid use in planned pregnancy: an Italian survey
    Marco De Santis
    Department of Obstetrics and Gynaecology, Telefono Rosso Teratology Information Service, Universita Cattolica del Sacro Cuore, L go Francesco Vito 1, 00135 Rome, Italy
    Matern Child Health J 17:661-6. 2013
  9. ncbi request reprint Is there significant improvement in neonatal outcome after treating pPROM mothers with amnio-infusion?
    Maria Pia De Carolis
    Division of Neonatology, Catholic University Sacred Heart, Rome, Italy
    Biol Neonate 86:222-9. 2004
  10. ncbi request reprint Radiation effects on development
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University, Largo Agostino Gemelli 1, Rome, Italy
    Birth Defects Res C Embryo Today 81:177-82. 2007

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Drug-induced congenital defects: strategies to reduce the incidence
    M De Santis
    Department of Obstetrics and Gynaecology, Catholic University of Sacred Heart, Rome, Italy
    Drug Saf 24:889-901. 2001
    ..g. avoidance of chemotherapy during the first trimester, avoidance of nonsteroidal anti-inflammatory drugs in the third trimester, and avoidance of high doses of benzodiazepines in the period imminent to prepartum)...
  2. ncbi request reprint Periconceptional exposure to efavirenz and neural tube defects
    Marco De Santis
    Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
    Arch Intern Med 162:355. 2002
  3. ncbi request reprint Mesothelioma mortality surveillance and asbestos exposure tracking in Italy
    Lucia Fazzo
    Dipartimento di Ambiente e Connessa Prevenzione Primaria Istituto Superiore di Sanità, Rome, Italy
    Ann Ist Super Sanita 48:300-10. 2012
    ..Previous mortality studies at national level employed the topographic code "Malignant neoplasms of pleura", because of unavailability of a specific code in ICD-9 Revision for pleural mesothelioma...
  4. doi request reprint Paternal exposure and counselling: experience of a Teratology Information Service
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynaecology, Catholic University of Sacred Heart, Rome, Italy
    Reprod Toxicol 26:42-6. 2008
    ....
  5. doi request reprint First-trimester itraconazole exposure and pregnancy outcome: a prospective cohort study of women contacting teratology information services in Italy
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
    Drug Saf 32:239-44. 2009
    ..Itraconazole is an effective fungal treatment; however, there are few human data on prenatal exposure...
  6. ncbi request reprint Prenatal drug exposure and teratological risk: one-year experience of an Italian Teratology Information Service
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Med Sci Monit 14:PH1-8. 2008
    ..The aim of this study is to present data on the most common pharmaceutical products responsible for teratogenic risk in the one-year experience of a teratology information service in Italy...
  7. ncbi request reprint Antiepileptic drugs during pregnancy: pharmacokinetics and transplacental transfer
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynaecology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Curr Pharm Biotechnol 12:781-8. 2011
    ..New AEDs seem to have a less teratogenic effect, but human experience is still limited. The purpose of this review is to provide an update on AED exposure in pregnancy, focusing on pharmacokinetics and transplacental transport...
  8. doi request reprint Folic acid use in planned pregnancy: an Italian survey
    Marco De Santis
    Department of Obstetrics and Gynaecology, Telefono Rosso Teratology Information Service, Universita Cattolica del Sacro Cuore, L go Francesco Vito 1, 00135 Rome, Italy
    Matern Child Health J 17:661-6. 2013
    ..Knowledge about the benefits of this vitamin is inadequate also among women who planned the pregnancy and the level of information received from their physicians...
  9. ncbi request reprint Is there significant improvement in neonatal outcome after treating pPROM mothers with amnio-infusion?
    Maria Pia De Carolis
    Division of Neonatology, Catholic University Sacred Heart, Rome, Italy
    Biol Neonate 86:222-9. 2004
    ..In fact, over 20 weeks, amnio-infusion treatment significantly reduces the risk of pulmonary hypoplasia even if normal lung development cannot be guaranteed...
  10. ncbi request reprint Radiation effects on development
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University, Largo Agostino Gemelli 1, Rome, Italy
    Birth Defects Res C Embryo Today 81:177-82. 2007
    ..In this review we focus on the relevance of estimating the cumulative dose of radiation to the fetus and the gestational age in which exposure occurs, to provide appropriate counseling to pregnant women...
  11. doi request reprint Sexuality, pre-conception counseling and urological management of pregnancy for young women with spina bifida
    Daniela Visconti
    Telefono Rosso, Teratology Information Service, Department of Obstetrics and Gynaecology, Sacro Cuore Catholic University, Rome, Italy
    Eur J Obstet Gynecol Reprod Biol 163:129-33. 2012
    ..Moreover, we aim to support young women with spina bifida, providing pre-conception counseling and practical guidelines essential for the urological management of their pregnancy...
  12. doi request reprint Smoke, alcohol consumption and illicit drug use in an Italian population of pregnant women
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynaecology, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, Rome, Italy
    Eur J Obstet Gynecol Reprod Biol 159:106-10. 2011
    ..The aim of this study is to describe risk behaviours in a population of Italian women calling our TIS and to identify related maternal factors...
  13. ncbi request reprint Latanoprost exposure in pregnancy
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Am J Ophthalmol 138:305-6. 2004
    ..As a consequence it is classified as category C drug according to the United States Food and Drug Administration's use-in-pregnancy ratings...
  14. ncbi request reprint Early first-trimester sibutramine exposure : pregnancy outcome and neonatal follow-up
    Marco De Santis
    Department of Obstetrics and Gynecology, Telefono Rosso Teratology Information Service, Catholic University of the Sacred Heart, Rome, Italy
    Drug Saf 29:255-9. 2006
    ..The objective of our study was to determine whether sibutramine exposure during pregnancy constitutes a risk factor to the mother and developing fetus...
  15. doi request reprint Use of the Internet by women seeking information about potentially teratogenic agents
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynaecology, Catholic University of Sacred Heart, Rome, Italy
    Eur J Obstet Gynecol Reprod Biol 151:154-7. 2010
    ....
  16. doi request reprint Pleural mesothelioma mortality and asbestos exposure mapping in Italy
    Lucia Fazzo
    Environmental Epidemiology Unit, Department of Environment and Primary Prevention, Istituto Superiore di Sanita, Rome, Italy
    Am J Ind Med 55:11-24. 2012
    ..An epidemic of asbestos-related diseases is ongoing worldwide. Mortality from malignant pleural neoplasms in Italy was analyzed, to estimate the health impact of asbestos at national and local level...
  17. ncbi request reprint Failure of the emergency contraceptive levonorgestrel and the risk of adverse effects in pregnancy and on fetal development: an observational cohort study
    Marco De Santis
    Telefono Rosso, Teratology Information Service, Department of Obstetrics and Gynaecology, Catholic University of Sacred Heart, Rome, Italy
    Fertil Steril 84:296-9. 2005
    ..To determine pregnancy and neonatal outcome after the failure of levonorgestrel as an emergency contraceptive...
  18. ncbi request reprint First case of post-conception Verteporfin exposure: pregnancy and neonatal outcome
    Marco De Santis
    Telefono Rosso, Teratology Information Service, Department of Obstetrics and Gynaecology, Catholic University of the Sacred Heart, Rome, Italy
    Acta Ophthalmol Scand 82:623-4. 2004
    ..To assess pregnancy and neonatal outcomes in a woman accidentally exposed to Verteporfin photodynamic therapy in the third week of pregnancy...
  19. ncbi request reprint Clopidogrel treatment during pregnancy: a case report and a review of literature
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynaecology, Universita Cattolica del Sacro Cuore, Italy
    Intern Med 50:1769-73. 2011
    ..Clopidogrel and aspirin were administrated until one week before delivery and a healthy child was born at 36 weeks of pregnancy by caesarean section, without any complication...
  20. ncbi request reprint A geoprocessing model for the selection of populations most affected by diffuse industrial contamination: the case of oil refinery plants
    Roberto Pasetto
    Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanita, Rome, Italy
    Ann Ist Super Sanita 49:18-23. 2013
    ..The reasons to use municipality instead of census tract populations for environment and health small-area studies of contaminated sites are discussed...
  21. ncbi request reprint Laparoscopic management of a large, twisted, ovarian dermoid cyst during pregnancy: a case report
    Marco De Santis
    Department of Obstetrics and Gynaecology, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, 00168 Rome, Italy
    J Reprod Med 58:271-6. 2013
    ..The diagnosis of mature cystic teratomas during pregnancy presents the vexing problem of weighing the risks of surgery under general anesthetic against the risks of an untreated persistent adnexal mass...
  22. pmc Syphilis Infection during pregnancy: fetal risks and clinical management
    Marco De Santis
    Department of Obstetrics and Gynaecology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Infect Dis Obstet Gynecol 2012:430585. 2012
    ..Prenatal diagnosis of congenital syphilis includes noninvasive and invasive diagnosis. Serological screening during pregnancy and during preconception period should be performed to reduce the incidence of congenital syphilis...
  23. ncbi request reprint A novel route of transplantation of human cord blood stem cells in preimmune fetal sheep: the intracelomic cavity
    Giuseppe Noia
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Stem Cells 21:638-46. 2003
    ..This preliminary study indicates that intracelomic transplantation of human hematopoietic stem cells in fetal lambs is feasible and effective in terms of hematopoietic engraftment...
  24. ncbi request reprint Paternal exposure to ribavirin: pregnancy and neonatal outcome
    Marco De Santis
    Department of Obstetrics and Gynaecology, Telefono Rosso Teratology Information Service, Catholic University of the Sacred Heart, Largo A Gemelli, 8 00168 Rome, Italy
    Antivir Ther 8:73-5. 2003
    ..We report seven cases of newborns conceived within 6 months from the end or during paternal ribavirin exposure...
  25. ncbi request reprint Inherited and acquired thrombophilia: pregnancy outcome and treatment
    Marco De Santis
    Telefono Rosso Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Largo A Gemelli, 8, 00168 Rome, Italy
    Reprod Toxicol 22:227-33. 2006
    ..Appropriate treatment can improve pregnancy outcome without teratogenic effects...
  26. ncbi request reprint Effects of antiretroviral therapy on tube-like network formation of human endothelial cells
    Nicoletta Di Simone
    Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
    Biol Pharm Bull 30:982-4. 2007
    ..Zidovudine and indinavir used in combination do not further strengthen both endothelial cell tubes formation and VEGF secretion. We conclude that zidovudine and indinavir may induce angiogenesis in an in vitro model...
  27. doi request reprint Ecological studies of cancer incidence in an area interested by dumping waste sites in Campania (Italy)
    Lucia Fazzo
    Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanita, Rome, Italy
    Ann Ist Super Sanita 47:181-91. 2011
    ..Statistically significant clusters were detected for liver, lung, leukaemia and soft tissue sarcomas. In the regression analysis, testis cancer showed significant trend with the index of waste-related exposure (RR = 1.18)...
  28. ncbi request reprint Mortality study of employees in a factory of recovery and refining of catalytic converters in Rome, Italy
    Roberto Pasetto
    Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanita, Rome, Italy
    Ann Ist Super Sanita 42:156-62. 2006
    ..The implementation of cohort studies in industrial sites where industrial activities similar to the one here examined are present, are highly recommended...
  29. ncbi request reprint Transabdominal amnioinfusion treatment of severe oligohydramnios in preterm premature rupture of membranes at less than 26 gestational weeks
    Marco De Santis
    Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy
    Fetal Diagn Ther 18:412-7. 2003
    ..To evaluate the efficacy of transabdominal amnioinfusion on feto-neonatal and maternal morbidity and feto-neonatal mortality...
  30. ncbi request reprint Exposure to mirtazapine during pregnancy: a prospective, comparative study of birth outcomes
    Josephine Djulus
    Motherisk Program, Division of Clinical Pharmacology, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Psychiatry 67:1280-4. 2006
    ..Currently, apart from a few case reports and case series in the literature, there are no studies evaluating the safety of this drug during pregnancy...
  31. ncbi request reprint Hemangiomas and other congenital malformations in infants exposed to antiretroviral therapy in utero
    Marco De Santis
    JAMA 291:305. 2004
  32. ncbi request reprint Sacrococcygeal teratoma. Outcome and management. An analysis of 17 cases
    Luigi Perrelli
    Division of Pediatric Surgery, Catholic University of the Sacred Heart, Rome, Italy
    J Perinat Med 30:179-84. 2002
    ..The authors compare their experience of 17 cases of sacrococcygeal teratoma (SCT) with the literature in an attempt to clarify the natural history of this tumor and to identify factors related to its prognosis and management...
  33. ncbi request reprint Risk of drug-induced congenital defects
    Marco De Santis
    Telefono Rosso Teratology Information Service, Institute of Obstetrics and Gynaecology, Catholic University Sacred Heart, Largo A Gemelli 8, Rome 00168, Italy
    Eur J Obstet Gynecol Reprod Biol 117:10-9. 2004
    ..Teratology Information Services can assist both physicians and patients when any doubt exists...
  34. ncbi request reprint Vitamin K antagonists and pregnancy outcome. A multi-centre prospective study
    Christof Schaefer
    Pharmakovigilanz und Beratungszentrum für Embryonaltoxikologie, Berliner Betrieb für Zentrale Gesundheitliche Aufgaben, Spandauer Damm 130, Haus 10, 14050 Berlin, Germany
    Thromb Haemost 95:949-57. 2006
    ..Close follow-up by the obstetrician including level II ultrasound should be recommended in any case of VKA exposure during pregnancy...
  35. ncbi request reprint Fetal exposure to isotretinoin-an international problem
    Facundo Garcia-Bournissen
    Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, University of Toronto, Toronto, Canada
    Reprod Toxicol 25:124-8. 2008
    ..Isotretinoin is a known teratogen. Pregnancy prevention programs aimed at minimizing isotretinoin exposure in pregnancy have been implemented in North America with limited success...