Franco Benazzi

Summary

Country: Italy

Publications

  1. ncbi Challenging the unipolar-bipolar division: does mixed depression bridge the gap?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 31:97-103. 2007
  2. ncbi How best to identify a bipolar-related subtype among major depressive patients without spontaneous hypomania: superiority of age at onset criterion over recurrence and polarity?
    Franco Benazzi
    Hecker Psychiatry Research Center, Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 107:77-88. 2008
  3. doi Defining mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:932-9. 2008
  4. ncbi Challenging DSM-IV criteria for hypomania: diagnosing based on number of no-priority symptoms
    Franco Benazzi
    Hecker Psychiatry Research Center at Forli, Forli, Italy
    Eur Psychiatry 22:99-103. 2007
  5. ncbi Psychometric delineation of the most discriminant symptoms of depressive mixed states
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Psychiatry Res 141:81-8. 2006
  6. ncbi A tetrachoric factor analysis validation of mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:186-92. 2008
  7. ncbi Testing new diagnostic criteria for hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Ann Clin Psychiatry 19:99-104. 2007
  8. ncbi The continuum/spectrum concept of mood disorders: is mixed depression the basic link?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Arch Psychiatry Clin Neurosci 256:512-5. 2006
  9. ncbi Irritable-hostile depression: further validation as a bipolar depressive mixed state
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:197-207. 2005
  10. ncbi A downscaled practical measure of mood lability as a screening tool for bipolar II
    Franco Benazzi
    Outpatient Psychiatry Center Ravenna and Forli, Italy and the Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:225-32. 2005

Detail Information

Publications76

  1. ncbi Challenging the unipolar-bipolar division: does mixed depression bridge the gap?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 31:97-103. 2007
    ..A correlation between intradepressive hypomanic symptoms and depressive symptoms could support such a continuum, but other explanations of a correlation are possible...
  2. ncbi How best to identify a bipolar-related subtype among major depressive patients without spontaneous hypomania: superiority of age at onset criterion over recurrence and polarity?
    Franco Benazzi
    Hecker Psychiatry Research Center, Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 107:77-88. 2008
    ..History of high depressive recurrence (without history of mania/hypomania) has been proposed as a mood subtype close to bipolar disorders. Herein we test whether this is the best approach to this question...
  3. doi Defining mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:932-9. 2008
    ..However, it is still unclear if its definition should be based on specific manic symptoms or on a number/score of manic symptoms. Different definitions may have different diagnostic utility, such as treatment impacts...
  4. ncbi Challenging DSM-IV criteria for hypomania: diagnosing based on number of no-priority symptoms
    Franco Benazzi
    Hecker Psychiatry Research Center at Forli, Forli, Italy
    Eur Psychiatry 22:99-103. 2007
    ..DSM-IV definition of hypomania of bipolar-II disorder (BP-II), which includes elevated/irritable mood change as core feature (i.e., it must always be present), is not based on sound evidence...
  5. ncbi Psychometric delineation of the most discriminant symptoms of depressive mixed states
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Psychiatry Res 141:81-8. 2006
    ..Beyond its diagnostic significance, the foregoing signs and symptoms are among the clinical features the FDA lists as presaging "suicidality" on antidepressant monotherapy...
  6. ncbi A tetrachoric factor analysis validation of mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 32:186-92. 2008
    ..However, its diagnostic validity and bipolar nature are still not firmly supported. A bipolar nature could have significant treatment impacts...
  7. ncbi Testing new diagnostic criteria for hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Ann Clin Psychiatry 19:99-104. 2007
    ..Angst has suggested new criteria for hypomania, giving priority to overactivity. Study aim was to test the validity of Angst's diagnostic criteria for hypomania...
  8. ncbi The continuum/spectrum concept of mood disorders: is mixed depression the basic link?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Eur Arch Psychiatry Clin Neurosci 256:512-5. 2006
    ..No bi-modality, and a dose-response relationship, would not support a categorical distinction...
  9. ncbi Irritable-hostile depression: further validation as a bipolar depressive mixed state
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:197-207. 2005
    ..A veritable tower of Babel indeed. In the present analyses, our aim was to extend previous research on irritable-hostile depression to more specific parameters of bipolarity and depressive mixed state (DMX)...
  10. ncbi A downscaled practical measure of mood lability as a screening tool for bipolar II
    Franco Benazzi
    Outpatient Psychiatry Center Ravenna and Forli, Italy and the Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 84:225-32. 2005
    ..Accordingly, the aim of the present analyses was to test if a practical measure of mood lability was unique to BPII, in comparison with major depressive disorder (MDD)...
  11. ncbi Symptoms of depression as possible markers of bipolar II disorder
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:471-7. 2006
    ..The study aim was to find which symptoms of depression could be possible cross-sectional markers of BP-II, in order to reduce underdiagnosing BP-II...
  12. doi Classifying mood disorders by age-at-onset instead of polarity
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 33:86-93. 2009
    ..A reshaping of the classification of mood disorders thus seems required. Age-at-onset and recurrence have been suggested to be more clinically and genetically useful in the phenotyping of mood disorders...
  13. ncbi Impact of temperamental mood lability on depressive mixed state
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Psychopathology 39:19-24. 2006
    ..The study aim was to find the impact of temperamental mood lability (TML) on DMX...
  14. ncbi Depressive mixed state: dimensional versus categorical definitions
    Franco Benazzi
    Outpatient Psychiatry Center, Via Pozzetto 17, 48015 Castiglione di Cervia RA, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 27:129-34. 2003
    ..It is still unclear how to best define DMX. The study's aim was to test a categorical versus a dimensional definition of DMX...
  15. ncbi Does age at onset support a dimensional relationship between Bipolar II disorder and major depressive disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    World J Biol Psychiatry 8:105-11. 2007
    ..The bi-modality and dose-response approaches, versus classic diagnostic validators, seem to support a dimensional relationship between BP-II and MDD...
  16. ncbi Testing predictors of bipolar-II disorder with a 2-day minimum duration of hypomania
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Psychiatry Res 153:153-62. 2007
    ..As PPV is related to disease prevalence, findings need to be replicated in different settings...
  17. ncbi Bipolar disorder--focus on bipolar II disorder and mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Lancet 369:935-45. 2007
    ..Controlled studies are needed to investigate treatment of mixed depression; antidepressants can worsen manic and hypomanic symptoms, and mood stabilising agents might be necessary...
  18. ncbi Bipolar family history of the hypomanic symptoms and dimensions of mixed depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Ravenna, Italy
    Compr Psychiatry 46:399-404. 2005
    ..These data may be important for the genetics of mixed depression. The study aim was to investigate the BPFH of the hypomanic symptoms of mixed depression...
  19. ncbi Clinical differences between bipolar II depression and unipolar major depressive disorder: lack of an effect of age
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 75:191-5. 2003
    ..Age difference may be a confounding factor. Study aims were to describe the clinical and family history features of bipolar II versus unipolar depression, and to control for the possible confounding effect of age on clinical features...
  20. ncbi Refining the evaluation of bipolar II: beyond the strict SCID-CV guidelines for hypomania
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 73:33-8. 2003
    ..Our objective was to further refine the strict SCID-CV guidelines for hypomania in depressed outpatients...
  21. ncbi Bipolar II depressive mixed state: finding a useful definition
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Compr Psychiatry 44:21-7. 2003
    ..A cross-sectional marker like DMX3 may increase the probability of making the correct diagnosis of bipolar II, and therefore may be a useful definition of DMX...
  22. ncbi Depression with racing thoughts
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Res 120:273-82. 2003
    ..Depression with racing thoughts was very common in depressed outpatients, and was associated with suicidal ideation. Possible differential effects of antidepressants vs. mood stabilizers and antipsychotics are discussed...
  23. ncbi A continuity between bipolar II depression and major depressive disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 30:1043-50. 2006
    ..A bi-modal distribution would support a categorical distinction, and no bi-modality would support continuity...
  24. ncbi Mixed depression and the dimensional view of mood disorders
    Franco Benazzi
    Hecker Psychiatry Research Center and Department of Psychiatry, National Health Service, Forli, Italy
    Psychopathology 40:431-9. 2007
    ..The study aim was to test a dimensional approach to mood disorders by looking for a progressive grading of age at onset and bipolar family history loading between bipolar II disorder (BP-II) and major depressive disorder (MDD)...
  25. ncbi Inter-episode mood lability in mood disorders: residual symptom or natural course of illness?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna and the Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Clin Neurosci 58:480-6. 2004
    ....
  26. doi Does hypomania distinguish bipolar II disorder from major depressive disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center and Department of Psychiatry, National Health Service, Forli, Italy
    Psychother Psychosom 78:55-8. 2009
    ..The aim of the study was to test if hypomania could still be used to split categorically BP-II and MDD...
  27. ncbi Intra-episode hypomanic symptoms during major depression and their correlates
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Psychiatry Clin Neurosci 58:289-94. 2004
    ..Predicting the switch might have important treatment implications, because antidepressants used alone may worsen the course of bipolar disorders. Prospective studies are required to support these findings and hypotheses...
  28. ncbi Is there a continuity between bipolar and depressive disorders?
    Franco Benazzi
    Hecker Psychiatry Research Center, and Department of Psychiatry, National Health Service, Forli, Italy
    Psychother Psychosom 76:70-6. 2007
    ..Recent studies questioned the current categorical split of mood disorders into bipolar disorders (BP) and depressive disorders (MDD)...
  29. doi The modified SCID Hypomania Module (SCID-Hba): a detailed systematic phenomenologic probing
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    J Affect Disord 117:131-6. 2009
    ..Our interview follows DSM-IV criteria (apart from the minimum duration, 2 days versus DSM-IV 4 days), i.e. mood change must always been present, but our probing detects more hypomanic episodes than the SCID...
  30. pmc Various forms of depression
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    Dialogues Clin Neurosci 8:151-61. 2006
    ....
  31. ncbi Psychomotor changes in melancholic and atypical depression: unipolar and bipolar-II subtypes
    Franco Benazzi
    Department of Psychiatry, National Health Service, and Outpatient Psychiatry Private Center, Forli, Italy
    Psychiatry Res 112:211-20. 2002
    ..5 vs. 0.0%). Logistic regression controlling for age, gender and illness duration had little effect on the findings, which suggests that psychomotor changes are not core features of melancholic MDE...
  32. ncbi The dual factor structure of self-rated MDQ hypomania: energized-activity versus irritable-thought racing
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    J Affect Disord 73:59-64. 2003
    ..Bipolar II is diagnosed in a clinically depressed patient by documenting history of hypomania. Therefore, it is of great significance for both clinical and research purposes to characterize the factor structure of hypomania...
  33. ncbi Treating depressive mixed States in bipolar disorders
    Steven C Dilsaver
    Department of Psychiatry, National Health Service, Forli, Italy
    J Clin Psychiatry 69:e23. 2008
    ..Common treatment practices between the 2 paradigms include the art of adopting pharmacotherapeutic regimens that are tailored to the needs of each patient and frequent evaluation of the patient's progress...
  34. ncbi Bipolar II disorder : epidemiology, diagnosis and management
    Franco Benazzi
    Hecker Psychiatry Research Center, a University of California at San Diego USA Collaborating Center at Forli, Italy
    CNS Drugs 21:727-40. 2007
    ..Lamotrigine has shown some efficacy in delaying depression recurrences, but there have also been several negative unpublished studies of the drug in this indication...
  35. doi Olanzapine/fluoxetine combination for the treatment of mixed depression in bipolar I disorder: a post hoc analysis
    Franco Benazzi
    Hecker Psychiatry Research Center, Forli, Italy
    J Clin Psychiatry 70:1424-31. 2009
    ....
  36. ncbi Diagnosis of bipolar II disorder: a comparison of structured versus semistructured interviews
    Franco Benazzi
    Forli University of California at San Diego USA Collaborating Center, Forli, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 27:985-91. 2003
    ..The aim of the study was to find the degree of agreement in the diagnosis of BPII between the Structured Clinical Interview for DSM-IV (SCID) and a semistructured interview based on DSM-IV criteria done by an expert clinician...
  37. ncbi Highly recurrent unipolar may be related to bipolar II
    Franco Benazzi
    Department of Psychiatry, National Health Service, Forli, Italy
    Compr Psychiatry 43:263-8. 2002
    ..Pages and Dunner (1997) view that recurrent unipolar and bipolar II could be part of a single mood disorder, and Goodwin and Jamison (1990) view that recurrence is the key feature of mood disorders are partly supported by the findings...
  38. ncbi Mood patterns and classification in bipolar disorder
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego USA Collaborating Center, Forli, Italy
    Curr Opin Psychiatry 19:1-8. 2006
    ..The aim of this review is to highlight recent studies that have questioned the current split of mood disorders into the categories of bipolar and depressive disorders...
  39. ncbi Atypical depressive syndromes in varying definitions
    Jules Angst
    Zurich University Psychiatric Hospital, Lenggstrasse 31, PO Box 1931, 8032 Zurich, Switzerland
    Eur Arch Psychiatry Clin Neurosci 256:44-54. 2006
    ..Using prospective data from a community sample, this paper identifies criteria (and correlates) for an AD syndrome that maximizes the association with female sex and bipolar-II...
  40. ncbi Melancholic outpatient depression in Bipolar-II vs. unipolar
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 28:481-5. 2004
    ..DSM-IV melancholic major depressive episode (MDE) in bipolar II disorder (BP-II) is understudied. Study aim was to compare melancholic MDE in BP-II vs. unipolar major depressive disorder (MDD) on diagnostic validators and clinical features...
  41. ncbi Validating Angst's "ups & downs" personality trait as a new marker of bipolar II disorder
    Franco Benazzi
    Via Pozzetto 17, 48010 Castiglione di Cervia RA, Italy
    Eur Arch Psychiatry Clin Neurosci 254:48-54. 2004
    ..Study aim was to find the frequency of "ups & downs" in a large sample of bipolar II (BPII) and major depressive disorder (MDD),and to test its association with BPII...
  42. ncbi Major depressive disorder with anger: a bipolar spectrum disorder?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California, San Diego, Calif, USA
    Psychother Psychosom 72:300-6. 2003
    ..The aim of the study was to assess whether major depressive disorder (MDD) with anger could be included in the bipolar spectrum, by comparing it to MDD without anger and to bipolar II disorder...
  43. ncbi Testing DSM-IV definition of atypical depression
    Franco Benazzi
    Outpatient Psychiatry Center, University of California at San Diego, USA
    Ann Clin Psychiatry 15:9-16. 2003
    ..All AD symptoms were significantly associated with DSM-IV AD, and with most study variables. Results support the current DSM-IV definition of AD...
  44. ncbi Anger in bipolar depression
    Franco Benazzi
    J Clin Psychiatry 64:480-1; author reply 481. 2003
  45. ncbi Reviewing the diagnostic validity and utility of mixed depression (depressive mixed states)
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, San Diego, CA, USA
    Eur Psychiatry 23:40-8. 2008
    ..To review the diagnostic validity and utility of mixed depression, i.e. co-occurrence of depression and manic/hypomanic symptoms...
  46. ncbi Is there a link between atypical and early-onset "unipolar" depression and bipolar II disorder?
    Franco Benazzi
    Outpatient Psychiatry Center, a University of California San Diego Collaborating Center, Ravenna and Forli, and Department of Psychiatry, National Health Service of Forlì, Italy
    Compr Psychiatry 44:102-9. 2003
    ..These results support a link of atypical and early-onset "unipolar" depression with bipolar II disorder, and support Pages and Dunner's suggestion to combine bipolar II and recurrent unipolar into a single group...
  47. ncbi The Mood Disorder Questionnaire for assessing bipolar spectrum disorder frequency
    Franco Benazzi
    Can J Psychiatry 47:386-7. 2002
  48. ncbi Can only reversed vegetative symptoms define atypical depression?
    Franco Benazzi
    Outpatient Psychiatry Center, Ravenna and Forli, Italy
    Eur Arch Psychiatry Clin Neurosci 252:288-93. 2002
    ....
  49. ncbi Bipolar II depressive mixed state changes with age
    Franco Benazzi
    J Affect Disord 73:295-7. 2003
  50. doi A relationship between bipolar II disorder and borderline personality disorder?
    Franco Benazzi
    University of California at San Diego, United States
    Prog Neuropsychopharmacol Biol Psychiatry 32:1022-9. 2008
    ..The relationship between DSM-IV-TR borderline personality disorder (BPD) and bipolar disorders, especially bipolar II disorder (BP-II), is still unclear. Many recent reviews on this topic have come to opposite or different conclusions...
  51. doi Differential patterns of lifetime multiple anxiety disorder comorbidity between Latino adults with bipolar I and major depressive disorders
    Steven C Dilsaver
    Comprehensive Doctors Medical Group Inc, Arcadia, California and the Rio Grande City Community Mental Health Mental Retardation Clinic, Rio Grande City, Texas, USA
    Bull Menninger Clin 72:130-48. 2008
    ....
  52. ncbi Toward a re-definition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar-II, minor bipolar disorders and hypomania
    Jules Angst
    Zurich University Psychiatric Hospital, Lenggstrasse 31, P O Box 68, CH 8029, Zurich, Switzerland
    J Affect Disord 73:133-46. 2003
    ..to develop and validate criteria for the definition of softer expressions of bipolar-II (BP-II) disorder and hypomania, (3). to demonstrate the prevalence, clinical validity and comorbidity of the entire soft bipolar spectrum...
  53. ncbi Which could be a clinically useful definition of depressive mixed state?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California in San Diego USA Collaborating Center, San Diego, CA, USA
    Prog Neuropsychopharmacol Biol Psychiatry 26:1105-11. 2002
    ..Study aim was to find if the best clinically useful definition of DMX was one based on a minimum number of hypomanic symptoms, or instead one based on the combination of specific hypomanic symptoms...
  54. ncbi Agitated depression: unipolar? Bipolar? Or both?
    Franco Benazzi
    Outpatient Psychiatry Center, University of California, San Diego, USA
    Ann Clin Psychiatry 14:97-104. 2002
    ..Further studies on this topic are needed...
  55. ncbi Should mood reactivity be included in the DSM-IV atypical features specifier?
    Franco Benazzi
    Eur Arch Psychiatry Clin Neurosci 252:135-40. 2002
    ..The study aim was to test whether mood reactivity should be included in DSM-IV atypical features specifier...
  56. ncbi Is depressive mixed state a transition between depression and hypomania?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Eur Arch Psychiatry Clin Neurosci 254:69-75. 2004
    ..Study aim was to find if DMX in bipolar II disorder was often a transition period between depression and hypomania, as suggested by Kraepelin...
  57. ncbi Post-traumatic stress disorder among adolescents with bipolar disorder and its relationship to suicidality
    Steven C Dilsaver
    Mental Health Mental Retardation Clinic, Rio Grande City, TX, USA
    Bipolar Disord 9:649-55. 2007
    ..The impetus for the study was born of clinical impressions derived in the course of routine clinical practice...
  58. ncbi Testing atypical depression definitions
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Int J Methods Psychiatr Res 14:82-91. 2005
    ..Pharmacological studies are required to support any new definition of AD, as the current concept of AD is based on different response to TCA antidepressants versus non-AD...
  59. ncbi Unipolar depression with racing thoughts: a bipolar spectrum disorder?
    Franco Benazzi
    University of California at San Diego, USA, and Hecker Psychiatry Research Center, Ravenna, Italy
    Psychiatry Clin Neurosci 59:570-5. 2005
    ....
  60. ncbi Optimizing the detection of bipolar II disorder in outpatient private practice: toward a systematization of clinical diagnostic wisdom
    Hagop S Akiskal
    International Mood Center, University of California, San Diego, USA
    J Clin Psychiatry 66:914-21. 2005
    ....
  61. ncbi Gender differences in bipolar-II disorder
    Franco Benazzi
    Eur Arch Psychiatry Clin Neurosci 256:67-71. 2006
    ..Gender differences in bipolar-II disorder (BP-II) are understudied...
  62. ncbi The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, VA Psychiatry Service, 116A, 3350 La Jolla Village Drive, 92161, USA
    J Affect Disord 92:45-54. 2006
    ..We used the ongoing Ravenna-San Diego Collaboration database to examine this question with respect to major depressive disorder (MDD) and bipolar II (BP-II)...
  63. ncbi Possible bipolar nature of irritability in major depressive disorder
    Franco Benazzi
    J Clin Psychiatry 66:1072; author reply 1073. 2005
  64. ncbi Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy
    Hagop S Akiskal
    Department of Psychiatry and International Mood Center, University of California, La Jolla, CA, USA
    J Affect Disord 85:245-58. 2005
    ..S., Mallya, G., 1987. Criteria for the "soft" bipolar spectrum: treatment implications. Psychopharmacol Bull. 23, 68-73]...
  65. ncbi Is overactivity the core feature of hypomania in bipolar II disorder?
    Franco Benazzi
    Hecker Psychiatry Research Center, University of California at San Diego, San Diego, CA, USA
    Psychopathology 40:54-60. 2007
    ..The aim of the study was to find out if overactivity was at least as important as mood change for the diagnosis of hypomania...
  66. ncbi Atypical depression: a variant of bipolar II or a bridge between unipolar and bipolar II?
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, V A Hospital, 3350 La Jolla Village Dr 116 A, La Jolla, San Diego, CA 92161, USA
    J Affect Disord 84:209-17. 2005
    ..Accordingly, we undertook a full scale validation of such a link in a large clinical sample of BP-II and unipolar (UP) major depressive disorder (MDD)...
  67. ncbi Depressive mixed state: a feature of the natural course of bipolar II (and major depressive) disorder?
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Psychopathology 37:207-12. 2004
    ..Kraepelin observed, in an inpatient sample, that DMX was related to the number of episodes and to duration of manic-depressive insanity (illness)...
  68. ncbi Anger in depressive mixed states
    Franco Benazzi
    J Clin Psychiatry 65:1578-9; author reply 1579. 2004
  69. ncbi Psychopathologic correlates of suicidal ideation in major depressive outpatients: is it all due to unrecognized (bipolar) depressive mixed states?
    Hagop S Akiskal
    International Mood Center, University of California at San Diego, Calif 92161, USA
    Psychopathology 38:273-80. 2005
    ..Recent transatlantic concern about suicidality in patients receiving antidepressants prompted us to examine the psychopathologic correlates of suicidal ideation occurring in clinically depressed patients...
  70. ncbi Mixed depression, suicidality, and antidepressants
    Franco Benazzi
    J Clin Psychiatry 67:1650-1; author reply 1650-1. 2006
  71. ncbi Family history validation of a definition of mixed depression
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Compr Psychiatry 46:159-66. 2005
    ..The study aim was to test different definitions of mixed depression, defined as a depression with concurrent hypomanic symptoms...
  72. ncbi Atypical depression: category or specifier?
    Franco Benazzi
    J Clin Psychiatry 67:996-7; author reply 997. 2006
  73. ncbi Testing early-onset chronic atypical depression subtype
    Franco Benazzi
    Neuropsychopharmacology 29:440-1. 2004
  74. ncbi Gender, suicidality and bipolar mixed states in adolescents
    Steven C Dilsaver
    Community Mental Health Clinic, Rio Grande City, TX, USA
    J Affect Disord 87:11-6. 2005
    ..The purpose of this study was to determine the relationship between mixed states and suicidality among adolescent outpatients presenting with a DSM-IV defined major depressive episode (MDE)...
  75. ncbi Mixed depression: a clinical marker of bipolar-II disorder
    Franco Benazzi
    E Hecker Outpatient Psychiatry Center, Ravenna, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 29:267-74. 2005
    ..Study aim was to test the predictive power for the diagnosis of BP-II of several dimensional definitions of mixed depression, searching for a clinical marker which could reduce the current underdiagnosis of BP-II...
  76. ncbi A cross-sectional study of the prevalence of cognitive and physical symptoms during long-term antidepressant treatment
    Maurizio Fava
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    J Clin Psychiatry 67:1754-9. 2006
    ..The purpose of the present work is to examine cross-sectionally the prevalence of cognitive and physical side effects of antidepressants during long-term treatment of depression...