Research Topics
| A DarioSummaryCountry: Italy Publications
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Detail Information
Publications
Pharmacological complications of the chronic baclofen infusion in the severe spinal spasticity. Personal experience and review of the literatureA Dario
Neurosurgical Clinic, University of Insubria, University Hospital of Varese, Italy
J Neurosurg Sci 48:177-81. 2004..To evaluate the pharmacological complications and side effects of the chronic intrathecal baclofen infusion in patients suffering from intractable spinal spasticity in our Department as well as in the literature...
Functional improvement in patients with severe spinal spasticity treated with chronic intrathecal baclofen infusionA Dario
Department of Neurosurgery, Unit of Neurology, Ospedale di Circolo, Varese, Italy
Funct Neurol 16:311-5. 2001..Chronic intrathecal baclofen infusion was seen to produce a functional improvement in patients with severe spinal spasticity, particularly as regards bathing, comfortable wheelchair sitting and mobility...
Relationship between intrathecal baclofen and the central nervous systemA Dario
Neurosurgical Clinic and Department of Structural and Functional Biology, Insubria University, Varese, Italy
Acta Neurochir Suppl 97:461-4. 2007..Finally, the clinically interesting results on the regulation of food intake and blood pressure are highlighted. The preliminary experience on the effects in cortical neuron viability at different concentrations of ITB is reported...
Management of spasticity in multiple sclerosis by intrathecal baclofenA Dario
Neurosurgical Clinic, Insubria University, Varese, Italy
Acta Neurochir Suppl 97:189-92. 2007..The most dangerous side effects are baclofen overdose and withdrawal syndrome. These complications are totally avoidable by adopting an approach attentive to the details regarding the patient, the device, and the procedure...
Intrathecal baclofen does not inhibit the growth of different bacterial species and Candida albicansAlessandro Dario
Neurosurgical Clinic, Ospedale di Circolo e Fondazione Macchi and Insubria University, 21100 Varese, Italy
Surg Neurol 68:168-71; discussion 171. 2007....
The safety of the temozolomide in patients with malignant gliomaAlessandro Dario
Neurosurgical Clinic of Insubria University, Varese, Italy
Curr Drug Saf 1:205-22. 2006..The temozolomide is used also in children but the toxicity could be more frequent...
A case of post-traumatic cervicogenic headache treated by cervical cord stimulationA Dario
Neurosurgical Clinic, University of Insubria, Ospedale Regionale, Viale Borri, 57, I 21100, Varese, Italy
J Headache Pain 6:473. 2005..This report underlines the presence of two pathologies and the relationship between C2 and trigeminal pathways...
A benefit-risk assessment of baclofen in severe spinal spasticityAlessandro Dario
Neurosurgical Clinic of Insubria University, Varese, Italy
Drug Saf 27:799-818. 2004..Since the adverse consequences do not exceed the benefits of oral and intrathecal baclofen for patients with spinal spasticity, the benefit/risk assessment is favourable...
Long-term intrathecal Baclofen infusion in supraspinal spasticity of adulthoodA Dario
Department of Neurosurgery, University of Insubria, Italy
Acta Neurol Scand 105:83-7. 2002..To evaluate long-term results of chronic intrathecal Baclofen infusion on the spasticity, on the spasms and to evaluate the side-effects of the intrathecal Baclofen in patients with supraspinal spasticity...
Extracranial-intracranial bypass for giant aneurysms and complex vascular lesions: a clinical series of 10 patientsC Scamoni
Department of Neurosurgery, University of Insubria, Varese, Italy
J Neurosurg Sci 52:1-9; discussion 9-10. 2008..The purpose of this clinical study is to evaluate the preventive bypass indications, the kind of bypass to use, and the timing of postoperative internal carotid artery (ICA) occlusion in the treatment of complex aneurysms...
Baclofen and potential therapeutic use: studies of neuronal survivalAlessandro Dario
Neurosurgical Clinic, University of Insubria, Via L. Borri 57, 21100 Varese, Italy
Eur J Pharmacol 550:33-8. 2006..Considering the above results, we can conclude that at the used concentrations, this drug is safe and its clinical use should be encouraged...
Blood flow and cord stimulationAlessandro Dario
J Neurosurg 100:357; author reply 357-8. 2004
