Enzo Bonora

Summary

Country: Italy

Publications

  1. ncbi Carotid atherosclerosis and coronary heart disease in the metabolic syndrome: prospective data from the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes Care 26:1251-7. 2003
  2. ncbi Insulin resistance as estimated by homeostasis model assessment predicts incident symptomatic cardiovascular disease in caucasian subjects from the general population: the Bruneck study
    Enzo Bonora
    Endocrinologia e Malattie del Metabolismo, Ospedale Maggiore, Piazzale Stefani 1, 37126 Verona, Italy
    Diabetes Care 30:318-24. 2007
  3. ncbi Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University Hospital, Piazzale Stefani, 1, 37126, Verona, Italy
    Diabetologia 49:846-54. 2006
  4. ncbi The metabolic syndrome and cardiovascular disease
    Enzo Bonora
    Department of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Ann Med 38:64-80. 2006
  5. ncbi Protection of pancreatic beta-cells: is it feasible?
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Nutr Metab Cardiovasc Dis 18:74-83. 2008
  6. ncbi Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes 53:1782-9. 2004
  7. ncbi The Metabolic Syndrome is an independent predictor of cardiovascular disease in Type 2 diabetic subjects. Prospective data from the Verona Diabetes Complications Study
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabet Med 21:52-8. 2004
  8. ncbi Metabolic syndrome: epidemiology and more extensive phenotypic description. Cross-sectional data from the Bruneck Study
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Int J Obes Relat Metab Disord 27:1283-9. 2003
  9. ncbi Predictors of estimated GFR decline in patients with type 2 diabetes and preserved kidney function
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Italy
    Clin J Am Soc Nephrol 7:401-8. 2012
  10. ncbi Variability of body weight, pulse pressure and glycaemia strongly predict total mortality in elderly type 2 diabetic patients. The Verona Diabetes Study
    Giacomo Zoppini
    Division of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Diabetes Metab Res Rev 24:624-8. 2008

Detail Information

Publications47

  1. ncbi Carotid atherosclerosis and coronary heart disease in the metabolic syndrome: prospective data from the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes Care 26:1251-7. 2003
    ..The present study aimed at prospectively evaluating carotid atherosclerosis and coronary heart disease (CHD) in subjects with the metabolic syndrome...
  2. ncbi Insulin resistance as estimated by homeostasis model assessment predicts incident symptomatic cardiovascular disease in caucasian subjects from the general population: the Bruneck study
    Enzo Bonora
    Endocrinologia e Malattie del Metabolismo, Ospedale Maggiore, Piazzale Stefani 1, 37126 Verona, Italy
    Diabetes Care 30:318-24. 2007
    ....
  3. ncbi Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University Hospital, Piazzale Stefani, 1, 37126, Verona, Italy
    Diabetologia 49:846-54. 2006
    ....
  4. ncbi The metabolic syndrome and cardiovascular disease
    Enzo Bonora
    Department of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Ann Med 38:64-80. 2006
    ..The risk related to the metabolic syndrome is definitely higher when subjects affected are compared to subjects free of any metabolic abnormality...
  5. ncbi Protection of pancreatic beta-cells: is it feasible?
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Nutr Metab Cardiovasc Dis 18:74-83. 2008
    ..Anti-diabetic agents targeting the intimate mechanisms of beta-cell damage might change the scenario in the near future...
  6. ncbi Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes 53:1782-9. 2004
    ....
  7. ncbi The Metabolic Syndrome is an independent predictor of cardiovascular disease in Type 2 diabetic subjects. Prospective data from the Verona Diabetes Complications Study
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabet Med 21:52-8. 2004
    ..To evaluate the cardiovascular risk associated with the presence of the Metabolic Syndrome in Type 2 diabetic subjects...
  8. ncbi Metabolic syndrome: epidemiology and more extensive phenotypic description. Cross-sectional data from the Bruneck Study
    E Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Int J Obes Relat Metab Disord 27:1283-9. 2003
    ..The present study aimed at evaluating the prevalence of the Metabolic Syndrome and at identifying its additional clinical features...
  9. ncbi Predictors of estimated GFR decline in patients with type 2 diabetes and preserved kidney function
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Italy
    Clin J Am Soc Nephrol 7:401-8. 2012
    ..This study examined predictors of the annual decline in estimated GFR (eGFR) in patients with type 2 diabetes and preserved kidney function...
  10. ncbi Variability of body weight, pulse pressure and glycaemia strongly predict total mortality in elderly type 2 diabetic patients. The Verona Diabetes Study
    Giacomo Zoppini
    Division of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Diabetes Metab Res Rev 24:624-8. 2008
    ....
  11. ncbi Usefulness of the triglyceride to high-density lipoprotein cholesterol ratio for predicting mortality risk in type 2 diabetes: role of kidney dysfunction
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy
    Atherosclerosis 212:287-91. 2010
    ....
  12. ncbi Anaemia, independent of chronic kidney disease, predicts all-cause and cardiovascular mortality in type 2 diabetic patients
    Giacomo Zoppini
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Ospedale Civile Maggiore, Piazzale Stefani, 1, 37126 Verona, Italy
    Atherosclerosis 210:575-80. 2010
    ..We assessed the predictive role of lower hemoglobin concentrations on all-cause and cardiovascular mortality in a cohort of type 2 diabetic individuals...
  13. ncbi CACNA1E variants affect beta cell function in patients with newly diagnosed type 2 diabetes. the Verona newly diagnosed type 2 diabetes study (VNDS) 3
    Maddalena Trombetta
    Department of Medicine, University of Verona, Verona, Italy
    PLoS ONE 7:e32755. 2012
    ..The aim of the study was to test whether CACNA1E common variability affects beta cell function and/or insulin sensitivity in patients with newly diagnosed type 2 diabetes...
  14. ncbi Impact of reference category and number of traits in the cluster on risk of coronary heart disease in metabolic syndrome: prospective data from the Bruneck study
    Enzo Bonora
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona, Italy
    Metab Syndr Relat Disord 9:313-8. 2011
    ..We assessed the risk of coronary heart disease (CHD) in subjects with metabolic syndrome using different reference categories and focusing on the number of traits in the cluster...
  15. ncbi Altered homeostatic adaptation of first- and second-phase beta-cell secretion in the offspring of patients with type 2 diabetes: studies with a minimal model to assess beta-cell function
    Riccardo C Bonadonna
    Division of Endocrinology and Metabolic Diseases, University of Verona and Azienda Ospedaliera di Verona, Italy
    Diabetes 52:470-80. 2003
    ..Under conditions leading to decreased insulin sensitivity, these disturbed relationships may lead to progression to diabetes in OfT2D...
  16. ncbi HOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the Verona Diabetes Complications Study
    Enzo Bonora
    Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes Care 25:1135-41. 2002
    ..To evaluate whether homeostasis model assessment-estimated insulin resistance (HOMA-IR) is an independent predictor of cardiovascular disease (CVD) in type 2 diabetes...
  17. ncbi Pulse pressure and mortality from cerebrovascular diseases in type 2 diabetic patients: the Verona Diabetes Study
    Giacomo Zoppini
    Division of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Cerebrovasc Dis 23:20-6. 2007
    ..The aim of the present study was to investigate the relationship between PP and specific cardiovascular mortality, i.e. from cerebrovascular and ischemic heart diseases, in a well-characterized cohort of type 2 diabetic patients...
  18. ncbi Serum uric acid levels and incident chronic kidney disease in patients with type 2 diabetes and preserved kidney function
    Giacomo Zoppini
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 35:99-104. 2012
    ..We determined whether baseline serum uric acid levels predict the subsequent development of CKD in patients with type 2 diabetes...
  19. ncbi Triglyceride-high-density lipoprotein cholesterol is associated with microvascular complications in type 2 diabetes mellitus
    Giacomo Zoppini
    Department of Medicine, Section of Endocrinology and Metabolic Diseases, University of Verona, Verona, Italy
    Metabolism 61:22-9. 2012
    ....
  20. ncbi Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes
    Giovanni Targher
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    J Hepatol 53:713-8. 2010
    ..To estimate the prevalence of non-alcoholic fatty liver disease (NAFLD) in type 1 diabetic individuals, and to evaluate whether NAFLD is associated with increased prevalence of cardiovascular disease (CVD)...
  21. ncbi Metabolic effects of aerobic training and resistance training in type 2 diabetic subjects: a randomized controlled trial (the RAED2 study)
    Elisabetta Bacchi
    Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 35:676-82. 2012
    ....
  22. ncbi Elevated serum uric acid concentrations independently predict cardiovascular mortality in type 2 diabetic patients
    Giacomo Zoppini
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Diabetes Care 32:1716-20. 2009
    ..We assessed the predictive role of serum uric acid levels on all-cause and cardiovascular mortality in a large cohort of type 2 diabetic individuals...
  23. ncbi Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database
    Enzo Bonora
    University of Verona, Verona, Italy
    Nutr Metab Cardiovasc Dis 18:624-31. 2008
    ..We evaluated whether hyperinsulinemia and/or insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects...
  24. ncbi Increased risk of cardiovascular disease and chronic kidney disease in NAFLD
    Enzo Bonora
    Endocrinology, Diabetes and Metabolic Diseases, University and Azienda Ospedaliera Universitaria Integrata of Verona, Ospedale Civile Maggiore, Piazzale Stefani 1, 37126 Verona, Italy
    Nat Rev Gastroenterol Hepatol 9:372-81. 2012
    ....
  25. ncbi Aortic and mitral annular calcifications are predictive of all-cause and cardiovascular mortality in patients with type 2 diabetes
    Andrea Rossi
    Section of Cardiology, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
    Diabetes Care 35:1781-6. 2012
    ..To examine the association of aortic valve sclerosis (AVS) and mitral annulus calcification (MAC) with all-cause and cardiovascular mortality in type 2 diabetic individuals...
  26. ncbi Differences in the acute effects of aerobic and resistance exercise in subjects with type 2 diabetes: results from the RAED2 Randomized Trial
    Elisabetta Bacchi
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
    PLoS ONE 7:e49937. 2012
    ..Our objective was to assess whether there may be a difference in acute blood glucose changes after a single bout of AER or RES exercise...
  27. ncbi Hyperinsulinemia amplifies GnRH agonist stimulated ovarian steroid secretion in women with polycystic ovary syndrome
    Flavia Tosi
    Division of Endocrinology and Metabolism, University and Azienda Ospedaliera Universitaria Integrata Verona, I 37126 Verona, Italy
    J Clin Endocrinol Metab 97:1712-9. 2012
    ..In vitro data show that insulin may enhance basal and LH-stimulated ovarian androgen secretion, particularly in theca cells from women with polycystic ovary syndrome (PCOS). However, in vivo studies gave inconsistent results...
  28. ncbi Risk of chronic kidney disease in patients with non-alcoholic fatty liver disease: is there a link?
    Giovanni Targher
    Section of Endocrinology and Metabolism, Department of Medicine, University Hospital, Verona, Italy
    J Hepatol 54:1020-9. 2011
    ....
  29. ncbi High-normal HbA1c is a strong predictor of type 2 diabetes in the general population
    Enzo Bonora
    Section of Endocrinology and Metabolism, Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 34:1038-40. 2011
    ..In this study we evaluated how high-normal HbA(1c) levels predict type 2 diabetes...
  30. ncbi Supervised walking groups to increase physical activity in type 2 diabetic patients
    Carlo Negri
    Unit of Endocrinology and Metabolism, Azienda Ospedaliera Universitaria Integrata di Verona, Department of Medicine, University of Verona, Verona, Italy
    Diabetes Care 33:2333-5. 2010
    ..To evaluate the impact of an exercise program organized into supervised walking groups in subjects with type 2 diabetes...
  31. ncbi Insulin enhances ACTH-stimulated androgen and glucocorticoid metabolism in hyperandrogenic women
    Flavia Tosi
    Division of Endocrinology and Metabolism Clinical Chemistry Laboratory, University and Azienda Integrata Ospedaliera Universitaria di Verona, P le Stefani 1, 37126 Verona, Italy
    Eur J Endocrinol 164:197-203. 2011
    ..The aim of the study is to assess whether acute hyperinsulinaemia determines absolute changes in either basal or ACTH-stimulated adrenal steroidogenesis in these subjects...
  32. ncbi Mortality from site-specific malignancies in type 2 diabetic patients from Verona
    Giuseppe Verlato
    Unit of Epidemiology and Medical Statistics, University of Verona, Verona, Italy
    Diabetes Care 26:1047-51. 2003
    ..CONCLUSIONS: Mortality from site-specific malignancies is different in type 2 diabetic patients than in the general population. Better control of body weight seems necessary to prevent the excess mortality from breast cancer in women...
  33. ncbi Insulin causes endothelial dysfunction in humans: sites and mechanisms
    Guido Arcaro
    Division of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona Medical School and Azienda Ospedaliera di Verona, Verona, Italy
    Circulation 105:576-82. 2002
    ..These data may provide a novel pathophysiological basis to the epidemiological link between hyperinsulinemia/insulin-resistance and atherosclerosis in humans...
  34. ncbi Hemostatic and fibrinolytic abnormalities in endocrine diseases: a narrative review
    Giovanni Targher
    Section of Endocrinology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
    Semin Thromb Hemost 35:605-12. 2009
    ..Nevertheless, the prompt recognition of potentially severe disorders of blood coagulation is mandatory for the correct management of these patients...
  35. ncbi Variants of GCKR affect both β-cell and kidney function in patients with newly diagnosed type 2 diabetes: the Verona newly diagnosed type 2 diabetes study 2
    Sara Bonetti
    Department ofMedicine, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
    Diabetes Care 34:1205-10. 2011
    ..We tested whether GCKR variability affects type 2 diabetes or kidney-related phenotypes in newly diagnosed type 2 diabetes...
  36. ncbi Divergences in insulin resistance between the different phenotypes of the polycystic ovary syndrome
    Paolo Moghetti
    Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona, Piazzale Stefani, 1 I 37126 Verona, Italy
    J Clin Endocrinol Metab 98:E628-37. 2013
    ..In metabolic terms, women belonging to the normoandrogenic phenotype behave as a separate group...
  37. ncbi Correspondence between the International Diabetes Federation criteria for metabolic syndrome and insulin resistance in a cohort of Italian nondiabetic Caucasians: the GISIR database
    Giorgio Sesti
    Diabetes Care 30:e33. 2007
  38. ncbi [European practice guidelines on prevention of cardiovascular diseases: executive summary]
    Ian Graham
    European Society of Cardiology
    G Ital Cardiol (Rome) 9:11-59. 2008
  39. ncbi European guidelines on cardiovascular disease prevention in clinical practice: executive summary
    Ian Graham
    Department of Cardiology, The Adelaide and Meath Hospital, Dublin, Ireland
    Eur Heart J 28:2375-414. 2007
  40. ncbi European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by r
    Ian Graham
    Department of Cardiology, The Adelaide and Meath Hospital, Tallaght, Doublin, Ireland
    Eur J Cardiovasc Prev Rehabil 14:E1-40. 2007
  41. ncbi Impact of lowering the criterion for impaired fasting glucose on identification of individuals with insulin resistance. The GISIR database
    Giorgio Sesti
    Department of Experimental and Clinical Medicine, University of Catanzaro, Italy
    Diabetes Metab Res Rev 24:130-6. 2008
    ..We assessed the accuracy of the American Diabetes Association (ADA)2003 definition of impaired fasting glucose (IFG) in identifying subjects with low insulin sensitivity, and determined cardiovascular risk factors in ADA2003 IFG subjects...
  42. ncbi [Abdominal obesity and diabetes]
    Enzo Bonora
    Sezione di Endocrinologia e Malattie del Metabolismo, Dipartimento di Scienze Biomediche e Chirurgiche, Universita degli Studi, Verona
    G Ital Cardiol (Rome) 9:40S-53S. 2008
    ..ceramide) within the key organs of glucose metabolism (liver, skeletal muscle, pancreatic islets). This phenomenon seems to contribute to both insulin resistance and beta-cell dysfunction, favoring abnormalities of glucose homeostasis...
  43. ncbi European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by represent
    Ian Graham
    Department of Cardiology, The Adelaide and Meath Hospital, Tallaght, Dublin, Ireland
    Eur J Cardiovasc Prev Rehabil 14:S1-113. 2007
  44. ncbi Insulin effect on serum potassium and auto-inhibition of insulin secretion is intact in a patient with leprechaunism despite severe impairment of substrates metabolism
    Livio Luzi
    Department of Medicine, San Raffaele Scientific Institute, and University of Milano, Milano, Italy
    Diabetes Metab Res Rev 24:205-10. 2008
    ..The mutations do not affect the insulin-receptor binding affinity and insulin-stimulated auto-phosphorylation of the receptor...
  45. ncbi Imatinib and regression of type 2 diabetes
    Dino Veneri
    N Engl J Med 352:1049-50. 2005
  46. ncbi Serum leptin level and the risk of nontraumatic fracture
    Georg Schett
    Division of Rheumatology, Department of Internal Medicine III, University of Vienna, Austria
    Am J Med 117:952-6. 2004
  47. ncbi Toll-like receptor 4 polymorphisms and atherogenesis
    Stefan Kiechl
    Department of Neurology, University Clinic, Innsbruck, Austria
    N Engl J Med 347:185-92. 2002
    ..We determined whether recently discovered genetic variants of toll-like receptor 4 (TLR4) that confer differences in the inflammatory response elicited by bacterial lipopolysaccharide are related to the development of atherosclerosis...