Enzo Bonora

Summary

Country: Italy

Publications

  1. ncbi request reprint Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Italy
    Diabetes Care 23:57-63. 2000
  2. ncbi request reprint Predictors of insulin sensitivity in Type 2 diabetes mellitus
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Italy
    Diabet Med 19:535-42. 2002
  3. ncbi request reprint HOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the Verona Diabetes Complications Study
    Enzo Bonora
    Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes Care 25:1135-41. 2002
  4. ncbi request reprint Postprandial blood glucose as a risk factor for cardiovascular disease in Type II diabetes: the epidemiological evidence
    E Bonora
    Division of Endocrinology and Metabolic Disease, University of Verona Medical School, Ospedale Maggiore, Piazzale Stefani 1, Verona, Italy
    Diabetologia 44:2107-14. 2001
  5. ncbi request reprint Plasma glucose levels throughout the day and HbA(1c) interrelationships in type 2 diabetes: implications for treatment and monitoring of metabolic control
    E Bonora
    Division of Endocrinology and Metabolic Disease, University of Verona Medical School, Verona, Italy
    Diabetes Care 24:2023-9. 2001
  6. ncbi request reprint Intracellular partition of plasma glucose disposal in hypertensive and normotensive subjects with type 2 diabetes mellitus
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    J Clin Endocrinol Metab 86:2073-9. 2001
  7. ncbi request reprint Insulin resistance as estimated by homeostasis model assessment predicts incident symptomatic cardiovascular disease in caucasian subjects from the general population: the Bruneck study
    Enzo Bonora
    Endocrinologia e Malattie del Metabolismo, Ospedale Maggiore, Piazzale Stefani 1, 37126 Verona, Italy
    Diabetes Care 30:318-24. 2007
  8. doi request reprint Variability of body weight, pulse pressure and glycaemia strongly predict total mortality in elderly type 2 diabetic patients. The Verona Diabetes Study
    Giacomo Zoppini
    Division of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Diabetes Metab Res Rev 24:624-8. 2008
  9. ncbi request reprint Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes 53:1782-9. 2004
  10. doi request reprint Usefulness of the triglyceride to high-density lipoprotein cholesterol ratio for predicting mortality risk in type 2 diabetes: role of kidney dysfunction
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy
    Atherosclerosis 212:287-91. 2010

Detail Information

Publications45

  1. ncbi request reprint Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Italy
    Diabetes Care 23:57-63. 2000
    ..To evaluate whether the homeostasis model assessment (HOMA) is a reliable surrogate measure of in vivo insulin sensitivity in humans...
  2. ncbi request reprint Predictors of insulin sensitivity in Type 2 diabetes mellitus
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Italy
    Diabet Med 19:535-42. 2002
    ..To identify the independent predictors of insulin sensitivity in Type 2 diabetes, and to establish whether isolated Type 2 diabetes (i.e. diabetes without overweight, dyslipidaemia and hypertension) is a condition of insulin resistance...
  3. ncbi request reprint HOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the Verona Diabetes Complications Study
    Enzo Bonora
    Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes Care 25:1135-41. 2002
    ..To evaluate whether homeostasis model assessment-estimated insulin resistance (HOMA-IR) is an independent predictor of cardiovascular disease (CVD) in type 2 diabetes...
  4. ncbi request reprint Postprandial blood glucose as a risk factor for cardiovascular disease in Type II diabetes: the epidemiological evidence
    E Bonora
    Division of Endocrinology and Metabolic Disease, University of Verona Medical School, Ospedale Maggiore, Piazzale Stefani 1, Verona, Italy
    Diabetologia 44:2107-14. 2001
    ..Trials specifically designed to address this issue are needed to determine whether postprandial hyperglycaemia plays an independent and causative role in cardiovascular disease in patients with Type II diabetes...
  5. ncbi request reprint Plasma glucose levels throughout the day and HbA(1c) interrelationships in type 2 diabetes: implications for treatment and monitoring of metabolic control
    E Bonora
    Division of Endocrinology and Metabolic Disease, University of Verona Medical School, Verona, Italy
    Diabetes Care 24:2023-9. 2001
    ..To evaluate the extent of plasma glucose excursions with meals, the relations between plasma glucose levels at different times of the day, and the relations between the latter and HbA(1c) in non-insulin-treated type 2 diabetic subjects...
  6. ncbi request reprint Intracellular partition of plasma glucose disposal in hypertensive and normotensive subjects with type 2 diabetes mellitus
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    J Clin Endocrinol Metab 86:2073-9. 2001
    ..These results indicate that hypertension markedly aggravates insulin resistance featuring type 2 diabetes mellitus. The molecular defects underlying this phenomenon involve primarily GS...
  7. ncbi request reprint Insulin resistance as estimated by homeostasis model assessment predicts incident symptomatic cardiovascular disease in caucasian subjects from the general population: the Bruneck study
    Enzo Bonora
    Endocrinologia e Malattie del Metabolismo, Ospedale Maggiore, Piazzale Stefani 1, 37126 Verona, Italy
    Diabetes Care 30:318-24. 2007
    ....
  8. doi request reprint Variability of body weight, pulse pressure and glycaemia strongly predict total mortality in elderly type 2 diabetic patients. The Verona Diabetes Study
    Giacomo Zoppini
    Division of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Diabetes Metab Res Rev 24:624-8. 2008
    ....
  9. ncbi request reprint Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes 53:1782-9. 2004
    ....
  10. doi request reprint Usefulness of the triglyceride to high-density lipoprotein cholesterol ratio for predicting mortality risk in type 2 diabetes: role of kidney dysfunction
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy
    Atherosclerosis 212:287-91. 2010
    ....
  11. doi request reprint Non-alcoholic fatty liver disease is associated with an increased prevalence of atrial fibrillation in hospitalized patients with type 2 diabetes
    Giovanni Targher
    Section of Endocrinology, Diabetes and Metabolism, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
    Clin Sci (Lond) 125:301-9. 2013
    ..The potential impact of NAFLD on AF deserves particular attention, especially with respect to the implications for screening and surveillance strategies in the growing number of patients with NAFLD...
  12. ncbi request reprint Altered homeostatic adaptation of first- and second-phase beta-cell secretion in the offspring of patients with type 2 diabetes: studies with a minimal model to assess beta-cell function
    Riccardo C Bonadonna
    Division of Endocrinology and Metabolic Diseases, University of Verona and Azienda Ospedaliera di Verona, Italy
    Diabetes 52:470-80. 2003
    ..Under conditions leading to decreased insulin sensitivity, these disturbed relationships may lead to progression to diabetes in OfT2D...
  13. pmc CACNA1E variants affect beta cell function in patients with newly diagnosed type 2 diabetes. the Verona newly diagnosed type 2 diabetes study (VNDS) 3
    Maddalena Trombetta
    Department of Medicine, University of Verona, Verona, Italy
    PLoS ONE 7:e32755. 2012
    ..The aim of the study was to test whether CACNA1E common variability affects beta cell function and/or insulin sensitivity in patients with newly diagnosed type 2 diabetes...
  14. ncbi request reprint Pulse pressure and mortality from cerebrovascular diseases in type 2 diabetic patients: the Verona Diabetes Study
    Giacomo Zoppini
    Division of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Cerebrovasc Dis 23:20-6. 2007
    ..The aim of the present study was to investigate the relationship between PP and specific cardiovascular mortality, i.e. from cerebrovascular and ischemic heart diseases, in a well-characterized cohort of type 2 diabetic patients...
  15. pmc Serum uric acid levels and incident chronic kidney disease in patients with type 2 diabetes and preserved kidney function
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 35:99-104. 2012
    ..We determined whether baseline serum uric acid levels predict the subsequent development of CKD in patients with type 2 diabetes...
  16. doi request reprint Triglyceride-high-density lipoprotein cholesterol is associated with microvascular complications in type 2 diabetes mellitus
    Giacomo Zoppini
    Department of Medicine, Section of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Metabolism 61:22-9. 2012
    ....
  17. pmc Differences in the acute effects of aerobic and resistance exercise in subjects with type 2 diabetes: results from the RAED2 Randomized Trial
    Elisabetta Bacchi
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
    PLoS ONE 7:e49937. 2012
    ..Our objective was to assess whether there may be a difference in acute blood glucose changes after a single bout of AER or RES exercise...
  18. pmc Comparison of two creatinine-based estimating equations in predicting all-cause and cardiovascular mortality in patients with type 2 diabetes
    Giovanni Targher
    Section of Endocrinology and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
    Diabetes Care 35:2347-53. 2012
    ..To compare the performance of two glomerular filtration rate (GFR)-estimating equations in predicting the risk of all-cause and cardiovascular mortality in type 2 diabetic patients...
  19. doi request reprint Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes
    Giovanni Targher
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    J Hepatol 53:713-8. 2010
    ..To estimate the prevalence of non-alcoholic fatty liver disease (NAFLD) in type 1 diabetic individuals, and to evaluate whether NAFLD is associated with increased prevalence of cardiovascular disease (CVD)...
  20. pmc Metabolic effects of aerobic training and resistance training in type 2 diabetic subjects: a randomized controlled trial (the RAED2 study)
    Elisabetta Bacchi
    Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 35:676-82. 2012
    ....
  21. doi request reprint Predictors of estimated GFR decline in patients with type 2 diabetes and preserved kidney function
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Italy
    Clin J Am Soc Nephrol 7:401-8. 2012
    ..This study examined predictors of the annual decline in estimated GFR (eGFR) in patients with type 2 diabetes and preserved kidney function...
  22. ncbi request reprint Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database
    Enzo Bonora
    University of Verona, Verona, Italy
    Nutr Metab Cardiovasc Dis 18:624-31. 2008
    ..We evaluated whether hyperinsulinemia and/or insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects...
  23. pmc Elevated serum uric acid concentrations independently predict cardiovascular mortality in type 2 diabetic patients
    Giacomo Zoppini
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Diabetes Care 32:1716-20. 2009
    ..We assessed the predictive role of serum uric acid levels on all-cause and cardiovascular mortality in a large cohort of type 2 diabetic individuals...
  24. doi request reprint Increased risk of cardiovascular disease and chronic kidney disease in NAFLD
    Enzo Bonora
    Endocrinology, Diabetes and Metabolic Diseases, University and Azienda Ospedaliera Universitaria Integrata of Verona, Ospedale Civile Maggiore, Piazzale Stefani 1, 37126 Verona, Italy
    Nat Rev Gastroenterol Hepatol 9:372-81. 2012
    ....
  25. pmc Aortic and mitral annular calcifications are predictive of all-cause and cardiovascular mortality in patients with type 2 diabetes
    Andrea Rossi
    Section of Cardiology, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
    Diabetes Care 35:1781-6. 2012
    ..To examine the association of aortic valve sclerosis (AVS) and mitral annulus calcification (MAC) with all-cause and cardiovascular mortality in type 2 diabetic individuals...
  26. pmc Supervised walking groups to increase physical activity in type 2 diabetic patients
    Carlo Negri
    Unit of Endocrinology and Metabolism, Azienda Ospedaliera Universitaria Integrata di Verona, Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 33:2333-5. 2010
    ..To evaluate the impact of an exercise program organized into supervised walking groups in subjects with type 2 diabetes...
  27. doi request reprint Risk of chronic kidney disease in patients with non-alcoholic fatty liver disease: is there a link?
    Giovanni Targher
    Section of Endocrinology and Metabolism, Department of Medicine, University Hospital, Verona, Italy
    J Hepatol 54:1020-9. 2011
    ....
  28. pmc High-normal HbA1c is a strong predictor of type 2 diabetes in the general population
    Enzo Bonora
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 34:1038-40. 2011
    ..In this study we evaluated how high-normal HbA(1c) levels predict type 2 diabetes...
  29. ncbi request reprint Carotid atherosclerosis and coronary heart disease in the metabolic syndrome: prospective data from the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes Care 26:1251-7. 2003
    ..The present study aimed at prospectively evaluating carotid atherosclerosis and coronary heart disease (CHD) in subjects with the metabolic syndrome...
  30. ncbi request reprint Protection of pancreatic beta-cells: is it feasible?
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Nutr Metab Cardiovasc Dis 18:74-83. 2008
    ..Anti-diabetic agents targeting the intimate mechanisms of beta-cell damage might change the scenario in the near future...
  31. ncbi request reprint The metabolic syndrome and cardiovascular disease
    Enzo Bonora
    Department of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Ann Med 38:64-80. 2006
    ..The risk related to the metabolic syndrome is definitely higher when subjects affected are compared to subjects free of any metabolic abnormality...
  32. ncbi request reprint Mortality from site-specific malignancies in type 2 diabetic patients from Verona
    Giuseppe Verlato
    Unit of Epidemiology and Medical Statistics, University of Verona, Verona, Italy
    Diabetes Care 26:1047-51. 2003
    ..The aim of the present work was to compare mortality from site-specific malignancies in type 2 diabetic patients with those in the general population...
  33. pmc Variants of GCKR affect both β-cell and kidney function in patients with newly diagnosed type 2 diabetes: the Verona newly diagnosed type 2 diabetes study 2
    Sara Bonetti
    Department ofMedicine, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
    Diabetes Care 34:1205-10. 2011
    ..We tested whether GCKR variability affects type 2 diabetes or kidney-related phenotypes in newly diagnosed type 2 diabetes...
  34. ncbi request reprint Insulin causes endothelial dysfunction in humans: sites and mechanisms
    Guido Arcaro
    Division of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona Medical School and Azienda Ospedaliera di Verona, Verona, Italy
    Circulation 105:576-82. 2002
    ..Endothelium plays a central role in atherogenesis. The in vivo effects of hyperinsulinemia on endothelial function of large conduit arteries are unknown...
  35. doi request reprint Hemostatic and fibrinolytic abnormalities in endocrine diseases: a narrative review
    Giovanni Targher
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Semin Thromb Hemost 35:605-12. 2009
    ..Nevertheless, the prompt recognition of potentially severe disorders of blood coagulation is mandatory for the correct management of these patients...
  36. ncbi request reprint European guidelines on cardiovascular disease prevention in clinical practice: executive summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (Constituted by r
    Ian Graham
    Department of Cardiology, Adelaide and Meath Hospital, Dublin, Ireland
    Eur Heart J 28:2375-414. 2007
  37. ncbi request reprint European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by r
    Ian Graham
    Department of Cardiology, The Adelaide and Meath Hospital, Tallaght, Doublin, Ireland
    Eur J Cardiovasc Prev Rehabil 14:E1-40. 2007
  38. ncbi request reprint European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by represent
    Ian Graham
    Department of Cardiology, The Adelaide and Meath Hospital, Tallaght, Dublin, Ireland
    Eur J Cardiovasc Prev Rehabil 14:S1-113. 2007
  39. ncbi request reprint Impact of lowering the criterion for impaired fasting glucose on identification of individuals with insulin resistance. The GISIR database
    Giorgio Sesti
    Department of Experimental and Clinical Medicine, University of Catanzaro, Italy
    Diabetes Metab Res Rev 24:130-6. 2008
    ..We assessed the accuracy of the American Diabetes Association (ADA)2003 definition of impaired fasting glucose (IFG) in identifying subjects with low insulin sensitivity, and determined cardiovascular risk factors in ADA2003 IFG subjects...
  40. ncbi request reprint [European practice guidelines on prevention of cardiovascular diseases: executive summary]
    Ian Graham
    European Society of Cardiology
    G Ital Cardiol (Rome) 9:11-59. 2008
  41. ncbi request reprint [Abdominal obesity and diabetes]
    Enzo Bonora
    Sezione di Endocrinologia e Malattie del Metabolismo, Dipartimento di Scienze Biomediche e Chirurgiche, Universita degli Studi, Verona
    G Ital Cardiol (Rome) 9:40S-53S. 2008
    ..ceramide) within the key organs of glucose metabolism (liver, skeletal muscle, pancreatic islets). This phenomenon seems to contribute to both insulin resistance and beta-cell dysfunction, favoring abnormalities of glucose homeostasis...
  42. ncbi request reprint Insulin effect on serum potassium and auto-inhibition of insulin secretion is intact in a patient with leprechaunism despite severe impairment of substrates metabolism
    Livio Luzi
    Department of Medicine, San Raffaele Scientific Institute, and University of Milano, Milano, Italy
    Diabetes Metab Res Rev 24:205-10. 2008
    ..The mutations do not affect the insulin-receptor binding affinity and insulin-stimulated auto-phosphorylation of the receptor...
  43. ncbi request reprint Serum leptin level and the risk of nontraumatic fracture
    Georg Schett
    Division of Rheumatology, Department of Internal Medicine III, University of Vienna, Austria
    Am J Med 117:952-6. 2004
  44. ncbi request reprint Correspondence between the International Diabetes Federation criteria for metabolic syndrome and insulin resistance in a cohort of Italian nondiabetic Caucasians: the GISIR database
    Giorgio Sesti
    Diabetes Care 30:e33. 2007
  45. ncbi request reprint Imatinib and regression of type 2 diabetes
    Dino Veneri
    N Engl J Med 352:1049-50. 2005