Giuseppe Argenziano

..The starburst pattern is the dermoscopic hallmark of pigmented Spitz nevus, although it has been rarely observed in melanoma as well...

..We report 2 patients with EP and discuss the diagnostic significance of the observed dermoscopic findings...

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..Recently we reported the usefulness of epiluminescence microscopy (dermatoscopy) for in vivo detection of the phases of melanoma progression, as well as tumor depth...

..A large pedigree comprising 6 generations with 20 members affected by Marie Unna hypotrichosis from Italy is reported...

..To describe the different vascular structures seen by dermoscopy and to evaluate their association with various melanocytic and nonmelanocytic skin tumors in a large series of cases...

..Dermoscopy has been shown to increase the diagnostic accuracy of clinically equivocal lesions, but little is known about its ability to detect melanoma in the context of lesions that appear clinically benign...

..The aim of this randomized study was to determine whether the adjunct of dermoscopy to the standard clinical examination improves the accuracy of PCPs to triage lesions suggestive of skin cancer...

..Teledermoscopy represents a useful tool for the diagnosis of acral melanoma and for the categorization of patterns that suggest benign or potentially malignant acral melanocytic lesions...

..The value of total body skin examination (TBSE) for skin cancer screening is controversial...

..CONCLUSIONS: Teleconsultation of dermoscopic images of pigmented skin lesions via e-mail provides a similar degree of diagnostic accuracy as face-to-face diagnosis when the diagnosis is made by a dermatologist confident with dermoscopy...

..Early detection of basal cell carcinoma (BCC) is crucial to reduce the morbidity of this tumor...

..To investigate changes in dermoscopic patterns of acquired acral melanocytic nevi (AAMN) over time...

..53). CONCLUSION: The virtual Consensus Net Meeting on Dermoscopy represents a valid tool for better standardization of the dermoscopic terminology and, moreover, opens up a new territory for diagnosing and managing pigmented skin lesions...

..Recent studies demonstrating accuracy of teledermatology and teledermoscopy in the evaluation of pigmented skin lesions (PSL) have been performed only on PSL previously selected by face-to-face examination...

..Development of melanocytic nevi is a complex process...

..We discuss the advantages and limitations of this technique in this particular field of application...

..Finally, a hint to the use of cytodiagnosis for basal cell carcinoma is provided...

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..A 62-year-old man presented with the unusual association of acrokeratosis verruciformis of Hopf and multiple keratoacanthomas. Both conditions were treated successfully with acitretin...

..To assess the outcome on management recommendations of a comparative approach vs a morphologic approach in evaluating dermoscopic images of lesions from a series of patients with multiple nevi...

..Little is known about the possible influence of associated clinical features on the reliability of dermoscopic diagnosis during in vivo examination...

..Herein we describe the clinical, dermoscopic and histopathological findings in a patient affected by GF and its response to long-term topical treatment with tacrolimus 0.1% cream...

..In addition, conflicting data are available on other potential low-penetrance genes encoding proteins involved in pigmentation, cell growth and differentiation, DNA repair or detoxifying of metabolites...

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..CONCLUSION: Dermoscopy and digital follow up might be the key factors to improve the knowledge about the natural evolution of nevi and melanoma and the spectrum of undefined melanocytic proliferations...

..The aim of this study was to investigate the effectiveness of acitretin in a new topical formulation (mucoadhesive two-layer tablets) for the treatment of oral leucoplakias...

..A definite hypodiploid peak was associated with worse prognosis. The analysis of cyclin D1 expression and DNA ploidy may help identify BCC with an aggressive phenotype and a poor clinical outcome...

..However, the term 'dermoscopy', first used by Friedman and colleagues in 1991, is the most widely used...

..We initially evaluated five cases and found that none had baseline features suggestive of melanoma; excision was performed based on slight changes visible only in side-by-side comparisons of dermoscopic images...

..After a five year follow up no more lesions were observed. The histopathological examination, immunohistochemical profile and electron microscopy of the lesions indicated Langerhans cell histiocytosis...

..5% of SECN. Histopathologically, this network corresponds to focal areas of pigmented parakeratosis, producing a black reticulated appearance on the horizontal plane...

..CONCLUSIONS: We demonstrated that Web-based training is an effective tool for teaching dermoscopy...

..CONCLUSION: We think that the gray-whitish veil is a distinctive dermoscopic feature that is able to differentiate between superficial vessels (absence of veil) and deeper vessels (presence of veil)...

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..We also classified small- and medium-sized congenital naevi (CN) into nine subtypes according to their macroscopic and dermoscopic aspects...

..To assess whether multiple observers can identify the same pigmented lesion(s) as being different from a patient's other moles ("ugly duckling" [UD] sign) and to explore whether the UD sign is sensitive for melanoma detection...

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..To determine the time required to perform a complete skin examination (CSE) as a means of opportunistic screening for skin cancer both without and with dermoscopy...

..The objective was to describe the clinical and dermoscopic characteristics of difficult-to-diagnose melanomas (DDM)...

..To determine the predictive dermoscopic features of amelanotic and hypomelanotic melanoma...

..These remarkable differences could be explained by a dual concept of nevogenesis, based on current clinico-epidemiologic, dermoscopic, histopathologic and genetic data...

..We report a 42-year-old woman who presented with a recurrent and metastatic melanoma after laser treatment of a tumor which was apparently clinically innocent and highlight the clinical features of such benign-looking melanomas...

..These also achieved good detection accuracy as indicated by their AUC values: 0.985, 0.931, and 0.890, respectively. The features used in the melanoma-nevus classifier and the parallel ridge detector have significant overlap...

..Dermoscopic classification of acquired melanocytic nevi (AMN) is based on the evaluation of 3 main criteria-global pattern, pigment distribution, and color...

..In contrast to the dermoscopic features usually seen in melanoma occurring on the face, the same morphologic type of pigment network usually seen in melanoma of the trunk was observed in our case of scalp melanoma...

..75 mm) and Clark naevi, and 73.9 and 85.6%, respectively, for discriminating between melanoma in situ and Clark naevi. Our algorithm accurately discriminated invasive melanomas from Clark naevi, but not melanomas in situ from Clark naevi...

..In this case step-sections of the sample were deemed to be required for definite diagnosis. The combined approach was helpful in detecting macroscopic and microscope sampling errors of melanocytic lesions during teleconsultation...

..Thus it may be applied as a screening procedure for the early detection of melanoma...

..Lesions showing clear-cut regression structures are prone to give some histopathologic disagreement...

..Based on our observation, the globular and the starburst patterns might be considered different morphologic expressions corresponding to the evolutionary phases of pigmented Spitz nevi...

..The first step in the dermoscopic evaluation is the differentiation between melanocytic and nonmelanocytic skin tumors...

..While the dermoscopic features of basal cell carcinoma have been studied extensively, little is known about the dermoscopic features of FeP...

..Our findings confirm that CBN is a distinctive variant of blue nevus that may mimic cutaneous melanoma both clinically and dermoscopically...

..We report an acral congenital melanocytic nevus typified by the presence of three different dermoscopic patterns that are commonly seen in acquired melanocytic nevi of palms and soles...

..In recent years, several histopathologic variants of blue nevus have been identified, whose clinical and dermoscopic correlates need further clarification...

..Asymmetry should be assessed using both dermoscopic and histopathologic analysis, and reliability in histopathologic diagnosis may be enhanced by the simultaneous evaluation of the corresponding dermoscopic images...