Giuseppe Di Pasquale

..The hope for the future is the development of new selective platelet inhibitors with higher antischemic efficacy and better hemorrhagic profile...

..AF can induce HF and persistence over time of high rate AF may result in tachycardiomyopathy, a form of dilated cardiomyopathy characterized by severe left ventricular dysfunction...

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..Percutaneous closure of patent foramen does not seem to be superior to medical therapy for the prevention of recurrences in patients with cryptogenic stroke...

..The promise of new oral anticoagulants gives us the hope that warfarin will finally be replaced in a near future, but more importantly that anticoagulant undertreatment of atrial fibrillation will be partially overcome...

..To analyse discharge prescription of recommended treatments in patients with ST-segment elevation myocardial infarction (STEMI) according to reperfusion strategies...

..As a consequence, clues for the optimal management of this patient subset will be obtained...

..Therefore, large-scale prospective studies are needed to determine the optimal antithrombotic treatment in this patient population...

..Therefore, clinical trials addressing this relevant pathologic condition are urgently needed...

..Therefore, the role of the Scientific Societies is to improve the application of guidelines and the utilization of all evidence-based treatments even in such post-discharge phase...

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..We report our experience with atrial transseptal puncture carried out during an electrophysiological procedure in patients with prosthetic valves...

..Unfortunately, these bleeding complications have a negative prognostic significance and force clinicians to suspend (or decrease) the antithrombotic treatments to control bleeding...

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..This holds particularly true for patients with ACS undergoing percutaneous revascularization...

..At present more than 250 patients have been implanted, and the results, as far as the safety and the effectiveness are concerned, are really promising. We report 2 cases of recently successfully implanted at our Center...

..Also, the contribution of early bleeding to the relevant hemorrhagic rate reported at follow-up with triple therapy of OAC, aspirin, and clopidogrel is largely unknown...

..Therefore, it is essential the balance between the ischemic and hemorrhagic risk...

..In the reported case, the treatment with thrombolysis and subsequent heparin infusion was effective and safe. We discuss the rationale for this treatment in the light of literature data...

..To verify the reliability of the surface ECG to discriminate between cavotricuspid isthmus-dependent atrial flutter (CTI-AFL) and non-CTI-AFL...

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..is NSTEMI rather than a "masked" dorsal STEMI? Which coronary substrate and what ischemia extension can we hypothesize in this patient? In particular, is the substrate of such high risk suggesting an emergency invasive approach?..

..We present a case of traumatic syncope during an epileptic disorder ab esordio and we discuss the related literature...

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..The aim of our study was to determine the strategies adopted at our Institution (where the management of these patients is at the physician's discretion), and to evaluate their relative efficacy and safety...

..Along with its easiness of use, not requiring laboratory monitoring, the subcutaneous administration of enoxaparin allows extended antithrombotic treatment, while permitting early mobilization (and rehabilitation) of patients...

..At presentation, pleural effusion, troponin positivity, acute coronary syndrome-like electrocardiogram, and dyspnea are possible "clinical confounders" associated with particularly long in-hospital diagnostic times...

..Therefore, both the University and the Scientific Societies should re-design the training process of the cardiologists working in the CCUs...

..3; P<.0001). In conclusion, real-world warfarin patients undergoing PCI-S are largely managed according to the current recommendations. As a consequence, the risk of in-hospital MACE and major bleedings appears limited and acceptable...

..This could reduce treatment disparities and could counteract the vicious circle that tends to privilege interventions in low-risk subjects instead of high-risk patients, like the elderly, women or diabetics...

..The available data suggest that a combined surgical and percutaneous approach could be the strategy of choice...

..These approaches will likely provide new insights into the pathophysiology of acute coronary events and into the effects of aggressive preventive therapies...