F Landi

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. doi request reprint Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Clin Nutr 31:652-8. 2012
  2. pmc Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study
    Matteo Cesari
    Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Roma, Italy
    BMC Geriatr 8:34. 2008
  3. ncbi request reprint Insulin-like growth factor-binding protein 3 and hemoglobin concentration in older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Int J Hematol 85:294-9. 2007
  4. ncbi request reprint Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial
    Francesco Landi
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Ann Intern Med 139:635-41. 2003
  5. ncbi request reprint Impact of inappropriate drug use on physical performance among a frail elderly population living in the community
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:791-9. 2007
  6. pmc Antithrombotic drugs in secondary stroke prevention among a community dwelling older population
    F Landi
    Department of Gerontology, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, 00168 Rome, Italy
    J Neurol Neurosurg Psychiatry 74:1100-4. 2003
  7. ncbi request reprint Anemia status, hemoglobin concentration, and mortality in nursing home older residents
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    J Am Med Dir Assoc 8:322-7. 2007
  8. ncbi request reprint HDL-cholesterol and physical performance: results from the ageing and longevity study in the sirente geographic area (ilSIRENTE Study)
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Age Ageing 36:514-20. 2007
  9. ncbi request reprint Non-steroidal anti-inflammatory drug (NSAID) use and Alzheimer disease in community-dwelling elderly patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of the Sacred Heart, Rome, Italy
    Am J Geriatr Psychiatry 11:179-85. 2003
  10. ncbi request reprint Effects of influenza vaccination on mortality among frail, community-living elderly patients: an observational study
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric Medicine, Catholic University of the Sacred Heart, Roma, Italy
    Aging Clin Exp Res 15:254-8. 2003

Detail Information

Publications91

  1. doi request reprint Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Clin Nutr 31:652-8. 2012
    ..Sarcopenia has been indicated as a reliable marker of frailty and poor prognosis among the oldest individuals. We evaluated the relationship between sarcopenia and 2-year risk of falls in a population of persons aged 80 years or older...
  2. pmc Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study
    Matteo Cesari
    Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Roma, Italy
    BMC Geriatr 8:34. 2008
    ..Aim of the present study is to compare the predictive value for mortality of measures of physical function and SRH status, and test their possible interactions...
  3. ncbi request reprint Insulin-like growth factor-binding protein 3 and hemoglobin concentration in older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Int J Hematol 85:294-9. 2007
    ..This finding suggests that the growth hormone/IGF axis may play an important role in hematopoiesis, and it may be implicated in the age-related decline in hemoglobin concentration...
  4. ncbi request reprint Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial
    Francesco Landi
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Ann Intern Med 139:635-41. 2003
    ..Management options for pressure ulcers include local wound care; surgical repair; and, more recently, topical application of growth factors...
  5. ncbi request reprint Impact of inappropriate drug use on physical performance among a frail elderly population living in the community
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:791-9. 2007
    ..The aim of the present study was to evaluate the relationship between the use of inappropriate drugs and measures of physical performance, muscle strength and functional status in an elderly population (80+ years)...
  6. pmc Antithrombotic drugs in secondary stroke prevention among a community dwelling older population
    F Landi
    Department of Gerontology, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, 00168 Rome, Italy
    J Neurol Neurosurg Psychiatry 74:1100-4. 2003
    ..Patients who suffer a cerebrovascular event are at high risk of a recurrence. Secondary prevention is crucial in reducing the burden of cerebrovascular disease...
  7. ncbi request reprint Anemia status, hemoglobin concentration, and mortality in nursing home older residents
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    J Am Med Dir Assoc 8:322-7. 2007
    ..Anemia status is a typical feature of the "frailty syndrome" of elderly subjects. Increasing evidences suggest that low hemoglobin concentration is common in elderly subjects and adversely affects morbidity and mortality...
  8. ncbi request reprint HDL-cholesterol and physical performance: results from the ageing and longevity study in the sirente geographic area (ilSIRENTE Study)
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Age Ageing 36:514-20. 2007
    ..We evaluate the relationship of HDL-cholesterol with measures of physical performance, muscle strength, and functional status in older persons aged 80years or older...
  9. ncbi request reprint Non-steroidal anti-inflammatory drug (NSAID) use and Alzheimer disease in community-dwelling elderly patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of the Sacred Heart, Rome, Italy
    Am J Geriatr Psychiatry 11:179-85. 2003
    ..The aim of the present study was to examine the relationship between NSAIDs use and AD in a large sample of community-dwelling elderly people...
  10. ncbi request reprint Effects of influenza vaccination on mortality among frail, community-living elderly patients: an observational study
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric Medicine, Catholic University of the Sacred Heart, Roma, Italy
    Aging Clin Exp Res 15:254-8. 2003
    ..The aims of the present study were to describe the prevalence of vaccination against influenza in a population of older people living in the community, and to examine the relationship between influenza vaccination and mortality...
  11. ncbi request reprint Physical activity prevented functional decline among frail community-living elderly subjects in an international observational study
    Francesco Landi
    Department of Gerontology Geriatric, Catholic University Sacred Heart, Rome, Italy
    J Clin Epidemiol 60:518-24. 2007
    ..The aims of the study were to describe the prevalence of physical activity in a sample of older adults in home care in Europe and to examine the relationship between physical activity and incident disability...
  12. ncbi request reprint Physical activity and mortality in frail, community-living elderly patients
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 59:833-7. 2004
    ..The authors describe the prevalence of moderate-intensity physical activity in a population of older persons living in the community. In addition, they explore the relationship between physical activity and mortality...
  13. ncbi request reprint In a prospective observational study, influenza vaccination prevented hospitalization among older home care patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, 00168 Rome, Italy
    J Clin Epidemiol 59:1072-7. 2006
    ..The aim of the study is (1) to describe the prevalence of vaccination against influenza in older home care patients and (2) to investigate the protective effect of influenza vaccination for hospitalization events...
  14. ncbi request reprint Functional decline in frail community-dwelling stroke patients
    F Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Eur J Neurol 13:17-23. 2006
    ..Appropriate post-acute rehabilitation programs and adequate home care interventions focused on the prevention and treatment of these conditions might be correlated to better outcomes in older post-stroke patients...
  15. ncbi request reprint Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study
    Francesco Landi
    Department of Gerontology Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:622-6. 2005
    ..Although a small number of falls have a single cause, the majority have many different causes resulting from the interactions between intrinsic or extrinsic risk factors...
  16. ncbi request reprint Prevalence and predictors of influenza vaccination among frail, community-living elderly patients: an international observational study
    Francesco Landi
    Department of Gerontology Geriatric, Catholic University Sacred Heart, Rome, Italy
    Vaccine 23:3896-901. 2005
    ..In conclusion, more than 40% of subjects in this sample of home care patients in Europe did not receive influenza vaccination. Recommendations for influenza vaccination have not been adequately implemented...
  17. ncbi request reprint Anticholinergic drugs and physical function among frail elderly population
    F Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Clin Pharmacol Ther 81:235-41. 2007
    ..Our results suggest that among old-old subjects the use of anticholinergic drugs is associated with impaired physical performance and functional status...
  18. ncbi request reprint Free insulin-like growth factor-I and cognitive function in older persons living in community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, 00168, Roma, Italy
    Growth Horm IGF Res 17:58-66. 2007
    ..Increasing evidences from experimental and human studies suggest that the activity of the growth hormone (GH/insulin-like growth factor-I) axis may contribute to the age-related cognitive decline and poor cognition in late life...
  19. ncbi request reprint Comorbidity and social factors predicted hospitalization in frail elderly patients
    Francesco Landi
    Instituto di Medicina Interna e Geriatria, Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Clin Epidemiol 57:832-6. 2004
    ....
  20. ncbi request reprint Indwelling urethral catheter and mortality in frail elderly women living in community
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Neurourol Urodyn 23:697-701. 2004
    ..The aims of present study were to describe the prevalence of bladder catheter in a population of older women living in community and to examine the relationship between urinary catheter and mortality...
  21. ncbi request reprint The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Aging Clin Exp Res 17:486-93. 2005
    ....
  22. ncbi request reprint Serum high-density lipoprotein cholesterol levels and mortality in frail, community-living elderly
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 54:71-8. 2008
    ..High-density lipoprotein (HDL) cholesterol has been hypothesized to be a reliable marker of frailty and poor prognosis among the oldest elderly...
  23. ncbi request reprint Benzodiazepines and the risk of urinary incontinence in frail older persons living in the community
    Francesco Landi
    Department of Gerontology Geriatrics and Physiatrics, Catholic University of Sacred Heart, Rome, Italy
    Clin Pharmacol Ther 72:729-34. 2002
    ..The aim of this study was to estimate the risk of urinary incontinence associated with the use of oxidative or nonoxidative benzodiazepines...
  24. ncbi request reprint Minimum data set for home care: a valid instrument to assess frail older people living in the community
    F Landi
    Istituto di Medicina Interna e Geriatria, Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Med Care 38:1184-90. 2000
    ..To facilitate comprehensive assessment, as well as to generate a useful, policy-relevant patient database, standardized, multidimensional, and validated instruments are very helpful...
  25. ncbi request reprint Body mass index and mortality among hospitalized patients
    F Landi
    Istituto di Medicina Interna e Geriatria, Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168 Rome, Italy
    Arch Intern Med 160:2641-4. 2000
    ..However, the effect of age on excess mortality from all causes associated with obesity is controversial. The aim of the present study is to determine the effect of age on the relationship between BMI and mortality...
  26. ncbi request reprint A new model of integrated home care for the elderly: impact on hospital use
    F Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Clin Epidemiol 54:968-70. 2001
    ..In conclusion, an integrated home care program based on the implementation of a comprehensive geriatric assessment instrument guided by a case manager has a significant impact on hospitalization and is cost-effective...
  27. ncbi request reprint Physical activity and risk of cognitive impairment among older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Aging Clin Exp Res 19:410-6. 2007
    ..The aim of the present study was to evaluate the relationship of lifetime physical activity with cognitive performance in older persons aged 80 years or older...
  28. ncbi request reprint Effects of anorexia on mortality among older adults receiving home care: an observation study
    F Landi
    Department of Gerontology Geriatric and Medicine Rehabilitative, Catholic University of Sacred Heart, Rome, Italy
    J Nutr Health Aging 16:79-83. 2012
    ..We describe the prevalence of secondary anorexia in a population of older people living in community and receiving home care. In addition, we examined the relationship between secondary anorexia and mortality...
  29. doi request reprint Anorexia, physical function, and incident disability among the frail elderly population: results from the ilSIRENTE study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    J Am Med Dir Assoc 11:268-74. 2010
    ..The aim of the present study was to evaluate the relationship between anorexia of aging and measures of physical performance, muscle strength, and functional status in older persons aged 80 years or older...
  30. ncbi request reprint Predictors of rehabilitation outcomes in frail patients treated in a geriatric hospital
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Am Geriatr Soc 50:679-84. 2002
    ..To evaluate the effect of medical indicators of health status on functional gain during rehabilitation of frail older patients...
  31. doi request reprint Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Clin Nutr 29:441-7. 2010
    ..We evaluated the relationship between midarm muscle circumference (MAMC) and physical performance, muscle strength, functional status and survival in persons aged 80 years or older...
  32. doi request reprint Disability, more than multimorbidity, was predictive of mortality among older persons aged 80 years and older
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Clin Epidemiol 63:752-9. 2010
    ..In this study, we evaluate the impact of disability and multimorbidity on the risk of all-cause death in a population of frail older persons living in community...
  33. ncbi request reprint Pain management in frail, community-living elderly patients
    F Landi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Largo Agostino Gemelli, 8, 00168 Rome, Italy
    Arch Intern Med 161:2721-4. 2001
    ..Pain is a common problem among older people living in different community settings. As indicated by the World Health Organization (WHO), pain can be relieved using pharmacologic agents. However, pain continues to be addressed inadequately...
  34. doi request reprint Daily pain and functional decline among old-old adults living in the community: results from the ilSIRENTE Study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of the Sacred Heart, Rome, Italy
    J Pain Symptom Manage 38:350-7. 2009
    ..94; 95% CI: 2.00-23.01). In conclusion, among very old subjects living in the community, moderate to severe daily pain is associated with a significant increased risk of disability, irrespective of potential confounders...
  35. doi request reprint Walking one hour or more per day prevented mortality among older persons: results from ilSIRENTE study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Prev Med 47:422-6. 2008
    ..The aim of the present study was to explore the relationship between regular walking and the risk of all-cause death in a large population of frail and very old people living in community...
  36. ncbi request reprint Prevalence, clinical correlates, and treatment of hypertension in elderly nursing home residents. SAGE (Systematic Assessment of Geriatric Drug Use via Epidemiology) Study Group
    G Gambassi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    Arch Intern Med 158:2377-85. 1998
    ..Hypertension is prevalent in the elderly, but an information gap remains regarding the old, frail, individuals with complex conditions living in long-term care...
  37. ncbi request reprint Functional status and clinical correlates in cognitively impaired community-living older people
    F Landi
    Istituto di Medicina Interna e Geriatria, Centro di Medicina dell'Invecchiamento, , Rome, Italy
    J Geriatr Psychiatry Neurol 14:21-7. 2001
    ..The present findings support the possibility that severe cognitive impairment has an independent effect on survival...
  38. pmc Randomised trial of impact of model of integrated care and case management for older people living in the community
    R Bernabei
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, 00168 Rome, Italy
    BMJ 316:1348-51. 1998
    ..To evaluate the impact of a programme of integrated social and medical care among frail elderly people living in the community...
  39. ncbi request reprint Impact of a new assessment system, the MDS-HC, on function and hospitalization of homebound older people: a controlled clinical trial
    F Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Am Geriatr Soc 49:1288-93. 2001
    ..CONCLUSIONS: The MDS-HC assessment instrument may provide a cost-saving approach to reducing institutionalization and functional decline in older people living in the community...
  40. pmc Lifetime occupation and physical function: a prospective cohort study on persons aged 80 years and older living in a community
    A Russo
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Occup Environ Med 63:438-42. 2006
    ..Several studies have reported predictors for loss of mobility and impairments of physical performance among frail elderly people...
  41. ncbi request reprint Trends in antihypertensive drugs in the elderly: the decline of thiazides
    G Onder
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Hum Hypertens 15:291-7. 2001
    ..A possible explanation is that the choice to prescribe a thiazides diuretic is influenced by age, functional status and comorbidity...
  42. ncbi request reprint Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    Matteo Cesari
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:24-32. 2006
    ..Physical function measures have gained increased importance in the evaluation of older persons. The presence of comorbidity is a major and growing issue in geriatrics...
  43. ncbi request reprint Depression and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE Study)
    Andrea Russo
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    J Geriatr Psychiatry Neurol 20:131-7. 2007
    ..In conclusion, physical performance and functional status measures are significantly and negatively influenced by the presence of depression in community-dwelling older persons aged 80 years and older...
  44. ncbi request reprint Non malignant daily pain and risk of disability among older adults in home care in Europe
    Manuel Soldato
    Department of Gerontology, Catholic University of Sacred Heart, Roma, Italy
    Pain 129:304-10. 2007
    ..36; 95% CI: 1.05-1.78). The risk of disability increased with pain severity and with number of painful sites. In conclusion among old subjects living in the community, daily pain is associated with an increased risk of disability...
  45. doi request reprint Heart failure and adverse drug reactions among hospitalized older adults
    C Catananti
    Department of Geriatrics, Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Clin Pharmacol Ther 86:307-10. 2009
    ..58; 95% CI 1.22-2.05) but not in the men (OR 0.99; 95% CI 0.74-1.34). In conclusion, HF appears to be associated with a higher rate of ADRs among hospitalized patients. Gender may influence the effect of HF on the risk of ADRs...
  46. ncbi request reprint Dose-related impact of alcohol consumption on cognitive function in advanced age: results of a multicenter survey
    G Zuccala
    Department of Gerontology, Catholic University of Rome, Italy
    Alcohol Clin Exp Res 25:1743-8. 2001
    ..We assessed the association between alcohol consumption and cognitive impairment in a series of older subjects enrolled in a multicenter pharmacoepidemiology survey...
  47. ncbi request reprint Pressure ulcer and mortality in frail elderly people living in community
    F Landi
    Department of Gerontology Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Arch Gerontol Geriatr 44:217-23. 2007
    ..92; 95% cl 1.52-2.43)...
  48. ncbi request reprint A model for integrated home care of frail older patients: the Silver Network project. SILVERNET-HC Study Group
    F Landi
    Institute of Internal Medicine and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Aging (Milano) 11:262-72. 1999
    ....
  49. ncbi request reprint Validity of diagnostic and drug data in standardized nursing home resident assessments: potential for geriatric pharmacoepidemiology. SAGE Study Group. Systematic Assessment of Geriatric drug use via Epidemiology
    G Gambassi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    Med Care 36:167-79. 1998
    ..The authors sought to ascertain reliability and validity of diagnostic and drug data in a database obtained by merging the Minimum Data Set with detailed information on drugs consumed by each resident...
  50. pmc Predictors of mortality in patients with Alzheimer's disease living in nursing homes
    G Gambassi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Neurol Neurosurg Psychiatry 67:59-65. 1999
    ..To identify factors associated with mortality in patients with Alzheimer's disease, and to evaluate whether these factors vary according to severity of cognitive impairment...
  51. ncbi request reprint Patient depression and caregiver attitudes: results from The AgeD in HOme Care study
    Manuel Soldato
    Department of Gerontology, Catholic University of Sacred Heart, Roma, Italy
    J Affect Disord 106:107-15. 2008
    ..The present cross-sectional study was aimed to evaluate the association between care recipient depression and caregiver attitudes...
  52. doi request reprint GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)
    Ettore Capoluongo
    Institute of Biochemistry and Clinical Biochemistry, Catholic University of Sacred Heart, Roma, Italy
    Clin Chim Acta 399:92-6. 2009
    ..This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years)...
  53. ncbi request reprint Second and third generation assessment instruments: the birth of standardization in geriatric care
    Roberto Bernabei
    Centro Medicina dell Invecchiamento CEMI, Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Gerontol A Biol Sci Med Sci 63:308-13. 2008
    ....
  54. doi request reprint Myeloperoxidase levels and mortality in frail community-living elderly individuals
    Silvia Giovannini
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 65:369-76. 2010
    ....
  55. ncbi request reprint Validated treatments and therapeutics prospectives regarding pharmacological products for sarcopenia
    G Onder
    Department of Geriatrics, Policlinico A Gemelli, Catholic University of the Sacred Heart, Rome, Italy
    J Nutr Health Aging 13:746-56. 2009
    ....
  56. ncbi request reprint Depression and adverse drug reactions among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168 Rome, Italy
    Arch Intern Med 163:301-5. 2003
    ..The aim of this study was to assess whether depression may be a risk factor for adverse drug reactions (ADRs) among hospitalized older adults...
  57. ncbi request reprint Effects of an occupational therapy program on functional outcomes in older stroke patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:85-91. 2006
    ..Objective: To evaluate the efficacy of occupational therapy programs in patients with a recent stroke...
  58. doi request reprint Case management, preventive strategies, and caregiver attitudes among older adults in home care: results of the ADHOC study
    Graziano Onder
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    J Am Med Dir Assoc 9:337-41. 2008
    ..We hypothesized that such an approach may also result in a higher rate of use of preventive strategies and lower caregiver distress...
  59. doi request reprint Vitamin D receptor polymorphisms and falls among older adults living in the community: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Bone Miner Res 23:1031-6. 2008
    ..Further studies conducted in larger population are needed to confirm the association of BsmI genotype and falls and to understand reasons for these findings...
  60. ncbi request reprint Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    Graziano Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 50:1962-8. 2002
    ....
  61. ncbi request reprint Health care for older persons in Italy
    Roberto Bernabei
    Department of Gerontology Geriatrics and Physiatrics, Catholic University of the Sacred Heart, Roma, Italy
    Aging Clin Exp Res 14:247-51. 2002
    ....
  62. ncbi request reprint Prevalence and risk factors for falls in an older community-dwelling population
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatric Sciences, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 57:M722-6. 2002
    ..The aim of this study was to determine the prevalence of falls and related intrinsic and extrinsic risk factors in a community-dwelling older population...
  63. doi request reprint Predictors of rehabilitation outcome among frail elderly patients living in the community
    Domenico Fusco
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, Rome, Italy
    J Am Med Dir Assoc 10:335-41. 2009
    ..The purpose of this study is to evaluate the association of medical indicators of health status on functional recovery during rehabilitation of frail elderly living in the community...
  64. pmc All-cause mortality associated with atypical and conventional antipsychotics among nursing home residents with dementia: a retrospective cohort study
    Rosa Liperoti
    Centro di Medicina dell Invecchiamento, Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Largo A Gemelli, 8 0168 Rome, Italy
    J Clin Psychiatry 70:1340-7. 2009
    ..We conducted a retrospective cohort study to compare the risk of death associated with atypical and conventional antipsychotics in a large population of nursing home residents with dementia...
  65. doi request reprint Distress of caregivers of older adults receiving home care in European countries: results from the AgeD in HOme Care Study
    Graziano Onder
    Department of Gerontology, Catholic University of Sacred Heart, Roma, Italy
    Am J Geriatr Psychiatry 17:899-906. 2009
    ..To identify factors associated with distress of caregivers of home care patients in Europe and to assess whether caregivers response to distress varies among countries...
  66. ncbi request reprint Adverse drug reactions and cognitive function among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Eur J Clin Pharmacol 58:371-7. 2002
    ..To explore the relationship between cognitive function and the detection of adverse drug reactions (ADRs) and to evaluate whether cognitive function could influence the association between age and ADRs...
  67. ncbi request reprint Association of calcium channel blocker use and pregnancy-associated plasma protein-A among older adults with hypertension: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Italy
    J Gerontol A Biol Sci Med Sci 62:1274-8. 2007
    ..The aim of the present cross-sectional study was to evaluated if, among older hypertensive adults, PAPP-A levels differ according to use of CCB...
  68. ncbi request reprint Chewing problems and mortality in older adults in home care: results from the Aged in Home Care study
    Graziano Onder
    Department of Gerontology, Catholic University Sacred Heart, Rome, Italy
    J Am Geriatr Soc 55:1961-6. 2007
    ..To assess the association between chewing problems and risk of mortality in an older population receiving home care in Europe...
  69. ncbi request reprint Total serum cholesterol and recovery from disability among hospitalized older adults
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 61:736-42. 2006
    ..The objective of the present study was to determine within a cohort of acutely hospitalized disabled elderly patients whether total cholesterol predicts recovery from disability in basic activities of daily living (ADL)...
  70. ncbi request reprint Association between daily pain and physical function among old-old adults living in the community: results from the ilSIRENTE study
    Graziano Onder
    Department of Gerontology, Catholic University of Sacred Heart, Rome, Italy
    Pain 121:53-9. 2006
    ..In conclusion, the present study shows that among old-old subjects living in the community, daily pain is highly prevalent and that this condition is associated with impaired muscle strength and physical performance...
  71. ncbi request reprint Association between pain and depression among older adults in Europe: results from the Aged in Home Care (AdHOC) project: a cross-sectional study
    Graziano Onder
    Department of Gerontologic Science, Catholic University of the Sacred Heart, Rome, Italy
    J Clin Psychiatry 66:982-8. 2005
    ..To assess the association between pain and depression in a population of older adults...
  72. ncbi request reprint Impact of inappropriate drug use among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168, Roma, Italy
    Eur J Clin Pharmacol 61:453-9. 2005
    ..The objective of this study was to evaluate the impact of inappropriate drug use on all-cause mortality, adverse drug reactions (ADRs) and length of stay among in-hospital patients...
  73. ncbi request reprint Body mass index, free insulin-like growth factor I, and physical function among older adults: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Am J Physiol Endocrinol Metab 291:E829-34. 2006
    ..By contrast, no association was observed between IGFBP-3 and study outcomes, independently of BMI. In conclusion, high IGF-I level is associated with better physical function in older persons with obesity, but not in nonobese subjects...
  74. ncbi request reprint Use of ACE inhibitors is associated with elevated levels of IGFBP-3 among hypertensive older adults: results from the IlSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:389-95. 2007
    ..However, this relationship has only rarely been investigated in humans. The aim of the present cross-sectional study was to assess the association of ACE inhibitors with free IGF-1 and IGFBP-3 in the blood of older hypertensive adults...
  75. ncbi request reprint Case management and risk of nursing home admission for older adults in home care: results of the AgeD in HOme Care Study
    Graziano Onder
    Department of Gerontology, Catholic University Sacred Heart, Rome, Italy
    J Am Geriatr Soc 55:439-44. 2007
    ..To explore the relationship between a case management approach and the risk of institutionalization in a large European population of frail, old people in home care...
  76. ncbi request reprint Depression and risk of nursing home admission among older adults in home care in Europe: results from the Aged in Home Care (AdHOC) study
    Graziano Onder
    Department of Gerontology, Catholic University of Sacred Heart, Rome, Italy
    J Clin Psychiatry 68:1392-8. 2007
    ..The aim of the present study was to assess the effect of depression on the risk of nursing home admission in a group of older adults receiving home care in Europe...
  77. ncbi request reprint Potentially reversible risk factors and urinary incontinence in frail older people living in community
    Francesco Landi
    Institute of Internal Medicine, Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, I 00168 Rome, Italy
    Age Ageing 32:194-9. 2003
    ..However, few data exist concerning the potentially reversible causes of this condition among frail community-dwelling older individuals...
  78. ncbi request reprint Serum cholesterol levels and in-hospital mortality in the elderly
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Am J Med 115:265-71. 2003
    ..We explored whether total cholesterol levels were independently associated with in-hospital mortality among elderly patients...
  79. ncbi request reprint Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168, Roma, Italy
    Eur J Clin Pharmacol 59:157-62. 2003
    ..To determine the prevalence of inappropriate medication use among hospitalized older adults and to identify predictors of this use...
  80. ncbi request reprint Omega-3 polyunsaturated fatty acids and depression: a review of the evidence
    R Liperoti
    Centro di Medicina dell Invecchiamento, Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Rome, Italy
    Curr Pharm Des 15:4165-72. 2009
    ..Further studies with larger sample sizes and more sophisticated design are required to provide convincing evidence of a causal relationship between omega-3 PUFA and depression...
  81. ncbi request reprint Physical restraint and subcutaneous hematoma in an anticoagulated patient
    F Landi
    Institute of Internal Medicine and Geriatrics, Center of Gerontology, Catholic University of Sacred Heart, Rome, Italy
    South Med J 94:254-5. 2001
    ..Accordingly, they should systematically check for hemorrhagic complications and attempt to limit the use of such devices...
  82. ncbi request reprint Pain and its relation to depressive symptoms in frail older people living in the community: an observational study
    Francesco Landi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Pain Symptom Manage 29:255-62. 2005
    ..Treatment models that put together the assessment and the treatment of both pain and depression are indispensable for better outcomes...
  83. doi request reprint Moving against frailty: does physical activity matter?
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Biogerontology 11:537-45. 2010
    ....
  84. ncbi request reprint Skin tolerability and efficacy of combination therapy with hydrogen peroxide stabilized cream and adapalene gel in comparison with benzoyl peroxide cream and adapalene gel in common acne. A randomized, investigator-masked, controlled trial
    R Capizzi
    Clinica Dermatologica, Policlinico Universitario Agostino Gemelli, Rome, Italy
    Br J Dermatol 151:481-4. 2004
    ..A previous clinical study has shown that HP cream monotherapy presents a better skin tolerability in comparison with BP in patients with mild AV...
  85. ncbi request reprint Occupational therapy for stroke patients: when, where, and how?
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of the Sacred Heart, Rome, Italy
    Stroke 34:676-87. 2003
  86. ncbi request reprint Nursing home case-mix instruments: validation of the RUG-III system in Italy
    Enrico Brizioli
    Gruppo S Stefano, Healthcare Services, Potenza Picena MC, Universita Cattolica S Cuore, Roma, Italy
    Aging Clin Exp Res 15:243-53. 2003
    ....
  87. ncbi request reprint Cross-sectional association between behavioral symptoms and potential elder abuse among subjects in home care in Italy: results from the Silvernet Study
    Luciana Ogioni
    Geriatrics Sector, Federal University of Rio de Janeiro UFRJ, Home for Ageing of Aeron√°utica, Rio de Janeiro, Brazil
    Am J Geriatr Psychiatry 15:70-8. 2007
    ..The objectives of this study were to evaluate the prevalence of potential elder abuse among older adults receiving home care and to assess the association between behavioral symptoms and potential abuse...
  88. ncbi request reprint Moderate alcohol consumption and adverse drug reactions among older adults
    Graziano Onder
    Section of Gerontology and Geriatrics, Sticht Center on Aging, Wake Forest University, Baptist Medical Center, Winston Salem, NC, USA
    Pharmacoepidemiol Drug Saf 11:385-92. 2002
    ..To assess the effect of moderate alcohol consumption on Adverse Drug Reactions (ADRs) among older adults admitted to acute care hospitals and to examine the consistency of this effect across gender and age groups...
  89. ncbi request reprint Impact of hospitalization on blood pressure control in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
    Graziano Onder
    Section of Gerontology and Geriatrics, Stricht Center on Aging, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    Pharmacotherapy 23:240-7. 2003
    ..To evaluate whether hospitalization affects blood pressure control in hypertensive patients, and to identify factors associated with attainment of adequate blood pressure control and with aggressive pharmacologic treatment...
  90. ncbi request reprint Physical function, physical activity and recent falls. Results from the "Invecchiamento e Longevità nel Sirente (ilSIRENTE)" Study
    Irene Mangani
    Department of Critical Care Medicine and Surgery, Unit of Geriatric Medicine, University of Florence, Florence, Italy
    Aging Clin Exp Res 20:234-41. 2008
    ....
  91. ncbi request reprint Fellowships for geriatric study in Italy
    Graziano Onder
    Aging Clin Exp Res 18:462. 2006