Calogero Cammà

Summary

Affiliation: Consiglio Nazionale delle Ricerche
Country: Italy

Publications

  1. doi request reprint Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection
    Salvatore Petta
    Cattedra ed Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
    Am J Gastroenterol 103:1136-44. 2008
  2. ncbi request reprint Treatment of hepatitis C: critical appraisal of the evidence
    Calogero Cammà
    University of Palermo, Cattedra di Gastroenterologia, Istituto di Clinica Medica, Italy
    Expert Opin Pharmacother 6:399-408. 2005
  3. ncbi request reprint Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C
    Calogero Cammà
    Unità Operativa di Gastroenterologia, University of Palermo, Italy
    Hepatology 43:64-71. 2006
  4. ncbi request reprint Treatment of hepatocellular carcinoma in compensated cirrhosis with radio-frequency thermal ablation (RFTA): a prospective study
    Calogero Cammà
    Cattedra e Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
    J Hepatol 42:535-40. 2005
  5. ncbi request reprint The impact of antiviral treatments on the course of chronic hepatitis C: an evidence-based approach
    Calogero Cammà
    Ist of Clinica Medica I, Piazza della Cliniche 2, 90100 Palermo, Italy
    Curr Pharm Des 10:2123-30. 2004
  6. ncbi request reprint Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: a meta-analysis of individual patient data
    Calogero Cammà
    IBIM, Consiglio Nazionale delle Ricerche, Palermo, Italy
    Hepatology 39:333-42. 2004
  7. ncbi request reprint Time course of insulin resistance during antiviral therapy in non-diabetic, non-cirrhotic patients with genotype 1 HCV infection
    Salvatore Petta
    Cattedra ed Unità Operativa di Gastroenterologia, Universita di Palermo, Palermo, Italy
    Antivir Ther 14:631-9. 2009
  8. doi request reprint Vitamin D levels and IL28B polymorphisms are related to rapid virological response to standard of care in genotype 1 chronic hepatitis C
    Salvatore Petta
    Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
    Antivir Ther 17:823-31. 2012
  9. doi request reprint Visceral adiposity index is associated with histological findings and high viral load in patients with chronic hepatitis C due to genotype 1
    Salvatore Petta
    Dipartimento Biomedico di Medicina Interna e Specialistica, Cattedra di Gastroenterologia, DiBiMIS, Palermo, Italy
    Hepatology 52:1543-52. 2010
  10. doi request reprint Hepatic steatosis and insulin resistance are associated with severe fibrosis in patients with chronic hepatitis caused by HBV or HCV infection
    Salvatore Petta
    Sezione di Gastroenterologia, University of Palermo, Palermo, Italy
    Liver Int 31:507-15. 2011

Collaborators

Detail Information

Publications44

  1. doi request reprint Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection
    Salvatore Petta
    Cattedra ed Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
    Am J Gastroenterol 103:1136-44. 2008
    ..We aimed to assess whether increasing degrees of IR, up to overt diabetes, are linked to steatosis and higher stages of fibrosis in patients with CHC resulting from genotype 1 HCV (G1-HCV)...
  2. ncbi request reprint Treatment of hepatitis C: critical appraisal of the evidence
    Calogero Cammà
    University of Palermo, Cattedra di Gastroenterologia, Istituto di Clinica Medica, Italy
    Expert Opin Pharmacother 6:399-408. 2005
    ..The magnitude of this effect is low and the observed benefit may be due to spurious associations. The preventive effect is more evident among sustained responders to IFN...
  3. ncbi request reprint Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C
    Calogero Cammà
    Unità Operativa di Gastroenterologia, University of Palermo, Italy
    Hepatology 43:64-71. 2006
    ..IR is a risk factor for moderate/severe steatosis, especially in men. Moderate/severe steatosis has clinical relevance, being associated with advanced fibrosis and hyporesponsiveness to antiviral therapy...
  4. ncbi request reprint Treatment of hepatocellular carcinoma in compensated cirrhosis with radio-frequency thermal ablation (RFTA): a prospective study
    Calogero Cammà
    Cattedra e Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
    J Hepatol 42:535-40. 2005
    ..To assess the effectiveness and the safety of radio-frequency thermal ablation (RFTA) in patients with hepatocellular carcinoma (HCC) < or = 5 cm in compensated cirrhosis...
  5. ncbi request reprint The impact of antiviral treatments on the course of chronic hepatitis C: an evidence-based approach
    Calogero Cammà
    Ist of Clinica Medica I, Piazza della Cliniche 2, 90100 Palermo, Italy
    Curr Pharm Des 10:2123-30. 2004
    ..The magnitude of this effect is low and the observed benefit might be due to spurious associations. The preventive effect is more evident among sustained responders to interferon...
  6. ncbi request reprint Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: a meta-analysis of individual patient data
    Calogero Cammà
    IBIM, Consiglio Nazionale delle Ricerche, Palermo, Italy
    Hepatology 39:333-42. 2004
    ..The beneficial effects of peginterferon on liver histology are closely related to virologic response...
  7. ncbi request reprint Time course of insulin resistance during antiviral therapy in non-diabetic, non-cirrhotic patients with genotype 1 HCV infection
    Salvatore Petta
    Cattedra ed Unità Operativa di Gastroenterologia, Universita di Palermo, Palermo, Italy
    Antivir Ther 14:631-9. 2009
    ..We aimed to evaluate the time course of IR in response to antiviral therapy in non-diabetic, non-cirrhotic G1 HCV patients and to assess the effect of metabolic factors on sustained virological response (SVR)...
  8. doi request reprint Vitamin D levels and IL28B polymorphisms are related to rapid virological response to standard of care in genotype 1 chronic hepatitis C
    Salvatore Petta
    Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
    Antivir Ther 17:823-31. 2012
    ..We assessed whether 25-hydroxyvitamin D (25[OH]D) serum levels are linked to RVR and can be used together with IL28B to construct a pretreatment model to predict RVR...
  9. doi request reprint Visceral adiposity index is associated with histological findings and high viral load in patients with chronic hepatitis C due to genotype 1
    Salvatore Petta
    Dipartimento Biomedico di Medicina Interna e Specialistica, Cattedra di Gastroenterologia, DiBiMIS, Palermo, Italy
    Hepatology 52:1543-52. 2010
    ..04), and fibrosis (OR 2.608, 95% CI 1.565-4.345, P < 0.001) were independently associated with moderate to severe necroinflammatory activity. No independent associations were found between VAI score and both fibrosis and SVR...
  10. doi request reprint Hepatic steatosis and insulin resistance are associated with severe fibrosis in patients with chronic hepatitis caused by HBV or HCV infection
    Salvatore Petta
    Sezione di Gastroenterologia, University of Palermo, Palermo, Italy
    Liver Int 31:507-15. 2011
    ..We aimed to assess the prevalence and the factors related to steatosis and IR in CHB patients, compared with CHC subjects, and to evaluate the potential association between these features and fibrosis severity...
  11. ncbi request reprint Cost-effectiveness of sofosbuvir-based triple therapy for untreated patients with genotype 1 chronic hepatitis C
    Salvatore Petta
    Sezione di Gastroenterologia, Di Bi M I S, University of Palermo, Palermo, Italy
    Hepatology 59:1692-705. 2014
    ..The models were sensitive to SOF prices and to likelihood of sustained virological response...
  12. doi request reprint Assessment of treatment response in hepatocellular carcinoma: a review of the literature
    Marcello Maida
    Section of Gastroenterology, DiBiMIS, University of Palermo, Piazza delle Cliniche 2, Palermo, Italy
    Future Oncol 9:845-54. 2013
    ..The purpose of this brief review is to compare data in literature regarding the application and the performance of mRECIST in clinical practice, and to discuss unclear and open issues...
  13. doi request reprint Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis C
    Salvatore Petta
    Cattedra ed Unità Operativa di Gastroenterologia, DiBiMIS, University of Palermo, Italy
    Hepatology 51:1158-67. 2010
    ..Conclusion: G1 CHC patients had low 25(OH)D serum levels, possibly because of reduced CYP27A1 expression. Low vitamin D is linked to severe fibrosis and low SVR on interferon (IFN)-based therapy...
  14. doi request reprint Retinol-binding protein 4: a new marker of virus-induced steatosis in patients infected with hepatitis c virus genotype 1
    Salvatore Petta
    Cattedra ed Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
    Hepatology 48:28-37. 2008
    ..045; 95% confidence interval, 1.020 to 1.070; P = 0.0004), whereas waist circumference was associated with moderate-severe steatosis in NAFLD (odds ratio, 1.095; 95% confidence interval, 1.007 to 1.192; P = 0.03)...
  15. doi request reprint Retreatment with pegylated interferon plus ribavirin of chronic hepatitis C non-responders to interferon plus ribavirin: a meta-analysis
    Calogero Cammà
    Cattedra di Gastroenterologia, Dipartimento Biomedico di Medicina Interna e Specialistica, University of Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy
    J Hepatol 51:675-81. 2009
    ..We aimed to focus on SVR rates and to identify factors influencing them in this meta-analysis...
  16. pmc Serum γ-glutamyl transferase levels, insulin resistance and liver fibrosis in patients with chronic liver diseases
    Salvatore Petta
    Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
    PLoS ONE 7:e51165. 2012
    ....
  17. doi request reprint IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease
    Salvatore Petta
    Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Italy
    J Hepatol 56:1356-62. 2012
    ..The main outcomes of the study were to assess whether IL28B rs12979860 and rs8099917 polymorphisms, together with PNPLA3 rs738409 C>G polymorphism, are associated with lobular inflammation and fibrosis, in NAFLD patients...
  18. doi request reprint Insulin resistance is a risk factor for esophageal varices in hepatitis C virus cirrhosis
    Calogero Cammà
    Cattedra and Unità Operativa di Gastroenterologia, Di Bi M I S, University of Palermo, Italy
    Hepatology 49:195-203. 2009
    ....
  19. ncbi request reprint When and how to treat acute hepatitis C?
    Anna Licata
    Cattedra di Gastroenterologia, Istituto di Clinica Medica I, University of Palermo, Piazza delle Cliniche, 2, 90127 Palermo, Italy
    J Hepatol 39:1056-62. 2003
    ..Appropriate treatment of acute hepatitis C is still a matter of controversy due to the lack of large controlled trials...
  20. doi request reprint High liver RBP4 protein content is associated with histological features in patients with genotype 1 chronic hepatitis C and with nonalcoholic steatohepatitis
    Salvatore Petta
    Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Italy
    Dig Liver Dis 43:404-10. 2011
    ..To investigate the hepatic expression of retinol-binding protein-4 (RBP4) in chronic hepatitis C (CHC) and nonalcoholic steatohepatitis (NASH) patients, and its association with biochemical and histological patterns of liver damage...
  21. ncbi request reprint Body mass index and liver stiffness affect accuracy of ultrasonography in detecting steatosis in patients with chronic hepatitis C virus genotype 1 infection
    Fabio Salvatore Macaluso
    Sezione di Gastroenterologia, Dipartimento Biochimico di Medicina Interna e Specialistica, University of Palermo, Palermo, Italy Electronic address
    Clin Gastroenterol Hepatol 12:878-884.e1. 2014
    ..We assessed its accuracy in detecting steatosis and factors that affect its diagnostic performance in consecutive patients with chronic hepatitis C virus genotype 1 infection...
  22. ncbi request reprint Effects of IL28B rs12979860 CC genotype on metabolic profile and sustained virologic response in patients with genotype 1 chronic hepatitis C
    Salvatore Petta
    Division of Gastroenterology, Dipartimento Biomedico di Medicina Interna e Specialistica, University of Palermo, Palermo, Italy
    Clin Gastroenterol Hepatol 11:311-7.e1. 2013
    ..We tested the association between the IL28B rs12979860 single-nucleotide polymorphism and metabolic features, including IR, and evaluated their effects on SVR...
  23. ncbi request reprint Prevention of hepatocellular carcinoma
    Antonio Craxi
    Cattedra di Gastroenterologia, University of Palermo, Clinica Medica I, Piazza della Cliniche 2, 90127, Italy
    Clin Liver Dis 9:329-46, viii. 2005
    ....
  24. ncbi request reprint Does chemotherapy prevent HCV-related hepatocellular carcinoma? Cons
    Antonio Craxi
    Cattedra di Gastroenterologia, DiBiMIS, University of Palermo, Italy
    Dig Liver Dis 42:S287-92. 2010
    ..Further large-scale multicenter randomized controlled trials may prove useful to evaluate the benefit on overall survival...
  25. doi request reprint A meta-analysis of survival rates of untreated patients in randomized clinical trials of hepatocellular carcinoma
    Giuseppe Cabibbo
    Cattedra di Gastroenterologia, DiBiMIS, University of Palermo, Italy
    Hepatology 51:1274-83. 2010
    ..Conclusion: This meta-analysis confirms the heterogeneity of behavior of untreated HCC and provides a sound basis for stratifying patients with HCC according to expected survival in future trials of new anti-cancer agents...
  26. pmc NT pro BNP plasma level and atrial volume are linked to the severity of liver cirrhosis
    Anna Licata
    Sezione di Gastroenterologia, Dipartimento Biomedico di Medicina Interna e Specialistica, Di Bi M I S, University of Palermo, Palermo, Italy
    PLoS ONE 8:e68364. 2013
    ....
  27. doi request reprint Cost-effectiveness of sorafenib treatment in field practice for patients with hepatocellular carcinoma
    Calogero Cammà
    Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Italy
    Hepatology 57:1046-54. 2013
    ..Results were sensitive to BSC survival rate, and sorafenib treatment duration...
  28. ncbi request reprint Hyperuricaemia: another metabolic feature affecting the severity of chronic hepatitis because of HCV infection
    Salvatore Petta
    Cattedra di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
    Liver Int 32:1443-50. 2012
    ..Several works observed a link between uric acid serum levels and clinical and histological features of nonalcoholic fatty liver disease. An association between chronic hepatitis C (CHC) and uric acid levels has been poorly investigated...
  29. doi request reprint Fecal calprotectin in clinical practice: a noninvasive screening tool for patients with chronic diarrhea
    Anna Licata
    Sezione e U O C di Gastroenterologia, Di Bi M I S, Universita di Palermo, Palermo, Italy
    J Clin Gastroenterol 46:504-8. 2012
    ..Fecal calprotectin (FC) can be easily measured in the stool, being released by leukocytes in inflammatory conditions...
  30. doi request reprint Causes of and prevention strategies for hepatocellular carcinoma
    Giuseppe Cabibbo
    Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
    Semin Oncol 39:374-83. 2012
    ..The pooling of data from the literature suggests a slight preventive effect of antiviral therapy on HCC development in patients with HCV-related cirrhosis, but the preventive effect is limited to sustained virological responders...
  31. ncbi request reprint Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway
    Danilo Di Bona
    Cattedra e Unità Operativa di Gastroenterologia, Dipartimento Biomedico e di Medicina Specialistica, University of Palermo, Palermo, Italy
    J Hepatol 45:271-9. 2006
    ....
  32. pmc Hyperferritinemia is a risk factor for steatosis in chronic liver disease
    Anna Licata
    Gastroenterology and Hepatology Unit, Department of Internal Medicine, University of Palermo, 90127 Palermo, Italy
    World J Gastroenterol 15:2132-8. 2009
    ..To investigate the relationship between ferritin and steatosis in patients with chronically abnormal liver function tests (LFTs) and high ferritin level...
  33. pmc Glucokinase regulatory protein gene polymorphism affects liver fibrosis in non-alcoholic fatty liver disease
    Salvatore Petta
    Sezione di Gastroenterologia, Dipartimento Biomedico di Medicina Interna e Specialistica, University of Palermo, Palermo, Italy
    PLoS ONE 9:e87523. 2014
    ..We aimed to assess whether GCKR rs780094 C→T SNP influences the expression of steatosis, lobular inflammation and fibrosis in NAFLD patients, after correction for PNPLA3 genotype...
  34. doi request reprint Treatment of hepatocellular carcinoma: present and future
    Chiara Genco
    Section of Gastroenterology, DiBiMIS, University of Palermo, Palermo, Italy
    Expert Rev Anticancer Ther 13:469-79. 2013
    ....
  35. pmc Natural history of untreatable hepatocellular carcinoma: A retrospective cohort study
    Giuseppe Cabibbo
    Giuseppe Cabibbo, Marcello Maida, Chiara Genco, Pietro Parisi, Marco Peralta, Michela Antonucci, Giuseppe Brancatelli, Calogero Cammà, Antonio Craxì, Vito Di Marco, Section of Gastroenterology, Department of Internal Medicine and Biomedical Specialist, University of Palermo, Palermo 90127, Italy
    World J Hepatol 4:256-61. 2012
    ..To investigate the clinical course of untreatable hepatocellular carcinoma (HCC) identified at any stage and to identify factors associated with mortality...
  36. ncbi request reprint Cost-effectiveness of boceprevir or telaprevir for untreated patients with genotype 1 chronic hepatitis C
    Calogero Cammà
    Sezione di Gastroenterologia, Di Bi M I S, University of Palermo, Italy
    Hepatology 56:850-60. 2012
    ..42 with TVR-IL28B. ICER compared with DT was € 8.304 per LYG for BOC-RVR and € 11.455 per LYG for TVR-IL28B. The model was highly sensitive to IL28B CC genotype, likelihood of RVR and sustained virologic response, and BOC/TVR prices...
  37. ncbi request reprint Transarterial chemoembolization for unresectable hepatocellular carcinoma: meta-analysis of randomized controlled trials
    Calogero Cammà
    National Council of Research, Istituto Metodologie Diagnostiche Avanzate, Palermo, Italy
    Radiology 224:47-54. 2002
    ..To review the available evidence of chemoembolization for unresectable hepatocellular carcinoma (HCC)...
  38. ncbi request reprint Interferon-alpha for HBeAg-positive chronic hepatitis B
    Antonio Craxi
    Cattedra di Gastroenterologia, Istituto di Clinica Medica 1, University of Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy
    J Hepatol 39:S99-105. 2003
  39. doi request reprint Is the efficacy of sorafenib treatment in patients with hepatocellular carcinoma affected by age?
    Giuseppe Cabibbo
    Section of Gastroenterology, Di Bi Mi S, University of Palermo, Italy
    Expert Rev Anticancer Ther 13:1355-61. 2013
    ..The aim of this brief review is to highlight the main concerns, pitfalls and warnings regarding the management of HCC in elderly patients, with particular focus on systemic therapy with sorafenib. ..
  40. doi request reprint Meta-analysis of the placebo rates of clinical relapse and severe endoscopic recurrence in postoperative Crohn's disease
    Sara Renna
    Dipartimento di Medicina, Pneumologia e Fisiologia della Nutrizione Umana, Universita di Palermo, Palermo, Italy
    Gastroenterology 135:1500-9. 2008
    ..The aim of this meta-analysis was to focus on knowledge of the placebo rates of relapse and recurrence in postoperative CD and to identify factors influencing these rates...
  41. pmc Staging systems of hepatocellular carcinoma: a review of literature
    Marcello Maida
    Marcello Maida, Emanuele Orlando, Calogero Cammà, Giuseppe Cabibbo, Section of Gastroenterology, DiBiMIS, University of Palermo, 90127 Palermo, Italy
    World J Gastroenterol 20:4141-50. 2014
    ..The aim of this review is to highlight the main tools for assessing the prognosis of HCC and the main concerns, pitfalls and warnings regarding its staging systems currently in use. ..
  42. ncbi request reprint Treatment options in HBV
    Antonio Craxi
    Clinica Medica I, Cattedra di Gastroenterologia, University of Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy
    J Hepatol 44:S77-83. 2006
    ..Adefovir, excluding cost, is preferable to lamivudine as a first-choice because there is less chance of inducing resistance. The long-term benefit of lamivudine and adefovir and the role of combinations is under investigation...
  43. doi request reprint Genetic predisposition to thrombophilia in inflammatory bowel disease
    Maria Cappello
    Sezione e U O C di Gastroenterologia, Palermo, Italy
    J Clin Gastroenterol 45:e25-9. 2011
    ..Inflammatory bowel disease (IBD) is linked to a definite risk of thromboembolic events (TE), but data on the role of prothrombotic genetic mutations are conflicting...
  44. doi request reprint Systematic review by meta-analyses on the possible role of TNF-alpha polymorphisms in association with Alzheimer's disease
    Danilo Di Bona
    Dipartimento di Biopatologia e Metodologie Biomediche, University of Palermo, Italy
    Brain Res Rev 61:60-8. 2009
    ..Current findings support an association between -850 C>T polymorphism and the risk of developing AD; hence, they strengthen the suggestion of a potential role for anti-TNF therapy to maintain physiologic levels of TNF-alpha...