Renata Auricchio

Summary

Country: Italy

Publications

  1. ncbi request reprint In vitro-deranged intestinal immune response to gliadin in type 1 diabetes
    Renata Auricchio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Diabetes 53:1680-3. 2004
  2. pmc Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular trafficking
    M Vittoria Barone
    Department of Pediatrics, European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Naples, Italy
    PLoS ONE 6:e17039. 2011
  3. doi request reprint An undigested gliadin peptide activates innate immunity and proliferative signaling in enterocytes: the role in celiac disease
    Merlin Nanayakkara
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Disease, University of Naples, Federico II, Naples, Italy, and the Department of Medicine, University of Chicago, Chicago, IL
    Am J Clin Nutr 98:1123-35. 2013
  4. doi request reprint Intestinal deposits of anti-tissue transglutaminase IgA in childhood celiac disease
    Mariantonia Maglio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Dig Liver Dis 43:604-8. 2011
  5. doi request reprint Serum and intestinal celiac disease-associated antibodies in children with celiac disease younger than 2 years of age
    Mariantonia Maglio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 50:43-8. 2010
  6. doi request reprint Immunoglobulin A anti-tissue transglutaminase antibody deposits in the small intestinal mucosa of children with no villous atrophy
    Antonella Tosco
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 47:293-8. 2008
  7. pmc Majority of children with type 1 diabetes produce and deposit anti-tissue transglutaminase antibodies in the small intestine
    Mariantonia Maglio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Diabetes 58:1578-84. 2009
  8. ncbi request reprint Gluten sensitivity in a subset of children with insulin dependent diabetes mellitus
    Riccardo Troncone
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Am J Gastroenterol 98:590-5. 2003
  9. doi request reprint Natural history of potential celiac disease in children
    Antonella Tosco
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Clin Gastroenterol Hepatol 9:320-5; quiz e36. 2011
  10. pmc Enterocyte proliferation and signaling are constitutively altered in celiac disease
    Merlin Nanayakkara
    Department of Traslational Medicine section of Pediatrics and ELFID European Laboratory for the Investigation of Food Induced Disease, University of Naples, Federico II, Naples, Italy
    PLoS ONE 8:e76006. 2013

Collaborators

  • Salvatore Auricchio
  • Gaetano Terrone
  • Giuseppe Mazzarella
  • Carmen Gianfrani
  • Annamaria Staiano
  • Maria de Angelis
  • M Vittoria Barone
  • Carla Esposito
  • Giuliana Valerio
  • Bana Jabri
  • Daniele Sblattero
  • R Troncone
  • A Franzese
  • Anna Sannino
  • Mariantonia Maglio
  • Luigi Greco
  • Antonella Tosco
  • Merlin Nanayakkara
  • Francesco Paparo
  • Erasmo Miele
  • Giuliana Lania
  • Martina Galatola
  • Marco Sarno
  • Alessandra Gaito
  • Melissa Borrelli
  • Maria Pia Sperandeo
  • Delia Zanzi
  • Luciano Rapacciuolo
  • Roberta Kosova
  • Valentina Discepolo
  • Valentina Izzo
  • Barbara Colicchio
  • Maria Maglio
  • Jihane Romanos
  • Alienke J Monsuur
  • Marinita Morelli
  • Katia Ferrara
  • Sara Santagata
  • Marialaura Cuomo
  • Domenico Ponticelli
  • Giuseppina Gambino
  • Caterina Strisciuglio
  • Rosita Aitoro
  • Donatella Cielo
  • Virginia M Salvati
  • Massimo Boffardi
  • Angela Cassone
  • Gosia Trynka
  • Virginia Michela Salvati
  • Basilio Malamisura
  • Antonella Esposito
  • Anna Coruzzo
  • Raffaella Di Mase
  • Marco Gobbetti
  • Francesca Landolfo
  • Carlo Giuseppe Rizzello
  • Francesca Tucci
  • Martina D'Aniello
  • Raffaella di Cagno
  • Laura Timpone
  • Grazia D'Adamo
  • Viviana Granata
  • Viviana Indolfi
  • Monica Vecchiet
  • Roberto Marzari
  • Raffaella Spadaro
  • Fiorella Florian
  • J Bart A Crusius
  • Cisca Wijmenga
  • Willem Verduijn
  • Alexandra Zhernakova
  • Ana Lopez
  • Paul I W de Bakker
  • David A van Heel
  • Dalila Pinto
  • Steven J Novek
  • Domenico Simeone
  • Antonio Marino
  • Arturo Tozzi

Detail Information

Publications23

  1. ncbi request reprint In vitro-deranged intestinal immune response to gliadin in type 1 diabetes
    Renata Auricchio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Diabetes 53:1680-3. 2004
    ..In conclusion, signs of mucosal inflammation were present in jejunal biopsies from type 1 diabetic patients, and organ culture studies indicate a deranged mucosal immune response to gliadin...
  2. pmc Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular trafficking
    M Vittoria Barone
    Department of Pediatrics, European Laboratory for the Investigation of Food Induced Diseases, University of Naples Federico II, Naples, Italy
    PLoS ONE 6:e17039. 2011
    ..Aims of this study were to investigate the role of P31-43 in the induction of cellular proliferation and innate immune activation...
  3. doi request reprint An undigested gliadin peptide activates innate immunity and proliferative signaling in enterocytes: the role in celiac disease
    Merlin Nanayakkara
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Disease, University of Naples, Federico II, Naples, Italy, and the Department of Medicine, University of Chicago, Chicago, IL
    Am J Clin Nutr 98:1123-35. 2013
    ..The effects of gliadin on crypt enterocyte proliferation and activation of innate immunity are mediated by epidermal growth factors (EGFs) and innate immunity mediators [interleukin 15 (IL15)]...
  4. doi request reprint Intestinal deposits of anti-tissue transglutaminase IgA in childhood celiac disease
    Mariantonia Maglio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Dig Liver Dis 43:604-8. 2011
    ..High serum levels of anti-tissue-transglutaminase-2 IgA antibodies (anti-TG2), which are produced and deposited in the intestine, characterize celiac disease...
  5. doi request reprint Serum and intestinal celiac disease-associated antibodies in children with celiac disease younger than 2 years of age
    Mariantonia Maglio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 50:43-8. 2010
    ....
  6. doi request reprint Immunoglobulin A anti-tissue transglutaminase antibody deposits in the small intestinal mucosa of children with no villous atrophy
    Antonella Tosco
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 47:293-8. 2008
    ..The aim of this study was to look for anti-TG2 IgA deposits in the intestine of children with normal villous architecture and to relate them with other markers of gluten sensitivity...
  7. pmc Majority of children with type 1 diabetes produce and deposit anti-tissue transglutaminase antibodies in the small intestine
    Mariantonia Maglio
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Diabetes 58:1578-84. 2009
    ..Given the close association between celiac disease and type 1 diabetes, we investigated the production and deposition of anti-TG2 antibodies in the jejunal mucosa of type 1 diabetic children...
  8. ncbi request reprint Gluten sensitivity in a subset of children with insulin dependent diabetes mellitus
    Riccardo Troncone
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Am J Gastroenterol 98:590-5. 2003
    ..The aim of this study was to assess the mucosal immune response to gluten in IDDM children by rectal gluten challenge...
  9. doi request reprint Natural history of potential celiac disease in children
    Antonella Tosco
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Clin Gastroenterol Hepatol 9:320-5; quiz e36. 2011
    ..We performed a prospective, 3-year cohort study to determine the natural history of potential celiac disease in children...
  10. pmc Enterocyte proliferation and signaling are constitutively altered in celiac disease
    Merlin Nanayakkara
    Department of Traslational Medicine section of Pediatrics and ELFID European Laboratory for the Investigation of Food Induced Disease, University of Naples, Federico II, Naples, Italy
    PLoS ONE 8:e76006. 2013
    ..This observation potentially explains the specificity of the damaging effects of certain gliadin peptides on CD intestine. ..
  11. pmc A Celiac Cellular Phenotype, with Altered LPP Sub-Cellular Distribution, Is Inducible in Controls by the Toxic Gliadin Peptide P31-43
    Merlin Nanayakkara
    Department of Translational Medical Science, University of Naples Federico II, Naples, Italy European Laboratory for the Investigation of Food Induced Disease, ELFID University of Naples Federico II, Naples, Italy
    PLoS ONE 8:e79763. 2013
    ....
  12. doi request reprint Immunoregulatory pathways are active in the small intestinal mucosa of patients with potential celiac disease
    Melissa Borrelli
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Am J Gastroenterol 108:1775-84. 2013
    ..The objective of this study was to investigate in the small intestinal mucosa of such patients the state of immunological activation with special emphasis on immunoregulatory circuits...
  13. doi request reprint Italian paediatricians' approach to coeliac disease diagnosis
    Renata Auricchio
    Department of Pediatrics, University Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 49:374-6. 2009
    ..In conclusion, ESPGHAN criteria are widely followed by Italian CD centres. However, their revision may be useful, but it should be evidence based. Large, multicentre studies are greatly needed...
  14. doi request reprint Safety for patients with celiac disease of baked goods made of wheat flour hydrolyzed during food processing
    Luigi Greco
    Department of Pediatrics and European Laboratory for the Study of Food Induced Diseases, University of Naples, Federico II, Naples, Italy
    Clin Gastroenterol Hepatol 9:24-9. 2011
    ..We evaluated the safety of daily administration of baked goods made from this hydrolyzed form of wheat flour to patients with CD...
  15. pmc Potential celiac patients: a model of celiac disease pathogenesis
    Maria Pia Sperandeo
    European Laboratory for Food Induced Disease, University of Naples Federico II, Naples, Italy
    PLoS ONE 6:e21281. 2011
    ..The aim of the study is to explore the genetic features of Potential CD individuals...
  16. pmc Gliadin peptide P31-43 localises to endocytic vesicles and interferes with their maturation
    Maria Vittoria Barone
    Pediatric Department and European Laboratory for the Investigation of Food Induced Disease, University of Naples Federico II, Naples, Italy
    PLoS ONE 5:e12246. 2010
    ..These effects are mediated by delayed EGFR degradation and prolonged EGFR activation in endocytic vesicles. In the present study we investigated the effects of gliadin peptides on the trafficking and maturation of endocytic vesicles...
  17. doi request reprint The Pediatric Symptom Checklist as screening tool for neurological and psychosocial problems in a paediatric cohort of patients with coeliac disease
    Gaetano Terrone
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    Acta Paediatr 102:e325-8. 2013
    ..To screen for neurological and behavioural disorders in a paediatric cohort of patients with coeliac disease (CD) in order to detect possible differences related to compliance with gluten-free diet (GFD)...
  18. pmc Gene expression profile of peripheral blood monocytes: a step towards the molecular diagnosis of celiac disease?
    Martina Galatola
    Department of Translational Medical Science, University of Naples Federico II, Naples, Italy European Laboratory for Food Induced disease ELFID, University of Naples Federico II, Naples, Italy Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy
    PLoS ONE 8:e74747. 2013
    ..Then, using multivariant discriminant analysis, we evaluated whether the expression profiles of these genes in peripheral blood monocytes (PBMs) differed between patients and controls...
  19. doi request reprint Issues related to gluten-free diet in coeliac disease
    Riccardo Troncone
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy
    Curr Opin Clin Nutr Metab Care 11:329-33. 2008
    ..This review describes the latest progress in research concerning treatment with gluten-free diet in patients with coeliac disease...
  20. ncbi request reprint Functional gastrointestinal disorders in children: an Italian prospective survey
    Erasmo Miele
    Department of Pediatrics, University Federico II, Naples, Italy
    Pediatrics 114:73-8. 2004
    ..To assess the prevalence and natural history of functional gastrointestinal disorders (FGIDs) in children using the Rome Criteria...
  21. ncbi request reprint Coeliac disease and extraintestinal autoimmunity
    Riccardo Troncone
    Department of Pediatrics and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Via S Pansini 5, I 80131 Naples, Italy
    J Pediatr Gastroenterol Nutr 39:S740-1. 2004
  22. ncbi request reprint Clinical response to amino acid-based formula in neurologically impaired children with refractory esophagitis
    Erasmo Miele
    Department of Pediatrics and European Laboratory for the Invstigation of Food Induced Diseases, University Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 35:314-9. 2002
    ..The aim of our study was to evaluate the efficacy of a dietary trial in neurologically impaired children unresponsive to medical and surgical therapy for GERD...
  23. pmc Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms
    Alienke J Monsuur
    Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands
    PLoS ONE 3:e2270. 2008
    ..However, current genotyping methods for HLA risk factors involve many reactions, and are complicated and expensive. We sought a simple experimental approach using tagging SNPs that predict the CD-associated HLA risk factors...