Eusebio Chiefari

Summary

Country: Italy

Publications

  1. ncbi request reprint Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
    Daniela Foti
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università di Catanzaro Magna Graecia, Via T Campanella 115, 88100 Catanzaro, Italy
    Nat Med 11:765-73. 2005
  2. pmc The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis
    Eusebio Chiefari
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Catanzaro, Italy
    BMC Biol 7:24. 2009
  3. doi request reprint Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes
    Eusebio Chiefari
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università di Catanzaro Magna Græcia, Viale Europa Loc Germaneto, Catanzaro 88100, Italy
    Nat Commun 1:40. 2010
  4. ncbi request reprint Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer
    Francesco Paonessa
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università di Catanzaro Magna Graecia, Catanzaro, Italy
    Cancer Res 66:5085-93. 2006
  5. pmc Transcriptional regulation of the HMGA1 gene by octamer-binding proteins Oct-1 and Oct-2
    Eusebio Chiefari
    Department of Health Sciences, University Magna Græcia of Catanzaro, Viale Europa Loc Germaneto, Catanzaro, Italy
    PLoS ONE 8:e83969. 2013
  6. pmc A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription
    Daniela Foti
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università degli Studi di Catanzaro Magna Graecia, 88100 Catanzaro, Italy
    Mol Cell Biol 23:2720-32. 2003

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
    Daniela Foti
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università di Catanzaro Magna Graecia, Via T Campanella 115, 88100 Catanzaro, Italy
    Nat Med 11:765-73. 2005
    ....
  2. pmc The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis
    Eusebio Chiefari
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Catanzaro, Italy
    BMC Biol 7:24. 2009
    ..Also, the hypothesis that increased insulin sensitivity in Hmga1-deficient mice could be related to the deficit of an insulin resistance factor is discussed...
  3. doi request reprint Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes
    Eusebio Chiefari
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università di Catanzaro Magna Græcia, Viale Europa Loc Germaneto, Catanzaro 88100, Italy
    Nat Commun 1:40. 2010
    ..These data provide evidence for a regulatory role of an expressed pseudogene in humans and establishes a novel mechanistic linkage between pseudogene HMGA1-p expression and type 2 diabetes mellitus...
  4. ncbi request reprint Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer
    Francesco Paonessa
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università di Catanzaro Magna Graecia, Catanzaro, Italy
    Cancer Res 66:5085-93. 2006
    ..Our findings support this hypothesis and suggest that in affected individuals, hyperactivation of the AP-2 gene through the overexpression of IR may play a key role in breast carcinogenesis...
  5. pmc Transcriptional regulation of the HMGA1 gene by octamer-binding proteins Oct-1 and Oct-2
    Eusebio Chiefari
    Department of Health Sciences, University Magna Græcia of Catanzaro, Viale Europa Loc Germaneto, Catanzaro, Italy
    PLoS ONE 8:e83969. 2013
    ..Furthermore, they consistently support the hypothesis that a putative defect in Oct-1 and/or Oct-2, by affecting HMGA1 expression, may cause INSR dysfunction, leading to defects of the INSR signaling pathway. ..
  6. pmc A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription
    Daniela Foti
    Dipartimento di Medicina Sperimentale e Clinica G Salvatore, Università degli Studi di Catanzaro Magna Graecia, 88100 Catanzaro, Italy
    Mol Cell Biol 23:2720-32. 2003
    ....