A Mordente

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. doi request reprint Anthracyclines and mitochondria
    Alvaro Mordente
    Institute of Biochemistry and Clinical Biochemistry, Catholic University School of Medicine, Rome, Italy
    Adv Exp Med Biol 942:385-419. 2012
  2. ncbi request reprint Lycopene and cardiovascular diseases: an update
    A Mordente
    Institute of Biochemistry and Clinical Biochemistry, Catholic University School of Medicine, Rome, Italy
    Curr Med Chem 18:1146-63. 2011
  3. ncbi request reprint New developments in anthracycline-induced cardiotoxicity
    A Mordente
    Institute of Biochemistry and Clinical Biochemistry, Catholic University School of Medicine, 00168 Roma, Italy
    Curr Med Chem 16:1656-72. 2009
  4. ncbi request reprint Effect of homocysteine on polymorphonuclear leukocyte activity and luminol-dependent chemiluminescence
    B Zappacosta
    Istituto di Chimica e Chimica Clinica, and CNR Centro Chimica dei Recettori, Universita Cattolica, Rome, Italy
    Luminescence 15:257-60. 2000
  5. ncbi request reprint Human heart cytosolic reductases and anthracycline cardiotoxicity
    A Mordente
    Institute of Biological Chemistry, Catholic University School of Medicine, Rome, Italy
    IUBMB Life 52:83-8. 2001
  6. ncbi request reprint Antioxidant properties of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (idebenone)
    A Mordente
    Institute of Biological Chemistry, Catholic University School of Medicine, Rome, Italy
    Chem Res Toxicol 11:54-63. 1998
  7. ncbi request reprint Is homocysteine a pro-oxidant?
    B Zappacosta
    Instituto di Chimica e Chimica Clinica, CNR Centro Chimica dei Recettori Università Cattolica, Rome, Italy
    Free Radic Res 35:499-505. 2001
  8. ncbi request reprint High total antioxidant activity and uric acid in tracheobronchial aspirate fluid of preterm infants during oxidative stress: an adaptive response to hyperoxia?
    G Vento
    Department of Pediatrics, Universita Cattolica del Sacro Cuore, Rome, Italy
    Acta Paediatr 89:336-42. 2000
  9. ncbi request reprint The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-1 in cytosolic fractions from human myocardium
    G Minotti
    Department of Pharmacology, Catholic University School of Medicine, Rome, Italy
    FASEB J 12:541-52. 1998
  10. ncbi request reprint Oxidative stress in ischemia-reperfusion injury: assessment by three independent biochemical markers
    S Rigattieri
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Ital Heart J 1:68-72. 2000

Detail Information

Publications12

  1. doi request reprint Anthracyclines and mitochondria
    Alvaro Mordente
    Institute of Biochemistry and Clinical Biochemistry, Catholic University School of Medicine, Rome, Italy
    Adv Exp Med Biol 942:385-419. 2012
    ..Here, we review the potential role of mitochondria in the molecular mechanisms underlying anthracyclines anticancer activity as well as in the pathogenesis of anthracycline-induced cardiotoxicity...
  2. ncbi request reprint Lycopene and cardiovascular diseases: an update
    A Mordente
    Institute of Biochemistry and Clinical Biochemistry, Catholic University School of Medicine, Rome, Italy
    Curr Med Chem 18:1146-63. 2011
    ....
  3. ncbi request reprint New developments in anthracycline-induced cardiotoxicity
    A Mordente
    Institute of Biochemistry and Clinical Biochemistry, Catholic University School of Medicine, 00168 Roma, Italy
    Curr Med Chem 16:1656-72. 2009
    ....
  4. ncbi request reprint Effect of homocysteine on polymorphonuclear leukocyte activity and luminol-dependent chemiluminescence
    B Zappacosta
    Istituto di Chimica e Chimica Clinica, and CNR Centro Chimica dei Recettori, Universita Cattolica, Rome, Italy
    Luminescence 15:257-60. 2000
    ....
  5. ncbi request reprint Human heart cytosolic reductases and anthracycline cardiotoxicity
    A Mordente
    Institute of Biological Chemistry, Catholic University School of Medicine, Rome, Italy
    IUBMB Life 52:83-8. 2001
    ....
  6. ncbi request reprint Antioxidant properties of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (idebenone)
    A Mordente
    Institute of Biological Chemistry, Catholic University School of Medicine, Rome, Italy
    Chem Res Toxicol 11:54-63. 1998
    ..We would therefore propose that the neuroprotective effects of idebenone can be attributed, at least in part, to its ability to function as an antioxidant, involving redox cycling between hydroquinone and quinone...
  7. ncbi request reprint Is homocysteine a pro-oxidant?
    B Zappacosta
    Instituto di Chimica e Chimica Clinica, CNR Centro Chimica dei Recettori Università Cattolica, Rome, Italy
    Free Radic Res 35:499-505. 2001
    ..All these results should, in our opinion, lead to a rethinking of the commonly held view that homocysteine oxidation is one of the main causative mechanisms of cardiovascular damage...
  8. ncbi request reprint High total antioxidant activity and uric acid in tracheobronchial aspirate fluid of preterm infants during oxidative stress: an adaptive response to hyperoxia?
    G Vento
    Department of Pediatrics, Universita Cattolica del Sacro Cuore, Rome, Italy
    Acta Paediatr 89:336-42. 2000
    ....
  9. ncbi request reprint The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-1 in cytosolic fractions from human myocardium
    G Minotti
    Department of Pharmacology, Catholic University School of Medicine, Rome, Italy
    FASEB J 12:541-52. 1998
    ..These results may also provide a guideline to design new drugs that mitigate the cardiotoxicity of DOX...
  10. ncbi request reprint Oxidative stress in ischemia-reperfusion injury: assessment by three independent biochemical markers
    S Rigattieri
    Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
    Ital Heart J 1:68-72. 2000
    ....
  11. ncbi request reprint Inhibition of salivary enzymes by cigarette smoke and the protective role of glutathione
    B Zappacosta
    Istituto di Biochimica e Biochimica Clinica, CNR Centro Chimica dei Recettori, Universita Cattolica del Sacro Cuore, Rome, Italy
    Hum Exp Toxicol 21:7-11. 2002
    ..Our results emphasize that not only one cigarette is sufficient to impair the salivary enzymatic activities but also strengthen the proposed protective role of GSH against the noxious biochemical effects of CS...
  12. ncbi request reprint The secondary alcohol and aglycone metabolites of doxorubicin alter metabolism of human erythrocytes
    F Misiti
    Istituto di Biochimica e Biochimica Clinica, Facolt di Medicina e Chirurgia, Universit Cattolica del Sacro Cuore, Rome, Italy
    Braz J Med Biol Res 36:1643-51. 2003
    ..On the basis of the results obtained in the present study, a new hypothesis, involving doxorubicinol and aglycone metabolites, has been proposed to clarify the mechanisms responsible for the doxorubicin-induced red blood cell toxicity...