Gian Franco Zannoni

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. ncbi request reprint Mutational status of KRAS, NRAS, and BRAF in primary clear cell ovarian carcinoma
    Gian Franco Zannoni
    Department of Pathology, Catholic University of the Sacred Heart, Largo A Gemelli, 8, Rome, Italy
    Virchows Arch 465:193-8. 2014
  2. ncbi request reprint Secondary malignancies of the uterine cervix: a potential diagnostic pitfall
    Gian Franco Zannoni
    Department of Pathology, Catholic University of the Sacred Heart, Rome, Italy
    Virchows Arch 463:23-9. 2013
  3. doi request reprint Clinicopathologic and immunohistochemical features of ovarian clear cell carcinomas in comparison with type I and type II tumors
    Gian Franco Zannoni
    Departments of Pathology, Catholic University of the Sacred Heart, Rome, Italy
    Int J Gynecol Pathol 31:507-16. 2012
  4. doi request reprint Colonic carcinoma metastatic to the endometrium: the importance of clinical history in averting misdiagnosis as a primary endometrial carcinoma
    Gian Franco Zannoni
    Department of Pathology, Policlinico A Gemelli, Catholic University, Largo A Gemelli 8, 00168 Rome, Italy
    Int J Surg Pathol 19:787-90. 2011
  5. pmc CD133 antigen expression in ovarian cancer
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Department of Oncology, Catholic University, Campobasso, Italy
    BMC Cancer 9:221. 2009
  6. doi request reprint Morphological effects of radiochemotherapy on cervical carcinoma: a morphological study of 50 cases of hysterectomy specimens after neoadjuvant treatment
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University, Rome, Italy
    Int J Gynecol Pathol 27:274-81. 2008
  7. doi request reprint Morphology and immunophenotyping of a monolateral ovotestis in a 46,XderY/45,X mosaic individual with ambiguous genitalia
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine A Gemelli, Catholic University of the Sacred Heart, Rome, Italy
    Int J Gynecol Pathol 29:33-8. 2010
  8. ncbi request reprint Ovarian endomyometrioma with atypias: description of a case
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University, Rome, Italy
    Fertil Steril 88:1438.e15-7. 2007
  9. ncbi request reprint Ovarian serous carcinoma presenting with mediastinal lymphadenopathy 20 months before the intraabdominal mass: role of immunohistochemistry
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University, 00168 Rome, Italy
    Gynecol Oncol 104:497-500. 2007
  10. ncbi request reprint Oligodendroglioma arising within a mature cystic ovarian teratoma: case report and review of the literature
    Gian Franco Zannoni
    Division of Anatomic Pathology and Histology, Catholic University of the Sacred Heart, Agostino Gemelli Faculty of Medicine, Largo Francesco Vito 1, 00168 Rome, Italy
    Acta Obstet Gynecol Scand 81:896-7. 2002

Collaborators

Detail Information

Publications60

  1. ncbi request reprint Mutational status of KRAS, NRAS, and BRAF in primary clear cell ovarian carcinoma
    Gian Franco Zannoni
    Department of Pathology, Catholic University of the Sacred Heart, Largo A Gemelli, 8, Rome, Italy
    Virchows Arch 465:193-8. 2014
    ..These OCCC were unilateral FIGO stage IA lesions in two cases associated with foci of endometriosis. We conclude that in 14 % of OCCCs, a KRAS mutation occurs in codon 2 exon 2. NRAS and BRAF mutations were not found. ..
  2. ncbi request reprint Secondary malignancies of the uterine cervix: a potential diagnostic pitfall
    Gian Franco Zannoni
    Department of Pathology, Catholic University of the Sacred Heart, Rome, Italy
    Virchows Arch 463:23-9. 2013
    ..Histopathology, as well as immunohistochemical features and close collaboration between clinicians and pathologists, is essential to arrive at a correct final diagnosis...
  3. doi request reprint Clinicopathologic and immunohistochemical features of ovarian clear cell carcinomas in comparison with type I and type II tumors
    Gian Franco Zannoni
    Departments of Pathology, Catholic University of the Sacred Heart, Rome, Italy
    Int J Gynecol Pathol 31:507-16. 2012
    ..In conclusion, our study provides insights into clear cell carcinoma that could help in explaining its unique prognostic features, and, eventually, in orienting toward new therapeutic options...
  4. doi request reprint Colonic carcinoma metastatic to the endometrium: the importance of clinical history in averting misdiagnosis as a primary endometrial carcinoma
    Gian Franco Zannoni
    Department of Pathology, Policlinico A Gemelli, Catholic University, Largo A Gemelli 8, 00168 Rome, Italy
    Int J Surg Pathol 19:787-90. 2011
    ..In these cases clinical history is crucial and an immunohistochemical panel made up of CK7, CK20, CDX2, p53, vimentin, ER, and PR is useful for the correct diagnosis...
  5. pmc CD133 antigen expression in ovarian cancer
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Department of Oncology, Catholic University, Campobasso, Italy
    BMC Cancer 9:221. 2009
    ..The aim of the study was to investigate the clinical role of the immunohistochemically assessed expression of CD133 in a large single Institution series of ovarian cancer patients...
  6. doi request reprint Morphological effects of radiochemotherapy on cervical carcinoma: a morphological study of 50 cases of hysterectomy specimens after neoadjuvant treatment
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University, Rome, Italy
    Int J Gynecol Pathol 27:274-81. 2008
    ..In most cases, morphological criteria are sufficient to make a diagnosis, but sometimes, the use of immunohistochemistry (keratins and CD68) is a mandatory method to reveal the nature of the lesion...
  7. doi request reprint Morphology and immunophenotyping of a monolateral ovotestis in a 46,XderY/45,X mosaic individual with ambiguous genitalia
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine A Gemelli, Catholic University of the Sacred Heart, Rome, Italy
    Int J Gynecol Pathol 29:33-8. 2010
    ..The presence of placental-like alkaline phosphatase-stained gonocytes indicates a high risk of malignant transformation, and justifies the surgical removal of the dysgenetic gonad. Fertility is unlikely...
  8. ncbi request reprint Ovarian endomyometrioma with atypias: description of a case
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University, Rome, Italy
    Fertil Steril 88:1438.e15-7. 2007
    ..To report on a patient with endomyometrioma with atypias and to review the literature...
  9. ncbi request reprint Ovarian serous carcinoma presenting with mediastinal lymphadenopathy 20 months before the intraabdominal mass: role of immunohistochemistry
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University, 00168 Rome, Italy
    Gynecol Oncol 104:497-500. 2007
    ..Metastatic involvement of the mediastinal lymph nodes is an extremely uncommon finding in epithelial ovarian cancers...
  10. ncbi request reprint Oligodendroglioma arising within a mature cystic ovarian teratoma: case report and review of the literature
    Gian Franco Zannoni
    Division of Anatomic Pathology and Histology, Catholic University of the Sacred Heart, Agostino Gemelli Faculty of Medicine, Largo Francesco Vito 1, 00168 Rome, Italy
    Acta Obstet Gynecol Scand 81:896-7. 2002
  11. doi request reprint Does high-grade endometrioid carcinoma (grade 3 FIGO) belong to type I or type II endometrial cancer? A clinical-pathological and immunohistochemical study
    Gian Franco Zannoni
    Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University of the Sacred Heart, Largo F Vito 1, 00168, Rome, Italy
    Virchows Arch 457:27-34. 2010
    ..Further research is needed to clarify the clinical value of this observation...
  12. ncbi request reprint Estradiol and phytoestrogens differently influence the rodent postmenopausal mammary gland
    Daniela Gallo
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Menopause 13:72-9. 2006
    ..Additionally, mammary receptor regulation was extensively evaluated by immunohistochemical analysis, and tissue proliferative activity analyzed by cell nuclear proliferating antigen expression (Ki67)...
  13. pmc Clinical performance of human papillomavirus E6 and E7 mRNA testing for high-grade lesions of the cervix
    Paola Cattani
    Institute of Microbiology, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, Rome 00168, Italy
    J Clin Microbiol 47:3895-901. 2009
    ..3% and 49.0%, respectively). These findings suggest that mRNA assays could be more powerful than DNA testing for predicting the risk of progression and offer a strong potential as a tool for triage and patient follow-up...
  14. ncbi request reprint Prognostic role of the ratio between cyclooxygenase-2 in tumor and stroma compartments in cervical cancer
    Gabriella Ferrandina
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Clin Cancer Res 10:3117-23. 2004
    ..The aim of this study was to analyze the clinical role of cyclooxygenase (COX)-2 in a large series of 175 cervical cancer patients...
  15. doi request reprint Class III β-tubulin and the cytoskeletal gateway for drug resistance in ovarian cancer
    Marta De Donato
    Laboratory of Antineoplastic Pharmacology, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    J Cell Physiol 227:1034-41. 2012
    ....
  16. ncbi request reprint Prognostic role of metastasis tumor antigen 1 in patients with ovarian cancer: a clinical study
    Maria Grazia Prisco
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Largo A Gemelli, 8 00168, Rome, Italy
    Hum Pathol 43:282-8. 2012
    ..These findings indicate that metastasis tumor antigen 1 overexpression can be used as a predictor of clinical outcome in patients with ovarian cancer and therefore may represent a new prognostic marker...
  17. ncbi request reprint Antiproliferative and antiangiogenic effects of the benzophenanthridine alkaloid sanguinarine in melanoma
    Ilaria De Stefano
    Laboratory of Antineoplastic Pharmacology, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Largo A Gemelli 8, 00168 Rome, Italy
    Biochem Pharmacol 78:1374-81. 2009
    ..Sanguinarine also showed a striking antiangiogenic activity in mice. Data from the present study support the concept that sanguinarine can be effective in melanoma skin cancer...
  18. ncbi request reprint Sox9 and Hif-2α regulate TUBB3 gene expression and affect ovarian cancer aggressiveness
    Giuseppina Raspaglio
    Translational Research Centre in Gynecological Cancer, Department of Gynecology, Catholic University of the Sacred Heart, Rome, Italy Electronic address
    Gene 542:173-81. 2014
    ..Patients displaying no expression for the three genes had the best outcome. A poor prognosis significant in multivariate analysis was visible in patients featuring high expression of βIII-tubulin and nuclear Sox9...
  19. ncbi request reprint Expression of cyclooxygenase-2 (COX-2), receptors for estrogen (ER), and progesterone (PR), p53, ki67, and neu protein in endometrial cancer
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Catholic University of Rome, Catholic University of the Sacred Heart, Largo F Vito 1, 00168 Rome, Italy
    Gynecol Oncol 98:383-9. 2005
    ..The simultaneous assessment of p53 protein, ki67, and neu protein has been carried out...
  20. ncbi request reprint Expression of cyclooxygenase-2 (COX-2) in non-neoplastic and neoplastic vulvar epithelial lesions
    Gabriella Ferrandina
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Gynecol Oncol 92:537-44. 2004
    ..We investigated by immunohistochemistry the expression of COX-2 in normal vulvar tissue, non-neoplastic vulvar epithelial lesions, vulvar intraepithelial neoplasia (VIN) and invasive vulvar cancer (IVC)...
  21. ncbi request reprint Cytoplasmic expression of estrogen receptor beta (ERβ) predicts poor clinical outcome in advanced serous ovarian cancer
    Ilaria De Stefano
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Gynecol Oncol 122:573-9. 2011
    ..The study also included 12 macroscopically and histopathologically normal ovaries...
  22. doi request reprint BRAF (V600E) mutation analysis on liquid-based cytology-processed aspiration biopsies predicts bilaterality and lymph node involvement in papillary thyroid microcarcinoma
    Esther Diana Rossi
    Division of Anatomic Pathology and Histology, Agostino Gemelli School of Medicine, Catholic University of Sacred Heart, Rome, Italy
    Cancer Cytopathol 121:291-7. 2013
    ....
  23. doi request reprint Effects of epidermal growth factor receptor blockade on ependymoma stem cells in vitro and in orthotopic mouse models
    Tiziana Servidei
    Department of Pediatric Oncology, Catholic University, Rome, Italy
    Int J Cancer 131:E791-803. 2012
    ..The experimental models we developed can be used to further investigate the activity of EGFR inhibitors or other antineoplastic agents in this tumor...
  24. doi request reprint HuR regulates beta-tubulin isotype expression in ovarian cancer
    Giuseppina Raspaglio
    Laboratory of Antineoplastic Pharmacology, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Cancer Res 70:5891-900. 2010
    ..Finally, the clinical value of this finding was assessed in a clinical cohort of 46 ovarian cancer patients in whom it was found that HuR cytoplasmic staining was associated with high levels of TUBB3 and poor survival...
  25. ncbi request reprint Expression of class III beta tubulin in cervical cancer patients administered preoperative radiochemotherapy: correlation with response to treatment and clinical outcome
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Catholic University, Rome, Italy
    Gynecol Oncol 104:326-30. 2007
    ....
  26. doi request reprint The expression ratios of estrogen receptor α (ERα) to estrogen receptor β1 (ERβ1) and ERα to ERβ2 identify poor clinical outcome in endometrioid endometrial cancer
    Gian Franco Zannoni
    Department of Histopathology, Catholic University of the Sacred Heart, Largo A Gemelli, 8 00168, Rome, Italy
    Hum Pathol 44:1047-54. 2013
    ....
  27. ncbi request reprint Soy phytochemicals decrease nonsmall cell lung cancer growth in female athymic mice
    Daniela Gallo
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, 00168 Rome, Italy
    J Nutr 138:1360-4. 2008
    ..Our research provides further support for the concept that consumption of phytoestrogens may be effective in delaying lung cancer progression...
  28. ncbi request reprint Prognostic significance of the estrogen receptor beta (ERβ) isoforms ERβ1, ERβ2, and ERβ5 in advanced serous ovarian cancer
    Alessandra Ciucci
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Gynecol Oncol 132:351-9. 2014
    ..In the present study we have examined the pattern of expression of the full length estrogen receptor β (ERβ1) and two ERβ splice variant isoforms (ERβ2, ERβ5) in well-characterized advanced serous ovarian cancers...
  29. pmc Cyclo-oxygenase-2 (Cox-2) expression and resistance to platinum versus platinum/paclitaxel containing chemotherapy in advanced ovarian cancer
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Catholic University, L, go Gemelli 8, 00168, Rome, Italy
    BMC Cancer 6:182. 2006
    ..To our knowledge, no data has been reported until now about the association between COX-2 status and response to different chemotherapy regimens...
  30. doi request reprint Hyaluronic acid-paclitaxel: effects of intraperitoneal administration against CD44(+) human ovarian cancer xenografts
    Ilaria De Stefano
    Department of Obstetrics and Gynaecology, Catholic University of the Sacred Heart, Largo A Gemelli, 8, 00168 Rome, Italy
    Cancer Chemother Pharmacol 68:107-16. 2011
    ..Here, we evaluated the potential application of a new HA-paclitaxel bioconjugate, ONCOFID-P, for intraperitoneal (IP) treatment of ovarian cancer...
  31. ncbi request reprint Class III beta-tubulin overexpression is a marker of poor clinical outcome in advanced ovarian cancer patients
    Gabriella Ferrandina
    Department of Oncology, Catholic University, Campobasso, Italy
    Clin Cancer Res 12:2774-9. 2006
    ..We also investigated whether beta III tubulin expression could be modified after the selective pressure represented by chemotherapy in vivo...
  32. pmc Gender Effect in Experimental Models of Human Medulloblastoma: Does the Estrogen Receptor β Signaling Play a Role?
    Alessandra Ciucci
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    PLoS ONE 9:e101623. 2014
    ..The male-to-female sex ratio for medulloblastoma (MB) is approximately 1.5∶1, female gender being also a favorable prognostic factor. This study aimed at evaluating the impact of gender on MB tumorigenesis...
  33. pmc Recurrence in skeletal muscle from squamous cell carcinoma of the uterine cervix: a case report and review of the literature
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Catholic University, L go Gemelli 8, 00168, Rome, Italy
    BMC Cancer 6:169. 2006
    ..The occurrence of skeletal muscle metastases is a very rare event. Only two cases of late skeletal muscle recurrence from cervical cancer have been documented until now...
  34. ncbi request reprint A case of isolated ovarian recurrence from vulvar carcinoma
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Department of Oncology, Catholic University of the Sacred Heart, Largo A Gemelli, 1, 86100 Campobasso, Italy
    Arch Gynecol Obstet 278:393-6. 2008
    ..This observation expands the range of unusual clinical presentations of recurrence sites from vulvar carcinoma, and emphasizes the need not to underestimate the role of long complete follow-up program in vulvar cancer patients...
  35. ncbi request reprint Aberrant expression of alpha-dystroglycan in cervical and vulvar cancer
    Alessandro Sgambato
    Centro di Ricerche Oncologiche Giovanni XXIII Istituto di Patologia Generale, Universita Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy
    Gynecol Oncol 103:397-404. 2006
    ..In this study, expression of dystroglycan was evaluated in the multistep cervical and vulvar tumorigenesis...
  36. ncbi request reprint Diagnostic efficacy of conventional as compared to liquid-based cytology in thyroid lesions: evaluation of 10,360 fine needle aspiration cytology cases
    Esther Diana Rossi
    Division of Anatomic Pathology, Catholic University of Sacred Heart, Rome, Italy
    Acta Cytol 53:659-66. 2009
    ..To evaluate the efficacy of thyroid fine needle aspiration cytology (FNAC) processed by liquid-based cytology (LBC) as compared to conventional smears (CS) in 10,360 consecutive cases in 3 reference periods...
  37. pmc Expression of the glioma-associated oncogene homolog 1 (gli1) in advanced serous ovarian cancer is associated with unfavorable overall survival
    Alessandra Ciucci
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    PLoS ONE 8:e60145. 2013
    ..However, our in vitro findings draw attention to the need for selection of appropriate experimental models that accurately represent human tumor for testing future therapies involving Hh pathway inhibitors...
  38. pmc Increased expression of CD133 and reduced dystroglycan expression are strong predictors of poor outcome in colon cancer patients
    Claudio Coco
    Dipartimento di Scienze Chirurgiche, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Exp Clin Cancer Res 31:71. 2012
    ..Expression levels of CD133, a cancer stem cell marker, and of the α-subunit of the dystroglycan (α-DG) complex, have been previously reported to be altered in colorectal cancers...
  39. pmc Application of liquid-based cytology to fine-needle aspiration biopsies of the thyroid gland
    Esther Diana Rossi
    Division of Anatomic Pathology and Histology, Agostino Gemelli School of Medicine and Hospital, Università Cattolica del Sacro Cuore Rome, Italy
    Front Endocrinol (Lausanne) 3:57. 2012
    ..The LBC-processed biopsies represent a valid alternative to conventional cytology. The possibility of applying special techniques enhance the efficacy of the cytological diagnosis of thyroid lesions...
  40. doi request reprint Gender influences the class III and V β-tubulin ability to predict poor outcome in colorectal cancer
    Marisa Mariani
    Danbury Hospital Research Institute, Danbury, Connecticut 00168, USA
    Clin Cancer Res 18:2964-75. 2012
    ..Colorectal cancer is one of the deadliest diseases in Western countries. To predict the outcome of therapy, we assessed the role of class III (TUBB3) and class V β-tubulin (TUBB6) as predictive biomarkers...
  41. ncbi request reprint Glassy cell carcinoma of the endometrium: a case report and review of the literature
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Catholic University, L go A Gemelli 8, 00168 Rome, Italy
    Pathol Res Pract 203:217-20. 2007
    ....
  42. doi request reprint Relevance of immunocytochemistry on thin-layer cytology in thyroid lesions suspicious for medullary carcinoma: a case-control study
    Esther Diana Rossi
    Endocrinology, Catholic University of Sacred Heart, Largo Francesco Vito, Rome, Italy
    Appl Immunohistochem Mol Morphol 16:548-53. 2008
    ..This diagnosis may be supported by immunocytochemistry (ICC), which may be difficult to carry out on the conventional smears...
  43. doi request reprint Can radicality of surgery be safely modulated on the basis of MRI and PET/CT imaging in locally advanced cervical cancer patients administered preoperative treatment?
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Department of Oncology, Catholic University, Campobasso, Italy
    Cancer 118:392-403. 2012
    ....
  44. pmc Antitumor effect in medulloblastoma cells by gefitinib: Ectopic HER2 overexpression enhances gefitinib effects in vivo
    Daniela Meco
    Department of Pediatric Oncology, Catholic University, Largo A Gemelli, 8, 00168 Rome, Italy
    Neuro Oncol 11:250-9. 2009
    ..Our data indicate that gefitinib might be a molecularly targeted agent for the treatment of MB...
  45. ncbi request reprint Frozen section examination of pelvic lymph nodes in endometrial and cervical cancer: accuracy in patients submitted to neoadjuvant treatments
    Francesco Fanfani
    Department of Oncology, Catholic University of the Sacred Heart, Campobasso, Italy
    Gynecol Oncol 94:779-84. 2004
    ....
  46. ncbi request reprint Characterization of the pharmacologic profile of a standardized soy extract in the ovariectomized rat model of menopause: effects on bone, uterus, and lipid profile
    Daniela Gallo
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Menopause 12:589-600. 2005
    ..This study was aimed to assess the effect of a standardized soy extract (SSE, Soyselect) in the ovariectomized rat model of menopause...
  47. ncbi request reprint Serous ovarian carcinoma recurring as a heterologous carcinosarcoma
    Gabriella Ferrandina
    Gynecologic Oncology Unit, Catholic University of Rome, Rome, Italy
    J Obstet Gynaecol Res 33:95-9. 2007
    ..The immunohistochemical analysis of several biological parameters in primary ovarian adenocarcinoma and recurrent carcinosarcoma has been also performed...
  48. ncbi request reprint Histopathological classification of esophageal carcinomas
    Valerio Gaetano Vellone
    Istituto di Anatomia Patologica, Universita Cattolica del S Cuore, Policlinico A Gemelli, Roma, Italy
    Rays 31:57-61. 2006
    ..All these data are crucial not only for prognosis but also for therapy planning...
  49. ncbi request reprint Morphological and immunocytochemical diagnosis of thyroiditis: Comparison between conventional and liquid-based cytology
    Esther Diana Rossi
    Division of Anatomic Pathology and Histology, Universita Cattolica del Sacro Cuore, Agostino Gemelli School of Medicine, Rome, Italy
    Diagn Cytopathol 40:404-9. 2012
    ..5%. Among these cases, 10 had a benign histology and a concordant negative ICC. LBC can be used as a valid method for HT, especially for the possible application of ICC to HN, and it allows a correct preoperative selection of lesions..
  50. doi request reprint Accuracy of Papanicolaou smears in cervical cancer patients treated with radiochemotherapy followed by radical surgery
    Gian Franco Zannoni
    Department of Pathology, Policlinico Gemelli, Catholic University, Rome, Italy
    Am J Clin Pathol 130:787-94. 2008
    ..Comparison of these results showed that the Pap test had a sensitivity of 0.16, a specificity of 0.96, a negative predictive value of 0.83, a positive predictive value of 0.42, and an accuracy of 0.46...
  51. ncbi request reprint Pseudo-Meigs' syndrome associated with malignant struma ovarii: a case report
    Gian Franco Zannoni
    Institute of Pathology, Catholic University, 00168, Rome, Italy
    Gynecol Oncol 94:226-8. 2004
    ..Malignant struma ovarii is a rare tumor, consisting of a struma ovarii with malignant transformation. The association of a malignant struma ovarii with pseudo-Meigs' syndrome and elevated Ca-125 levels has been never reported...
  52. pmc Dual Inhibitor AEE788 Reduces Tumor Growth in Preclinical Models of Medulloblastoma
    Daniela Meco
    Department of Pediatric Oncology, Catholic University, Rome, Italy
    Transl Oncol 3:326-35. 2010
    ....
  53. ncbi request reprint p16 ink4a and HPV L1 immunohistochemistry is helpful for estimating the behavior of low-grade dysplastic lesions of the cervix uteri
    Giovanni Negri
    Department of Pathology, Central Hospital Bolzano, Bolzano, Italy
    Am J Surg Pathol 32:1715-20. 2008
    ..Particularly in cases in which the grade of the lesion is morphologically difficult to assess, the p16/L1 expression pattern could be useful for planning the clinical management of these women...
  54. ncbi request reprint Asymptomatic intrathyroidal parathyroid adenoma. Report of a case with a cytologic differential diagnosis including thyroid neoplasms
    Esther Diana Rossi
    Division of Anatomic Pathology and Histology, Catholic University of the Sacred Heart, Largo Francesco Vito, 1, 00168 Rome, Italy
    Acta Cytol 48:437-40. 2004
    ..When asymptomatic, they can be incorrectly diagnosed as thyroid neoplasms on fine needle aspiration biopsy (FNAB), leading to inappropriate surgical treatment...
  55. pmc RNA (E6 and E7) assays versus DNA (E6 and E7) assays for risk evaluation for women infected with human papillomavirus
    Paola Cattani
    Institute of Microbiology, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Clin Microbiol 47:2136-41. 2009
    ..These results suggest that testing for HPV E6 and E7 transcripts could be a useful tool for screening and patient management, providing more accurate predictions of risk than those obtained by DNA testing...
  56. ncbi request reprint Chromosome 9p deletion syndrome and sex reversal: novel findings and redefinition of the critically deleted regions
    Roberta Onesimo
    Department of Pediatrics, Catholic University School of Medicine, and Department Pediatric Surgery, San Camillo de Lellis Hospital, Rome, Italy
    Am J Med Genet A 158:2266-71. 2012
    ..Our observations expand the 9p deletion clinical spectrum, and add significantly to the definition of a 9p-syndrome critical region...
  57. ncbi request reprint Simultaneous ovarian and endometrial osseous metaplasia: a case report
    Sebastiano Campo
    Department of Obstetrics and Gynecology, Division of Anatomic Pathology and Histology, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Reprod Med 52:241-2. 2007
    ..Endometrial ossification is a rare disease. More than 80% of cases occur after pregnancy, but it has been observed in patients with a history of endometritis, dilation and curettage, and metabolic disorders...
  58. ncbi request reprint Decreased expression of the CDK inhibitor p27Kip1 and increased oxidative DNA damage in the multistep process of cervical carcinogenesis
    Alessandro Sgambato
    Centro di Ricerche Oncologiche Giovanni XXIII, Istituto di Anatomia Patologica, Universita Cattolica del Sacro Cuore, Rome, Italy
    Gynecol Oncol 92:776-83. 2004
    ..The expression of the CDK inhibitor p27Kip1 and the extent of endogenous oxidative DNA damage were evaluated in the multistep cervical carcinogenesis...
  59. ncbi request reprint Cyclooxygenase-2 expression in lymph node metastasis of cervical and vulvar cancer
    Gabriella Ferrandina
    Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
    Oncol Rep 10:1799-804. 2003
    ....
  60. ncbi request reprint Frequent loss of pRb2/p130 in human ovarian carcinoma
    Giuseppina D'Andrilli
    Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA
    Clin Cancer Res 10:3098-103. 2004
    ..2, a region in which deletions have been found in several human neoplasms including breast, prostatic, and ovarian carcinoma. We sought to evaluate pRb2/p130 protein expression and function in ovarian carcinoma...