Evelina Tacconelli

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. ncbi request reprint New strategies to identify patients harbouring antibiotic-resistant bacteria at hospital admission
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    Clin Microbiol Infect 12:102-9. 2006
  2. doi request reprint Identifying risk factors for infections: the role of meta-analyses
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, Roma, Italy
    Infect Dis Clin North Am 23:211-24. 2009
  3. pmc Nosocomial acquisition of methicillin-resistant Staphyloccocus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) Enterobacteriaceae in hospitalised patients: a prospective multicenter study
    Giulia De Angelis
    Department of Infectious Diseases, Universita Cattolica del Sacro Cuore, Largo F, VITO, 1 00168 Rome, Italy
    BMC Infect Dis 12:74. 2012
  4. pmc Antibiotic usage and risk of colonization and infection with antibiotic-resistant bacteria: a hospital population-based study
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica del Sacro Cuore, Rome, Italy
    Antimicrob Agents Chemother 53:4264-9. 2009
  5. doi request reprint Antimicrobial use: risk driver of multidrug resistant microorganisms in healthcare settings
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, Rome, Italy
    Curr Opin Infect Dis 22:352-8. 2009
  6. doi request reprint Pneumonia due to methicillin-resistant Staphylococcus aureus: clinical features, diagnosis and management
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, Rome, Italy
    Curr Opin Pulm Med 15:218-22. 2009
  7. doi request reprint Vancomycin-resistant enterococci (VRE): transmission and control
    Evelina Tacconelli
    Division Infectious Diseases, Catholic University, Largo F Vito, 100168, Rome, Italy
    Int J Antimicrob Agents 31:99-106. 2008
  8. doi request reprint Prediction models to identify hospitalized patients at risk of being colonized or infected with multidrug-resistant Acinetobacter baumannii calcoaceticus complex
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, 00168 Rome, Italy
    J Antimicrob Chemother 62:1130-7. 2008
  9. doi request reprint Vancomycin versus cefazolin prophylaxis for cerebrospinal shunt placement in a hospital with a high prevalence of meticillin-resistant Staphylococcus aureus
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    J Hosp Infect 69:337-44. 2008
  10. ncbi request reprint Does antibiotic exposure increase the risk of methicillin-resistant Staphylococcus aureus (MRSA) isolation? A systematic review and meta-analysis
    Evelina Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    J Antimicrob Chemother 61:26-38. 2008

Detail Information

Publications48

  1. ncbi request reprint New strategies to identify patients harbouring antibiotic-resistant bacteria at hospital admission
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    Clin Microbiol Infect 12:102-9. 2006
    ..Current studies are analysing risk-factors for harbouring multiresistant Gram-negative bacteria at hospital admission...
  2. doi request reprint Identifying risk factors for infections: the role of meta-analyses
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, Roma, Italy
    Infect Dis Clin North Am 23:211-24. 2009
    ....
  3. pmc Nosocomial acquisition of methicillin-resistant Staphyloccocus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) Enterobacteriaceae in hospitalised patients: a prospective multicenter study
    Giulia De Angelis
    Department of Infectious Diseases, Universita Cattolica del Sacro Cuore, Largo F, VITO, 1 00168 Rome, Italy
    BMC Infect Dis 12:74. 2012
    ....
  4. pmc Antibiotic usage and risk of colonization and infection with antibiotic-resistant bacteria: a hospital population-based study
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica del Sacro Cuore, Rome, Italy
    Antimicrob Agents Chemother 53:4264-9. 2009
    ..Identifying ARB colonization early during antibiotic therapy could target a high-risk hospitalized population that may benefit from intervention to decrease the risk of subsequent nosocomial infections...
  5. doi request reprint Antimicrobial use: risk driver of multidrug resistant microorganisms in healthcare settings
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, Rome, Italy
    Curr Opin Infect Dis 22:352-8. 2009
    ..This review explores recent evidence on the association between antibiotics usage and resistance...
  6. doi request reprint Pneumonia due to methicillin-resistant Staphylococcus aureus: clinical features, diagnosis and management
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, Rome, Italy
    Curr Opin Pulm Med 15:218-22. 2009
    ..The review highlights the clinical findings and the management of community-acquired, health-care associated and nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA)...
  7. doi request reprint Vancomycin-resistant enterococci (VRE): transmission and control
    Evelina Tacconelli
    Division Infectious Diseases, Catholic University, Largo F Vito, 100168, Rome, Italy
    Int J Antimicrob Agents 31:99-106. 2008
    ..Future prospective comparative studies of infection control approaches in different epidemiological situations might be useful...
  8. doi request reprint Prediction models to identify hospitalized patients at risk of being colonized or infected with multidrug-resistant Acinetobacter baumannii calcoaceticus complex
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, 00168 Rome, Italy
    J Antimicrob Chemother 62:1130-7. 2008
    ....
  9. doi request reprint Vancomycin versus cefazolin prophylaxis for cerebrospinal shunt placement in a hospital with a high prevalence of meticillin-resistant Staphylococcus aureus
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    J Hosp Infect 69:337-44. 2008
    ..02). Our data suggest that use of vancomycin as prophylactic agent for cerebrospinal shunt placement reduces the rate of shunt infections in the context of high prevalence of MRSA...
  10. ncbi request reprint Does antibiotic exposure increase the risk of methicillin-resistant Staphylococcus aureus (MRSA) isolation? A systematic review and meta-analysis
    Evelina Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    J Antimicrob Chemother 61:26-38. 2008
    ..A systematic review was performed to determine whether antibiotic exposure is a risk factor for the isolation of MRSA...
  11. ncbi request reprint Antimicrobial therapy of Staphylococcus aureus bloodstream infection
    Evelina Tacconelli
    Universita Cattolica S Cuore, Istituto Malattie Infettive, Largo F Vito 8, 00168 Roma, Italy
    Expert Opin Pharmacother 8:2505-18. 2007
    ..The review summarises evidence on present therapeutic options for the treatment of S. aureus BSI...
  12. doi request reprint Rapid screening tests for meticillin-resistant Staphylococcus aureus at hospital admission: systematic review and meta-analysis
    Evelina Tacconelli
    Department of Infectious Diseases, Catholic University of the Sacred Heart, Rome, Italy
    Lancet Infect Dis 9:546-54. 2009
    ....
  13. doi request reprint Screening and isolation for infection control
    E Tacconelli
    Department of Infectious Diseases, Universita Cattolica Sacro Cuore, Rome, Italy
    J Hosp Infect 73:371-7. 2009
    ..Based on these studies, definitive recommendations cannot be made...
  14. doi request reprint National guidelines for decolonization of methicillin-resistant Staphylococcus aureus carriers: the implications of recent experience in the Netherlands
    Evelina Tacconelli
    Department of Infectious Disease, Universita Cattolica, Largo F Vito 1, 00168, Rome, Italy
    J Antimicrob Chemother 66:2195-8. 2011
    ....
  15. ncbi request reprint Glycopeptide resistance among coagulase-negative staphylococci that cause bacteremia: epidemiological and clinical findings from a case-control study
    E Tacconelli
    Department of Infectious, Catholic University, Rome, Italy
    Clin Infect Dis 33:1628-35. 2001
    ..Mortality rates were 25% among case patients and 18% among control patients, and they were significantly higher among patients who presented with concomitant pneumonia and a high Acute Physiology and Chronic Health Evaluation III score...
  16. doi request reprint Methicillin-resistant Staphylococcus aureus: source control and surveillance organization
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    Clin Microbiol Infect 15:31-8. 2009
    ..The existing evidence does not support the wide application of rapid molecular screening for MRSA...
  17. doi request reprint Fighting antibiotic resistance all over Europe
    Evelina Tacconelli
    Department of Infectious Diseases, Universita Cattolica del Sacro Cuore, Largo F Vito, 1 00168 Rome, Italy
    Expert Rev Anti Infect Ther 8:761-3. 2010
    ..The participation of a such significant number of scientists presented a unique opportunity for discussion on several clinical and research topics...
  18. pmc Older age does not influence CD4 cell recovery in HIV-1 infected patients receiving highly active antiretroviral therapy
    Mario Tumbarello
    Department of Infectious Diseases, Catholic University, Rome, Italy
    BMC Infect Dis 4:46. 2004
    ..Interestingly, older age did not seem to significantly affect the long-term virological outcome of HAART treated subjects...
  19. ncbi request reprint Older HIV-positive patients in the era of highly active antiretroviral therapy: changing of a scenario
    Mario Tumbarello
    Department of Infectious Diseases, Catholic University, Rome, Italy
    AIDS 17:128-31. 2003
  20. ncbi request reprint Risk factors and predictors of mortality of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia in HIV-infected patients
    Mario Tumbarello
    Department of Infectious Diseases and Microbiology, Catholic University, Largo A Gemelli 8, 00168 Roma, Italy
    J Antimicrob Chemother 50:375-82. 2002
    ..To define the incidence, risk factors and short-term predictors of mortality of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia in HIV-infected patients...
  21. ncbi request reprint Anti-retroviral therapy with protease inhibitors decreases virulence enzyme expression in vivo by Candida albicans without selection of avirulent fungus strains or decreasing their anti-mycotic susceptibility
    Flavia De Bernardis
    Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome 00161, Italy
    FEMS Immunol Med Microbiol 41:27-34. 2004
    ..While further demonstrating that HIV-PI inhibit Sap expressions, our results do not support the view that the mentioned inhibition could eliminate Candida or its selection of the oral cavity...
  22. ncbi request reprint Risk scoring and bloodstream infections
    Evelina Tacconelli
    Istituto Malattie Infettive, Universita Cattolica S Cuore, Rome, Italy
    Int J Antimicrob Agents 30:S88-92. 2007
    ..New randomised clinical trials are needed to study the efficacy of clinical scores in reducing BSI-associated morbidity and mortality...
  23. ncbi request reprint How could we reduce antibiotic use in critically ill patients?
    Giulia De Angelis
    Department of Infectious Diseases, Universita Cattolica, Largo F Vito 1, 00168 Rome, Italy
    Infect Disord Drug Targets 11:376-83. 2011
    ..To optimize antibiotic use in the ICU and to fight against the spread of resistance, it is extremely important to adopt a multifaceted approach including ASP...
  24. ncbi request reprint Increased soluble markers of endothelial dysfunction in HIV-positive patients under highly active antiretroviral therapy
    Katleen de Gaetano Donati
    Department of Infectious Diseases, Catholic University, Rome, Italy
    AIDS 17:765-8. 2003
  25. ncbi request reprint Azole susceptibility patterns and genetic relationship among oral Candida strains isolated in the era of highly active antiretroviral therapy
    Evelina Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    J Acquir Immune Defic Syndr 31:38-44. 2002
    ..Our findings demonstrate that most cases of HIV-associated OPC observed in the HAART era are caused by azole-susceptible strains. The reversion of an isolate from azole resistant to azole susceptible is related to strain replacement...
  26. pmc In vivo emergence of tigecycline resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli
    Teresa Spanu
    Institute of Microbiology, Catholic University, Rome, Italy
    Antimicrob Agents Chemother 56:4516-8. 2012
    ..The reported limited experience underlines the risk of occurrence of a tigecycline MIC increase under treatment pressure...
  27. ncbi request reprint Changes in incidence and risk factors of Mycobacterium avium complex infections in patients with AIDS in the era of new antiretroviral therapies
    M Tumbarello
    Department of Infectious Diseases, Catholic University, Rome, Italy
    Eur J Clin Microbiol Infect Dis 20:498-501. 2001
    ..These results indicate that MAC infections, although considerably less frequent in the HAART era, are still responsible for cases of severe disease...
  28. doi request reprint Detrimental clinical interaction between ritonavir-boosted protease inhibitors and vinblastine in HIV-infected patients with Hodgkin's lymphoma
    Antonella Cingolani
    Institute of Infectious Diseases, Catholic University, Rome, Italy
    AIDS 24:2408-12. 2010
    ....
  29. ncbi request reprint Hospital-acquired candidemia in HIV-infected patients. Incidence, risk factors and predictors of outcome
    S Bertagnolio
    Department of Infectious Diseases, Catholic University Medical School, Rome, Italy
    J Chemother 16:172-8. 2004
    ..Despite the use of HAART, this disease still represents a severe complication of advanced stage of AIDS...
  30. ncbi request reprint Morbidity associated with central venous catheter-use in a cohort of 212 hospitalized subjects with HIV infection
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    J Hosp Infect 44:186-92. 2000
    ..01); 2) low number of circulating CD4+ cells (P = 0.04); 3) high APACHE III score (P = 0. 04). Doctors responsible for AIDS patients should carefully consider the relative risks and benefits of CVC insertion in an individual patient...
  31. ncbi request reprint Correlation between cidofovir-associated uveitis and failing immunorestoration during HAART
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    Eur J Clin Microbiol Infect Dis 22:114-7. 2003
    ..Thus, cidofovir-associated uveitis seems to occur more frequently in AIDS patients with retinitis in whom highly active antiretroviral therapy fails to restore immunity...
  32. ncbi request reprint Impact of highly active antiretroviral therapy (HAART) on the incidence of bacterial infections in HIV-infected subjects
    K de Gaetano Donati
    Dept Infectious Diseases, Catholic University, L go A Gemelli 8, 00168 Rome, Italy
    J Chemother 15:60-5. 2003
    ..This study establishes that a significant reduction in bacterial infection incidence occurred in HIV-infected subjects when HAART became the standard therapy for HIV infection...
  33. ncbi request reprint Nosocomial bacterial pneumonia in human immunodeficiency virus infected subjects: incidence, risk factors and outcome
    M Tumbarello
    Dept of Infectious Diseases, Catholic University, Rome, Italy
    Eur Respir J 17:636-40. 2001
    ..Although the incidence of nosocomial bacterial pneumonia, as well of other opportunistic infections, decreased considerably in the era of highly active antiretroviral therapy, it still represents an important cause of mortality...
  34. doi request reprint Epidemiology, medical outcomes and costs of catheter-related bloodstream infections in intensive care units of four European countries: literature- and registry-based estimates
    E Tacconelli
    Department of Infectious Diseases, Catholic University, Rome, Italy
    J Hosp Infect 72:97-103. 2009
    ..9 to euro163.9 million associated costs. Discrepancies are mainly explained by the heterogeneous quality of epidemiological studies, as well as the variety of national clinical practices...
  35. doi request reprint Surgical site infections in HIV-infected patients: results from an Italian prospective multicenter observational study
    C M J Drapeau
    2nd Infectious Diseases Division, National Institute for Infectious Diseases, L Spallanzani, Via Portuense 292, 00149, Rome, Italy
    Infection 37:455-60. 2009
    ..The aim of this study was to determine the incidence and the associated risk factors for SSI in HIV-infected patients...
  36. ncbi request reprint Recurrent venous thrombosis in a patient with haemophilia A and HIV infection
    Katleen de Gaetano Donati
    Dept Infectious Diseases, Catholic University, Largo A Gemelli, 8, 00168 Rome, Italy
    Haematologica 87:ECR04. 2002
  37. ncbi request reprint Antiretroviral therapy with protease inhibitors has an early, immune reconstitution-independent beneficial effect on Candida virulence and oral candidiasis in human immunodeficiency virus-infected subjects
    Antonio Cassone
    Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, 00161 Rome, Italy
    J Infect Dis 185:188-95. 2002
    ..Thus, PIs exert an early, immune reconstitution-independent effect on Candida virulence in the oral cavities of HIV-positive subjects...
  38. pmc Multidrug-resistant Pseudomonas aeruginosa bloodstream infections: analysis of trends in prevalence and epidemiology
    Evelina Tacconelli
    Emerg Infect Dis 8:220-1. 2002
  39. ncbi request reprint Epidemiological comparison of true methicillin-resistant and methicillin-susceptible coagulase-negative staphylococcal bacteremia at hospital admission
    Evelina Tacconelli
    Beth Israel Deaconess Medical Center and Division of Infectious Diseases, Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 37:644-9. 2003
    ....
  40. ncbi request reprint Mupirocin prophylaxis to prevent Staphylococcus aureus infection in patients undergoing dialysis: a meta-analysis
    Evelina Tacconelli
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Clin Infect Dis 37:1629-38. 2003
    ..Mupirocin prophylaxis substantially reduces the rate of S. aureus infection in the dialysis population. Optimal regimens that minimize the emergence of mupirocin resistance need to be explored...
  41. ncbi request reprint Preventing the influx of vancomycin-resistant enterococci into health care institutions, by use of a simple validated prediction rule
    Evelina Tacconelli
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Clin Infect Dis 39:964-70. 2004
    ..The goal of this study was to develop a validated prediction rule for identification of patients harboring vancomycin-resistant enterococci (VRE) at hospital admission...
  42. ncbi request reprint Prediction of bacteremia using TREAT, a computerized decision-support system
    Mical Paul
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    Clin Infect Dis 42:1274-82. 2006
    ..Prediction of bloodstream infection at the time of sepsis onset allows one to make appropriate and economical management decisions...
  43. ncbi request reprint Benefit of appropriate empirical antibiotic treatment: thirty-day mortality and duration of hospital stay
    Abigail Fraser
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel
    Am J Med 119:970-6. 2006
    ..We evaluated the effect of inappropriate antibiotic treatment on mortality and duration of hospital stay in medical inpatients with bacterial infections...
  44. ncbi request reprint The TREAT project: decision support and prediction using causal probabilistic networks
    Leonard Leibovici
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel
    Int J Antimicrob Agents 30:S93-102. 2007
    ..In the present review we discuss the advantages of using causal probabilistic models for prediction and decision support, and the various decisions that were taken in the TREAT project...
  45. ncbi request reprint Improving empirical antibiotic treatment using TREAT, a computerized decision support system: cluster randomized trial
    Mical Paul
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, 49100 Petah Tiqva, Israel
    J Antimicrob Chemother 58:1238-45. 2006
    ..Appropriate antibiotic treatment decreases mortality, while superfluous treatment is associated with antibiotic resistance. We built a computerized decision support system for antibiotic treatment (TREAT) targeting these outcomes...
  46. ncbi request reprint Metallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues
    Giuseppe Cornaglia
    Department of Pathology, University of Verona, Italy
    Int J Antimicrob Agents 29:380-8. 2007
    ....
  47. ncbi request reprint The importance of addressing multidrug resistance and not assuming single-drug resistance in case-control studies
    Erika M C D'Agata
    Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Infect Control Hosp Epidemiol 27:670-4. 2006
    ....
  48. ncbi request reprint Prediction of specific pathogens in patients with sepsis: evaluation of TREAT, a computerized decision support system
    Mical Paul
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel
    J Antimicrob Chemother 59:1204-7. 2007
    ..Prediction of bacterial infections and their pathogens allows for early, directed investigation and treatment. We assessed the ability of TREAT, a computerized decision support system, to predict specific pathogens...