Research Topics
Species | Giancarlo MarenziSummaryAffiliation: Centro Cardiologico Monzino Country: Italy Publications
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Publications
Contrast-induced nephropathyGiancarlo Marenzi
Department of Cardiovascular Sciences, Centro Cardiologico Monzino, I R C C S, University of Milan, Via Parea 4, 20138, Milan, Italy
Intern Emerg Med 7:181-3. 2012..The purpose of this study is to examine the pathophysiology, risk factors and clinical course of CIN, as well as the most recent studies dealing with its prevention and potential therapeutic interventions, especially during PCI...
Prevention of contrast nephropathy by furosemide with matched hydration: the MYTHOS (Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy Prevention) trialGiancarlo Marenzi
Centro Cardiologico Monzino, IRCCS, Department of Cardiovascular Sciences, University of Milan, Milan, Italy
JACC Cardiovasc Interv 5:90-7. 2012..This study investigated the effect of furosemide-forced diuresis and intravenous saline infusion matched with urine output, using a novel dedicated device designed for contrast-induced nephropathy (CIN) prevention...
Recent advances in the prevention of radiocontrast-induced nephropathyGiancarlo Marenzi
Centro Cardiologico Monzino, IRCCS Institute of Cardiology of the University of Milan, Milan, Italy
Curr Opin Crit Care 10:505-9. 2004..This article reviews recent clinical researches concerning new developments in the prevention of radiocontrast nephropathy and analyzes unresolved issues...
Can contrast-induced nephropathy after percutaneous coronary intervention be accurately predicted with a risk score?Giancarlo Marenzi
Intensive Cardiac Care Unit, Centro Cardiologico Monzino, Institute of Cardiology, University of Milan, Milan, Italy
Nat Clin Pract Cardiovasc Med 2:80-1. 2005
Comparison of two hemofiltration protocols for prevention of contrast-induced nephropathy in high-risk patientsGiancarlo Marenzi
Centro Cardiologico Monzino, I R C C S, Institute of Cardiology of the University of Milan, Milan, Italy
Am J Med 119:155-62. 2006..We assessed the mechanisms involved in the prophylactic effect of hemofiltration and of the most effective hemofiltration protocol to prevent contrast-induced nephropathy in patients with chronic kidney disease...
Prophylactic hemodialysis for the prevention of contrast-induced nephropathy after coronary angiographyGiancarlo Marenzi
Intensive Cardiac Care Unit at the Centro Cardiologico Monzino, Istituti di Ricovero e Cura a Carattere Scientifico, Institute of Cardiology, University of Milan, Milan, Italy
Nat Clin Pract Nephrol 4:130-1. 2008
N-acetylcysteine and contrast-induced nephropathy in primary angioplastyGiancarlo Marenzi
Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Institute of Cardiology, University of Milan, Milan, Italy
N Engl J Med 354:2773-82. 2006..We investigated the antioxidant N-acetylcysteine for the prevention of contrast-medium-induced nephropathy in patients undergoing primary angioplasty...
[Management of renal complications during primary angioplasty]Giancarlo Marenzi
Centro Cardiologico Monzino, I R C C S, Istituto di Cardiologia, Universita, Milano
Recenti Prog Med 98:367-72. 2007....
Acute kidney injury in ST-segment elevation acute myocardial infarction complicated by cardiogenic shock at admissionGiancarlo Marenzi
Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Institute of Cardiology of the University of Milan, Milan, Italy
Crit Care Med 38:438-44. 2010..To evaluate the clinical and prognostic relevance of acute kidney injury (AKI) in the setting of ST-elevation acute myocardial infarction (STEMI) complicated by cardiogenic shock (CS)...
Impact of cardiac and renal dysfunction on inhospital morbidity and mortality of patients with acute myocardial infarction undergoing primary angioplastyGiancarlo Marenzi
Centro Cardiologico Monzino, I R C C S, Institute of Cardiology, University of Milan, Milan, Italy
Am Heart J 153:755-62. 2007....
Contrast volume during primary percutaneous coronary intervention and subsequent contrast-induced nephropathy and mortalityGiancarlo Marenzi
University of Milan, Milan, Italy
Ann Intern Med 150:170-7. 2009....
Hemofiltration in heart failureG Marenzi
Centro Cardiologico Monzino, IRCCS, Institute of Cardiology, University of Milan, Milan, Italy
Int J Artif Organs 27:1070-6. 2004..In this setting, hemofiltration, differently from diuretics, is able to remove the increased lung water content and to improve clinical condition, exercise capacity and lung function...
Circulating cytochrome c as potential biomarker of impaired reperfusion in ST-segment elevation acute myocardial infarctionGiancarlo Marenzi
Centro Cardiologico Monzino, IRCCS, Department of Cardiovascular Sciences, University of Milan, Milan, Italy
Am J Cardiol 106:1443-9. 2010..20 to 2.20, vs 1.1 ng/ml, interquartile range 0.65 to 1.55; p = 0.04). In conclusion, serum cytochrome c is detectable in the early phase of STEMI treated with pPCI and is associated with clinical signs of impaired myocardial reperfusion...
Contrast-induced nephropathy in patients undergoing primary angioplasty for acute myocardial infarctionGiancarlo Marenzi
Centro Cardiologico Monzino, I R C C S, Institute of Cardiology of the University of Milan, Milan, Italy
J Am Coll Cardiol 44:1780-5. 2004..The aim of this research was to assess the incidence, clinical predictors, and outcome of contrast-induced nephropathy (CIN) after primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI)...
Hemofiltration in the prevention of radiocontrast agent induced nephropathyG Marenzi
Monzino Heart Center, IRCCS, Institute of Cardiology, University of Milan, Milan, Italy
Minerva Anestesiol 70:189-91. 2004..The aim of the study was to investigate the role of hemofiltration in preventing contrast nephropathy in patients with renal failure...
Acute hyperglycemia and contrast-induced nephropathy in primary percutaneous coronary interventionGiancarlo Marenzi
Department of Cardiovascular Sciences, Centro Cardiologico Monzino, I R C C S, University of Milan, Milan, Italy
Am Heart J 160:1170-7. 2010..We investigated the possible association between acute hyperglycemia and CIN in patients undergoing primary PCI...
[Prevention of contrast-induced nephropathy and management of high-risk patients]Giancarlo Marenzi
Centro Cardiologico Monzino, IRCCS, Istituto di Cardiologia, Universita degli Studi, Milano
G Ital Cardiol (Rome) 10:88-96. 2009....
The prevention of radiocontrast-agent-induced nephropathy by hemofiltrationGiancarlo Marenzi
Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico, Institute of Cardiology, University of Milan, Milan, Italy
N Engl J Med 349:1333-40. 2003..We investigated the role of hemofiltration, as compared with isotonic-saline hydration, in preventing contrast-agent-induced nephropathy in patients with renal failure...
Serum to urinary sodium concentration ratio is an estimate of plasma renin activity in congestive heart failureGiancarlo Marenzi
Centro Cardiologico Monzino, IRCCS, Institute of Cardiology, University of Milan, Via Parea 4, 20138 Milan, Italy
Eur J Heart Fail 4:597-603. 2002..In CHF, the [sNa(+)]/[uNa(+)] ratio best correlates with PRA and reflects the basal activity as well as the rapid changes (as those induced by UF) of the RAS. Therefore, it can be considered a strong and easily available marker of PRA...
Continuous veno-venous hemofiltration for the treatment of contrast-induced acute renal failure after percutaneous coronary interventionsGiancarlo Marenzi
Centro Cardiologico Monzino, IRCCS, Institute of Cardiology, University of Milan, Milan, Italy
Catheter Cardiovasc Interv 58:59-64. 2003..However, despite promising early results, large randomized trials are required to define the role of CVVH in ARF after PCI...
Kinetics of plasma SPB and RAGE during mechanical ventilation in patients undergoing major vascular surgeryPiergiuseppe Agostoni
Centro Cardiologico Monzino, IRCCS, Milan, Italy
Respir Physiol Neurobiol 178:256-60. 2011..SPB(N) increase (T(END)-T0), but not RAGE(N), was related to ΔPaO(2)/FiO2 changes during mechanical ventilation (r=0.575, p=0.01). Plasma RAGE(N) and SPB(N) kinetics in patients undergoing major vascular surgery are different...
Hyperoxemic perfusion of the left anterior descending coronary artery after primary angioplasty in anterior ST-elevation myocardial infarctionDaniela Trabattoni
Centro Cardiologico Monzino IRCCS, Institute of Cardiology, University of Milan, Milan, Italy
Catheter Cardiovasc Interv 67:859-65. 2006..Enzyme kinetic and ST-segment changes suggest faster and more complete microvascular reperfusion and may explain the salutary effects of this new therapy on left ventricular function...
N-acetylcysteine for prevention of acute renal failure in patients with chronic renal insufficiency undergoing cardiac surgery: a prospective, randomized, clinical trialErminio Sisillo
Anesthesia and Critical Care Unit, Centro Cardiologico Monzino, I R C C S, Institute of Cardiology, University of Milan, Milan, Italy
Crit Care Med 36:81-6. 2008..To assess the preventive effect of the antioxidant N-acetylcysteine on postoperative acute renal failure in patients with renal insufficiency undergoing cardiac surgery...
Gas diffusion and alveolar-capillary unit in chronic heart failurePiergiuseppe Agostoni
Centro Cardiologico Monzino, IRCCS, Istituto di Cardiologia, Universita di Milano, Via Parea 4, 20138 Milan, Italy
Eur Heart J 27:2538-43. 2006..Diffusion depends on membrane diffusion (DM) and the amount of blood participating in gas exchange (VC). How DM, VC, and the alveolar-capillary unit behave in relationship to CHF severity is unknown...
Gene expression profiling reveals multiple differences in platelets from patients with stable angina or non-ST elevation acute coronary syndromeGualtiero Colombo
Centro Cardiologico Monzino IRCCS, Via Parea 4, Milan, Italy
Thromb Res 128:161-8. 2011....
Circulating Levels of Dimethylarginines, Chronic Kidney Disease and Long-Term Clinical Outcome in Non-ST-Elevation Myocardial InfarctionViviana Cavalca
Centro Cardiologico Monzino, I R C C S, Milan, Italy Dipartimento di Scienze Cliniche e di Comunità, Universita degli Studi di Milano, Milan, Italy
PLoS ONE 7:e48499. 2012..We measured plasma concentration of arginine, ADMA and SDMA and investigated their relationship with CKD and long-term outcome in non-ST-elevation myocardial infarction (NSTEMI)...
Percutaneous cardiopulmonary support for catheter ablation of unstable ventricular arrhythmias in high-risk patientsCorrado Carbucicchio
Centro Cardiologico, Fondazione Monzino IRCCS, Institute of Cardiology, University of Milan, Milano, Italy
Herz 34:545-52. 2009..The use of the percutaneous cardiopulmonary support (CPS) for circulatory assistance may allow patient's stabilization and enhance efficacy and safety of CA in this emergency setting...
Surfactant protein B and RAGE increases in the plasma during cardiopulmonary bypass: a pilot studyP Agostoni
Centro Cardiologico Monzino, IRCCS, Dept of Cardiovascular Sciences, University of Milan, Milan, Italy
Eur Respir J 37:841-7. 2011..This behaviour was confirmed when RAGE and SPB were normalised for protein content. Parallel changes were observed for immature SPB. Plasma RAGE and SPBs are sensitive and rapid markers of lung distress...
High-sensitivity C-reactive protein is within normal levels at the very onset of first ST-segment elevation acute myocardial infarction in 41% of cases: a multiethnic case-control studyNicole Cristell
Universita Vita Salute San Raffaele, Istituto Scientifico San Raffaele, Milan, Italy
J Am Coll Cardiol 58:2654-61. 2011..This study sought to assess the prevalence of normal levels of high sensitivity C-reactive protein (hsCRP) at the very onset of ST-segment elevation myocardial infarction (STEMI)...
Proteome of platelets in patients with coronary artery diseaseCristina Banfi
Centro Cardiologico Monzino, I R C C S, Milan, Italy
Exp Hematol 38:341-50. 2010..This study aimed at investigating the protein patterns of platelets from patients with stable or acute coronary atherosclerosis (CAD), in which platelets play a key role...
Tissue factor in patients with acute coronary syndromes: expression in platelets, leukocytes, and platelet-leukocyte aggregatesMarta Brambilla
Department of Pharmacological Sciences, University of Milan, Via Balzaretti, 9, 20133 Milan, Italy
Arterioscler Thromb Vasc Biol 28:947-53. 2008..The aim of this study was to investigate the expression of TF in PLA, in platelets, and in monocytes of acute coronary syndrome (ACS) patients compared to SA patients and healthy subjects (Controls)...
Circadian distribution of acute myocardial infarction by anatomic location and coronary artery involvementPaolo Moruzzi
Centro Cardiologico Monzino, I R C C S, Institute of Cardiology, University of Milan, Milan, Italy
Am J Med 116:24-7. 2004..Acute myocardial infarction follows a circadian pattern, with a morning peak ascribed to sympathetic activation. However, about 20% of myocardial infarctions occur between midnight and 6 AM; these events may have different characteristics...
Pulmonary hemodynamic and tidal volume changes during exercise in heart failurePiergiuseppe Agostoni
Institute of Cardiology, Centro Cardiologico Monzino, IRCCS, University of Milan, Centro di Studio per le Ricerche Cardiovascolari del Consiglio Nazionale delle Ricerche, Milan, Italy
Ital Heart J 3:104-8. 2002....
Contrast-induced nephropathyAntonio L Bartorelli
Centro Cardiologico Monzino IRCCS, Institute of Cardiology, University of Milan, Milan, Italy
J Interv Cardiol 21:74-85. 2008..The purpose of this article is to examine the pathophysiology, risk factors, and clinical course of CIN, as well as the most recent studies dealing with its prevention and potential therapeutic interventions, especially during PCI...
Circulating microRNAs are new and sensitive biomarkers of myocardial infarctionYuri D'Alessandra
Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS, Milan, Italy
Eur Heart J 31:2765-73. 2010..Circulating microRNAs (miRNAs) may represent a novel class of biomarkers; therefore, we examined whether acute myocardial infarction (MI) modulates miRNAs plasma levels in humans and mice...
Cardiac and renal dysfunction in chronic heart failure: relation to neurohumoral activation and prognosisG Marenzi
IRCCS, Institute of Cardiology, University of Milan, Italy
Am J Med Sci 321:359-66. 2001..We investigated the relationship between both cardiac and renal dysfunction and neurohumoral activation, and their possible influence on prognosis...
Circulatory response to fluid overload removal by extracorporeal ultrafiltration in refractory congestive heart failureG Marenzi
Centro Cardiologico Monzino, I R C C S, Institute of Cardiology, University of Milan, Milan, Italy
J Am Coll Cardiol 38:963-8. 2001..The goal of this study was to investigate the hemodynamic and circulatory adjustments to extracorporeal ultrafiltration (UF) in refractory congestive heart failure (rCHF)...
Lack of improvement of lung diffusing capacity following fluid withdrawal by ultrafiltration in chronic heart failureP G Agostoni
Istituto di Cardiologia dell Universita degli Studi, Centro Cardiologico IRCCS, Centro di Studio per le Ricerche Cardiovascolari del CNR, Milan, Italy
J Am Coll Cardiol 36:1600-4. 2000..We sought to investigate the possibility that lung diffusing capacity reduction observed in chronic heart failure is reversible in the short term...
[Extracorporeal treatment in patients with heart failure: pathophysiology, indications and results.]G Marenzi
Centro Cardiologico Monzino, I.R.C.C.S, Istituto di Cardiologia, , Milano
G Ital Nefrol 23:S46-51. 2006..In this setting, ultrafiltration, unlike diuretics, can remove the increased lung water content and improve clinical condition, exercise capacity and lung function...
Noninvasive measurement of cardiac output during exercise by inert gas rebreathing technique: a new tool for heart failure evaluationPiergiuseppe Agostoni
J Am Coll Cardiol 46:1779-81. 2005
Improved clinical outcome after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trialGiancarlo Marenzi
Eur Heart J 28:2172-3; author reply 2173-4. 2007
