S Ciatto

Summary

Affiliation: Centro per lo Studio e la Prevenzione Oncologica
Country: Italy

Publications

  1. ncbi Persistent human papilloma virus infection as an indicator of risk of recurrence of high-grade cervical intraepithelial neoplasia treated by the loop electrosurgical excision procedure
    Silvia Cecchini
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 90:225-8. 2004
  2. doi Magnetic resonance imaging screening of the contralateral breast in women with newly diagnosed breast cancer: systematic review and meta-analysis of incremental cancer detection and impact on surgical management
    Meagan Elizabeth Brennan
    Screening and Test Evaluation Program, School of Public Health, Faculty of Medicine, and National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney, Australia
    J Clin Oncol 27:5640-9. 2009
  3. ncbi Specific features of the Italian section of the ERSPC
    S Ciatto
    Centro per lo Studio e lo Prevenzione Oncologica, Firenze, Italy
    BJU Int 92:30-2. 2003
  4. ncbi Comparison of standard reading and computer aided detection (CAD) on a national proficiency test of screening mammography
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, I 50131 Florence, Italy
    Eur J Radiol 45:135-8. 2003
  5. ncbi Determining overdiagnosis by screening with DRE/TRUS or PSA (Florence pilot studies, 1991-1994)
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Florence, Italy
    Eur J Cancer 41:411-5. 2005
  6. ncbi Determining the sensitivity of transrectal ultrasonography on a consecutive series of prostate cancers in a clinical and screening setting
    Stefano Ciatto
    Tumori 88:281-3. 2002
  7. ncbi Role of multimedial diagnosis of breast cancer in women below 36 year of age
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Radiol Med 109:321-9. 2005
  8. ncbi Transperineal sonography guided biopsy of the prostate: critical review of 1107 cases
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Radiol Med 103:219-24. 2002
  9. ncbi Second reading of screening mammograms increases cancer detection and recall rates. Results in the Florence screening programme
    S Ciatto
    Department of Diagnostic Imaging, Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Florence, Italy
    J Med Screen 12:103-6. 2005
  10. ncbi Reader variability in reporting breast imaging according to BI-RADS assessment categories (the Florence experience)
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Breast 15:44-51. 2006

Collaborators

Detail Information

Publications124 found, 100 shown here

  1. ncbi Persistent human papilloma virus infection as an indicator of risk of recurrence of high-grade cervical intraepithelial neoplasia treated by the loop electrosurgical excision procedure
    Silvia Cecchini
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 90:225-8. 2004
    ..To evaluate the recurrence rate of high-grade cervical intraepithelial neoplasia (CIN) treated by the loop electrosurgical excision procedure (LEEP) according to the persistence of human papilloma virus (HPV) infection...
  2. doi Magnetic resonance imaging screening of the contralateral breast in women with newly diagnosed breast cancer: systematic review and meta-analysis of incremental cancer detection and impact on surgical management
    Meagan Elizabeth Brennan
    Screening and Test Evaluation Program, School of Public Health, Faculty of Medicine, and National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney, Australia
    J Clin Oncol 27:5640-9. 2009
    ..This article is a review and meta-analysis of studies reporting contralateral MRI in women with newly diagnosed invasive breast cancer...
  3. ncbi Specific features of the Italian section of the ERSPC
    S Ciatto
    Centro per lo Studio e lo Prevenzione Oncologica, Firenze, Italy
    BJU Int 92:30-2. 2003
  4. ncbi Comparison of standard reading and computer aided detection (CAD) on a national proficiency test of screening mammography
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, I 50131 Florence, Italy
    Eur J Radiol 45:135-8. 2003
    ..To evaluate the role of computer aided detection (CAD) in improving the interpretation of screening mammograms..
  5. ncbi Determining overdiagnosis by screening with DRE/TRUS or PSA (Florence pilot studies, 1991-1994)
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Florence, Italy
    Eur J Cancer 41:411-5. 2005
    ..23 in subjects excluded from invitation due to previous cancer or major illness (95%CI=0.8-1.5). A 66% excess incidence rate was observed in the screened subjects over a 9-year period, confirming previous estimates of overdiagnosis...
  6. ncbi Determining the sensitivity of transrectal ultrasonography on a consecutive series of prostate cancers in a clinical and screening setting
    Stefano Ciatto
    Tumori 88:281-3. 2002
    ..To evaluate the sensitivity at transrectal ultrasonography (TRUS) for prostate cancer...
  7. ncbi Role of multimedial diagnosis of breast cancer in women below 36 year of age
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Radiol Med 109:321-9. 2005
    ..To evaluate the sensitivity for breast cancer of different diagnostic tests performed in a consecutive series of women aged under 36 years...
  8. ncbi Transperineal sonography guided biopsy of the prostate: critical review of 1107 cases
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Radiol Med 103:219-24. 2002
    ..To assess the predictive value for a positive biopsy of different indicators (rectal examination, transrectal ultrasonography, total PSA, PSA density)...
  9. ncbi Second reading of screening mammograms increases cancer detection and recall rates. Results in the Florence screening programme
    S Ciatto
    Department of Diagnostic Imaging, Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Florence, Italy
    J Med Screen 12:103-6. 2005
    ..To assess double reading effectiveness in mammography screening...
  10. ncbi Reader variability in reporting breast imaging according to BI-RADS assessment categories (the Florence experience)
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Breast 15:44-51. 2006
    ..Although training may improve these results, simpler alternative reporting methods (systems), focused on clinical decision-making, should be explored...
  11. ncbi Categorizing breast mammographic density: intra- and interobserver reproducibility of BI-RADS density categories
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, I 50131 Firenze, Italy Screening and Test Evaluation Programme, School of Public Health, University of Sydney, Australia
    Breast 14:269-75. 2005
    ..As inconsistency is probably due to erroneous perception of classification criteria, standard sets of reference images should be made available for training...
  12. ncbi The role of arbitration of discordant reports at double reading of screening mammograms
    S Ciatto
    Radiologist and Head of Unit, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    J Med Screen 12:125-7. 2005
    ..To asses the effectiveness of arbitration of discordant double readings in mammography screening...
  13. ncbi Association of endometrial thickness assessed at trans-vaginal ultrasonography to endometrial cancer in postmenopausal women asymptomatic or with abnormal uterine bleeding
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Ferrara, Italy
    Radiol Med 104:437-42. 2002
    ..To define the normal cut off of endometrial thickness as measured at transvaginal ultrasonography (TVUS) in order to define postmenopausal women without symptoms or with abnormal uterine bleeding (AUB) at risk of endometrial carcinoma (EC)...
  14. ncbi Free to total PSA ratio is not a reliable predictor of prostate biopsy outcome
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 90:324-7. 2004
    ..The aim of this study was to assess the validity of predictors of prostate biopsy outcome in order to improve their positive predictive value...
  15. pmc Surveillance for endometrial cancer with transvaginal ultrasonography of breast cancer patients under tamoxifen treatment
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Br J Cancer 88:1175-9. 2003
    ..100, 81.6 or 91.6%; spec.=22.8, 40.4, or 56.7%). Breast cancer patients under tamoxifen might be selected for further invasive assessment on the basis of AUB and endometrial thickness assessed at TVUS...
  16. pmc Breast density as a determinant of interval cancer at mammographic screening
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale Volta 171, 50131 Firenze, Italy
    Br J Cancer 90:393-6. 2004
    ..Special screening protocols (shorter rescreening interval, routine use of ultrasonography) might be suggested for these subjects in order to improve screening sensitivity and efficacy...
  17. ncbi The ERSPC Quality Control Committee
    S Ciatto
    Department of Diagnostic Medical Imaging, CSPO, Firenze, Italy
    BJU Int 92:57-61. 2003
  18. pmc Comparison of standard and double reading and computer-aided detection (CAD) of interval cancers at prior negative screening mammograms: blind review
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, I 50131 Florence, Italy
    Br J Cancer 89:1645-9. 2003
    ..9%. The use of CAD as a possible surrogate to conventional DOUBLE needs to be confirmed by further studies, which should include a cost-effective analysis...
  19. ncbi How to improve the specificity and sensitivity of biopsy technique in screening
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    BJU Int 92:79-83. 2003
  20. ncbi Contamination by opportunistic screening in the European Randomized Study of Prostate Cancer Screening
    S Ciatto
    Department Diagnostic Medical Imaging, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    BJU Int 92:97-100. 2003
  21. ncbi Comparison of standard reading and computer aided diagnosis (CAD) on a proficiency test of screening mammography
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Radiol Med 106:59-65. 2003
    ..To evaluate the role of computer aided diagnosis (CAD) to improve screening mammograms interpretation...
  22. ncbi A methodology to evaluate differential costs of full field digital as compared to conventional screen film mammography in a clinical setting
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A, Volta 171, Florence, Italy
    Eur J Radiol 57:69-75. 2006
    ..The present study, performed at the Centro per lo Studio e la Prevenzione Oncologica of Florence, using both FFDM and SFM, was aimed at estimating the impact of introducing the new FFDM technique on overall mammography costs...
  23. ncbi Comparison of two commercial systems for computer-assisted detection (CAD) as an aid to interpreting screening mammograms
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Radiol Med 107:480-8. 2004
    ..To compare the diagnostic accuracy of two commercial CAD systems (CADx and R2) and their impact as an aid to conventional reading of screening mammograms...
  24. ncbi Prognostic impact of the early detection of metachronous contralateral breast cancer
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Florence, Italy
    Eur J Cancer 40:1496-501. 2004
    ..Although length bias may have occurred (symptomatic MCBC had a shorter free interval from the first cancer), the present evidence supports the practice of active follow-up aimed at the early detection of asymptomatic MCBC...
  25. ncbi Computer-aided detection (CAD) of cancers detected on double reading by one reader only
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131, Florence, Italy
    Breast 15:528-32. 2006
    ..3%) cancers. The average recall rate was 14.2%, the majority of recalls (45 out of 64) occurring for lesions marked by CAD. CAD may help in detecting at most half of cancers missed at a single reading but detected by a second reader...
  26. ncbi Breast imaging and needle biopsy in women with clinically evident breast cancer: does combined imaging change overall diagnostic sensitivity?
    Stefano Ciatto
    Department of Diagnostic Imaging, Centro per lo Studio e la Prevenzione Oncologica CSPO, Viale A Volta 171, 50131 Florence, Italy
    Breast 16:382-6. 2007
    ..1% where combined imaging is included into the diagnostic pathway. This is largely due to needle biopsy identifying most cancers missed on single imaging thus negating the effect of additional imaging on overall sensitivity...
  27. ncbi PSA use and incidence of prostate biopsy in the Tuscany region: is opportunistic screening discounting biopsy in subjects with PSA elevation?
    Stefano Ciatto
    CSPO, Istituto Scientifico per la Prevenzione Oncologica, Florence, Italy
    Tumori 94:518-22. 2008
    ..To assess PSA use in the general population and estimate biopsy rate subsequent to opportunistic screening...
  28. pmc Second breast cancers in a Tuscan case series: characteristics, prognosis, and predictors of survival
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Istituto scientifico della Regione Toscana, Florence, Italy
    Br J Cancer 99:539-44. 2008
    ..Prognosis following a second breast cancer in this cohort was generally good. However, large or node-positive second tumours, and shorter intervals between diagnoses were indicators of poorer survival...
  29. ncbi Current cancer profiles of the Italian regions: should cancer incidence be monitored at a national level?
    Stefano Ciatto
    Department of Diagnostic Imaging, CSPO, Istituto per la Prevenzione Oncologica, Florence, Italy
    Tumori 93:529-31. 2007
  30. ncbi Interval breast cancers in screening: the effect of mammography review method on classification
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 5131, Florence, Italy
    Breast 16:646-52. 2007
    ..Due to expected variability, review methods need standardisation to improve screening quality. Our data support blinded review of IC in mammography screening...
  31. pmc Association of FOBT-assessed faecal Hb content with colonic lesions detected in the Florence screening programme
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale Volta 171, 50131 Firenze, Italy
    Br J Cancer 96:218-21. 2007
    ..7%) and a high positive predictive value (41.5%). Faecal Hb content is significantly higher for those lesions (cancer and high-risk adenomas) screening is aimed at detecting...
  32. ncbi Predictors of random sextant biopsy outcome in screened men with PSA > 4 ng/mL and a negative sextant biopsy at previous screening. Experience in a population-based screening program in Florence
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Int J Biol Markers 19:89-92. 2004
    ..2%) of the benign biopsies while decreasing the sensitivity by 7.6% (1/13), and is thus suggested as a possible criterion for the indication of repeat random biopsy for persistent PSA elevation...
  33. ncbi Analysis of the results of a proficiency test in screening mammography at the CSPO of Florence: review of 705 tests
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, I 50131, Firenze, Italy
    Radiol Med 111:797-803. 2006
    ..The aim of this study was to evaluate the performance of a sample of Italian radiologists undergoing a proficiency test of screening mammography...
  34. ncbi On the clinical usefulness of the free-to-total prostate-specific antigen ratio
    S Ciatto
    Centre for Oncological Study and Prevention, Florence, Italy
    Int J Biol Markers 21:1-5. 2006
    ..7 to 2.6 cancer biopsies would have been delayed to avoid 10 benign biopsies. As this balance is not acceptable, F/T PSA has no role as a biopsy indicator and its clinical use is questionable...
  35. ncbi Prostate cancer specific mortality in the Florence screening pilot study cohort 1992-1993
    Stefano Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Firenze, Italy
    Eur J Cancer 42:1858-62. 2006
    ..99; 95% CI=0.69-1.37). This finding might suggest a screening effect, but might also be ascribed to an healthy screening effect, and cannot be assumed as a reliable evidence of screening efficacy...
  36. ncbi A feasibility study of screening for endometrial carcinoma in postmenopausal women by ultrasonography
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 81:334-7. 1995
    ..Studies of screening for other carcinomas may be considered of higher priority...
  37. ncbi Measuring interval cancers in population-based screening using different assays of fecal occult blood testing: the District of Florence experience
    M Zappa
    Center for the Study and Prevention of Cancer CSPO A O Careggi, Florence, Italy
    Int J Cancer 92:151-4. 2001
    ..The assumption that FOBT screening for CRC has to be based on a guaiac test should be reconsidered, and RPHA should be recommended as the standard FOBT for screening purposes...
  38. pmc Sensitivity of latex agglutination faecal occult blood test in the Florence District population-based colorectal cancer screening programme
    G Castiglione
    Diagnostic Imaging Unit, CSPO, Viale A, Volta 171, Florence 50131, Italy
    Br J Cancer 96:1750-4. 2007
    ..Increasing screening sensitivity might be achieved if the detection rate of advanced adenomas could be increased without unacceptable loss in specificity...
  39. ncbi Comparative analysis of results of guaiac and immunochemical tests for faecal occult blood in colorectal cancer screening in two oncological institutions
    G Castiglione
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Eur J Cancer Prev 3:399-405. 1994
    ..5%), and HOS (96.1%) specificity. No significant difference between tests is evident in the CSPO population as far as positive predictive values and sensitivity for cancer and adenomas are concerned.(ABSTRACT TRUNCATED AT 250 WORDS)..
  40. ncbi Screening for colorectal cancer by faecal occult blood test: comparison of immunochemical tests
    G Castiglione
    Presidio per la Prevenzione Oncologica, Azienda Ospedaliera Careggi, Florence, Italy
    J Med Screen 7:35-7. 2000
    ..To compare two immunochemical faecal occult blood tests based on reversed passive haemagglutination (RPHA) or latex agglutination (Hdia) in a population based screening setting...
  41. pmc Immunochemical vs guaiac faecal occult blood tests in a population-based screening programme for colorectal cancer
    G Castiglione
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Br J Cancer 74:141-4. 1996
    ..Further evaluation of Hemeselect cost-effectiveness and sensitivity is needed in order to assess the optimal threshold of positivity and screening frequency...
  42. ncbi Predicting prostate biopsy outcome by findings at digital rectal examination, transrectal ultrasonography, PSA, PSA density and free-to-total PSA ratio in a population-based screening setting
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Int J Biol Markers 16:179-82. 2001
    ..7-1.8). None of the possible variable combinations was clinically useful: the highest PPV (83.3%) was obtained with a combination of suspicious DRE/TRUS, PSAD >0.20 and F/T <0.15, which nevertheless missed 20 of 52 cancers...
  43. ncbi Analysis of false-negative and underreported smears in the Florence district screening program for cervical carcinoma
    M Confortini
    Centro per lo Studio e la Prevenzione Oncologica, Florence University, Italy
    Tumori 83:880-3. 1997
    ..Due to the rarity of misperceived abnormalities (true screening errors), manual or automated rescreening of negative smears would not be an effective procedure for quality control...
  44. ncbi Effect of faecal occult blood testing on colorectal mortality: results of a population-based case-control study in the district of Florence, Italy
    M Zappa
    Centre for the Study and Prevention of Cancer CSPO, Florence, Italy
    Int J Cancer 73:208-10. 1997
    ..54; 95% CI, 0.3-0.9) and increased towards unity subsequently. Our results suggest that screening for CRC by biennial faecal occult blood testing can reduce mortality from the disease...
  45. ncbi Comparing two modalities of screening for prostate cancer: digital rectal examination + transrectal ultrasonography vs. prostate-specific antigen
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 81:225-9. 1995
    ..PSA seems the ideal test to be used in prospective controlled studies aimed at demonstrating screening efficacy...
  46. ncbi Minority report - false negative breast assessment in women recalled for suspicious screening mammography: imaging and pathological features, and associated delay in diagnosis
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica CSPO, Florence, Italy
    Breast Cancer Res Treat 105:37-43. 2007
    ..We studied imaging, pathology and diagnostic aspects of false negative assessment (FNA) in women recalled for suspicious screening mammography...
  47. ncbi PSA doubling time as a predictor of the outcome of random prostate biopsies prompted by isolated PSA elevation in subjects referred to an outpatient biopsy facility in a routine clinical scenario
    S Ciatto
    Istituto per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Int J Biol Markers 23:187-91. 2008
    ..To assess the validity of PSA doubling time (PSADT) as a predictor of prostate sextant biopsy outcome in patients with PSA levels in the 4-10 ng/mL range...
  48. pmc Immunochemical faecal occult blood test: number of samples and positivity cutoff. What is the best strategy for colorectal cancer screening?
    G Grazzini
    Department of Screening, ISPO Cancer Prevention and Research Institute Florence, Viale Volta 171, Florence, Italy
    Br J Cancer 100:259-65. 2009
    ..Different strategies seem to have a greater impact on adenomas rather than on cancer detection rate. The study provides information when deciding screening protocols and to adapt them to local resources...
  49. ncbi Risk of endometrial cancer in breast cancer patients under long-term adjuvant treatment with tamoxifen
    S Cecchini
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 84:21-3. 1998
    ..Surveillance based on endometrial ultrasonography was poorly sensitive, but the favorable stage at diagnosis of screen-detected or interval endometrial cancers does not support a more aggressive screening approach...
  50. ncbi The role of fine needle aspiration cytology in the differential diagnosis of suspected breast cancer local recurrences
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 76:225-6. 1990
    ..96 and 0.97, respectively. The routine use of FNAC is recommended since it helps in the differential diagnosis of suspicious cases and may bypass surgical biopsy of positive cases not eligible for surgical treatment...
  51. pmc Chest X-ray survey in the follow-up of breast cancer patients
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Br J Cancer 60:102-3. 1989
    ..Periodic CXR survey looks a very questionable policy as it does not seem to have any favourable impact on prognosis. Its routine use in breast cancer patients should thus be carefully reconsidered...
  52. pmc Prediction of high-grade cervical intraepithelial neoplasia in cytologically normal women by human papillomavirus testing
    F Carozzi
    Cytology Unit, Centre for Cancer Study and Prevention CSPO, Firenze, Italy
    Br J Cancer 83:1462-7. 2000
    ..They also suggest that testing women negative for high-risk HPV at longer interval and strictly following-up women who are HPV positive could be an effective strategy for cervical cancer screening...
  53. ncbi Florence-Sydney Breast Biopsy Study: sensitivity of ultrasound-guided versus freehand fine needle biopsy of palpable breast cancer
    N Houssami
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Breast Cancer Res Treat 89:55-9. 2005
    ..It is unknown whether, for palpable cancers, ultrasound-guided FNAB is more accurate than freehand FNAB, and practice varies between physicians, services and countries...
  54. ncbi Colposcopy as a primary screening test for cervical cancer
    S Cecchini
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 83:810-3. 1997
    ..At least in those settings where access to cytopathology may be difficult, screening by colposcopy should be considered as a possible alternative...
  55. pmc Effect of rehydration on guaiac-based faecal occult blood testing in colorectal cancer screening
    G Castiglione
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Br J Cancer 67:1142-4. 1993
    ..We conclude that rehydrated HO should be introduced as the standard test for screening in order to increase sensitivity for colorectal cancer and adenomas...
  56. doi Early detection of second breast cancers improves prognosis in breast cancer survivors
    N Houssami
    Istituto per lo Studio e la Prevenzione Oncologica, Istituto scientifico della Regione Toscana, Florence, Italy
    Ann Oncol 20:1505-10. 2009
    ..We examined the prognostic effect of detection of ipsilateral breast relapse (IBR) or contralateral breast cancer (CBC) in the asymptomatic relative to symptomatic phase...
  57. ncbi Telethermography and breast cancer risk prediction
    S Ciatto
    , Firenze, Italy
    Tumori 75:110-2. 1989
    ..Thus thermography did not show any practical role as a breast cancer risk indicator. Possible biases affecting previous reports suggesting the use of thermography as a breast cancer risk indicator are discussed...
  58. ncbi Training in colposcopy: experience with a videocolposcopy test
    S Cecchini
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 83:650-2. 1997
    ..Tape-recorded videocolposcopy tests are a good, simple, practical and inexpensive method for interobserver quality control of colposcopic performance...
  59. ncbi Time trends of benign/malignant breast biopsy ratios a multicenter Italian study
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 82:325-8. 1996
    ..Acceptable (< 40 = 5, 40-49 = 1.5, 50-59 = 0.75, > 59 = 0.3) and desirable (2.5, 0.75, 0.35, 0.15) age specific reference standards for B/M are proposed...
  60. ncbi Evaluation of diagnostic accuracy of screening by fecal occult blood testing (FOBT). Comparison of FOB Gold and OC Sensor assays in a consecutive prospective screening series
    T Rubeca
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Int J Biol Markers 21:157-61. 2006
    ....
  61. ncbi Risk of infiltrating breast cancer subsequent to lobular carcinoma in situ. The Coordinating Center and Writing Committee of FONCAM (National Task Force for Breast Cancer)
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, , Italy
    Tumori 78:244-6. 1992
    ..The study confirms the higher risk of ipsilateral and contralateral cancer in LCIS patients and warns about the possible hazards of limited surgery in these cases...
  62. ncbi Comparing two modalities of management of women with cytologic evidence of squamous or glandular atypia: early repeat cytology or colposcopy
    S Cecchini
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 83:732-4. 1997
    ..The policy of repeat smear was more cost-effective than immediate colposcopy. According to such results, the protocol of the Florence screening program has been modified since October 1996...
  63. ncbi Measurement of the cost of screening for cervical cancer in the district of Florence, Italy
    M Zappa
    Centre for the Study and Prevention of Cancer (CSPO, Florence, Italy
    Tumori 84:631-5. 1998
    ..Different approaches and longer interval screening tests are discussed...
  64. ncbi Practice of opportunistic PSA screening in the Florence District
    M Zappa
    Descriptive and Epidemiological Unit, Center for Study and Prevention of Cancer CSPO, Via di San Salvi, 12, 50135, Florence, Italy
    Eur J Cancer Prev 12:201-4. 2003
    ..The aim of the present study was to evaluate the frequency of opportunistic screening by PSA in the District of Florence in the general population...
  65. ncbi Quality control of mammography screening in the Veneto Region. Evaluation of four programs at a local health unit level--analysis of the frequency and diagnostic pattern of interval cancers
    Marcello Vettorazzi
    Registro Tumori Veneto, Padova, Italy
    Tumori 92:1-5. 2006
    ..The aim of this study was to evaluate the sensitivity of the mammography screening program in four Local Health Units (ASL) and the possible causes of diagnostic error in cases further surfacing as interval cancers...
  66. ncbi Role of P16(INK4a) expression in identifying CIN2 or more severe lesions among HPV-positive patients referred for colposcopy after abnormal cytology
    Francesca Carozzi
    Center for the Study and Prevention of Cancer, Florence, Italy
    Cancer 108:119-23. 2006
    ....
  67. ncbi Analysis of morphologic patterns of fine-needle aspiration of the breast to reduce false-negative results in breast cytology
    Paolo Bulgaresi
    Laboratory Unit, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Cancer 105:152-7. 2005
    ..The main objective of the current study was to identify a morphologic pattern that may permit the reduction of false-negative findings while maintaining the specificity of FNAC...
  68. doi Breast screening with ultrasound in women with mammography-negative dense breasts: evidence on incremental cancer detection and false positives, and associated cost
    Vittorio Corsetti
    Ambulatori Oncologici Raphael, Cooperativa Sociale O N L U S, Calcinato BS, Italy
    Eur J Cancer 44:539-44. 2008
    ..We evaluated the contribution of ultrasound (US) in detecting breast cancer in women with dense breasts and negative mammograms...
  69. ncbi Quality assessment of the mammographic screening programme in the Azienda Sanitaria locale Provincia Milano 1 -- analysis of interval cancers and discussion of possible causes of diagnostic error
    Rossella Burani
    Azienda Sanitaria Locale Provincia Milano, Milan
    Radiol Med 109:260-7. 2005
    ..To evaluate the sensitivity of the mammographic screening programme and the causes of diagnostic fault in cases surfacing as interval cancers...
  70. ncbi Gastric cancer after positive screening faecal occult blood testing and negative assessment
    M Zappa
    Center for Study and Prevention of Cancer CSPO, Via di San Salvi, 12, 50135 Florence, Italy
    Dig Liver Dis 39:321-6. 2007
    ..Gastric cancer may be suspected with otherwise unexplained positive faecal occult blood testing...
  71. ncbi Interlaboratory reproducibility of atypical squamous cells of undetermined significance report: a national survey
    M Confortini
    Analytical and Biomolecular Cytology Unit, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Cytopathology 14:263-8. 2003
    ....
  72. pmc Lower protection of cytological screening for adenocarcinomas and shorter protection for younger women: the results of a case-control study in Florence
    M Zappa
    Clinical and Descriptive Epidemiological Unit, CSPO Centro per lo Studio e la Prevenzione Oncologica, Via di San Salvi 12, Florence 50135, Italy
    Br J Cancer 90:1784-6. 2004
    ..65 (95% confidence interval (CI) 0.26-1.64) and 0.15 (95% CI 0.07-0.31), for adenocarcinoma and squamous cancer, respectively. The duration of the protective effect was shorter in women below the age of 40 years than in older women...
  73. ncbi Performance of fine-needle aspiration cytology of the breast-multicenter study of 23,063 aspirates in ten Italian laboratories
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 81:13-7. 1995
    ..CONCLUSIONS: Although centers scored, on average, well within standards recommended by national authorities, this study suggests the opportunity of interlaboratory quality control to achieve more homogeneous criteria...
  74. ncbi Determinants of non-attendance to mammographic screening. Analysis of a population sample of the screening program in the District of Florence
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 78:22-5. 1992
    ..This might be regarded as unacceptable and however would involve high costs and a major organization effort...
  75. ncbi Cervical cancer screening in Tuscany: a survey of the actual state of cervical cancer prevention in the Local Sanitary Units of the Tuscan region
    S Cecchini
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italia
    Tumori 74:253-6. 1988
    ..The lack in the USL of epidemiologic competence and of cost/benefit considerations and the need for political decisions about cancer prevention programs are stressed...
  76. ncbi Mammography screening in elderly women: efficacy and cost-effectiveness
    Marco Zappa
    Descriptive and Epidemiological Unit, Center for Study and Prevention of Cancer CSPO, Scientific Institute of Tuscany Region, Via di San Salvi, 12, 50135, Florence, Italy
    Crit Rev Oncol Hematol 46:235-9. 2003
    ..Over the age of 74 years, encouraging individualized decisions may be more appropriate and may indicate further screening for those subjects for whom the potential benefit outweighs the potential negative effects...
  77. ncbi Full-field digital versus screen-film mammography: comparative accuracy in concurrent screening cohorts
    Marco Rosselli Del Turco
    Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Florence, Italy
    AJR Am J Roentgenol 189:860-6. 2007
    ..The purpose of this study was to compare the diagnostic accuracy of digital mammography with that of screen-film mammography in concurrent cohorts participating in the same population-based screening program...
  78. pmc Agreement between the AMPLICOR Human Papillomavirus Test and the Hybrid Capture 2 assay in detection of high-risk human papillomavirus and diagnosis of biopsy-confirmed high-grade cervical disease
    Francesca Carozzi
    Centro per lo Studio e la Prevenzione Oncologica, Unità Operativa Citologia Analitica e Molecolare, Via Cosimo il Vecchio 2, 50127 Firenze, Italy
    J Clin Microbiol 45:364-9. 2007
    ..7% of cases, while 21% of cases were negative. In conclusion, AMP provides a viable alternative to HC2, with good agreement for samples with high-grade cytology and similar sensitivity in detecting CIN2+ lesions...
  79. ncbi Conventional versus digital mammography in the analysis of screen-detected lesions with low positive predictive value
    Rita Bonardi
    Screening Unit, Centre for Study and Cancer Prevention CSPO, Florence, Italy
    Eur J Radiol 55:258-63. 2005
    ..To compare the performance of screen-film and digital mammography in the assessment of screen-detected breast lesions...
  80. ncbi A feasibility study of the use of the AutoPap screening system as a primary screening and location-guided rescreening device
    Massimo Confortini
    Cytology Unit, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Cancer 99:129-34. 2003
    ..Burlington, NC) is an automated device that was designed to screen conventionally prepared cervical smears and, more recently, thin-layer slide preparations. The system has been tested in large clinical trials...
  81. ncbi Increasing trends of cervical adenocarcinoma incidence in Central Italy despite Extensive Screening Programme, 1985-2000
    Carmen B Visioli
    Descriptive and Epidemiological Unit, Center for Study and Prevention of Cancer CSPO, Via di San Salvi, 12, 50135 Florence, Italy
    Cancer Detect Prev 28:461-4. 2004
    ..The burden of cervical cancers might increase in the future if no specific preventive strategies for adenocarcinoma are implemented...
  82. ncbi Triage with human papillomavirus testing of women with cytologic abnormalities prompting referral for colposcopy assessment
    Francesca Maria Carozzi
    Analytical and Biomolecular Cytology Unit, Centro per lo Studio e la Prevenzionc Oncologica, Florence, Italy
    Cancer 105:2-7. 2005
    ..The current study was conducted to evaluate the cost-effectiveness of triaging for colposcopy using human papillomavirus (HPV) testing...
  83. ncbi [Recommendations of a national Italian consensus conference on the opportunity of extending screening service by mammography to 40-49 and 70-74 years of age women]
    Vito Distante
    SOD Chirurgia generale II, AO universitaria, Careggi, Firenze
    Epidemiol Prev 31:15-22. 2007
    ....
  84. ncbi Large-scale randomized prostate cancer screening trials: program performances in the European Randomized Screening for Prostate Cancer trial and the Prostate, Lung, Colorectal and Ovary cancer trial
    Harry J de Koning
    Department of Public Health, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Int J Cancer 97:237-44. 2002
    ..The differences between countries seem to reflect both underlying prostate cancer incidence and screening policy. The trials have the power to show definitive results in 2005-2008...
  85. pmc Reliability of PSA testing remains unclear
    Stefano Ciatto
    BMJ 327:750. 2003
  86. ncbi Detection rates of high-grade prostate cancer during subsequent screening visits. Results of the European Randomized Screening Study for Prostate Cancer
    Theodorus H van der Kwast
    Department of Pathology and Urology, Erasmus Medical Center, Rotterdam, The Netherlands, and Centro per la Studio e la Prevenzione Oncologica, University of Florence, Italy
    Int J Cancer 118:2538-42. 2006
    ..e. 507/10,000 men). Variations in detection rates among screening centers related among others to biopsy compliance and age range...
  87. ncbi Positive predictive value of breast fine needle aspiration cytology (FNAC) in combination with clinical and imaging findings: a series of 2334 subjects with abnormal cytology
    P Bulgaresi
    Centro per lo Studio e la Prevenzione Oncologica CSPO, Tuscany Cancer Institute, Florence, Italy
    Breast Cancer Res Treat 97:319-21. 2006
    ....
  88. pmc Borderline breast core needle histology: predictive values for malignancy in lesions of uncertain malignant potential (B3)
    N Houssami
    Department of Diagnostic Imaging, Centro per lo Studio e la Prevenzione Oncologica, Viale A Volta 171, 50131 Florence, Italy
    Br J Cancer 96:1253-7. 2007
    ..Research is needed to improve differentiation between malignant and benign diseases in B3 lesions using diagnostic or predictive methods...
  89. pmc The detectability of breast cancer by screening mammography
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Br J Cancer 71:337-9. 1995
    ..As diagnostic assessment of minimal lesions is far from being 100% accurate, this policy would also considerably increase the frequency of unnecessary benign biopsies. All these negative effects might turn out to be unacceptable...
  90. ncbi Breast cancer diagnosis under the age of forty years
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italia
    Tumori 73:457-61. 1987
    ....
  91. doi Early detection of breast cancer: overview of the evidence on computer-aided detection in mammography screening
    N Houssami
    Screening and Test Evaluation Program, School of Public Health, University of Sydney, Sydney, NSW 2006, Australia
    J Med Imaging Radiat Oncol 53:171-6. 2009
    ..Refinement in CAD algorithms, in combination with increasing implementation of digital mammography, may improve the potential use of CAD in mammography reading, but will require prospective evaluation...
  92. ncbi Trends in the prevalence of cervical intraepithelial neoplasia grade 3 in the district of Florence, Italy
    S Cecchini
    Centro per lo Studio e la Prevenzione Oncologica (CSPO, Florence, Italy
    Tumori 81:330-3. 1995
    ..An increase in frequency of precancerous lesions for cervical cancer in more recent birth cohorts supports the need to keep screening coverage and efficiency as high as possible...
  93. ncbi Clinical impact (cost-effectiveness) of qualifying atypical squamous cells of undeterminate significance (ASCUS) in cases favoring a reactive or dysplastic process
    F M Carozzi
    Analytical and Biomolecular Cytology Unit, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Diagn Cytopathol 29:4-7. 2003
    ..The evidence that ASCUS detection option implies a higher detection rate of CIN2> and subsequently a lower cost per CIN2> detection must be considered with caution and deserves confirmation by other comparative studies...
  94. ncbi Hemoccult sensitivity estimate in a screening program for colorectal cancer in the Province of Florence
    G Castiglione
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 77:243-5. 1991
    ..Screening every year would achieve too limited an increase in sensitivity, compared to biennal screening, to be worth the difficulties of doubling organizational efforts and costs...
  95. ncbi [Assessment of diagnostic accuracy of mammography carried out for secondary prevention. Results of a test with a sample caseload conducted by 75 Italian radiologists]
    D Morrone
    Centro per lo Studio e la Prevenzione Oncologica, Azienda Ospedaliera Careggi, Firenze
    Radiol Med 101:44-7. 2001
    ..Seeding proficiency tests with cancers with minimal signs was of no benefit as far as evaluation is concerned...
  96. ncbi [Proficiency test in clinical mammography. Results of a consecutive series of 130 volunteer Italian radiologists]
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze
    Radiol Med 98:255-8. 1999
    ..We evaluated the results obtained by 130 Italian radiologists undergoing a proficiency test of clinical mammography...
  97. ncbi Screening history of incident cases of invasive carcinoma of the cervix. Florence district 1988-1989
    S Ciatto
    Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy
    Tumori 79:311-3. 1993
    ..Immediate evaluation of the screening history of incident cases of cervicocarcinoma should be mandatory in any screening program...
  98. doi Accuracy and surgical impact of magnetic resonance imaging in breast cancer staging: systematic review and meta-analysis in detection of multifocal and multicentric cancer
    Nehmat Houssami
    Screening and Test Evaluation Program, School of Public Health, University of Sydney, Sydney, Australia
    J Clin Oncol 26:3248-58. 2008
    ..Randomized trials are needed to determine the clinical value of detecting additional disease which changes surgical treatment in women with apparently localized breast cancer...
  99. doi Cost evaluation in a colorectal cancer screening programme by faecal occult blood test in the District of Florence
    Grazia Grazzini
    ISPO Cancer Prevention and Research Institute Florence, Istituto Tumori Toscano, Viale A Volta 171, 50131 Firenze, Italy
    J Med Screen 15:175-81. 2008
    ..To evaluate the direct costs of first and repeat colorectal cancer screening by immunochemical faecal occult blood testing (I-FOBT)...
  100. ncbi Negligible advantages and excess costs of routine addition of breast ultrasonography to mammography in dense breasts
    Beniamino Brancato
    Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
    Tumori 93:562-6. 2007
    ..To assess the role of breast ultrasonography as a complement to negative mammography in radiologically dense breasts...