Research Topics
Genomes and GenesSpecies | Calogero CammàSummaryAffiliation: Consiglio Nazionale delle Ricerche Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infectionSalvatore Petta
Cattedra ed Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
Am J Gastroenterol 103:1136-44. 2008..We aimed to assess whether increasing degrees of IR, up to overt diabetes, are linked to steatosis and higher stages of fibrosis in patients with CHC resulting from genotype 1 HCV (G1-HCV)...- Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis CCalogero Cammà
Unità Operativa di Gastroenterologia, University of Palermo, Italy
Hepatology 43:64-71. 2006..IR is a risk factor for moderate/severe steatosis, especially in men. Moderate/severe steatosis has clinical relevance, being associated with advanced fibrosis and hyporesponsiveness to antiviral therapy... - Treatment of hepatocellular carcinoma in compensated cirrhosis with radio-frequency thermal ablation (RFTA): a prospective studyCalogero Cammà
Cattedra e Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
J Hepatol 42:535-40. 2005..To assess the effectiveness and the safety of radio-frequency thermal ablation (RFTA) in patients with hepatocellular carcinoma (HCC) < or = 5 cm in compensated cirrhosis... - Treatment of hepatitis C: critical appraisal of the evidenceCalogero Cammà
University of Palermo, Cattedra di Gastroenterologia, Istituto di Clinica Medica, Italy
Expert Opin Pharmacother 6:399-408. 2005..The magnitude of this effect is low and the observed benefit may be due to spurious associations. The preventive effect is more evident among sustained responders to IFN... - The impact of antiviral treatments on the course of chronic hepatitis C: an evidence-based approachCalogero Cammà
Ist of Clinica Medica I, Piazza della Cliniche 2, 90100 Palermo, Italy
Curr Pharm Des 10:2123-30. 2004..The magnitude of this effect is low and the observed benefit might be due to spurious associations. The preventive effect is more evident among sustained responders to interferon... - Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: a meta-analysis of individual patient dataCalogero Cammà
IBIM, Consiglio Nazionale delle Ricerche, Palermo, Italy
Hepatology 39:333-42. 2004..The beneficial effects of peginterferon on liver histology are closely related to virologic response... - Time course of insulin resistance during antiviral therapy in non-diabetic, non-cirrhotic patients with genotype 1 HCV infectionSalvatore Petta
Cattedra ed Unità Operativa di Gastroenterologia, Universita di Palermo, Palermo, Italy
Antivir Ther 14:631-9. 2009..We aimed to evaluate the time course of IR in response to antiviral therapy in non-diabetic, non-cirrhotic G1 HCV patients and to assess the effect of metabolic factors on sustained virological response (SVR)... - Visceral adiposity index is associated with histological findings and high viral load in patients with chronic hepatitis C due to genotype 1Salvatore Petta
Dipartimento Biomedico di Medicina Interna e Specialistica, Cattedra di Gastroenterologia, DiBiMIS, Palermo, Italy
Hepatology 52:1543-52. 2010..CONCLUSION: In G1 CHC patients, higher VAI score is independently associated with both steatosis and necroinflammatory activity and has a direct correlation with viral load... 
Hepatic steatosis and insulin resistance are associated with severe fibrosis in patients with chronic hepatitis caused by HBV or HCV infectionSalvatore Petta
Sezione di Gastroenterologia, University of Palermo, Palermo, Italy
Liver Int 31:507-15. 2011..We aimed to assess the prevalence and the factors related to steatosis and IR in CHB patients, compared with CHC subjects, and to evaluate the potential association between these features and fibrosis severity...- Retinol-binding protein 4: a new marker of virus-induced steatosis in patients infected with hepatitis c virus genotype 1Salvatore Petta
Cattedra ed Unità Operativa di Gastroenterologia, University of Palermo, Palermo, Italy
Hepatology 48:28-37. 2008..095; 95% confidence interval, 1.007 to 1.192; P = 0.03). CONCLUSION: In nondiabetic, nonobese patients with genotype 1 CHC, serum RBP4 levels might be the expression of a virus-linked pathway to steatosis, largely unrelated to IR... - Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis CSalvatore Petta
Cattedra ed Unità Operativa di Gastroenterologia, DiBiMIS, University of Palermo, Italy
Hepatology 51:1158-67. 2010..Conclusion: G1 CHC patients had low 25(OH)D serum levels, possibly because of reduced CYP27A1 expression. Low vitamin D is linked to severe fibrosis and low SVR on interferon (IFN)-based therapy... - Retreatment with pegylated interferon plus ribavirin of chronic hepatitis C non-responders to interferon plus ribavirin: a meta-analysisCalogero Cammà
Cattedra di Gastroenterologia, Dipartimento Biomedico di Medicina Interna e Specialistica, University of Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy
J Hepatol 51:675-81. 2009..We aimed to focus on SVR rates and to identify factors influencing them in this meta-analysis... - When and how to treat acute hepatitis C?Anna Licata
Cattedra di Gastroenterologia, Istituto di Clinica Medica I, University of Palermo, Piazza delle Cliniche, 2, 90127 Palermo, Italy
J Hepatol 39:1056-62. 2003..Appropriate treatment of acute hepatitis C is still a matter of controversy due to the lack of large controlled trials... - IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver diseaseSalvatore Petta
Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Italy
J Hepatol 56:1356-62. 2012..The main outcomes of the study were to assess whether IL28B rs12979860 and rs8099917 polymorphisms, together with PNPLA3 rs738409 C>G polymorphism, are associated with lobular inflammation and fibrosis, in NAFLD patients... - Insulin resistance is a risk factor for esophageal varices in hepatitis C virus cirrhosisCalogero Cammà
Cattedra and Unità Operativa di Gastroenterologia, Di Bi M I S, University of Palermo, Italy
Hepatology 49:195-203. 2009.... - High liver RBP4 protein content is associated with histological features in patients with genotype 1 chronic hepatitis C and with nonalcoholic steatohepatitisSalvatore Petta
Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Italy
Dig Liver Dis 43:404-10. 2011..To investigate the hepatic expression of retinol-binding protein-4 (RBP4) in chronic hepatitis C (CHC) and nonalcoholic steatohepatitis (NASH) patients, and its association with biochemical and histological patterns of liver damage... - Vitamin D levels and IL28B polymorphisms are related to rapid virological response to standard of care in genotype 1 chronic hepatitis CSalvatore Petta
Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
Antivir Ther 17:823-31. 2012..We assessed whether 25-hydroxyvitamin D (25[OH]D) serum levels are linked to RVR and can be used together with IL28B to construct a pretreatment model to predict RVR... - Does chemotherapy prevent HCV-related hepatocellular carcinoma? ConsAntonio Craxi
Cattedra di Gastroenterologia, DiBiMIS, University of Palermo, Italy
Dig Liver Dis 42:S287-92. 2010..Further large-scale multicenter randomized controlled trials may prove useful to evaluate the benefit on overall survival... - A meta-analysis of survival rates of untreated patients in randomized clinical trials of hepatocellular carcinomaGiuseppe Cabibbo
Cattedra di Gastroenterologia, DiBiMIS, University of Palermo, Italy
Hepatology 51:1274-83. 2010..Conclusion: This meta-analysis confirms the heterogeneity of behavior of untreated HCC and provides a sound basis for stratifying patients with HCC according to expected survival in future trials of new anti-cancer agents... - Prevention of hepatocellular carcinomaAntonio Craxi
Cattedra di Gastroenterologia, University of Palermo, Clinica Medica I, Piazza della Cliniche 2, 90127, Italy
Clin Liver Dis 9:329-46, viii. 2005.... - Fecal calprotectin in clinical practice: a noninvasive screening tool for patients with chronic diarrheaAnna Licata
Sezione e U O C di Gastroenterologia, Di Bi M I S, Universita di Palermo, Palermo, Italy
J Clin Gastroenterol 46:504-8. 2012..Fecal calprotectin (FC) can be easily measured in the stool, being released by leukocytes in inflammatory conditions... - Causes of and prevention strategies for hepatocellular carcinomaGiuseppe Cabibbo
Sezione di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
Semin Oncol 39:374-83. 2012..The pooling of data from the literature suggests a slight preventive effect of antiviral therapy on HCC development in patients with HCV-related cirrhosis, but the preventive effect is limited to sustained virological responders... 
Hyperferritinemia is a risk factor for steatosis in chronic liver diseaseAnna Licata
Gastroenterology and Hepatology Unit, Department of Internal Medicine, University of Palermo, 90127 Palermo, Italy
World J Gastroenterol 15:2132-8. 2009..To investigate the relationship between ferritin and steatosis in patients with chronically abnormal liver function tests (LFTs) and high ferritin level...- Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathwayDanilo Di Bona
Cattedra e Unità Operativa di Gastroenterologia, Dipartimento Biomedico e di Medicina Specialistica, University of Palermo, Palermo, Italy
J Hepatol 45:271-9. 2006.... - Cost-effectiveness of boceprevir or telaprevir for untreated patients with genotype 1 chronic hepatitis CCalogero Cammà
Sezione di Gastroenterologia, Di Bi M I S, University of Palermo, Italy
Hepatology 56:850-60. 2012..Multiple strategies to reduce costs and improve effectiveness include RVR or genotype-guided treatment... - Natural history of untreatable hepatocellular carcinoma: A retrospective cohort studyGiuseppe Cabibbo
Giuseppe Cabibbo, Marcello Maida, Chiara Genco, Pietro Parisi, Marco Peralta, Michela Antonucci, Giuseppe Brancatelli, Calogero Cammà, Antonio Craxì, Vito Di Marco, Section of Gastroenterology, Department of Internal Medicine and Biomedical Specialist, University of Palermo, Palermo 90127, Italy
World J Hepatol 4:256-61. 2012..To investigate the clinical course of untreatable hepatocellular carcinoma (HCC) identified at any stage and to identify factors associated with mortality... - Transarterial chemoembolization for unresectable hepatocellular carcinoma: meta-analysis of randomized controlled trialsCalogero Cammà
National Council of Research, Istituto Metodologie Diagnostiche Avanzate, Palermo, Italy
Radiology 224:47-54. 2002..To review the available evidence of chemoembolization for unresectable hepatocellular carcinoma (HCC)... - Interferon-alpha for HBeAg-positive chronic hepatitis BAntonio Craxi
Cattedra di Gastroenterologia, Istituto di Clinica Medica 1, University of Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy
J Hepatol 39:S99-105. 2003 - Hyperuricaemia: another metabolic feature affecting the severity of chronic hepatitis because of HCV infectionSalvatore Petta
Cattedra di Gastroenterologia, DiBiMIS, University of Palermo, Palermo, Italy
Liver Int 32:1443-50. 2012..Several works observed a link between uric acid serum levels and clinical and histological features of nonalcoholic fatty liver disease. An association between chronic hepatitis C (CHC) and uric acid levels has been poorly investigated... - Meta-analysis of the placebo rates of clinical relapse and severe endoscopic recurrence in postoperative Crohn's diseaseSara Renna
Dipartimento di Medicina, Pneumologia e Fisiologia della Nutrizione Umana, Universita di Palermo, Palermo, Italy
Gastroenterology 135:1500-9. 2008..The aim of this meta-analysis was to focus on knowledge of the placebo rates of relapse and recurrence in postoperative CD and to identify factors influencing these rates... - Genetic predisposition to thrombophilia in inflammatory bowel diseaseMaria Cappello
Sezione e U O C di Gastroenterologia, Palermo, Italy
J Clin Gastroenterol 45:e25-9. 2011..Inflammatory bowel disease (IBD) is linked to a definite risk of thromboembolic events (TE), but data on the role of prothrombotic genetic mutations are conflicting... - Treatment options in HBVAntonio Craxi
Clinica Medica I, Cattedra di Gastroenterologia, University of Palermo, Piazza delle Cliniche 2, 90127 Palermo, Italy
J Hepatol 44:S77-83. 2006..Adefovir, excluding cost, is preferable to lamivudine as a first-choice because there is less chance of inducing resistance. The long-term benefit of lamivudine and adefovir and the role of combinations is under investigation... - Systematic review by meta-analyses on the possible role of TNF-alpha polymorphisms in association with Alzheimer's diseaseDanilo Di Bona
Dipartimento di Biopatologia e Metodologie Biomediche, University of Palermo, Italy
Brain Res Rev 61:60-8. 2009..Current findings support an association between -850 C>T polymorphism and the risk of developing AD; hence, they strengthen the suggestion of a potential role for anti-TNF therapy to maintain physiologic levels of TNF-alpha...