G Addolorato

Summary

Affiliation: Catholic University
Country: Italy

Publications

  1. ncbi request reprint Regional cerebral hypoperfusion in patients with celiac disease
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University, Rome, Italy
    Am J Med 116:312-7. 2004
  2. doi request reprint Alcohol addiction: toward a patient-oriented pharmacological treatment
    Giovanni Addolorato
    Catholic University of Rome, Gemelli Hospital, Department of Internal Medicine, Largo Gemelli 8, 00168 Rome, Italy 39 06 30154334 39 06 35502775
    Expert Opin Pharmacother 14:2157-60. 2013
  3. doi request reprint Management of alcohol dependence in patients with liver disease
    Giovanni Addolorato
    Department of Internal Medicine, Institute of Internal Medicine, Catholic University of Rome, Gemelli Hospital, Largo Gemelli 8, 00168 Rome, Italy
    CNS Drugs 27:287-99. 2013
  4. ncbi request reprint Safety and efficacy of baclofen in the treatment of alcohol-dependent patients
    Giovanni Addolorato
    Institute of Internal Medicine Catholic University of Rome l go A Gemelli, 8 I 00168 Rome, Italy
    Curr Pharm Des 16:2113-7. 2010
  5. ncbi request reprint How many cravings? Pharmacological aspects of craving treatment in alcohol addiction: a review
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Neuropsychobiology 51:59-66. 2005
  6. doi request reprint Social phobia in coeliac disease
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Scand J Gastroenterol 43:410-5. 2008
  7. ncbi request reprint Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males
    Giovanni Addolorato
    Institutes of Internal Medicine, Catholic University of Rome, L go A Gemelli 8, I 00168, Rome, Italy
    Appetite 50:50-6. 2008
  8. doi request reprint Insulin but not insulin growth factor-1 correlates with craving in currently drinking alcohol-dependent patients
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol Clin Exp Res 32:450-8. 2008
  9. doi request reprint Role of trait anxiety in persistent radicular pain after surgery for lumbar disc herniation: a 1-year longitudinal study
    Cristina D'Angelo
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Neurosurgery 67:265-71. 2010
  10. ncbi request reprint Psychological support counselling improves gluten-free diet compliance in coeliac patients with affective disorders
    G Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Aliment Pharmacol Ther 20:777-82. 2004

Detail Information

Publications93

  1. ncbi request reprint Regional cerebral hypoperfusion in patients with celiac disease
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University, Rome, Italy
    Am J Med 116:312-7. 2004
    ..Because of a case report that cerebral hypoperfusion in a celiac patient resolved after a gluten-free diet, we studied brain perfusion changes in untreated celiac patients, treated celiac patients, and healthy controls...
  2. doi request reprint Alcohol addiction: toward a patient-oriented pharmacological treatment
    Giovanni Addolorato
    Catholic University of Rome, Gemelli Hospital, Department of Internal Medicine, Largo Gemelli 8, 00168 Rome, Italy 39 06 30154334 39 06 35502775
    Expert Opin Pharmacother 14:2157-60. 2013
    ..The development of new effective and safe pharmacological agents to treat alcoholic patients is crucial, together with the need to identify predictors of outcomes in different subsets of patients. ..
  3. doi request reprint Management of alcohol dependence in patients with liver disease
    Giovanni Addolorato
    Department of Internal Medicine, Institute of Internal Medicine, Catholic University of Rome, Gemelli Hospital, Largo Gemelli 8, 00168 Rome, Italy
    CNS Drugs 27:287-99. 2013
    ..To date, baclofen represents the only anti-craving medication formally tested in a randomized clinical trial in alcoholic patients affected by liver cirrhosis, although additional confirmatory studies are warranted...
  4. ncbi request reprint Safety and efficacy of baclofen in the treatment of alcohol-dependent patients
    Giovanni Addolorato
    Institute of Internal Medicine Catholic University of Rome l go A Gemelli, 8 I 00168 Rome, Italy
    Curr Pharm Des 16:2113-7. 2010
    ..In summary, baclofen represents a safe and effective medication to treat alcohol dependence, thus holding promise as a new pharmacotherapy. However, large studies are needed to confirm the present findings...
  5. ncbi request reprint How many cravings? Pharmacological aspects of craving treatment in alcohol addiction: a review
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Neuropsychobiology 51:59-66. 2005
    ..In this review, the main drugs currently used in the treatment of patients with alcohol problems are described. A hypothesis of pharmacological treatment of the different types of craving is also discussed...
  6. doi request reprint Social phobia in coeliac disease
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Scand J Gastroenterol 43:410-5. 2008
    ..Although social phobia is included among the anxiety disorders, its presence in CD has never been investigated. The aim of the present study was to evaluate social phobia in CD patients...
  7. ncbi request reprint Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males
    Giovanni Addolorato
    Institutes of Internal Medicine, Catholic University of Rome, L go A Gemelli 8, I 00168, Rome, Italy
    Appetite 50:50-6. 2008
    ..Finally, short-term moderate ethanol intake appeared to influence the FM, although it was not able to significantly affect nutritional or body composition...
  8. doi request reprint Insulin but not insulin growth factor-1 correlates with craving in currently drinking alcohol-dependent patients
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol Clin Exp Res 32:450-8. 2008
    ..The aim of this clinical study was to evaluate the relationships between insulin and IGF-1 plasma concentrations and alcohol craving...
  9. doi request reprint Role of trait anxiety in persistent radicular pain after surgery for lumbar disc herniation: a 1-year longitudinal study
    Cristina D'Angelo
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Neurosurgery 67:265-71. 2010
    ..To evaluate anxiety and depression as prognostic factors for radicular and back pain after surgery in patients with lumbar disc herniation in a 1-year follow-up study...
  10. ncbi request reprint Psychological support counselling improves gluten-free diet compliance in coeliac patients with affective disorders
    G Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Aliment Pharmacol Ther 20:777-82. 2004
    ..Anxiety and depression are common features of coeliac disease. Depression is cause of non-compliance to treatment in chronic illness...
  11. doi request reprint Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Largo A Gemelli 8, I 00168 Rome, Italy
    Alcohol Alcohol 46:312-7. 2011
    ..To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence...
  12. doi request reprint State and trait anxiety and depression in patients affected by gastrointestinal diseases: psychometric evaluation of 1641 patients referred to an internal medicine outpatient setting
    G Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Int J Clin Pract 62:1063-9. 2008
    ..To evaluate state and trait form of anxiety and current depression in patients affected by gastrointestinal diseases...
  13. doi request reprint Role of the GABA(B) receptor system in alcoholism and stress: focus on clinical studies and treatment perspectives
    Giovanni Addolorato
    Institute of Internal Medicine, Agostino Gemelli Hospital, Catholic University of Rome, Rome, Italy
    Alcohol 43:559-63. 2009
    ..e., cirrhosis). Future studies should investigate which alcoholic subtype may better benefit of the administration of baclofen in the treatment of alcohol dependence...
  14. ncbi request reprint Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Lancet 370:1915-22. 2007
    ..We aimed to investigate the effectiveness and safety of baclofen in achieving and maintaining alcohol abstinence in patients with liver cirrhosis...
  15. ncbi request reprint Baclofen: a new drug for the treatment of alcohol dependence
    G Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Int J Clin Pract 60:1003-8. 2006
    ..The efficacy of the drug in the management of both alcohol withdrawal syndrome and relapse prevention should entail a vastly simplified pharmacotherapy of alcohol dependence...
  16. ncbi request reprint The therapeutic potential of gamma-hydroxybutyric acid for alcohol dependence: balancing the risks and benefits. A focus on clinical data
    Giovanni Addolorato
    Catholic University of Rome, Institute of Internal Medicine, L o A Gemelli 8, I 00168 Rome, Italy
    Expert Opin Investig Drugs 18:675-86. 2009
    ..Finally, GHB and naltrexone combined together represent a possible approach deserving future investigations...
  17. ncbi request reprint Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Am J Med 119:276.e13-8. 2006
    ..Accordingly, the present study was designed to compare efficacy, tolerability and safety of baclofen versus diazepam in the treatment of AWS...
  18. ncbi request reprint Hypokalemic nephropathy in an adult patient with partial empty sella: a classic Bartter's syndrome, a Gitelman's syndrome or both?
    G Addolorato
    Department of Internal Medicine, Catholic University of Rome, Rome, Italy
    Panminerva Med 48:137-42. 2006
    ....
  19. doi request reprint Hormones and drinking behaviour: new findings on ghrelin, insulin, leptin and volume-regulating hormones. An ESBRA Symposium report
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Largo A Gemelli 8, Rome, Italy
    Drug Alcohol Rev 28:160-5. 2009
    ..Accordingly, research on this topic could lead to possible development of new therapeutic approaches in the treatment of patients with alcohol problems...
  20. doi request reprint Affective and psychiatric disorders in celiac disease
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Dig Dis 26:140-8. 2008
    ..The available data suggest that screening for CD in patients with affective and/or psychiatric symptoms may be useful since these disorders could be the expression of an organic disease rather than primary psychiatric illnesses...
  21. ncbi request reprint Relationship between ghrelin levels, alcohol craving, and nutritional status in current alcoholic patients
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Largo A Gemelli 8, I 00168 Rome, Italy
    Alcohol Clin Exp Res 30:1933-7. 2006
    ..Alcohol-craving and food-seeking behavior could share common neural circuits. Ghrelin is related to nutritional status, but few data are available in alcoholic patients on the relationship between ghrelin and nutritional disorders...
  22. ncbi request reprint Analysis of the T1288R mutation of the Wilson disease ATP7B gene in four generations of a family: possible genotype-phenotype correlation with hepatic onset
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Gemelli Hospital, L go Gemelli 8, 00168, Rome, Italy
    Dig Dis Sci 52:2570-5. 2007
    ..Consequently, a genotype-phenotype correlation could be hypothesized, although further studies are necessary to clarify this topic...
  23. ncbi request reprint Oxygen free radical production in rat liver: dose-related effect of ethanol on reperfusion injury
    G Addolorato
    Patologia Medica and Medicina Interna, Catholic University of Rome, Italy
    Dig Dis Sci 46:1057-66. 2001
    ..The effect of ethanol on ischemia-reperfusion injury seems to be a dose-related response, with an additional toxic effect only at high doses of ethanol...
  24. ncbi request reprint Changes in body composition, substrate oxidation, and resting metabolic rate in adult celiac disease patients after a 1-y gluten-free diet treatment
    E Capristo
    Department of Internal Medicine, CNR Centro Fisiopatologia dello Shock, Universita Cattolica del Sacro Cuore, Rome, Italy
    Am J Clin Nutr 72:76-81. 2000
    ..The incidence of celiac disease has been on the rise in both Europe and the United States. Celiac disease patients are at high risk of undernutrition because of nutrient malabsorption...
  25. ncbi request reprint Gamma-hydroxybutyric acid (GHB) in the treatment of alcohol withdrawal syndrome: a randomized comparative study versus benzodiazepine
    G Addolorato
    Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
    Alcohol Clin Exp Res 23:1596-604. 1999
    ..The aim of the present randomized, controlled, single-blind study was to evaluate the efficacy and safety of GHB compared with diazepam in the treatment of AWS...
  26. ncbi request reprint Gamma-hydroxybutyric acid versus naltrexone in maintaining alcohol abstinence: an open randomized comparative study
    F Caputo
    Department of Internal Medicine, Cardioangiology and Hepatology, G Fontana Centre for the Study and Treatment of Alcohol Addiction, University of Bologna, Via Massarenti no 9, Bologna, 40138, Italy
    Drug Alcohol Depend 70:85-91. 2003
    ..The results of the present study show that GHB is more effective than NTX in maintaining abstinence from alcohol in a short-term treatment period; on the other hand, NTX confirmed its ability to reduce alcohol relapses...
  27. ncbi request reprint Anxiety but not depression decreases in coeliac patients after one-year gluten-free diet: a longitudinal study
    G Addolorato
    Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
    Scand J Gastroenterol 36:502-6. 2001
    ..At present, the role of a gluten-free diet (GFD) on psychological disorders is still poorly known. The aim of this study was to evaluate state and trait anxiety and depression in adult CD patients before and after 1 year of GFD...
  28. ncbi request reprint Effect of a vegetable-protein-rich polymeric diet treatment on body composition and energy metabolism in inactive Crohn's disease
    E Capristo
    Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
    Eur J Gastroenterol Hepatol 12:5-11. 2000
    ....
  29. doi request reprint Incidence of craving for and abuse of gamma-hydroxybutyric acid (GHB) in different populations of treated alcoholics: an open comparative study
    F Caputo
    G Fontana Centre for the Study and Multidisciplinary Treatment of Alcohol Addiction, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Bologna, Italy
    J Psychopharmacol 23:883-90. 2009
    ....
  30. ncbi request reprint Anhedonia and substance-related symptoms in detoxified substance-dependent subjects: a correlation study
    L Janiri
    Institute of Psychiatry and Psychology, Treatment Unit for Alcoholism and Multiple Drug Abuse, Catholic University, Rome, Italy
    Neuropsychobiology 52:37-44. 2005
    ..In conclusion, we found interrelations between hedonic capability, craving and protracted withdrawal, particularly in opiate-dependent subjects. The strongest association occurred between hedonic capability and craving...
  31. ncbi request reprint A new HPLC method for the direct analysis of triglycerides of dicarboxylic acids in biological samples
    E Capristo
    Istituto di Medicina Interna e Geriatria, Universita Cattolica S Cuore, Largo A Gemelli, 8 00168, Rome, Italy
    Clin Chim Acta 289:11-21. 1999
    ....
  32. ncbi request reprint Cutaneous manifestations in celiac disease
    L Abenavoli
    Institute of Internal Medicine, Catholic University, L go Gemelli 8, 00168 Rome, Italy
    World J Gastroenterol 12:843-52. 2006
    ..The opportunity to evaluate the possible presence of CD in patients affected by skin disorders is discussed...
  33. ncbi request reprint Marked decrease of serum Ca 125 levels after Denver shunt placement in a patient with cirrhosis and refractory ascites
    L Leggio
    Institute of Internal Medicine, Catholic University of Rome, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00168 Rome, Italy
    Dig Dis Sci 51:1644-6. 2006
  34. ncbi request reprint Baclofen efficacy in reducing alcohol craving and intake: a preliminary double-blind randomized controlled study
    Giovanni Addolorato
    Institute of Internal Medicine and Institute of Psychiatry, Catholic University of Rome, Rome, Italy
    Alcohol Alcohol 37:504-8. 2002
    ..The present study was aimed at providing a first evaluation of the efficacy of baclofen in inducing and maintaining abstinence and reducing craving for alcohol in alcohol-dependent patients in a double-blind placebo-controlled design...
  35. doi request reprint Is cortisol involved in the alcohol-related fat mass impairment? A longitudinal clinical study
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol Alcohol 44:211-5. 2009
    ..The goal of this study was to investigate if there is any relationship between HP-hormones and metabolic and nutritional parameters in alcoholic subjects...
  36. doi request reprint Renin and aldosterone but not the natriuretic peptide correlate with obsessive craving in medium-term abstinent alcohol-dependent patients: a longitudinal study
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol 42:375-81. 2008
    ..In conclusion, the renin-aldosterone axis could play a role in craving in medium-term abstinent patients and thereby leading to the hypothesis that alcohol craving could be influenced by the fluid volume intake...
  37. doi request reprint Baclofen in the treatment of persistent hiccup: a case series
    A Mirijello
    Department of Internal Medicine, Catholic University of Rome, Italy
    Int J Clin Pract 67:918-21. 2013
    ..Persistent hiccup is a worrying symptom both for patients, because of reduced quality of life, and for physicians, because of frustration for unsuccessful treatments...
  38. ncbi request reprint Evaluation of effects (symptoms and palatability) after ingestion of "Gran Soleil" in healthy volunteers
    G Gasbarrini
    Institute of Internal Medicine, Catholic University, Rome, Italy
    J Biol Regul Homeost Agents 22:201-5. 2008
    ..In conclusion, it is possible to suppose that a product with a good palatability, able to support and maintain a good digestive condition, derives from the mixture of digestive herbs, citrus juices, liquor and other ingredients...
  39. ncbi request reprint Wilson's disease: clinical, genetic and pharmacological findings
    L Leggio
    Institute of Internal Medicine, Catholic University of Rome, Italy
    Int J Immunopathol Pharmacol 18:7-14. 2005
    ..However the most appropriate therapy, including OLT, remains controversial in WD and further studies are needed especially in order to differentiate the possibility of specific therapies for different WD phenotypes...
  40. ncbi request reprint Metadoxine in the treatment of acute and chronic alcoholism: a review
    G Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Italy
    Int J Immunopathol Pharmacol 16:207-14. 2003
    ..In this review the preclinical and clinical results obtained using metadoxine in acute and chronic alcohol intoxication are reported...
  41. ncbi request reprint Serum leptin levels in post-hepatitis liver cirrhosis
    A V Greco
    Istituto di Medicina Interna e Geriatria, Catholic University, Rome, Italy
    J Hepatol 33:38-42. 2000
    ..The behaviour of serum leptin in patients with different Child-Pugh score, post-hepatitis liver cirrhosis and insulin sensitivity has therefore been investigated and compared with that in alcoholic Child C patients...
  42. doi request reprint Metabolic and nutritional features in adult celiac patients
    Noemi Malandrino
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Dig Dis 26:128-33. 2008
    ..Thus, an early and accurate evaluation of nutritional status and energy metabolism represents a fundamental tool in the management of CD patients...
  43. ncbi request reprint Coenzyme Q 10 and cardiovascular risk factors in idiopathic sudden sensorineural hearing loss patients
    Gabriella Cadoni
    Institute of Otorhinolaryngology, Catholic University of the Sacred Heart, Rome, Italy
    Otol Neurotol 28:878-83. 2007
    ..We investigated the association of idiopathic sudden sensorineural hearing loss (ISSNHL) with coenzyme Q (CoQ) and cardiovascular risk factors...
  44. doi request reprint Relationship between the hypothalamic-pituitary-thyroid axis and alcohol craving in alcohol-dependent patients: a longitudinal study
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol Clin Exp Res 32:2047-53. 2008
    ..Investigating this association in alcohol-dependent (AD) patients was the aim of this preliminary and exploratory study...
  45. doi request reprint Interaction of alcohol intake and cofactors on the risk of cirrhosis
    Tommaso Stroffolini
    Department of Infectious and Tropical Diseases, Policlinico Umberto I, Rome, Italy
    Liver Int 30:867-70. 2010
    ..Evaluation of the interaction between alcohol intake and cofactors [hepatitis B virus (HBV), hepatitis C virus (HCV), body mass index] and coffee consumption on the risk of cirrhosis...
  46. ncbi request reprint A new mutation of Wilson's disease P-type ATPase gene in a patient with cirrhosis and coombs-positive hemolytic anemia
    Lorenzo Leggio
    Institutes of Internal Medicine, Catholic University of Rome, Rome
    Dig Dis Sci 51:34-8. 2006
  47. doi request reprint Increased serum high-density lipoprotein-cholesterol concentration in celiac disease after gluten-free diet treatment correlates with body fat stores
    Esmeralda Capristo
    Department of Internal Medicine, Catholic University, Rome, Italy
    J Clin Gastroenterol 43:946-9. 2009
    ..We evaluated blood lipids and body composition in 26 CD patients with low HDL-C level (<1.0 mmol/L) at diagnosis and after GFD...
  48. ncbi request reprint Reduced plasma ghrelin concentration in celiac disease after gluten-free diet treatment
    Esmeralda Capristo
    Institute of Internal Medicine, Metabolic Unit, Catholic University, Rome, Italy
    Scand J Gastroenterol 40:430-6. 2005
    ....
  49. doi request reprint Baclofen promotes alcohol abstinence in alcohol dependent cirrhotic patients with hepatitis C virus (HCV) infection
    L Leggio
    Center for Alcohol and Addiction Studies, Brown University, Providence, RI 02912, USA
    Addict Behav 37:561-4. 2012
    ..e. albumin, INR) in alcohol-dependent HCV-infected cirrhotic patients. Baclofen may represent a clinically relevant alcohol pharmacotherapy for these patients...
  50. ncbi request reprint Gender affects reperfusion injury in rat liver
    A Gasbarrini
    Patologia Medica, Catholic University of Rome, Italy
    Dig Dis Sci 46:1305-12. 2001
    ..A greater susceptibility to reperfusion injury may be evoked as an alternative mechanism to explain the poor outcome of female organ after liver transplantation...
  51. ncbi request reprint Lymphoepithelioma-like carcinoma of the skin
    S Cavalieri
    Institute of Dermatology, Catholic University of the Sacred Heart, Rome, Italy
    Int J Immunopathol Pharmacol 20:851-4. 2007
    ..Lymphoepithelioma-like carcinoma of the skin is a malignant neoplasm which tends to relapse locally and has a moderate tendency to metastatize...
  52. ncbi request reprint Neuroendocrine and psychological assessment in a guinness 10 days scuba dive
    L Revelli
    Department of Endocrine Surgery, Catholic University of Rome, Rome, Italy
    Int J Sports Med 28:848-52. 2007
    ..No subject discontinued the diving due to occurred psychological disorders or systemic events. The present report shows that the long-term diving permanence is possible, at least in well trained scuba divers...
  53. ncbi request reprint Rapid suppression of alcohol withdrawal syndrome by baclofen
    Giovanni Addolorato
    Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
    Am J Med 112:226-9. 2002
  54. ncbi request reprint Association between migraine and Celiac disease: results from a preliminary case-control and therapeutic study
    Maurizio Gabrielli
    Department of Internal Medicine, Catholic University of the Sacred Heart, Gemelli Hospital, Rome, Italy
    Am J Gastroenterol 98:625-9. 2003
    ....
  55. doi request reprint State and trait anxiety and depression in patients with primary brain tumors before and after surgery: 1-year longitudinal study
    Cristina D'Angelo
    Institute of Internal Medicine, Catholic University of Rome, and Department of Cardiac Surgery, St Andrea Hospital, Rome, Italy
    J Neurosurg 108:281-6. 2008
    ..The relationships between these affective disorders and the patient's sex, tumor histology, and laterality of the tumor were also evaluated...
  56. ncbi request reprint Celiac disease in the 21st century: issues of under- and over-diagnosis
    G Gasbarrini
    Department of Internal Medicine, Catholic University of Rome, Rome, Italy
    Int J Immunopathol Pharmacol 22:1-7. 2009
    ....
  57. ncbi request reprint Evaluation of symptoms and palatability in healthy volunteers after ingestion of an iced dessert by using different flavours
    A Gallo
    Institute of Internal Medicine, Catholic University, Rome
    J Biol Regul Homeost Agents 23:127-31. 2009
    ....
  58. ncbi request reprint Comparing and combining gamma-hydroxybutyric acid (GHB) and naltrexone in maintaining abstinence from alcohol: an open randomised comparative study
    Fabio Caputo
    G Fontana Centre for the Study and Multidisciplinary Treatment of Alcohol Addiction, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Eur Neuropsychopharmacol 17:781-9. 2007
    ..The GHB/NTX combination was more effective than either drug given alone; this suggests that the two drugs combine their different actions synergistically without suppressing the favourable effects of each other...
  59. ncbi request reprint Short-term methadone administration reduces alcohol consumption in non-alcoholic heroin addicts
    F Caputo
    G Fontana Centre for the Study and Treatment of Alcohol Addiction, Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Via Massarenti n 9th, 40138 Bologna, Italy
    Alcohol Alcohol 37:164-8. 2002
    ..The results of the present study suggest a possible effect of short-term methadone administration in reducing alcohol consumption in a population of non-alcoholic heroin-addicted patients...
  60. doi request reprint Acute alcohol intoxication
    Luisa Vonghia
    Institute of Internal Medicine, Catholic University of Rome, Italy
    Eur J Intern Med 19:561-7. 2008
    ..In patients presenting an acute alcohol intoxication, alcohol-related disorders should be detected so that the patient can be directed to an alcohol treatment unit, where a personalized, specific treatment can be established...
  61. ncbi request reprint Neurobiochemical and clinical aspects of craving in alcohol addiction: a review
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome, Gemelli Hospital, Largo A Gemelli 8, 00168 Rome, Italy
    Addict Behav 30:1209-24. 2005
    ....
  62. ncbi request reprint Evaluation of the albumin-gamma-glutamyltransferase isoenzyme as a diagnostic marker of hepatocellular carcinoma-complicating liver cirrhosis
    Maurizio Pompili
    Department of Internal Medicine and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gastroenterol Hepatol 18:288-95. 2003
    ..The present study aimed to evaluate the usefulness of albumin-gamma-glutamyltransferase isoenzyme in the diagnosis of hepatocellular carcinoma...
  63. ncbi request reprint Suppression of craving for gamma-hydroxybutyric acid by naltrexone administration: three case reports
    Fabio Caputo
    G Fontana Centre for the Study and Multidisciplinary Treatment of Alcohol Addiction, Department of Internal Medicine, Cardioangiology and Hepatology, Alma Mater Studiorum, University of Bologna, Bologna, Italy
    Clin Neuropharmacol 28:87-9. 2005
    ..A combined therapy with GHB and NTX seems to be able to suppress craving for the former, thus improving the manageability and safety of treatment...
  64. ncbi request reprint Rapid regression of psoriasis in a coeliac patient after gluten-free diet. A case report and review of the literature
    Giovanni Addolorato
    Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
    Digestion 68:9-12. 2003
    ..However, at present the relationship between CD and psoriasis remains controversial since there are few and contrasting data on this topic...
  65. ncbi request reprint Suppression of alcohol delirium tremens by baclofen administration: a case report
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of the Sacred Heart, Gemelli Hospital, Largo A Gemelli 8, 00168 Rome, Italy
    Clin Neuropharmacol 26:258-62. 2003
    ..Here, we report a case of DT successfully treated with baclofen. This result indicates that the efficacy of baclofen in the treatment of DT should be examined in future clinical trials...
  66. ncbi request reprint Coeliac disease and hearing loss: preliminary data on a new possible association
    Lorenzo Leggio
    Institutes of Internal Medicine, Catholic University of Rome, Rome, Italy
    Scand J Gastroenterol 42:1209-13. 2007
    ..At present, no data are available on the presence of hearing loss disorder in coeliac patients. The aim of the present study was to investigate the prevalence of hearing loss in coeliac patients compared with that in healthy controls...
  67. ncbi request reprint Superior vena cava thrombosis treated by angioplasty and stenting in a cirrhotic patient with peritoneovenous shunt
    Lorenzo Leggio
    Institutes of Internal Medicine, Catholic University of Rome, Rome, Italy
    Ann Thorac Cardiovasc Surg 14:60-2. 2008
    ..The patient died in June 2006 due to severe liver function impairment and hepato-renal syndrome. The present case shows that percutaneous transluminal angioplasty represents a good choice for primary intervention...
  68. ncbi request reprint The Italian version of the Obsessive-Compulsive Drinking Scale: validation, comparison with the other versions, and difference between type 1- and type 2-like alcoholics
    Luigi Janiri
    Treatment Unit for Alcoholism and Multiple Substance Abuse, Institute of Psychiatry and Psychology, Catholic University of the Sacred Heart, Rome, Italy
    Drug Alcohol Depend 74:187-95. 2004
    ....
  69. doi request reprint Understanding and treating patients with alcoholic cirrhosis: an update
    Giovanni Addolorato
    Institute of Internal Medicine, Catholic University of Rome GA, LL, Rome, Italy
    Alcohol Clin Exp Res 33:1136-44. 2009
    ..All together the information available suggests the need of a multimodal approach in the clinical management of these patients...
  70. doi request reprint Serotonin transporter (SERT) brain density and neurobiological Cloninger subtypes model: a lesson by human autoradiography studies
    Lorenzo Leggio
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Alcohol Alcohol 43:148-50. 2008
    ..New developments in the neurobiological understanding of subtypes of alcoholic patients, could led to get the basis for a more personalized pharmacological therapy...
  71. doi request reprint Complementary therapies for treating alcoholism First Annual meeting by Complementary Medicine Research Group of the Italian Society for Alcohol Studies-May 5, 2006, Florence, Italy
    Ludovico Abenavoli
    Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
    Fitoterapia 79:142-7. 2008
  72. ncbi request reprint Role of GABA(B) receptor in alcohol dependence: reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics
    Giancarlo Colombo
    C N R Institute of Neuroscience, University of Cagliari, Viale Diaz, 182, I 09126 Cagliari, Italy
    Neurotox Res 6:403-14. 2004
    ..In both clinical studies, baclofen was well tolerated with minimal side effects. These results suggest that baclofen may represent a potentially effective medication in the treatment of alcohol-dependent patients...
  73. ncbi request reprint Psychological support counseling: a new strategy to increase gluten-free diet compliance in celiac patients
    Lorenzo Leggio
    Am J Gastroenterol 100:1424-5. 2005
  74. ncbi request reprint Tolerance to baclofen's sedative effect in alcohol-addicted patients: no dissipation after a period of abstinence
    Giovanni Addolorato
    Psychopharmacology (Berl) 178:351-2. 2005
  75. ncbi request reprint Baclofen-induced reduction of alcohol reinforcement in alcohol-preferring rats
    Paola Maccioni
    Bernard B Brodie Department of Neuroscience, University of Cagliari, Viale Diaz 182, I 09126 Cagliari, Italy
    Alcohol 36:161-8. 2005
    ..These data are also in agreement with the results of recent preliminary clinical studies suggesting that baclofen may have therapeutic efficacy in the treatment of alcohol dependence...
  76. ncbi request reprint Baclofen for outpatient treatment of alcohol withdrawal syndrome
    Giovanni Addolorato
    J Fam Pract 54:24. 2005
  77. ncbi request reprint Celiac disease and skin disorders
    Lorenzo Leggio
    Pediatr Dermatol 22:376-7. 2005
  78. ncbi request reprint Wilson's disease
    Lorenzo Leggio
    Lancet 369:902. 2007
  79. ncbi request reprint Baclofen suppresses alcohol intake and craving for alcohol in a schizophrenic alcohol-dependent patient: a case report
    Roberta Agabio
    J Clin Psychopharmacol 27:319-20. 2007
  80. ncbi request reprint Neurologic disorders in patients with celiac disease: are they mediated by brain perfusion changes?
    Ludovico Abenavoli
    Pediatrics 114:1734; author reply 1734. 2004
  81. doi request reprint Celiac disease
    Cristina D'Angelo
    N Engl J Med 358:747; author reply 748-9. 2008
  82. ncbi request reprint Metadoxine in acute alcohol intoxication: a double-blind, randomized, placebo-controlled study
    Leonid S Shpilenya
    Narcological County Dispensary, Vasyleostrovsky District 4 th, Line V 0 2 3 2 5, St Petersburg, Russia
    Alcohol Clin Exp Res 26:340-6. 2002
    ..The present study was planned with the aim of investigating the effectiveness of metadoxine in the management of patients affected by acute ethanol intoxication...
  83. ncbi request reprint The GABA(B) receptor agonists baclofen and CGP 44532 prevent acquisition of alcohol drinking behaviour in alcohol-preferring rats
    Giancarlo Colombo
    C N R Institute of Neurogenetics and Neuropharmacology, Cagliari, Italy
    Alcohol Alcohol 37:499-503. 2002
    ..The present study investigated the effect of the gamma-aminobutyric acid (GABA)(B) receptor agonists, baclofen and CGP 44532, on the acquisition of alcohol drinking behaviour in selectively bred Sardinian alcohol-preferring (sP) rats...
  84. ncbi request reprint Safety and efficacy of GABAergic medications for treating alcoholism
    Bankole A Johnson
    Department of Psychiatric Medicine, The University of Virginia, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 29:248-54. 2005
    ..Johnson; (5) Evaluating the Risk of Benzodiazepine Prescription to Alcohol-Dependent Individuals, by Domenic A. Ciraulo; and (6) Safety and Efficacy of GABAergic Agents in Treating Alcoholics: Discussion, by Robert M. Swift...
  85. doi request reprint Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
    Arch Intern Med 168:1188-99. 2008
    ..We sought to determine whether topiramate's antidrinking effects are bolstered by improvements in physical and psychosocial well-being...
  86. ncbi request reprint Baclofen use in the treatment of alcohol delirium tremens
    Lorenzo Leggio
    Arch Intern Med 165:586; author reply 587. 2005
  87. ncbi request reprint Gamma-hydroxybutyrate as a treatment for alcoholism
    Fabio Caputo
    Lancet 366:981-2. 2005
  88. ncbi request reprint Gamma-hydroxybutyric acid
    Giovanni Addolorato
    N Engl J Med 353:1632-3. 2005
  89. ncbi request reprint Complementary medicine for alcohol dependence in Italian services: a mail questionnaire
    Gabriele Bardazzi
    Centro Diurno Alcologico, UFM C, Azienda Sanitaria Fiorentina, Villa Basilewsky, Via Lorenzo il Magnifico, 104, 50127 Firenze, Italy
    Complement Ther Clin Pract 12:216-21. 2006
    ..CM plays an integrated role with traditional forms of alcohol treatment in Italian alcohol services and this utilization could be useful to reduce drop-outs and improve alcohol treatment compliance...
  90. ncbi request reprint [The skin as a mirror of small intestine]
    Ludovico Abenavoli
    Istituto di Medicina Interna, Universita Cattolica del Sacro Cuore, Roma
    Recenti Prog Med 98:339-46. 2007
    ..The importance of these associations leads to conclude that skin is the "mirror" of the small intestine, and that remembering it can be necessary for specialist and generalist in their clinical practice...
  91. ncbi request reprint [Evaluation of liver fibrosis in clinical practice]
    Ludovico Abenavoli
    Istituto di Medicina Interna, Universita Cattolica del Sacro Cuore, Roma
    Recenti Prog Med 97:481-5. 2006
    ..Their improvement could lead to replacement of liver biopsy in the immediate future...
  92. ncbi request reprint Subclinical neurological abnormalities in patients with celiac disease: are they associated by brain hypoperfusion?
    Ludovico Abenavoli
    J Pediatr Gastroenterol Nutr 46:470. 2008
  93. doi request reprint An open randomized study of the treatment of escitalopram alone and combined with gamma-hydroxybutyric acid and naltrexone in alcoholic patients
    Luigi Stella
    Department of Experimental Medicine, Section of Pharmacology L Donatelli, Faculty of Medicine and Surgery, Second University of Naples, Naples, Italy
    Pharmacol Res 57:312-7. 2008
    ..Finally, in group 4 (NTX+GHB+SSRI), 1 patient relapsed after 3 months and 1 after 6 months, whereas 10 patients remain abstinent. In conclusion, the combination of NTX+GHB+SSRI was the most effective in preventing relapses...