Giuseppina Bonizzi

Summary

Country: Italy

Publications

  1. ncbi request reprint The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    Giuseppina Bonizzi
    Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0636, USA
    Trends Immunol 25:280-8. 2004
  2. pmc Regulation of late B cell differentiation by intrinsic IKKalpha-dependent signals
    David M Mills
    Burnham Institute for Medical Research, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 104:6359-64. 2007
  3. ncbi request reprint Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease
    Thomas Enzler
    Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA
    Immunity 25:403-15. 2006
  4. pmc Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers
    Giuseppina Bonizzi
    Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0636, USA
    EMBO J 23:4202-10. 2004
  5. ncbi request reprint I kappa B kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue
    Danielle L Drayton
    Department of Epidemiology and Public Health, Section of Immunobiology, Yale University School of Medicine, 60 College Street, New Haven, CT 06520, USA
    J Immunol 173:6161-8. 2004

Collaborators

  • Michael Karin
  • Gourisankar Ghosh
  • David M Mills
  • Robert C Rickert
  • Thomas Enzler
  • Danielle L Drayton
  • Dennis C Otero
  • George F Widhopf
  • Amy Anzelon-Mills
  • Gregg J Silverman
  • Nancy H Ruddle
  • Xiaoyan Ying
  • Shan Liao

Detail Information

Publications5

  1. ncbi request reprint The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    Giuseppina Bonizzi
    Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0636, USA
    Trends Immunol 25:280-8. 2004
  2. pmc Regulation of late B cell differentiation by intrinsic IKKalpha-dependent signals
    David M Mills
    Burnham Institute for Medical Research, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 104:6359-64. 2007
    ..Thus, the NIK-IKKalpha-p52 axis is not as linear and exclusive as previous studies suggest, and IKKalpha possesses critical NF-kappaB-independent functions in B cells...
  3. ncbi request reprint Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease
    Thomas Enzler
    Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA
    Immunity 25:403-15. 2006
    ..Thus, both classical and alternative NF-kappaB signaling are important for development of lupus-like disease associated with BAFF overproduction. The same mechanisms may be involved in the pathogenesis of human SLE...
  4. pmc Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers
    Giuseppina Bonizzi
    Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0636, USA
    EMBO J 23:4202-10. 2004
    ..This site links induction of organogenic chemokines and other important regulatory molecules to activation of the alternative pathway...
  5. ncbi request reprint I kappa B kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue
    Danielle L Drayton
    Department of Epidemiology and Public Health, Section of Immunobiology, Yale University School of Medicine, 60 College Street, New Haven, CT 06520, USA
    J Immunol 173:6161-8. 2004
    ....