Elisa Gremese

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. doi request reprint Obesity and reduction of the response rate to anti-tumor necrosis factor α in rheumatoid arthritis: an approach to a personalized medicine
    Elisa Gremese
    Catholic University of the Sacred Heart, Rome, Italy
    Arthritis Care Res (Hoboken) 65:94-100. 2013
  2. ncbi request reprint The metabolic syndrome: the crossroads between rheumatoid arthritis and cardiovascular risk
    Elisa Gremese
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    Autoimmun Rev 10:582-9. 2011
  3. pmc B-cell subsets in the joint compartments of seropositive and seronegative rheumatoid arthritis (RA) and No-RA arthritides express memory markers and ZAP70 and characterize the aggregate pattern irrespectively of the autoantibody status
    Alessandro Michelutti
    Division of Rheumatology, Catholic University of Sacred Heart, Rome, Italy
    Mol Med 17:901-9. 2011
  4. doi request reprint ZAP-70+ B cell subset influences response to B cell depletion therapy and early repopulation in rheumatoid arthritis
    Elisa Gremese
    Division of Rheumatology, Institute of Rheumatology and Affine Sciences IRSA, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    J Rheumatol 39:2276-85. 2012
  5. pmc Biomarkers of good EULAR response to the B cell depletion therapy in all seropositive rheumatoid arthritis patients: clues for the pathogenesis
    Gianfranco Ferraccioli
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    PLoS ONE 7:e40362. 2012
  6. pmc Very early rheumatoid arthritis is the major predictor of major outcomes: clinical ACR remission and radiographic non-progression
    Silvia Bosello
    Division of Rheumatology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Ann Rheum Dis 70:1292-5. 2011
  7. ncbi request reprint Body weight, gender and response to TNF-α blockers in axial spondyloarthritis
    Elisa Gremese
    Institute of Rheumatology and Affine Sciences, Division of Rheumatology, Catholic University of the Sacred Heart, CIC Via Moscati 31, 00168, Rome, Italy
    Rheumatology (Oxford) 53:875-81. 2014
  8. doi request reprint Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis
    Gaetano Zizzo
    Department of Rheumatology, Catholic University of the Sacred Heart, CIC, Via Moscati 31, 00168, Rome, Italy
    Clin Immunol 138:107-16. 2011
  9. pmc ACR70-disease activity score remission achievement from switches between all the available biological agents in rheumatoid arthritis: a systematic review of the literature
    Stefano Alivernini
    Division of Rheumatology, School of Medicine, Catholic University of the Sacred Heart, Largo F Vito 1, 00168 Rome, Italy
    Arthritis Res Ther 11:R163. 2009
  10. doi request reprint Clinical and ultrasonographic remission determines different chances of relapse in early and long standing rheumatoid arthritis
    Giusy Peluso
    Division of Rheumatology, UCSC Catholic University of Rome, Complesso Integrato Columbus CIC, Rome, Italy
    Ann Rheum Dis 70:172-5. 2011

Collaborators

Detail Information

Publications27

  1. doi request reprint Obesity and reduction of the response rate to anti-tumor necrosis factor α in rheumatoid arthritis: an approach to a personalized medicine
    Elisa Gremese
    Catholic University of the Sacred Heart, Rome, Italy
    Arthritis Care Res (Hoboken) 65:94-100. 2013
    ....
  2. ncbi request reprint The metabolic syndrome: the crossroads between rheumatoid arthritis and cardiovascular risk
    Elisa Gremese
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    Autoimmun Rev 10:582-9. 2011
    ..To obtain a full control of the CV risk, data suggest that it is therefore mandatory a "tight control" of both RA and MetS inflammations...
  3. pmc B-cell subsets in the joint compartments of seropositive and seronegative rheumatoid arthritis (RA) and No-RA arthritides express memory markers and ZAP70 and characterize the aggregate pattern irrespectively of the autoantibody status
    Alessandro Michelutti
    Division of Rheumatology, Catholic University of Sacred Heart, Rome, Italy
    Mol Med 17:901-9. 2011
    ..CD27(+)/IgD(-)/ZAP70(+) memory B cells accumulate preferentially in the joints of RA, suggesting a dynamic maturation of the B cells in this compartment...
  4. doi request reprint ZAP-70+ B cell subset influences response to B cell depletion therapy and early repopulation in rheumatoid arthritis
    Elisa Gremese
    Division of Rheumatology, Institute of Rheumatology and Affine Sciences IRSA, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    J Rheumatol 39:2276-85. 2012
    ....
  5. pmc Biomarkers of good EULAR response to the B cell depletion therapy in all seropositive rheumatoid arthritis patients: clues for the pathogenesis
    Gianfranco Ferraccioli
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    PLoS ONE 7:e40362. 2012
    ....
  6. pmc Very early rheumatoid arthritis is the major predictor of major outcomes: clinical ACR remission and radiographic non-progression
    Silvia Bosello
    Division of Rheumatology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Ann Rheum Dis 70:1292-5. 2011
    ..To identify predictors of clinical remission as well as of no x-ray progression in a cohort of early rheumatoid arthritis (ERA) treated with a tight-control protocol...
  7. ncbi request reprint Body weight, gender and response to TNF-α blockers in axial spondyloarthritis
    Elisa Gremese
    Institute of Rheumatology and Affine Sciences, Division of Rheumatology, Catholic University of the Sacred Heart, CIC Via Moscati 31, 00168, Rome, Italy
    Rheumatology (Oxford) 53:875-81. 2014
    ..The objective of this study was to determine whether BMI and gender could lead to a different response rate to anti-TNF agents in patients affected by axial SpA...
  8. doi request reprint Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis
    Gaetano Zizzo
    Department of Rheumatology, Catholic University of the Sacred Heart, CIC, Via Moscati 31, 00168, Rome, Italy
    Clin Immunol 138:107-16. 2011
    ..The TCR-zeta(dim) lymphocytes in SF were found to produce the highest amounts of cytokines including IL-17, whereas no ZAP-70 impairment was associated to Th17...
  9. pmc ACR70-disease activity score remission achievement from switches between all the available biological agents in rheumatoid arthritis: a systematic review of the literature
    Stefano Alivernini
    Division of Rheumatology, School of Medicine, Catholic University of the Sacred Heart, Largo F Vito 1, 00168 Rome, Italy
    Arthritis Res Ther 11:R163. 2009
    ....
  10. doi request reprint Clinical and ultrasonographic remission determines different chances of relapse in early and long standing rheumatoid arthritis
    Giusy Peluso
    Division of Rheumatology, UCSC Catholic University of Rome, Complesso Integrato Columbus CIC, Rome, Italy
    Ann Rheum Dis 70:172-5. 2011
    ....
  11. pmc Very early rheumatoid arthritis as a predictor of remission: a multicentre real life prospective study
    Elisa Gremese
    Rheumatology Division, Catholic University of the Sacred Heart, Rome, Italy
    Ann Rheum Dis 72:858-62. 2013
    ....
  12. doi request reprint Longterm retention of tumor necrosis factor-α inhibitor therapy in a large italian cohort of patients with rheumatoid arthritis from the GISEA registry: an appraisal of predictors
    Florenzo Iannone
    Universita Cattolica del Sacro Cuore, Rome, Italy
    J Rheumatol 39:1179-84. 2012
    ..To evaluate 4-year retention rates of tumor necrosis factor-α (TNF-α) inhibitors adalimumab, etanercept, and infliximab among patients with longstanding rheumatoid arthritis (RA), as derived from an Italian national registry...
  13. doi request reprint Synovial B cells of rheumatoid arthritis express ZAP-70 which increases the survival and correlates with the inflammatory and autoimmune phenotype
    Barbara Tolusso
    Division of Rheumatology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Clin Immunol 131:98-108. 2009
    ..ZAP-70 positive B cells seem to define a subset characterized by increased survival and high relationship with local inflammation and autoimmunity...
  14. ncbi request reprint Diagnostic performance of anti-citrullinated peptide antibodies for the diagnosis of rheumatoid arthritis: the relevance of likelihood ratios
    Donatello Pietrapertosa
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    Clin Chem Lab Med 48:829-34. 2010
    ..The goal of our study was to evaluate the diagnostic performance of the anti-cyclic citrullinated peptide 2 (anti-CCP2) assay in patients with autoimmune and inflammatory disorders...
  15. doi request reprint Residual minimal disease activity in rheumatoid arthritis: a simple definition through an in-depth statistical analysis of the major outcome
    Donatello Pietrapertosa
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    Rheumatology (Oxford) 48:1242-6. 2009
    ..To obtain the simplest definition of minimal disease activity (MDA) and to compare it with published proposed definitions of MDA in patients with RA...
  16. ncbi request reprint Mononuclear cell response to lipopolysaccharide in patients with rheumatoid arthritis: relationship with tristetraprolin expression
    Martina Fabris
    Department of Rheumatology, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy
    J Rheumatol 32:998-1005. 2005
    ..To analyze tumor necrosis factor-alpha (TNF-alpha) synthesis by mononuclear cells stimulated with lipopolysaccharide (LPS) in patients with rheumatoid arthritis (RA)...
  17. pmc PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis
    Michele Ciro Totaro
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    PLoS ONE 6:e24292. 2011
    ..The aim of the study was to evaluate the association between the PTPN22 rs2476601 polymorphism and RA in Italian subjects and to compare our results with those of other European countries, carrying out a meta-analysis of European data...
  18. ncbi request reprint Rheumatoid arthritis and Alzheimer's disease: genetic and epigenetic links in inflammatory regulation
    Gianfranco Ferraccioli
    Division of Rheumatology, Institute of Rheumatology and Affine Sciences, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Discov Med 14:379-88. 2012
    ..In this review we will discuss the genetic and epigenetic regulation of the inflammatory cascade in RA and AD to find out the possible links between RA and AD onset...
  19. pmc Interleukin-1β and interleukin-6 in arthritis animal models: roles in the early phase of transition from acute to chronic inflammation and relevance for human rheumatoid arthritis
    Gianfranco Ferraccioli
    Division of Rheumatology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Mol Med 16:552-7. 2010
    ..In the other models, IL-1β and IL-6, more than TNF-α, appear to be relevant in driving the transition, which suggests that these should be the targets of an early intervention to stop the course toward the chronic form of the disease...
  20. doi request reprint Polymorphisms of the IgH enhancer HS1.2 and risk of systemic lupus erythematosus
    Domenico Frezza
    Laboratory of Genetics, Department of Biology Enrico Calef, University of Roma Tor Vergata, Rome, Italy
    Ann Rheum Dis 71:1309-15. 2012
    ....
  21. ncbi request reprint IL-1B and IL-1RN gene polymorphisms in rheumatoid arthritis: relationship with protein plasma levels and response to therapy
    Barbara Tolusso
    UCSC Catholic University of Rome, Division of Rheumatology, 00168 Rome, Italy
    Pharmacogenomics 7:683-95. 2006
    ..Also, to assess the influence of IL1-B and IL1RN gene polymorphism on IL-1beta/IL-1Ra plasma levels and response to therapy...
  22. ncbi request reprint B cell depletion may lead to normalization of anti-platelet, anti-erythrocyte and antiphospholipid antibodies in systemic lupus erythematosus
    Paolo Tomietto
    Division of Rheumatology, Catholic University of the Sacred Heart Rome UCSC, Rome, Italy
    Thromb Haemost 92:1150-3. 2004
  23. doi request reprint Adiposity, joint and systemic inflammation: the additional risk of having a metabolic syndrome in rheumatoid arthritis
    Gianfranco Ferraccioli
    Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy
    Swiss Med Wkly 141:w13211. 2011
    ....
  24. ncbi request reprint Thrombogenicity of TNF alpha in rheumatoid arthritis defined through biological probes: TNF alpha blockers
    Gianfranco Ferraccioli
    Division of Rheumatology, DPMSC, School of Medicine, University of Udine, Udine 33100, Italy
    Autoimmun Rev 3:261-6. 2004
    ....
  25. doi request reprint Should we consider tumor necrosis factor as the only target in spondyloarthritides?
    Gianfranco Ferraccioli
    Institute of Rheumatology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy
    J Rheumatol Suppl 89:94-6. 2012
    ..Immunohistological and functional data suggest that B cells, Th17, or IL-17A might be important, and indeed preliminary data concerning drugs targeting B cells and IL-17A seem to suggest clinical benefits...
  26. ncbi request reprint Hepatocyte growth factor and transforming growth factor beta1 ratio at baseline can predict early response to cyclophosphamide in systemic lupus erythematosus nephritis
    Anna Capuano
    Catholic University of Rome, Rome, Italy
    Arthritis Rheum 54:3633-9. 2006
    ....
  27. doi request reprint Pathogenetic, clinical and pharmaco-economic assessment in rheumatoid arthritis (RA)
    Gianfranco Ferraccioli
    Division of Rheumatology, Institute of Rheumatology, School of Medicine, Catholic University of the Sacred Heart CIC, Via Moscati 31, Rome, Italy
    Intern Emerg Med 6:11-5. 2011
    ..This is and should be the major aim in each RA patient...