Research Topics
Species | F AndreottiSummaryCountry: Italy Publications
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Detail Information
Publications
[Pathophysiology of ischemic heart disease in women]Felicita Andreotti
Dipartimento di Medicina Cardiovascolare, Policlinico Universitario A Gemelli, Roma
G Ital Cardiol (Rome) 13:396-400. 2012....
Homocysteine and arterial occlusive disease: a concise reviewF Andreotti
Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Roma
Cardiologia 44:341-5. 1999..Family studies may also provide evidence of causality if genetic causes of hyperhomocysteinemia are found to segregate with disease...
Sex, survival bias, and mortality following acute myocardial infarctionFelicita Andreotti
Istituto di Cardiologia Università Cattolica del Sacro Cuore Policlinico A Gemelli Largo A Gemelli, 8 00168 Roma
Ital Heart J 4:508-10. 2003..Taken together, the above findings suggest that, following acute MI, significant gender differences lie not so much in overall mortality, but in the timing and mechanisms of death...
[Body mass index and cardiovascular events: the "obesity paradox"]Felicita Andreotti
Istituto di Cardiologia, Dipartimento di Medicina Cardiovascolare, Policlinico Universitario A Gemelli, Roma
Recenti Prog Med 100:447-50. 2009....
Update on phase II studies of erythropoietin in acute myocardial infarction. Rationale and design of Exogenous erythroPoietin in Acute Myocardial Infarction: New Outlook aNd Dose Association Study (EPAMINONDAS)Felicita Andreotti
Institute of Cardiology, Department of Cardiovascular Medicine, A Gemelli University Hospital, Largo Gemelli 8, 00168, Rome, Italy
J Thromb Thrombolysis 28:489-95. 2009..The results of current phase II studies will help define the safety/efficacy profile of Epo for patients with STEMI...
Potentiation of fibrinolytic therapy in acute myocardial infarction: expanding the role of ACE-inhibitorsFelicita Andreotti
Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
Thromb Haemost 88:176-8. 2002
Contrast-induced nephropathy and mortality: possible crucial role of asymmetric dimethylarginineFelicita Andreotti
Department of Cardiovascular Medicine, Catholic University, Rome, Italy
J Cardiovasc Med (Hagerstown) 8:1043. 2007
Acute coronary syndromes in women: pathophysiology and therapeutic optionsF Andreotti
Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Policlinico Agostino Gemelli, Largo Agostino Gemelli, 8, 00168 Roma
Cardiologia 44:511-4. 1999..Moreover, revascularization procedures and several anti-ischemic drugs appear underutilized in women...
Circadianicity of hemostatic function and coronary vasomotionF Andreotti
Istituto di Cardiologia Università Cattolica del Sacro Cuore Policlinico Agostino Gemelli Largo Agostino Gemelli, 8, 00168 Roma
Cardiologia 44:245-9. 1999....
Women and coronary diseaseFelicita Andreotti
Department of Cardiovascular Medicine, Catholic University Medical School, Rome, Italy
Heart 94:108-16. 2008
[Recent advances in atherothrombotic diseases]Felicita Andreotti
Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Roma
Recenti Prog Med 97:183-8. 2006..Acquired thrombophilias that should be searched for include the antiphospholipid syndrome, systemic lupus erythematosus, and myeloproliferative disorders...
The strengths and frailties of women with cardiovascular diseaseFelicita Andreotti
, 8 00168 Roma, Italy
Ital Heart J 4:361-2. 2003
Aspirin plus warfarin compared to aspirin alone after acute coronary syndromes: an updated and comprehensive meta-analysis of 25,307 patientsFelicita Andreotti
Institute of Cardiology, Catholic University, Largo F Vito, 00168, Rome, Italy
Eur Heart J 27:519-26. 2006..We conducted a specific meta-analysis of randomized trials comparing aspirin plus warfarin (A+W) with aspirin alone in such patients...
Inflammatory gene polymorphisms and ischaemic heart disease: review of population association studiesF Andreotti
Institute of Cardiology, Catholic University, Rome, Italy
Heart 87:107-12. 2002..Although they are very preliminary and partly conflicting, the data provide some evidence that alterations in the genetics of the inflammatory system may modify the risk of ischaemic heart disease...
Atherothrombotic disorders: new insights from hematologyFelicita Andreotti
Institute of Cardiology, Catholic University Medical School, Rome, Italy
Circulation 111:1855-63. 2005
Comparison of insulin response to intravenous glucose in healed myocardial infarction, in "cooled-off" unstable and stable angina pectoris, and in healthy subjectsF Andreotti
Institute of Cardiology and Internal Medicine, Catholic University, Rome, Italy
Am J Cardiol 84:870-5. 1999....
Homocysteine and risk of cardiovascular diseaseF Andreotti
Institute of Cardiology, Catholic University, Rome, Italy
J Thromb Thrombolysis 9:13-21. 2000..However, irrefutable proof that hyperhomocysteinemia actually causes atherothrombosis will come only if interventions to lower plasma tHcy will produce concomitant reductions in cardiovascular events...
Coronary artero-venous gradient of endogenous urokinaseF Andreotti
Institute of Cardiology, Catholic University, Rome, Italy
Thromb Res 103:S29-34. 2001..These data identify an artero-venous gradient in human plasma u-PA across the coronary and peripheral beds, but not across the lungs, suggesting differences in u-PA kinetics according to vascular location...
Preinfarction angina and improved reperfusion of the infarct-related arteryF Andreotti
Institute of Cardiology, Catholic University, Rome, Italy
Thromb Haemost 82:68-72. 1999..Understanding the mechanisms responsible for earlier and enhanced coronary recanalization in patients with preinfarction angina may open the way to new reperfusion strategies...
Low-grade exercise enhances platelet aggregability in patients with obstructive coronary disease independently of myocardial ischemiaF Andreotti
Istituto di Cardiologia and Centro Ricerche Fisiopatologia dell Emostasi, Universita Cattolica del Sacro Cuore, Rome, Italy
Am J Cardiol 87:16-20. 2001..The effect is independent of myocardial ischemia, occurs despite aspirin, and is likely dependent on hemodynamic factors interacting with coronary obstructions or dysfunctional endothelium...
Increased prevalence of the G20210A prothrombin gene variant in acute coronary syndromes without metabolic or acquired risk factors or with limited extent of diseaseF Burzotta
Department of Cardiology, Catholic University, Rome, Italy
Eur Heart J 23:26-30. 2002....
G20210A prothrombin gene polymorphism and coronary ischaemic syndromes: a phenotype-specific meta-analysis of 12 034 subjectsF Burzotta
Institute of Cardiology, Catholic University, Rome, Italy
Heart 90:82-6. 2004..To investigate the possible link between the G20210A prothrombin gene variant and different forms of ischaemic heart disease...
Ticlopidine and aspirin fail to suppress the increased platelet aggregability that follows percutaneous coronary interventionsD Fischetti
Institute of Cardiology, Catholic University, Rome, Italy
J Thromb Thrombolysis 10:265-9. 2000..03). Ticlopidine and aspirin reduce whole-blood platelet aggregability compared with aspirin alone but fail to suppress the increased aggregability that occurs 24 hours after PTCA...
Markedly reduced insulin-like growth factor-1 in the acute phase of myocardial infarctionE Conti
Institute of Cardiology, Catholic University, Rome, Italy
J Am Coll Cardiol 38:26-32. 2001..We investigated whether insulin-like growth factor-1 (IGF-1) is reduced in the early phase of acute myocardial infarction (AMI) and whether such a decrease might influence prognosis...
The C807T/G873A polymorphism in the platelet glycoprotein Ia gene and the risk of acute coronary syndrome in the Italian populationI Casorelli
Department of Haematology, Catholic University, Rome, Italy
Br J Haematol 114:150-4. 2001..We conclude that the GP Ia 807 TT (873 AA) genotype is associated with an increased risk of acute coronary syndrome in the Italian population; conversely, the GP Ia 807 CC (873 GG) genotype seems to represent a protective factor...
Platelet aggregability in cardiac syndrome XG A Lanza
Istituto di Cardiologia, , Roma, Italy
Eur Heart J 22:1924-30. 2001..In contrast to patients with coronary disease, however, platelet aggregability was reduced by exercise. This response was prevented by theophylline, strongly suggesting the involvement of adenosine...
Vascular and haemostatic gene polymorphisms associated with non-fatal myocardial infarction: a critical reviewA Manzoli
Department of Cardiovascular Sciences, University Campus Bio Medico, Rome, Italy
Ital Heart J 1:184-93. 2000....
Reversible left anterior descending artery spasm, prolonged cardiac arrest and left main thrombosis during a PTCA attempt of the circumflex arteryC Trani
Cardiology, Catholic University, L go A Gemelli, 8, 00168, Rome, Italy
J Invasive Cardiol 12:151-4. 2000..While attempting to stent the left main, the thrombus was mechanically dislodged, leaving the epicardial coronary tree free, with a good flow...
Ximelagatran/melagatran against conventional anticoagulation: a meta-analysis based on 22,639 patientsL Testa
Institute of Cardiology, Catholic University, Largo F Vito 1 00168 Rome, Italy
Int J Cardiol 122:117-24. 2007....
Relation of the -174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularizationF Burzotta
Department of Cardiovascular Medicine, Catholic University, Rome, Italy
Am J Cardiol 88:1125-8. 2001..16). The IL-6-174 GG genotype is associated with higher acute phase levels of IL-6 and with longer stays in the hospital and in the intensive care unit than C allele carriership after surgical coronary revascularization...
Early vs. delayed invasive strategy in patients with acute coronary syndromes without ST-segment elevation: a meta-analysis of randomized studiesE P Navarese
Institute of Cardiology, Catholic University of the Sacred Heart, Rome
QJM 104:193-200. 2011..76 (0.55-1.04), P = 0.08]. The present meta-analysis shows that for NSTE-ACS patients a routine early invasive strategy does not significantly improve survival nor reduce MI and revascularization rates as compared with a delayed approach...
Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal womenG Paradisi
Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy
Clin Exp Obstet Gynecol 39:153-9. 2012....
[Inflammatory and fibrinolytic activation after coronary artery bypass with extracorporeal circulation]Mario Gaudino
Dipartimento di Medicina Cardiovascolare, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli Largo A, Gemelli, Roma
Ital Heart J Suppl 3:646-51. 2002..The aim of this study was to determine the course of the main inflammatory and fibrinolytic markers in patients undergoing primary elective coronary artery bypass graft with extracorporeal circulation...
Unraveling Reaven's syndrome X: serum insulin-like growth factor-I and cardiovascular diseaseElena Conti
Circulation 107:e190-2; author reply e190-2. 2003
Inflammation, genetics, and ischemic heart disease: focus on the major histocompatibility complex (MHC) genesItalo Porto
Catholic University Medical School, Department of Cardiovascular Medicine, Rome, Italy
Cytokine 29:187-96. 2005..e., frozen blocks of alleles travelling together through generations...
Preoteomics, metabolomics and progenitor cells in acute coronary syndromesRichard C Becker
Duke University Medical Center, USA
J Thromb Thrombolysis 22:85-8. 2006
Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular functionAntonio Maria Leone
Institute of Cardiology, Catholic University of the Sacred Heart, Largo A Gemelli 8, 00168 Rome, Italy
Eur Heart J 26:1196-204. 2005..The aim of this study was to assess spontaneous mobilization of BMSC expressing the haematopoietic and endothelial progenitor cell-associated antigen CD34+ after AMI and its relation to post-infarction remodelling...
Insulin-like growth factor-1 as a vascular protective factorElena Conti
Department of Cardiovascular Diseases, Institute of Cardiology, Catholic University, Medical School, Via Todi 60, 00181 Rome, Italy
Circulation 110:2260-5. 2004
G20210A prothrombin gene variant and clinical outcome in patients with a first acute coronary syndromeFrancesco Burzotta
Institute of Cardiology, Catholic University, Rome, Italy
Haematologica 89:1134-8. 2004..The prognostic value of the G20210A prothrombin gene polymorphism in patients with a first acute coronary syndrome has not been previously assessed. We conducted a prospective study to investigate this issue...
Pregnancy-associated plasma protein a as predictor of outcome in patients with suspected acute coronary syndromesElena Conti
Circulation 109:e211-2; author reply e211-2. 2004
4G/5G PAI-1 promoter polymorphism and acute-phase levels of PAI-1 following coronary bypass surgery: a prospective studyFrancesco Burzotta
Department of Cardiovascular Medicine, Catholic University, Rome, Italy
J Thromb Thrombolysis 16:149-54. 2003..We hypothesized it might also influence the acute-phase levels of PAI-1 following coronary bypass surgery...
Adjusted indirect meta-analysis of aspirin plus warfarin at international normalized ratios 2 to 3 versus aspirin plus clopidogrel after acute coronary syndromesLuca Testa
Institute of Cardiology, John Radcliffe Hospital, Oxford, United Kingdom, and Division of Cardiology, University of Turin, Italy
Am J Cardiol 99:1637-42. 2007..Allocating 100 patients to A+W (at international normalized ratio 2 to 3) with respect to A+C could prevent 17 thromboembolic strokes while causing 3 major bleeds...
Heart-kidney interactions in ischemic syndromesFelicita Andreotti
Circulation 109:e31-2; author reply e31-2. 2004
Pregnancy-associated plasma protein-A and acute coronary syndromes: cause or consequence?Elena Conti
J Am Coll Cardiol 46:1583-4; author reply 1584-5. 2005
IgA anticardiolipin antibody is associated with the extent of daily-life ischaemia in patients with chronic coronary artery diseaseIgnatios Ikonomidis
2nd Cardiology Department, Attikon Hospital, University of Athens, Perikleous 19, N Chalkidona, Athens, 14343, Greece
Heart 93:1412-3. 2007..We investigated whether aCL are related to platelet activation, thrombin generation and daily-life ischaemia in patients with chronic coronary artery disease (CAD)...
Preoperative C-reactive protein level and outcome following coronary surgeryMario Gaudino
Department of Cardiac Surgery, Catholic University, Rome, Italy
Eur J Cardiothorac Surg 22:521-6. 2002..It has been suggested that a preoperative level of C-reactive protein (CRP)>5mg/l is predictive of postoperative complications in cardiac surgery patients...
Expanding the role of coagulation in arterial thrombosis: evidence from animal models using a new factor Xa inhibitorFelicita Andreotti
Thromb Haemost 99:651-2. 2008
Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)Adam Torbicki
Department of Chest Medicine, Institute for Tuberculosis and Lung Diseases, Warsaw, Poland
Eur Heart J 29:2276-315. 2008..With the exception of severe air and fat embolism, the haemodynamic consequences of non-thrombotic emboli are usually mild. Treatment is mostly supportive but may differ according to the type of embolic material and clinical severity...
Genetic control of postoperative systemic inflammatory reaction and pulmonary and renal complications after coronary artery surgeryMario Gaudino
Policlinico Universitario A Gemelli, Divisione di Cardiochirurgia, Largo A Gemelli 8, 00168, Rome, Italy
J Thorac Cardiovasc Surg 126:1107-12. 2003..CONCLUSION: The interleukin 6 -174 G/C polymorphism modulates postoperative interleukin 6 levels and is associated with the degree of postoperative renal and pulmonary dysfunction and in-hospital stay after coronary surgery...
Scintigraphic results in asymptomatic myocardial infarction patients with exercise-induced ST segment elevationGaetano Antonio Lanza
Istituto di Cardiologia Università Cattolica del Sacro Cuore Policlinico A Gemelli Largo A Gemelli, 8, 00168 Roma
Ital Heart J 3:330-4. 2002..This study was specifically aimed at investigating the clinical meaning of isolated exercise-induced ST segment elevation in asymptomatic patients with a recent acute myocardial infarction (MI)...
Normothermia does not improve postoperative hemostasis nor does it reduce inflammatory activation in patients undergoing primary isolated coronary artery bypassMario Gaudino
Department of Cardiac Surgery, Catholic University, Rome, Italy
J Thorac Cardiovasc Surg 123:1092-100. 2002..Despite its common acceptance in clinical practice, the effective benefits of normothermic systemic perfusion during coronary artery bypass operations are far from established...
Reduced levels of insulin-like growth factor-1 in patients with angina pectoris, positive exercise stress test, and angiographically normal epicardial coronary arteriesElena Conti
Institute of Cardiology, Catholic University, Rome, Italy
Am J Cardiol 89:973-5. 2002
Letter by Andreotti et al regarding article, "Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) sFelicita Andreotti
Circulation 115:e313; author reply e314. 2007
Relation between nitric oxide metabolites and haemoglobin concentrations in patients with ischaemic heart diseaseFelicita Andreotti
Heart 93:255-7. 2007
Favorable cardiac risk among elderly breast carcinoma survivorsElena Conti
Cancer 100:878-9; author reply 879. 2004
Prothrombotic response to coronary angioplasty in patients with unstable angina and raised C-reactive proteinAlessandro Sciahbasi
Institute of Cardiology, Catholic University, Rome, Italy
J Thromb Thrombolysis 14:131-8. 2002..The rise in vWF is associated with that in CRP and with enhanced platelet reactivity. Such changes may contribute to the worse prognosis of unstable patients with raised indices of inflammation...
Increased platelet reactivity due to platelet receptor polymorphisms? Not in the real worldItalo Porto
Arterioscler Thromb Vasc Biol 23:1703-4; author reply 1703-4. 2003
Rate-control vs. rhythm-control in patients with atrial fibrillation: a meta-analysisLuca Testa
Institute of Cardiology, Catholic University, Largo F. Vito 1, 00168 Rome, Italy
Eur Heart J 26:2000-6. 2005....
Cigarette smoking is associated with increased circulating proinflammatory and procoagulant markers in patients with chronic coronary artery disease: effects of aspirin treatmentIgnatios Ikonomidis
Imperial College School of Medicine, National Heart and Lung Institute, Cardiology Department, Hammersmith Hospital, London, United Kingdom
Am Heart J 149:832-9. 2005....
Pregnancy associated plasma protein-A and coronary atherosclerosis: marker, friend, or foe?Filippo Crea
Eur Heart J 26:2075-6. 2005
The -174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication?Mario Gaudino
Department of Cardiac Surgery, Cardiac Anaesthesiology, and Cardiology, Catholic University, Rome, Italy
Circulation 108:II195-9. 2003..These data suggest an inflammatory component of postoperative atrial arrhythmias and a genetic predisposition to this complication...
IGF-1 and macrovascular complications of diabetes: alternative interpretations of recently published dataElena Conti
Diabetes Care 26:1653-4; author reply 1654-5. 2003
[Guidelines on the management of stable angina pectoris: executive summary]Kim Fox
G Ital Cardiol (Rome) 7:535-83. 2006
Relation between platelet response to exercise and coronary angiographic findings in patients with effort anginaGaetano Antonio Lanza
Istituto di Cardiologia, Universita Cattolica del Sacro Cuore, Roma, Italy
Circulation 107:1378-82. 2003..In this study, we prospectively investigated whether the platelet response to exercise might help distinguish, among patients with angina, those with obstructive CAD from those with normal coronary arteries (NCAs)...
Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of CardiologyKim Fox
Department of Cardiology, Royal Brompton Hospital, London, UK
Eur Heart J 27:1341-81. 2006
