- The difficult-to-wean patientNicolino Ambrosino
Cardiothoracic Department, Pulmonary Unit, University Hospital of Pisa, Via Paradisa 2, Cisanello, Pisa, Italy
Expert Rev Respir Med 4:685-92. 2010....
- Comprehensive physiotherapy management in ARDSN Ambrosino
Pulmonary Rehabilitation and Weaning Center, Auxilium Vitae, Volterra, Pisa, Italy
Minerva Anestesiol 79:554-63. 2013..Early ICU physiotherapy is an interdisciplinary team activity, involving physical therapists, occupational therapists, nurses and medical staff...
- Use of endobronchial valves in persistent air leaks: a case report and review of the literatureNicolino Ambrosino
Cardiothoraco Vascular Department, Pulmonary Unit, University Hospital of Pisa, ed 13, Cisanello, Pisa, Italy
Expert Rev Respir Med 7:85-90. 2013..Use of endobronchial valves is an effective, nonsurgical, minimally invasive intervention for patients with prolonged pulmonary air leaks not suitable for surgical procedures...
- Is there any treatment other than drugs to alleviate dyspnea in COPD patients?Nicolino Ambrosino
Pulmonary Unit, Cardio Thoracic Department, University Hospital, Pisa, Italy
Int J Chron Obstruct Pulmon Dis 1:355-61. 2006..Lung volume resection surgery and lung transplantation in selected patients may control symptoms and improve HRQoL...
- Chronic respiratory care for neuromuscular diseases in adultsN Ambrosino
Dipartimento Cardio Toracico, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
Eur Respir J 34:444-51. 2009..In conclusion, recent advances in respiratory care of NMD have improved prognosis and many caregivers have changed from a traditional noninterventional to a more aggressive, supportive approach...
- End stage chronic obstructive pulmonary diseaseNicolino Ambrosino
Respiratory Intensive Care and Pulmonary Diseases Unit, Cardio Thoracic Department, University Hospital Pisa, Cisanello 56127 Pisa, Italy
Pneumonol Alergol Pol 77:173-9. 2009..Good clinical care can prevent or alleviate suffering by assessing symptoms and providing psychological and social support to the patients and their families...
- New approaches in pulmonary rehabilitationNicolino Ambrosino
Pulmonary Unit, Cardio Thoracic Department, University Hospital, Pisa, Via Paradisa 2 Cisanello, 56124 Pisa, Italy
Clin Chest Med 28:629-38, vii. 2007..Nevertheless, extreme breathlessness or peripheral muscle fatigue may prevent some patients from performing high-intensity exercise; therefore, new tools are needed to improve the effectiveness of pulmonary rehabilitation...
- Tiotropium and exercise training in COPD patients: effects on dyspnea and exercise toleranceNicolino Ambrosino
Cardio Thoracic Department, University Hospital, Pisa, Italy
Int J Chron Obstruct Pulmon Dis 3:771-80. 2008..Tiotropium 18 microg once daily induces sustained bronchodilation throughout the day and reduces hyperinflation, one of the pathophysiological factors contributing to exertional dyspnea in COPD patients...
- The clinical management in extremely severe COPDNicolino Ambrosino
U O Pneumologia, Dipartimento Cardio Toracico, Azienda Ospedaliero Universitaria Pisana, Via Paradisa 2, Cisanello, 56124 Pisa, Italy
Respir Med 101:1613-24. 2007..Only a small proportion of patients with severe COPD discuss end-of-life issues with their physicians...
- Noninvasive positive pressure ventilation in the acute care setting: where are we?N Ambrosino
Pulmonary and Respiratory Intensive Care Unit, Cardio Thoracic Dept, University Hospital Pisa, Italy
Eur Respir J 31:874-86. 2008..Additionally, the technique must be applied in the appropriate location by a trained team in order to avoid disappointing results...
- Non-invasive ventilation in exacerbations of COPDNicolino Ambrosino
Pulmonary Unit, Cardio Thoracic Department, University Hospital Pisa, Italy
Int J Chron Obstruct Pulmon Dis 2:471-6. 2007..In these patients a NIV trial may be attempted in closely monitored clinical settings where prompt endotracheal intubation may be assured...
- Series on comprehensive management of end-stage COPDN Ambrosino
UO Pneumologia, Dipartimento Cardio-Toracico, Azienda Ospedaliero-Unversitaria Pisana, Via Paradisa 2, Cisanello, 56124, Pisa, Italy
Eur Respir J 30:828-30. 2007
- The patients with severe chronic obstructive pulmonary disease and chronic respiratory insufficiencyN Ambrosino
Pulmonary Unit, Cardio Thoracic Department, University Hospital Pisa, Italy
Monaldi Arch Chest Dis 67:148-53. 2007..Lung transplantation is a final step in end-stage patients, but short- and long-term outcomes remain significantly inferior in relation to other "solid" organs recipients...
- Physiotherapy in the perioperative periodNicolino Ambrosino
Respiratory Unit, Cardio Thoracic Department, University Hospital, Pisa, Italy
Best Pract Res Clin Anaesthesiol 24:283-9. 2010....
- New strategies to improve exercise tolerance in chronic obstructive pulmonary diseaseN Ambrosino
Pulmonary Unit, Cardio Thoracic Dept, University Hospital, Pisa, Italy
Eur Respir J 24:313-22. 2004..The modalities discussed should be used as adjuncts to a well designed comprehensive respiratory rehabilitation programme...
- The management of asthma and chronic obstructive pulmonary disease: current status and future perspectivesNicolino Ambrosino
Cardiothoracic Department, Pulmonary Unit, University Hospital of Pisa, Italy
Expert Rev Respir Med 6:117-27. 2012....
- Long-term mechanical ventilation and nutritionNicolino Ambrosino
Pulmonary Division, Cardio Thoracic Department, University Hospital, Via Paradisa 2, Cisanello, 56100 Pisa, Italy
Respir Med 98:413-20. 2004..This paper aims to review the most recent innovations in the field of nutritional status and food intake-related problems of VAI (both in adulthood and in childhood)...
- Unusual applications of noninvasive ventilationN Ambrosino
Pulmonary and Respiratory Intensive Care Unit, Cardio Thoracic Department, University Hospital Pisa, Pisa, Italy
Eur Respir J 38:440-9. 2011..NIV should be applied under close monitoring and ETI should be promptly available in the case of failure. A trained team, careful patient selection and optimal choice of devices, can optimise outcome of NIV...
- Non invasive ventilation in cardio-surgical patientsF Guarracino
Cardiothoracic Intensive Care Unit, Cardio Thoracic Department, University Hospital Pisa, Italy
Minerva Anestesiol 77:734-41. 2011..As a consequence, the application of NIV in this setting requires an expertly skilled team, continuous hemodynamic monitoring and echocardiographic assessment...
- [Medical surveillance of previously asbestos-exposed workers: report of a case of lung cancer with high level of serum mesothelin]G Guglielmi
U O Medicina Preventiva e del Lavoro, Azienda Ospedaliero Universitaria Pisana, Pisa
G Ital Med Lav Ergon 29:345-6. 2007..Nevertheless, serum markers like mesothelin and osteopontin (especially the first) may result very helpful in monitoring and screening the population of workers previously exposed to asbestos...
- Clinical evaluation of oscillating positive expiratory pressure for enhancing expectoration in diseases other than cystic fibrosisN Ambrosino
Clinica del Lavoro Foundation IRCCS, Respiratory Unit, Italy
Monaldi Arch Chest Dis 50:269-75. 1995..9 +/- 2.9 to 10.9 +/- 7.1 and 2.8 +/- 3.1 to 10.1 +/- 10.8 mL for A and B, respectively). Visual analogue scale score significantly decreased at the end of each treatment.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Comparison of five bilevel pressure ventilators in patients with chronic ventilatory failure: a physiologic studyMichele Vitacca
Pulmonary Division, Scientific Institute, Fondazione Salvatore Maugeri IRCCS, I-25064 Gussago (BS, Italy
Chest 122:2105-14. 2002..This effect was obtained with similar levels of PTPao,min, despite the fact that Pao,peak was different among some ventilators. The number of IEs was similar among the studied ventilators...
- Cognitive and perceived health status in patient with chronic obstructive pulmonary disease surviving acute on chronic respiratory failure: a controlled studyNicolino Ambrosino
Pulmonary Division, Salvatore Maugeri Foundation IRCCS, Scientific Institute of Gussago, 25064 Gussago, Italy
Intensive Care Med 28:170-7. 2002..To evaluate the perceived health and cognitive status in survivors of chronic obstructive pulmonary disease (COPD) exacerbations requiring mechanical ventilation...
- Physiotherapy in critically ill patientsN Ambrosino
Pulmonary Rehabilitation and Weaning Center, Auxilium Vitae, Volterra, Italy
Rev Port Pneumol 17:283-8. 2011..There is still limited scientific evidence to support such a comprehensive approach to all critically ill patients; therefore we need randomised studies with solid clinical short- and long-term outcome measures...
- Assessing the benefits: outcome and future directionsN Ambrosino
Pulmonary Rehabilitation and Weaning Center, Auxilium Vitae, Volterra, Italy
Eur J Phys Rehabil Med 47:499-505. 2011..Although, several questions remain unresolved, pulmonary rehabilitation programs should be included in the comprehensive treatment of patients with respiratory diseases...
- Flexible bronchoscopy during mechanical ventilation in the prone position to treat acute lung injuryF Guarracino
Cardiothoracic Intensive Care Unit, Cardio Thoracic Department, University Hospital of Pisa, Italy
Rev Port Pneumol 19:42-4. 2013....
- Awake palliative thoracic surgery in a high-risk patient: one-lung, non-invasive ventilation combined with epidural blockadeF Guarracino
Division of Cardiothoracic Anaesthesia and Intensive Care, Cardio Thoracic Department, University Hospital of Pisa, Via Paradisa 2, Pisa 56124, Italy
Anaesthesia 63:761-3. 2008....
- Dyspnoea and hypoxaemia after lung surgery: the role of interatrial right-to-left shuntC Marini
Pulmonary Unit, Clinical Physiology Institute, National Research Council, University of Pisa, Pisa, Italy
Eur Respir J 28:174-81. 2006..Open thoracotomy was the traditional approach in the past. Percutaneous closure has now become the most used and effective technique for the repair of the interatrial anatomical malformation...
- Supported arm training in patients recently weaned from mechanical ventilationRoberto Porta
Pulmonary Division, Scientific Institute of Gussago, Salvatore Maugeri Foundation IRCSS, Italy
Chest 128:2511-20. 2005..022; OR, 1.067). CONCLUSION: Early upper-limb exercise training is feasible in RIICU patients recently weaned from MV and can enhance the effects of gPT. Baseline inspiratory muscle function is related to exercise capacity improvement...
- Influenza A triggered status asthmaticus requiring emergency ECMOF Guarracino
Cardiothoracic Intensive Care Medicine, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy
Monaldi Arch Chest Dis 73:162-5. 2010..When medical treatment and mechanical ventilation fail, extracorporeal membrane oxygenation therapy should not be delayed as it will avoid injury resulting from inadequate mechanical ventilation and lung hyperinflation...
- Physiological effects of meals in difficult-to-wean tracheostomised patients with chronic obstructive pulmonary diseaseMichele Vitacca
Pulmonary Unit, Weaning Centre, S Maugeri Foundation IRCCS, Via Pinidolo 23, 25064 Gussago, Italy
Intensive Care Med 31:236-42. 2005..To evaluate effects of meals in difficult-to-wean tracheostomised patients with chronic obstructive pulmonary diseases during spontaneous breathing or Inspiratory Pressure Support...
- Weakness of respiratory and skeletal muscles after a short course of steroids in patients with acute lung rejectionS Nava
Respiratory Unit, Istituto Scientifico di Montescano, Pavia, Italy
Eur Respir J 20:497-9. 2002..Compared to the pretreatment condition, approximately 45% of patients showed acute generalised muscle weakness that recovered after approximately 2 months. This demonstrates muscle weakness induced by steroids within patients...
- Tolerance and physiologic effects of nocturnal mask pressure support vs proportional assist ventilation in chronic ventilatory failureJoao Carlos Winck
Department of Pneumology, Hospital Sao Joao, Faculdade de Medicina, Universidade do Porto, Porto, Portugal
Chest 126:382-8. 2004..To compare the tolerance and physiologic effects of a 5-night treatment with either nasal proportional assist ventilation (PAV) or pressure support ventilation (PSV) in patients with chronic ventilatory failure...
- Where to perform long-term ventilationNicolino Ambrosino
Pulmonary Rehabilitation and Respiratory Intensive Care Department, Salvatore Maugeri Foundation, Scientific Institute of Gussago, I 25064 Gussago BS, Italy
Respir Care Clin N Am 8:463-78. 2002..Careful selection of patients, closer attention to education and training, and collection of outcome data are all factors that presumably will facilitate the development of better-quality and cost-saving home care...
- Mask proportional assist vs pressure support ventilation in patients in clinically stable condition with chronic ventilatory failureRoberto Porta
Fondazione Salvatore Maugeri IRCCS, Pulmonary Department, Scientific Institutes of Gussago, Italy
Chest 122:479-88. 2002..We failed to find any difference in patient/ventilator interaction between ventilatory modes...
- Effects of acute on chronic respiratory failure on hypercapnia and 3-month survivalMichele Vitacca
Respiratory Department, Salvatore Maugeri Foundation, Istituto di Ricovero e Cura a Carattere Scientifico, Scientific Institute of Gussago, Via Pinidolo 23, 25064 Gussago BS, Italy
Chest 128:1209-15. 2005..There is a lack of information on respiratory function and mechanics after COPD exacerbations...
- Treatments for COPDNicola A Hanania
Pulmonary and Critical Care Medicine, Baylor College of Medicine, 1504 Taub Loop, Houston, TX 77030, USA
Respir Med 99:S28-40. 2005..The challenge will be to develop this base of knowledge in order to shape future research and allow clinicians to deliver tailored COPD management programmes for the growing number of patients afflicted with this disease...
- American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitationLinda Nici
Am J Respir Crit Care Med 173:1390-413. 2006
- Seven-year time course of lung function, symptoms, health-related quality of life, and exercise tolerance in COPD patients undergoing pulmonary rehabilitation programsKatia Foglio
Pulmonary Rehabilitation and Lung Function Unit, Scientific Institute of Gussago, Italy
Respir Med 101:1961-70. 2007..To evaluate the long-term course of outcome indexes in patients with chronic obstructive pulmonary disease (COPD) undergoing repeated pulmonary rehabilitation programs (PRP)...
- Pattern of variables describing desaturator COPD patients, as revealed by cluster analysisDomenico Maurizio Toraldo
A Galateo Lung Disease Hospital, Third Division ASL LE 1, San Cesario di Lecce, Lecce, Italy
Chest 128:3828-37. 2005....
- Weaning and respiratory muscle dysfunction: the egg-chicken dilemmaNicolino Ambrosino
Chest 128:481-3. 2005
- Prevalence and prognostic role of cardiovascular complications in patients with exacerbation of chronic obstructive pulmonary disease admitted to Italian respiratory intensive care unitsCleante Scarduelli
Pulmonary Division and Respiratory Intensive Care Unit, C Poma Hospital, Mantova, Italy
Ital Heart J 5:932-8. 2004....
- Walking modality affects respiratory muscle action and contribution to respiratory effortRoberto Duranti
Department of Internal Medicine, Section of Clinical Immunology, Allergology and Respiratory Diseases, University of Florence, Viale Morgagni 85, 50134, Florence, Italy
Pflugers Arch 448:222-30. 2004..Combinations of different patterns of flow and pressure generation made the respiratory effort sensation similar during AS and AG modes...
- Early physiotherapy in the respiratory intensive care unitEnrico Clini
Fondazione Villa Pineta, Pavullo, Italy
Respir Med 99:1096-104. 2005..Evidence supporting physiotherapy intervention is limited as there are no studies examining the specific effects of interventions on long-term outcome...