Research Topics
| Nereo SegnanSummaryAffiliation: CPO Piemonte Country: Italy Publications
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Publications
Audit system on quality of breast cancer diagnosis and treatment (QT): results of quality indicators on screen-detected lesions in Italy in 2005 and preliminary results for 2006Maria Piera Mano
CPO Piemonte, Torino
Epidemiol Prev 32:77-84. 2008..Specialist Breast Units with adequate case volume would provide the best setting for making audit effective in producing quality improvement...
Estimate of overdiagnosis of breast cancer due to mammography after adjustment for lead time. A service screening study in ItalyEugenio Paci
Clinical and Descriptive Epidemiology Unit, CSPO, Research Institute of the Tuscany Region, Via di San Salvi 12, Firenze, 50135, Italy
Breast Cancer Res 8:R68. 2006..Excess of incidence rates is the expected consequence of service screening. The aim of this paper is to estimate the quota attributable to overdiagnosis in the breast cancer screening programmes in Northern and Central Italy...
Baseline findings of the Italian multicenter randomized controlled trial of "once-only sigmoidoscopy"--SCORENereo Segnan
Unit of Epidemiology, Centro per la Prevenzione Oncologica Piemonte, Azienda Sanitaria Ospedaliero S Giovanni Batista, Via S Francesco da Paola 31, Piemonte, 10123 Turin, Italy
J Natl Cancer Inst 94:1763-72. 2002..We present the baseline screening outcomes...
Comparing attendance and detection rate of colonoscopy with sigmoidoscopy and FIT for colorectal cancer screeningNereo Segnan
CPO Piemonte, Torino, Italy
Gastroenterology 132:2304-12. 2007..We conducted a study to estimate population coverage and detection rate (DR) achievable through different strategies of colorectal cancer (CRC) screening...
Randomized trial of different screening strategies for colorectal cancer: patient response and detection ratesNereo Segnan
Centro Prevenzione Oncologica Regione Piemonte and Azienda Sanitaria Ospedaliera S Giovanni Battista, Torino, Italy
J Natl Cancer Inst 97:347-57. 2005..We compared the participation and detection rates achievable through different strategies of colorectal cancer screening...
Once-only sigmoidoscopy in colorectal cancer screening: follow-up findings of the Italian Randomized Controlled Trial--SCORENereo Segnan
Centro di Prevenzione Oncologica Piemonte and S Giovanni University Hospital, Turin, Italy
J Natl Cancer Inst 103:1310-22. 2011..A single flexible sigmoidoscopy at around the age of 60 years has been proposed as an effective strategy for colorectal cancer (CRC) screening...
Results at recruitment from a randomized controlled trial comparing human papillomavirus testing alone with conventional cytology as the primary cervical cancer screening testGuglielmo Ronco
Unit of Cancer Epidemiology, Centro per la Prevenzione Oncologica, Turin, Italy
J Natl Cancer Inst 100:492-501. 2008..HPV-positive women were directly referred to colposcopy if aged 35 or older; if younger, they were retested after 1 year...
Extension of organised cervical cancer screening programmes in Italy and their process indicatorsGuglielmo Ronco
CPO Piemonte, Torino
Epidemiol Prev 31:33-47. 2007..The unadjusted detection rate ofhistologically confirmed CIN2 or more severe was 2.7 per 1000 screened women (3.0 per 1000, standardised on the Italian population, truncated 25-64)...
Extension of organised cervical cancer screening programmes in Italy and their process indicators: 2007 activityGuglielmo Ronco
CPO Piemonte, Torino
Epidemiol Prev 33:41-56. 2009..0%. The unadjusted detection rate of CIN2 or more severe histology was 2.9 per 1,000 screened women (3.1 standardised on the Italian population, truncated 25-64)...
Extension of organised cervical cancer screening programmes in Italy and their process indicators, 2009 activityGuglielmo Ronco
CPO Piemonte, Torino
Epidemiol Prev 35:39-54. 2011..2%. The unadjusted detection rate of CIN2 or more severe histology was 3.2 per 1,000 screened women (3.2 standardised on the Italian population, truncated 25-64)...
Time trends of process and impact indicators in Italian breast screening programmes: 1998-2007Livia Giordano
Unità di epidemiologia dei tumori, CPO Piemonte, Torino
Epidemiol Prev 33:29-39. 2009..Outcomes related to subsequent screening rounds present analogous performances. These results continue to be consistent with those achieved by other European programmes and reassuring for all Italian mammography screening professionals...
Time trends of process and impact indicators in Italian breast screening programmes--1996-2005Livia Giordano
Unità di epidemiologia dei tumori, CPO Piemonte, Torino
Epidemiol Prev 32:23-36. 2008..Outcomes related to subsequent screening present analogous performances. These results continue to be consistent with those achieved by other European programmes and reassuring for all Italian mammography screening professionals...
Predicting proximal advanced neoplasms at screening sigmoidoscopyCarlo Senore
Unit of Epidemiology, CPO, Piemonte, Torino, Italy
Dis Colon Rectum 47:1331-40. 2004..This study was designed to assess the predictive value for advanced proximal neoplasms (cancer, adenoma > or = 10 mm, or villous component > 20 percent, or severe dysplasia) of the characteristics of distal polyps...
Time trends of process and impact indicators in Italian breast screening programmes (1999-2009)Livia Giordano
Unità di epidemiologia dei tumori, CPO Piemonte, Torino
Epidemiol Prev 35:28-38. 2011..Although further analyses are needed to better interpret these trends, results continue to be consistent with those achieved by other European programmes, and are reassuring for all Italian mammography screening professionals...
Audit on quality of breast cancer diagnosis and treatment in Italy, 2008-2009Antonio Ponti
CPO Piemonte, Torino
Epidemiol Prev 35:87-95. 2011..Specialist breast units with adequate case volume and enough resources would provide the best setting for making audits effective in producing quality improvements with shorter waiting times...
Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: a randomised controlled trialGuglielmo Ronco
Centre for Cancer Prevention, Turin, Italy
Lancet Oncol 11:249-57. 2010..We assessed the efficacy of cervical-cancer screening policies that are based on HPV testing...
Audit system on Quality of breast cancer diagnosis and Treatment (QT): results of quality indicators on screen-detected lesions in Italy for 2006 and preliminary results for 2007Mariano Tomatis
CPO Piemonte, Torino, Italy
Epidemiol Prev 33:83-90. 2009..Specialist Breast Units with adequate case volume and enough resources would provide the best setting for making audit effective in producing quality improvement with a shortening of waiting times...
Time trends of process and impact indicators in Italian breast screening programmes: 1998-2008Livia Giordano
Unità di epidemiologia dei tumori, CPO Piemonte, Turin
Epidemiol Prev 34:27-34. 2010..On the contrary, excess referral rate at first screening persists over time. These results continue to be consistent with those achieved by other European programmes and reassuring for all Italian mammography screening professionals...
Extension of organised cervical cancer screening programmes in Italy and their process indicators: 2008 activityGuglielmo Ronco
CPO Piemonte, Turin
Epidemiol Prev 34:35-51. 2010..0%. The unadjusted detection rate of CIN2 or more severe histology was 3.1 per 1,000 screened women (3.0 standardised on the Italian population, truncated 25-64)...
Comparing different strategies for colorectal cancer screening in Italy: predictors of patients' participationCarlo Senore
Centro Prevenzione Oncologica Regione Piemonte and Azienda Ospedaliero Universitaria S Giovanni Battista di Torino, Turin, Italy
Am J Gastroenterol 105:188-98. 2010..The objective of this study was to study predictors of patients' participation in colorectal cancer (CRC) screening...
The New Technologies for Cervical Cancer Screening randomised controlled trial. An overview of results during the first phase of recruitmentGuglielmo Ronco
Centro per la Prevenzione Oncologica CPO, Torino, Italy
Gynecol Oncol 107:S230-2. 2007..To study the impact of different cervical cancer screening strategies including HPV testing...
Audit system on quality of breast cancer diagnosis and treatment (QT): results from the survey on screen-detected lesions in Italy, 2004Antonio Ponti
CPO Piemonte, Torino
Epidemiol Prev 31:69-75. 2007..Specialist Breast Units with adequate case volumes would provide the best setting for effective audits leading to quality improvement...
Extension of organised cervical cancer screening programmes in Italy and their process indicatorsGuglielmo Ronco
CPO Piemonte, Torino
Epidemiol Prev 32:37-54. 2008..The unadjusted detection rate of histologically confirmed CIN2 or more severe was 2.7 per 1,000 screened women (2.6 standardised on the Italian population, truncated 25-64)...
HPV triage for low grade (L-SIL) cytology is appropriate for women over 35 in mass cervical cancer screening using liquid based cytologyGuglielmo Ronco
Unit of Cancer Epidemiology, Centro per la Prevenzione Oncologica CPO, Via S Francesco da Paola 31, 10123 Turin, Italy
Eur J Cancer 43:476-80. 2007..5% (95%CI 58.3-70.3) at age 35-60. In conclusion, triaging by HPV testing performed better in women aged over 35 years than those younger. For older women, HPV triaging should also be considered for managing those with LSIL cytology...
Human papillomavirus testing and liquid-based cytology in primary screening of women younger than 35 years: results at recruitment for a randomised controlled trialGuglielmo Ronco
Centre for Cancer Prevention CPO, Turin, Italy
Lancet Oncol 7:547-55. 2006..We aimed to compare conventional screening with an experimental strategy in women aged 25-34 years, and investigate the effect of different criteria of referral to define the best methods of HPV screening...
Audit system on Quality of breast cancer diagnosis and Treatment (QT): results of quality indicators on screen-detected lesions in Italy, 2007Maria Piera Mano
CPO Piemonte, Turin
Epidemiol Prev 34:81-8. 2010..Specialist Breast Units with adequate case volume and enough resources would provide the best setting for making audits effective in producing quality improvements with a shorter waiting times...
[Audit system on quality of breast cancer diagnosis and treatment: results of quality indicators on screen-detected lesions in Italy, 2010]Antonio Ponti
CPO Piemonte, Torino
Epidemiol Prev 36:87-95. 2012..Specialist Breast Units with adequate case volume and enough resources would provide the best setting for making monitoring effective in producing quality improvements with shorter waiting times...
[Extension of organised cervical cancer screening programmes in Italy and their process indicators, 2010 activity]Guglielmo Ronco
CPO Piemonte, Torino
Epidemiol Prev 36:39-54. 2012..0%. The unadjusted detection rate of CIN2 or more severe histology was 3.2 per 1,000 screened women (3.5 standardised on the Italian population, truncated 25-64)...
The impact of different communication and organizational strategies on mammography screening uptake in women aged 40-45 yearsLivia Giordano
Unit of Epidemiology CPO Piemonte, Center for Cancer Prevention, Turin, Italy
Eur J Public Health 22:413-8. 2012..The aim of the study was to evaluate the impact of different information approaches, women's socio-demographic characteristics and organizational factors on mammography screening uptake...
Human papillomavirus testing and liquid-based cytology: results at recruitment from the new technologies for cervical cancer randomized controlled trialGuglielmo Ronco
Unit of Cancer Epidemiology, Centro per la Prevenzione Oncologica Piemonte, 10123 Turin, Italy
J Natl Cancer Inst 98:765-74. 2006....
Compliance with clinical practice guidelines for breast cancer treatment: a population-based study of quality-of-care indicators in ItalyCarlotta Sacerdote
Cancer Epidemiology Unit, San Giovanni Battista Hospital, CPO Piemonte and University of Turin, Turin, Italy
BMC Health Serv Res 13:28. 2013..abstract:..
Time trends of process and impact indicators in Italian mammography screening programmes--1996-2004Livia Giordano
CPO Piemonte, Torino
Epidemiol Prev 31:21-32. 2007..The website of the National Centre for Screening Monitoring (ONS) is http://www.osservatorionazionalescreening.it...
The beginning of a decline in breast cancer incidence in Italy?Roberto Zanetti
Registro Tumori Piemonte, Turin, Italy
Tumori 94:293-6. 2008..This observation may be relevant to other geographical areas where organized or spontaneous screening reached a plateau after an increase in the preceding years...
Mammographic screening programmes in Europe: organization, coverage and participationLivia Giordano
Epidemiologist, Epidemiology Unit, CPO Piemonte, AOU S Giovanni Battista, Turin, Italy
J Med Screen 19:72-82. 2012..To summarize participation and coverage rates in population mammographic screening programmes for breast cancer in Europe...
[Time trends of process and impact indicators in Italian breast screening programmes (2000-2010)]Livia Giordano
Unità di epidemiologia dei tumori, CPO Piemonte, Torino
Epidemiol Prev 36:28-38. 2012..Although further analyses are needed to better interpret these trends, results continue to be consistent with those achieved by other European programmes, and they are reassuring for all Italian breast cancer screening professionals...
HPV testing for primary cervical cancer screeningGuglielmo Ronco
Unit of Cancer Epidemiology, CPO Piemonte, Torino 10123, Italy
Lancet 370:1740-2. 2007
Improving the quality of communication in organised cervical cancer screening programmesLivia Giordano
CPO Piemonte, Torino, Italy
Patient Educ Couns 72:130-6. 2008..To provide health professionals involved in cervical cancer screening with an insight into the complex issues relating to communication about screening and to provide a framework for a more effective communication strategy...
[Epidemiologic research in Italy: a comparison with the rest of Europe and the United States]Federica Gallo
Centro di riferimento per l epidemiologia e prevenzione oncologica in Piemonte e Azienda ospedaliero universitaria San Giovanni Battista, Torino, Italy
Epidemiol Prev 35:12-7. 2011..This is accomplished for both scientific published papers and grants obtained...
Acceptability and side-effects of colonoscopy and sigmoidoscopy in a screening settingCarlo Senore
Centro Prevenzione Oncologica Regione Piemonte and Azienda Ospedaliero Universitaria S Giovanni Battista di Torino, V San Francesco da Paola 31, 10123 Torino, Italy
J Med Screen 18:128-34. 2011..Quantitative information on adverse reactions associated with colorectal cancer (CRC) screening tests is useful to estimate the balance between benefit and risk in different strategies...
Impact of the AutoPap (currently Focalpoint) primary screening system location guide use on interpretation time and diagnosisGuglielmo Ronco
Centro per la Prevenzione Oncologica del Piemonte CPO, Turin, Italy
Cancer 99:83-8. 2003..For smears indicated to require further review, the system provides maps (PapMaps) to identify the most abnormal areas of the smear...
Accuracy of liquid based versus conventional cytology: overall results of new technologies for cervical cancer screening: randomised controlled trialGuglielmo Ronco
Unit of Cancer Epidemiology, Centre for Cancer Prevention, Via S Francesco da Paola 31 10123 Turin, Italy
BMJ 335:28. 2007..To compare the accuracy of conventional cytology with liquid based cytology for primary screening of cervical cancer...
A high positive predictive value algorithm using hospital administrative data identified incident cancer casesIleana Baldi
Cancer Epidemiology Unit, University of Turin and C P O Piemonte, San Giovanni Battista Hospital, Via Santena 7, 10126 Turin, Italy
J Clin Epidemiol 61:373-9. 2008..We have developed and validated an algorithm based on Piedmont hospital discharge abstracts for ascertainment of incident cases of breast, colorectal, and lung cancer...
[Results and cost evaluation of triage with high risk HPV test in cervical cancer screening. A pilot study in Piedmont (North-West Italy)]Corrado Magnani
SCDU Epidemiologia dei Tumori, CPO Piemonte, AOU Maggiore di Novara e Università del Piemonte orientale, Novara, Italy
Epidemiol Prev 36:88-94. 2012..The study was conducted in respect to: participation, predictive value, and cost analysis, separately for ASC-US and LSIL cytology...
Prevalence of human papillomavirus infection in women in Turin, ItalyGuglielmo Ronco
Unit of Cancer Epidemiology, CPO Piemonte, ASO S Giovanni Battista, via San Francesco da Paola 31, 10123 Turin, Italy
Eur J Cancer 41:297-305. 2005..In conclusion, overall, the female population of Turin showed an HPV prevalence that is intermediate compared with worldwide levels...
Modelling patterns of clearance of HPV-16 infection and vaccination efficacyIacopo Baussano
SCDU di Epidemiologia dei Tumori, Servizio di Statistica Medica, CPO Piemonte, Novara, Italy
Vaccine 29:1270-7. 2011....
What information do breast cancer screening programmes provide to Italian women?Livia Giordano
Unit of Epidemiology, CPO Piemonte, ASO San Giovanni Battista di Torino, Via S Francesco da Paola 31, 10124 Turin, Italy
Eur J Public Health 15:66-9. 2005..In the screening context, invitation letters and leaflets often represent the principal source of information...
[Community interventions among tobacco control strategies: coping with their definition and evaluation]Paolo D'Elia
Centro di riferimento per l epidemiologia e la prevenzione oncologica, Piemonte, Torino
Epidemiol Prev 32:156-61. 2008..To reach this goal it may be helpful to combine study designs allowing for both quantitative and qualitative assessments, such as action research and participatory evaluation research...
Accessibility as a major determinant of radiotherapy underutilization: a population based studyEva Pagano
Unit of Cancer Epidemiology, Ospedale S Giovanni Battista, CPO Piemonte, University of Turin, Italy
Health Policy 80:483-91. 2007..A survey was conducted of radiotherapy (RT) resources and utilization in a northwestern Italian Region in order to assess geographical variations in radiotherapy utilization rates, and the effects of infrastructure supply on accessibility...
Sun exposure prior to diagnosis is associated with improved survival in melanoma patients: results from a long-term follow-up study of Italian patientsStefano Rosso
CPO, Cancer Prevention Centre, Piedmont Cancer Registry, via San Francesco da Paola 31, Turin, Italy
Eur J Cancer 44:1275-81. 2008..This study, with similar methods and a longer follow-up, confirms the finding that sun exposure prior to diagnosis of melanoma is associated with improved survival...
Audit system on Quality of breast cancer diagnosis and Treatment (QT): results from the survey on screen-detected lesions in Italy, 2003-2004Antonio Ponti
Centro Prevenzione Oncologica, Torino
Epidemiol Prev 30:59-63. 2006..Specialist Breast Units with adequate case volume would provide the best setting for making audit effective in producing quality improvement...
The impact of new technologies in cervical cancer screening: results of the recruitment phase of a large randomised controlled trial from a public health perspectivePaolo Giorgi-Rossi
Agency for Public Health, Lazio Region, Rome, Italy
Int J Cancer 121:2729-34. 2007..If HPV testing is applied with cytology-triage, a single HPV test may cost 20-30% more than a conventional Pap to result in the same overall cost per CIN2+ detected...
Evaluation of service mammography screening impact in Italy. The contribution of hazard analysisEugenio Paci
Clinical and Descriptive Epidemiology Unit, CSPO, Research Institute of the Tuscany Region, Firenze, Italy
Eur J Cancer 44:858-65. 2008..96 in the [5-10] year time window, suggesting minimal or any length bias. Consistent with the results of randomised trials, these analyses of service screening data document a mortality reduction of 36% at 5-10 years after diagnosis...
Re: Breast cancer incidence, 1980-2006: combined roles of menopausal hormone therapy, screening mammography, and estrogen receptor statusAntonio Ponti
J Natl Cancer Inst 99:1817-8; author reply 1819. 2007
[Experimental assessment of pros and cons: we shouldn't miss this chance]Nereo Segnan
Epidemiol Prev 31:183-4. 2007
Ascertainment and evaluation of interval cancers in population-based mammography screening programmes: a collaborative study in four European centresSven Törnberg
Cancer Screening Unit, Oncologic Centre M8, Karolinska University Hospital, S 17176 Stockholm, Sweden
J Med Screen 12:43-9. 2005....
Early diagnosis, not differential treatment, explains better survival in service screeningEugenio Paci
Unit of Clinical and Descriptive Epidemiology, Centre for Study and Prevention of Cancer, Research Institute of Tuscany Region, Via di San Salvi 12, 50125 Firenze, Florence, Italy
Eur J Cancer 41:2728-34. 2005..The survival analysis by specific subgroups did not support the hypothesis that the difference in prognosis was attributable to differential treatment...
History of negative colorectal endoscopy and risk of rectosigmoid neoplasms at screening flexible sigmoidoscopyLuigina Bonelli
Secondary Prevention and Screening, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Int J Colorectal Dis 21:105-13. 2006....
Re: Role of detection method in predicting breast cancer survival: analysis of randomized screening trialsEugenio Paci
J Natl Cancer Inst 97:1853-4; author reply 1854. 2005
Human papillomavirus typing with GP5+/6+ polymerase chain reaction reverse line blotting and with commercial type-specific PCR kitsAnna Gillio-Tos
Unit of Cancer Epidemiology, C E R M S, University of Turin, Via Santena 7, 10126 Turin, Italy
J Clin Virol 36:126-32. 2006..Infection with human papillomavirus (HPV) is a necessary step in the progression to cervical cancer. Many methods for HPV testing are currently available, most developed to detect pools of HPV types...
Activity level and process indicators of organised programmes for cervical cancer screening in ItalyGuglielmo Ronco
Centro Prevenzione Oncologica, Torino
Epidemiol Prev 30:27-40. 2006..Despite this rise, quality indicators were stable. However, in a few programmes, the use of excessively broad criteria in the interpretation of cytology decides an excessively high rate of referrals to colposcopy...
[Use of discharge records to define the oncological diagnoses for outpatient radiotherapy patients]Eva Pagano
Epidemiologia dei tumori, Universita di Torino
Epidemiol Prev 30:132-8. 2006..The procedure is based on the record linkage between discharge records (SDO) and outpatients records (PA), in order to obtain clinical information from the diagnosis related to possible admissions of the patients...
[Adapting clinical practice guidelines to a regional oncology network: the Piedmont experience]Elena Gelormino
Epidemiologia dei tumori, ASO S Giovanni Battista e CPO Piemonte, Torino
Epidemiol Prev 31:25-33. 2007..To develop a method for adapting the best available cancer practice guidelines (CPGs) to the regional oncology network in Piedmont (NW of Italy, with about 4.3 million residents)...
[Effective laws for tobacco control: EU directives and Italian legislation]Lorena Charrier
Centro di riferimento per l'epidemiologia e la prevenzione oncologica in Piemonte, Torino
Epidemiol Prev 30:366-9. 2006..The positive impact of this ban in these countries suggests that it should be considered a priority in the European policies against tobacco in order to reduce the gap between literature recommendations and actions...
[Building new bridges]Nereo Segnan
Epidemiol Prev 27:323-7. 2003
