Francesca Bruge

Summary

Country: Italy

Publications

  1. ncbi request reprint NAD(P)H:quinone oxidoreductase (NQO1) loss of function in Burkitt's lymphoma cell lines
    Francesca Bruge
    Institute of Biochemistry, Polytechnic University of the Marche, Ancona, Italy
    Biofactors 32:71-81. 2008
  2. doi request reprint Reference gene validation for qPCR on normoxia- and hypoxia-cultured human dermal fibroblasts exposed to UVA: is β-actin a reliable normalizer for photoaging studies?
    F Bruge
    Dipartimento Scienze Cliniche Specialistiche ed Odotontostomatologiche, Universita Politecnica delle Marche, I 60131 Ancona, Italy
    J Biotechnol 156:153-62. 2011
  3. doi request reprint Olive oil supplemented with menaquinone-7 significantly affects osteocalcin carboxylation
    Francesca Bruge
    Department of Biochemistry, Biology and Genetics, Polytechnic University of Marche, Via Ranieri, 60100 Ancona, Italy
    Br J Nutr 106:1058-62. 2011
  4. doi request reprint Nanostructured lipid carriers loaded with CoQ10: effect on human dermal fibroblasts under normal and UVA-mediated oxidative conditions
    Francesca Bruge
    Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Universita Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy
    Int J Pharm 455:348-56. 2013
  5. doi request reprint Olive oil supplemented with Coenzyme Q(10): effect on plasma and lipoprotein oxidative status
    Francesca Bruge
    Department of Clinical and Dental Sciences, Polytechnic University of Marche, Ancona, Italy
    Biofactors 38:249-56. 2012
  6. doi request reprint Anti-inflammatory effect of ubiquinol-10 on young and senescent endothelial cells via miR-146a modulation
    Fabiola Olivieri
    Department of Clinical and Molecular Sciences, Universita Politecnica delle Marche, 60020 Ancona, Italy
    Free Radic Biol Med 63:410-20. 2013
  7. doi request reprint Prolonged coenzyme Q10 treatment in Down syndrome patients: effect on DNA oxidation
    Luca Tiano
    Department of Biochemistry Biology and Genetics, Polytechnic University of Marche, Ancona, Italy
    Neurobiol Aging 33:626.e1-8. 2012
  8. pmc Prevention of UVA-induced oxidative damage in human dermal fibroblasts by new UV filters, assessed using a novel in vitro experimental system
    Francesca Bruge
    Dipartimento Scienze Cliniche Specialistiche ed Odontostomatologiche, Universita Politecnica delle Marche, Ancona, Italy
    PLoS ONE 9:e83401. 2014
  9. doi request reprint Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading
    Angelo Turi
    Department of Clinical Sciences, Unit of Obstetrics and Gynecology at G Salesi Hospital, Polytechnic University of Marche, Via F Corridoni 11, 60123 Ancona, Italy
    Arch Gynecol Obstet 285:1173-6. 2012
  10. doi request reprint Nitroxides and a nitroxide-based UV filter have the potential to photoprotect UVA-irradiated human skin fibroblasts against oxidative damage
    Elisabetta Venditti
    Dipartimento di Biochimica, Biologia e Genetica, Universita Politecnica delle Marche, I 60131 Ancona, Italy
    J Dermatol Sci 63:55-61. 2011

Collaborators

Detail Information

Publications11

  1. ncbi request reprint NAD(P)H:quinone oxidoreductase (NQO1) loss of function in Burkitt's lymphoma cell lines
    Francesca Bruge
    Institute of Biochemistry, Polytechnic University of the Marche, Ancona, Italy
    Biofactors 32:71-81. 2008
    ..On the other hand, this result suggests a careful re-evaluation of data concerning loss of NQO1 activity and polymorphisms in tumour cells...
  2. doi request reprint Reference gene validation for qPCR on normoxia- and hypoxia-cultured human dermal fibroblasts exposed to UVA: is β-actin a reliable normalizer for photoaging studies?
    F Bruge
    Dipartimento Scienze Cliniche Specialistiche ed Odotontostomatologiche, Universita Politecnica delle Marche, I 60131 Ancona, Italy
    J Biotechnol 156:153-62. 2011
    ..These reference genes are hence recommended for future qPCR analyses in studies concerning photo-damage on UVA-treated HDF...
  3. doi request reprint Olive oil supplemented with menaquinone-7 significantly affects osteocalcin carboxylation
    Francesca Bruge
    Department of Biochemistry, Biology and Genetics, Polytechnic University of Marche, Via Ranieri, 60100 Ancona, Italy
    Br J Nutr 106:1058-62. 2011
    ..We conclude that regular consumption of MK-7-enriched olive oil may constitute a valid approach in order to preserve some key biochemical mechanisms controlling bone mineralisation...
  4. doi request reprint Nanostructured lipid carriers loaded with CoQ10: effect on human dermal fibroblasts under normal and UVA-mediated oxidative conditions
    Francesca Bruge
    Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Universita Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy
    Int J Pharm 455:348-56. 2013
    ....
  5. doi request reprint Olive oil supplemented with Coenzyme Q(10): effect on plasma and lipoprotein oxidative status
    Francesca Bruge
    Department of Clinical and Dental Sciences, Polytechnic University of Marche, Ancona, Italy
    Biofactors 38:249-56. 2012
    ..These changes are associated with a decreased susceptibility of plasma lipoproteins to peroxidation associated with a chain-breaking antioxidant activity of the formulation...
  6. doi request reprint Anti-inflammatory effect of ubiquinol-10 on young and senescent endothelial cells via miR-146a modulation
    Fabiola Olivieri
    Department of Clinical and Molecular Sciences, Universita Politecnica delle Marche, 60020 Ancona, Italy
    Free Radic Biol Med 63:410-20. 2013
    ..These phenomena may play a role in preventing the endothelial dysfunction associated with major age-related diseases...
  7. doi request reprint Prolonged coenzyme Q10 treatment in Down syndrome patients: effect on DNA oxidation
    Luca Tiano
    Department of Biochemistry Biology and Genetics, Polytechnic University of Marche, Ancona, Italy
    Neurobiol Aging 33:626.e1-8. 2012
    ..Our results highlight an age-specific reduction in the percentage of cells showing the highest amount of oxidized bases, indicating a potential role of CoQ(10) in modulating DNA repair mechanisms...
  8. pmc Prevention of UVA-induced oxidative damage in human dermal fibroblasts by new UV filters, assessed using a novel in vitro experimental system
    Francesca Bruge
    Dipartimento Scienze Cliniche Specialistiche ed Odontostomatologiche, Universita Politecnica delle Marche, Ancona, Italy
    PLoS ONE 9:e83401. 2014
    ....
  9. doi request reprint Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading
    Angelo Turi
    Department of Clinical Sciences, Unit of Obstetrics and Gynecology at G Salesi Hospital, Polytechnic University of Marche, Via F Corridoni 11, 60123 Ancona, Italy
    Arch Gynecol Obstet 285:1173-6. 2012
    ..No data are available on the presence and content of Coenzyme Q10 (CoQ10) in human follicular fluid and its role...
  10. doi request reprint Nitroxides and a nitroxide-based UV filter have the potential to photoprotect UVA-irradiated human skin fibroblasts against oxidative damage
    Elisabetta Venditti
    Dipartimento di Biochimica, Biologia e Genetica, Universita Politecnica delle Marche, I 60131 Ancona, Italy
    J Dermatol Sci 63:55-61. 2011
    ....
  11. doi request reprint A novel Real Time PCR strategy to detect SOD3 SNP using LNA probes
    Francesca Bruge
    Department of Biochemistry, Biology and Genetics, Polytechnic University of Marche, Ancona, Italy
    Mutat Res 669:80-4. 2009
    ..Moreover, identification of patients with lowered vascular antioxidant defences could address pharmacogenomical approaches to the therapy of cardiovascular diseases...